Abstract:
:In order to provide additional data and perspective to current clinical, policy, and legal debates surrounding the prenatal use of cocaine in the USA, a retrospective cohort study was conducted to examine effects of cocaine on selected perinatal outcomes, and to compare the relative risks of adverse perinatal outcomes among users of cocaine and users of cigarettes. Using data from a large urban perinatal registry, relative risks of selected perinatal outcomes were determined for maternal cocaine users who were non-smokers of cigarettes, and used no marijuana, heroin, amphetamines, or alcohol (n = 64), and for cigarette smokers who do not use illicit drugs or alcohol during pregnancy (n = 3209). When compared with women with no recorded prenatal exposure to drugs or cigarettes (n = 13,043), cocaine users had higher risks than smokers for the following adverse outcomes: low birthweight [Relative Risk (RR) 5.3, 95% Confidence Interval (CI) 3.0-9.3], small-for-gestational age (SGA) [RR 4.2, 95% CI 2.4-7.3], prematurity [RR 4.0, 95% CI 2.3-7.0], abruptio placentae [RR 10.0, 95% CI 3.5-29.0], placenta praevia [RR = 2.4, 95% CI 0.3-17.8] and perinatal death [RR = 5.3, 95% CI 1.9-15.2]. Smokers who did not use any drugs experienced most of the same adverse perinatal outcomes as cocaine users, but the magnitude of risk was greater in cocaine users than in smokers for all outcomes. However, given the greater numbers of cigarette smokers than cocaine users in the population the numbers of infants in the population suffering these adverse outcomes is likely to be greater among offspring of cigarette smokers. The data support the current concern about the risk of cocaine, and current efforts to provide treatment to pregnant cocaine users. The data also underline the continued substantial risks of cigarette smoking to large numbers of pregnant women.
journal_name
Paediatr Perinat Epidemioljournal_title
Paediatric and perinatal epidemiologyauthors
Kistin N,Handler A,Davis F,Ferre Cdoi
10.1111/j.1365-3016.1996.tb00050.xsubject
Has Abstractpub_date
1996-07-01 00:00:00pages
269-78issue
3eissn
0269-5022issn
1365-3016journal_volume
10pub_type
杂志文章,多中心研究abstract::Preterm delivery (PTD) complicates as many as 10% of pregnancies in the United States. Moreover, prematurity accounts for more than 70% of the consequent neonatal and infantile morbidity and mortality. Serious long-term complications include cerebral palsy, respiratory disease, blindness and deafness. Despite substant...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-3016.2001.00008.x
更新日期:2001-07-01 00:00:00
abstract::In this study, hospital admissions for lower respiratory tract illness before two years of age have been documented for all children born in Western Australia in 1986. Admissions data were linked to birth and death records for individual children. Of the total cohort, 5% of non-Aboriginal and 17% of Aboriginal childre...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1996.tb00041.x
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND:Self-reported weight prior to pregnancy is prone to error. We utilised a measured pre-conceptional weight from the electronic health record (EHR) to investigate error in recalled pre-pregnancy body mass index (BMI) category and compared how associations between pre-pregnancy BMI and pregnancy outcomes varied...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12286
更新日期:2016-07-01 00:00:00
abstract::We examined hospital and domestic infant care practices in Oxfordshire and Northampton Health Districts to measure changes in prevalence of sudden infant death syndrome (SIDS) risk factors, and to evaluate a specific educational intervention restricted to Oxfordshire. We sent a postal questionnaire to 2781 parents of ...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1046/j.1365-3016.1998.00089.x
更新日期:1998-04-01 00:00:00
abstract::Whilst only about a third of all cerebral palsy occurs in children who had been of low birthweight, recent increases in the survival of low and very low birthweight infants have coincided with significant increases in the numbers of cerebral palsy children amongst them. This paper analyses data from the Western Austra...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1992.tb00769.x
更新日期:1992-04-01 00:00:00
abstract::Passive smoking during pregnancy leads to adverse effects on mother and infant. The present investigation was designed to evaluate the association between maternal reported passive smoking with the cotinine concentration of maternal urine and umbilical cord blood at delivery and to determine the accuracy of maternal r...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2011.01242.x
更新日期:2012-01-01 00:00:00
abstract::Evidence suggests that low concentrations of 25-hydroxyvitamin D(3) (25OHD3) during gestation may be associated with a range of adverse health outcomes in later life. Retrospective estimation of perinatal vitamin D status using questionnaires is extremely unreliable and stored serum samples are rarely available. We ai...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2010.01105.x
更新日期:2010-05-01 00:00:00
abstract::We estimated the accuracy of a non-invasive, inexpensive method (the Chinese lunar calendar, CLC) to predict the sex of a baby from around the time of conception, using 2,840,755 singleton births occurring in Sweden between 1973 and 2006. Maternal lunar age and month of conception were estimated, and used to predict e...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2010.01129.x
更新日期:2010-07-01 00:00:00
abstract::Causal hypotheses for spastic cerebral palsy were sought by comparing a population based sample of 183 cases with 549 matched controls. A time-ordered multivariate analysis was used to distinguish confounders and consequences of disease from possible causes, which could be single factors or sequences of factors. Eight...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1993.tb00405.x
更新日期:1993-07-01 00:00:00
abstract::In a historical follow-up study, we evaluated the association of the fertility of daughters with five perinatal factors: short (< 15 months) or long (> or = 45 months) preceding birth interval, low (< or = 20 years) or advanced (> or = 40 years) maternal age and season of birth. We used data concerning 2062 women marr...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1046/j.1365-3016.1999.00215.x
更新日期:1999-10-01 00:00:00
abstract::Despite nearly four million deliveries in the United States each year, minimal information exists on unintended health consequences following childbirth, particularly in relation to delivery method. The purpose of this study was to assess the association between method of delivery and the general health status, sexual...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1046/j.1365-3016.2001.00345.x
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:While there is evidence of an association between caesarean birth and increased asthma in children in high-income countries, it is unknown whether this association exists in low-to-middle-income countries (LMICs). We investigated whether children born through caesarean in India and Vietnam are at increased r...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12324
更新日期:2017-01-01 00:00:00
abstract::The incidence of neural tube defects was monitored among all live- and still-births delivered between June 1986 and July 1988. In all there were 19,115 total births. The incidence of neural tube defects (NTD) was 1.9 per 1000 among those whose conception time was prior to May 1986. However, in conceptions occurring in...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1989.tb00370.x
更新日期:1989-01-01 00:00:00
abstract::Retrospective reports of smoking in pregnancy are of importance for clinical or scientific purposes. Careful analyses of stability and accuracy of recalled behaviour are, therefore, needed. In 1998, the mothers of 2369 pre-teens born in Sweden retrospectively reported their smoking behaviour during the first trimester...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2007.00917.x
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Comparable evidence on adiposity inequalities in early life is lacking across a range of European countries. This study investigates whether low maternal education is associated with overweight and obesity risk in children from distinct European settings during early childhood. METHODS:Prospective data of 4...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12285
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:To optimise the health of pregnant women and their children by evidence-based primary and secondary prevention, more scientific knowledge is needed. To overcome the methodological limitations of many studies on pregnancy and child health, which often use a retrospective design, we established the PRIDE (PReg...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12023
更新日期:2013-01-01 00:00:00
abstract::The aims of the study were to describe the trend in birthweight from 1985 to 2000 in Chile and ascertain the possible factors that may explain the changes in birthweight during the period. We used time series of birthweight and length at birth of all live births (n > 4,000,000). Multivariable regression analyses were ...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2005.00673.x
更新日期:2005-11-01 00:00:00
abstract::Radiological examination of the abdomen is critical to the diagnosis of necrotising enterocolitis (NEC). Previous studies on the reproducibility of radiological findings have been limited in size and based only on infants with the disease. We conducted a study among a sample of high-risk infants with and without the d...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1365-3016.2003.00517.x
更新日期:2004-01-01 00:00:00
abstract::Previous studies have suggested a relationship between reproductive history, pregnancy and birth factors, and the risk of neuroblastoma. We conducted a case-control telephone interview study that included a total of 504 children under the age of 19 years with newly diagnosed neuroblastoma identified by two national co...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1046/j.1365-3016.2001.0376a.x
更新日期:2001-10-01 00:00:00
abstract::There is conflicting evidence concerning the relationship between breast feeding and wheezing illness. The objective of this study was to investigate whether there is any association between breast feeding and wheezing in children aged over 5 years and to discover possible sources of heterogeneity. An electronic searc...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1365-3016.2011.01233.x
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Triptans are commonly prescribed for migraine, a pain condition that is highly prevalent in women of childbearing age. No prior studies have investigated associations between exposure to triptans during fetal life and risk of externalising and internalising behaviours in children. METHODS:This study was set...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12253
更新日期:2016-03-01 00:00:00
abstract::Cognitively delayed children are at risk for poor mental and physical health throughout their lives. The economically disadvantaged and some race/ethnic groups are more likely to experience cognitive delay, but the age at which delays first emerge and the underlying mechanisms responsible for disparities are not well ...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2008.01006.x
更新日期:2009-05-01 00:00:00
abstract::The nutritional status of a woman before and during pregnancy is important for a healthy pregnancy outcome. Maternal malnutrition is a key contributor to poor fetal growth, low birthweight (LBW) and short- and long-term infant morbidity and mortality. This review summarised the evidence on association of maternal nutr...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-3016.2012.01308.x
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Previous studies of the association between tobacco smoke and hearing loss in children are limited, involve small samples and are cross-sectional. We investigated the association of maternal smoking during pregnancy and exposure to tobacco smoke at age 4 months with hearing impairment at age 3 years in child...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12477
更新日期:2018-09-01 00:00:00
abstract::Male genital tract birth defects have been associated in previous studies with several prenatal exposures to environmental and dietary risk factors. The purpose of this study was to explore the association between hypospadias and cryptorchidism, and the dietary habits of an agricultural population in Italy. A populati...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2007.00918.x
更新日期:2008-05-01 00:00:00
abstract::Perinatal deaths were systematically investigated over a 25-month period in a Zimbabwean district and were classified into pathological subgroups according to Wigglesworth. There were 319 perinatal deaths (a rate of 30.6 per 1000) including 83 normally formed macerated stillbirths, 28 cases of congenital malformation,...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1989.tb00380.x
更新日期:1989-07-01 00:00:00
abstract::Gestational diabetes mellitus (GDM) is a risk factor for delivering a large-for-gestational-age (LGA) infant. Haemoglobin A1c (A1C) is an indicator of glycaemic control. The objective of this study was to test whether higher A1C quartile at the time of diagnosis of GDM is associated with increased risk of delivering a...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2012.01266.x
更新日期:2012-05-01 00:00:00
abstract::Designing, piloting and proceeding with a longitudinal birth cohort is a major exercise. Here we outline ways in which a resource centre could be initiated to provide advice and training, a library of appropriate instruments and publications, provision for cross-cohort comparisons and a biobanking facility. The resour...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2009.01020.x
更新日期:2009-07-01 00:00:00
abstract::Child sexual abuse research presents practical, methodological and statistical challenges. This paper examines some recent literature about the incidence and effects of child sexual abuse. Researchers who use epidemiological studies to attempt to ascertain the prevalence of different forms of abuse should be aware of ...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-3016.1990.tb00657.x
更新日期:1990-07-01 00:00:00
abstract::Necrotising enterocolitis is the most common gastrointestinal complication of pre-term infants. In order to determine the strength of the association of hypoxia/ischaemia and infection as causative factors in necrotising enterocolitis, we evaluated all liveborn pre-term infants with a birthweight less than 1500 g and/...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-3016.1989.tb00369.x
更新日期:1989-01-01 00:00:00