Stroke event rates in anticoagulated patients with paroxysmal atrial fibrillation.

abstract：:Previous studies in patients with peripheral arterial disease (PAD) have shown that the prognosis is relatively good when the distal systolic ankle index (ankle systolic pressure/arm systolic pressure) is above 50% and the distal toe systolic pressure is above 40 mmHg. In 132 patients suspected of PAD in the legs we i...

journal_title：Journal of internal medicine

authors： Christensen JH,Freundlich M,Jacobsen BA,Falstie-Jensen N

更新日期：1989-08-01 00:00:00

abstract：:Since 2006, the advent of increasingly larger genome-wide association studies and their meta-analyses have led to numerous, replicated findings of genetic polymorphisms associated with many diseases and traits. Early studies suggested that the identified loci generally accounted for a small fraction of the genetic var...

journal_title：Journal of internal medicine

authors： Kaprio J

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Phospholipid transfer protein (PLTP) is an emerging cardiometabolic risk marker that is important in high-density lipoprotein (HDL) and triglyceride metabolism. Plasma PLTP activity is elevated in type 2 diabetes mellitus, whereas glucose may regulate PLTP gene transcription in vitro. Of interest, common PLT...

journal_title：Journal of internal medicine

authors： Dullaart RP,Vergeer M,de Vries R,Kappelle PJ,Dallinga-Thie GM

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:Chronic Chlamydia pneumoniae infection is considered as a cardiovascular risk factor and antibodies are commonly analysed by the subjective microimmunofluorescence (MIF) test. We wanted to investigate the C. pneumoniae IgA- and IgG seroprevalence in young survivors of myocardial infarction and matched contro...

journal_title：Journal of internal medicine

authors： Halvorsen DS,Børvik T,Njølstad I,Gutteberg TJ,Vorland LH,Hansen JB

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVES:To ascertain whether patients with Crohn's disease treated with azathioprine maintained bone mineral mass better than patients treated with steroids alone. DESIGN:Retrospective study. SETTING:University Hospital of Malmö, Sweden. SUBJECTS:A total of 59 patients with ileocolonic, ileocaecal or colonic Croh...

journal_title：Journal of internal medicine

authors： Florén CH,Ahrén B,Bengtsson M,Bartosik J,Obrant K

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVES:Physical activity (PA) is a preventive strategy for cardiovascular disease and for managing cardiovascular risk factors. There is little information on the effectiveness of PA for the prevention of cardiovascular outcomes once cardiovascular disease is present. Thus, we studied the relationship between PA at...

journal_title：Journal of internal medicine

authors： Fossum E,Gleim GW,Kjeldsen SE,Kizer JR,Julius S,Devereux RB,Brady WE,Hille DA,Lyle PA,Dahlöf B

更新日期：2007-10-01 00:00:00

abstract：:The effects of resuscitation on patients who died suddenly out of hospital were evaluated after the introduction of early defibrillation performed by ambulance personnel using semi-automatic defibrillators. Resuscitation attempts were initiated in 548 patients during the 1-year study period. Mean ambulance delay was 7...

journal_title：Journal of internal medicine

authors： Jakobsson J,Rehnqvist N,Nyquist O

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:To evaluate primary hyperparathyroidism (HPT) as a risk factor for hip fractures. DESIGN:A population-based, record-linked, prospective study with a mean observation time of 17 years (women) and 16.5 years (men). SETTING:A cohort obtained from a register of hospital admissions in the Uppsala Health Care Reg...

journal_title：Journal of internal medicine

authors： Larsson K,Ljunghall S,Krusemo UB,Naessén T,Lindh E,Persson I

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVES:the results of experimental studies suggest that vitamin D deficiency activates the renin-angiotensin system and predisposes to hypertension. Results of previous epidemiological studies investigating the association between 25-hydroxyvitamin D [25(OH)D] status and hypertension have not been consistent, perha...

journal_title：Journal of internal medicine

authors： Burgaz A,Byberg L,Rautiainen S,Orsini N,Håkansson N,Arnlöv J,Sundström J,Lind L,Melhus H,Michaëlsson K,Wolk A

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Benefit from endovascular thrombectomy (EVT) for large-vessel occlusion (LVO) acute ischaemic stroke (AIS) is well demonstrated. Furthermore, emerging evidence supports efficacy in appropriately selected patients treated beyond current recommendations of 6 h. We evaluated clinical outcomes in ...

journal_title：Journal of internal medicine

authors： Motyer R,Kok HK,Asadi H,O'Hare A,Brennan P,Power S,Looby S,Nicholson P,Williams D,Murphy S,Hill MD,Goyal M,McManus J,O'Brien P,Thornton J

更新日期：2017-12-01 00:00:00

abstract：:This review describes global patterns of tobacco use and the mechanisms by which tobacco use is involved in carcinogenesis. A second part will discuss the association between tobacco use and risk of specific cancer types. Tobacco use has traditionally been a practice of high-income countries, but it has recently been ...

journal_title：Journal of internal medicine

authors： Kuper H,Adami HO,Boffetta P

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVES:The aim was to study the effect of a 5-year diet intervention on 24-year mortality in middle aged men with combined hyperlipidaemia. SETTING:We studied 104 initially healthy men (in 1972) aged 40-49 years with baseline values of total serum cholesterol >6.45 mmol L-1 and fasting triglycerides >2.55 mmol L-1...

journal_title：Journal of internal medicine

authors： Hjerkinn EM,Sandvik L,Hjermann I,Arnesen H

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:Pseudoxanthoma elasticum (PXE) is a recessive disorder involving skin, eyes and arteries, mainly caused by ABCC6 pathogenic variants. However, almost one fifth of patients remain genetically unsolved despite extensive genetic screening of ABCC6, as illustrated in a large French PXE series of 220 cases. We searc...

journal_title：Journal of internal medicine

authors： Legrand A,Pujol C,Durand CM,Mesnil A,Rubera I,Duranton C,Zuily S,Sousa AB,Renaud M,Boucher JL,Pietrancosta N,Adham S,Orssaud C,Marelli C,Casali C,Ziccardi L,Villain N,Ewenczyk C,Durr A,Mignot C,Stevanin G,Billon

更新日期：2020-10-27 00:00:00

abstract：:Cardiac troponin assays have become more sensitive over the years leading to the clinical introduction of high-sensitivity cardiac troponin assays in 2010. Their use has revolutionized the assessment of patients with chest pain in the emergency department by allowing earlier rule-in and rule-out of myocardial infarcti...

journal_title：Journal of internal medicine

authors： Holzmann MJ

更新日期：2018-07-01 00:00:00

abstract：:We investigated skeletal involvement in five male and two female patients with ochronosis, aged 26-82 years. The main parameters of mineral metabolism, together with biochemical markers of bone resorption (urinary N-telopeptides of type I collagen) and formation (serum bone isoenzyme of alkaline phosphatase and serum ...

journal_title：Journal of internal medicine

authors： Aliberti G,Pulignano I,Schiappoli A,Minisola S,Romagnoli E,Proietta M

更新日期：2003-09-01 00:00:00

abstract：STUDY OBJECTIVES:Asthma and gastro-oesophageal reflux (GER) are both characterized by airway inflammation. DESIGN:The purposes of this work were (i) to study airway inflammation in patients troubled by gastro-oesophageal reflux (GER) and GER associated with asthma, (ii) to ascertain whether GER can aggravate asthma by...

journal_title：Journal of internal medicine

authors： Carpagnano GE,Resta O,Ventura MT,Amoruso AC,Di Gioia G,Giliberti T,Refolo L,Foschino-Barbaro MP

更新日期：2006-03-01 00:00:00

abstract：:The success of antiretroviral therapy in treating HIV infection has greatly prolonged life expectancy in affected individuals, transforming the disease into a chronic condition. A number of HIV-associated non-AIDS comorbidities have emerged in the ageing HIV-infected population, including osteoporosis and increased ri...

journal_title：Journal of internal medicine

authors： Compston J

更新日期：2016-10-01 00:00:00

abstract：:Type 2 diabetes (T2DM) is a rapidly growing public health problem. It is associated with an increased risk of fracture, particularly of the hip, despite normal or high bone mineral density. Longer duration of disease and poor glycaemic control are both associated with higher fracture risk. The factors underlying incre...

journal_title：Journal of internal medicine

authors： Compston J

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:To study serum homocysteine concentration for its prediction of major coronary heart disease events amongst women. DESIGN:A case-control study nested within a follow-up study. Subjects. A total of 74 and 75 major coronary events (coronary deaths or nonfatal myocardial infarction) which occurred in women wit...

journal_title：Journal of internal medicine

authors： Knekt P,Alfthan G,Aromaa A,Heliövaara M,Marniemi J,Rissanen H,Reunanen A

更新日期：2001-05-01 00:00:00

abstract：:In the mitochondrion, inherited defects have been identified in the electron transport system by which ATP is formed, as well as in the transport and metabolism of fuels. Clinical findings in diseases due to these defects can be related to abnormal accumulations of metabolic intermediates and inadequate or inefficient...

journal_title：Journal of internal medicine

authors： Luft R,Landau BR

更新日期：1995-11-01 00:00:00

abstract：:Here, the notion of distributive justice is explored in relation to the introduction and the application of new medical technologies within the clinical setting. The point of departure is that, in the decision making process on what is necessary and fair in patient care, participants will mobilize different ethical mo...

journal_title：Journal of internal medicine

authors： van der Kloot Meijburg HH

更新日期：1995-12-01 00:00:00

abstract：:Hepatitis C virus infection is now one of the most important causes of chronic liver disease. Primary care physicians play an important role in the diagnosis and initial work-up of patients infected with this virus. Understanding which patients may be at risk is the first step. By understanding the correct use of hepa...

journal_title：Journal of internal medicine

authors： Larson AM,Carithers RL

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:To assess the relationships between circulating levels of proinflammatory cytokines and adrenocortical hormones and leptin early after stroke. DESIGN:Blood samples were collected four times daily the first two days after stroke, twice daily the next 4 days and four times at day 7. Cognitive function and func...

journal_title：Journal of internal medicine

authors： Johansson A,Ahrén B,Näsman B,Carlström K,Olsson T

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVES:To evaluate the concentrations of magnesium (Mg), potassium (K) and sodium,potassium pumps (Na,K pumps) in skeletal muscle in patients with chronic obstructive lung disease (COLD) treated with or without diuretics. DESIGN:An open cross-sectional study. SETTING:COLD patients admitted to the Medical Departme...

journal_title：Journal of internal medicine

authors： Ravn HB,Dørup I

更新日期：1997-01-01 00:00:00

abstract：:Interleukin-7 (IL-7) is required for the development and survival of T cells and plays a critical role in modulating T-cell homeostasis. This review will address current understanding of IL-7 biology, review recent clinical experiences and discuss potential future clinical applications of IL-7, or IL-7 blockade, in th...

journal_title：Journal of internal medicine

authors： Capitini CM,Chisti AA,Mackall CL

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:To describe types of diabetes treatment in a total, adult population, including those on no antidiabetic medication, and to evaluate use of the defined daily doses in estimation of diabetes prevalence. DESIGN:Cross-sectional epidemiologic survey applying patient-based questionnaires and clinical examination...

journal_title：Journal of internal medicine

authors： Midthjell K,Holmen J,Bjørndal A

更新日期：1994-09-01 00:00:00

abstract：:For nearly a decade since the mapping of the multiple endocrine neoplasia type 1 (MEN1) locus to 11q13 and the suggestion that it is a tumour suppressor gene, efforts have been made to identify the gene responsible for this familial cancer syndrome. Recently, we have identified the MEN1 gene by the positional cloning ...

journal_title：Journal of internal medicine

authors： Guru SC,Manickam P,Crabtree JS,Olufemi SE,Agarwal SK,Debelenko LV

更新日期：1998-06-01 00:00:00

abstract：:Multiple sclerosis (MS), a chronic inflammatory demyelinating and neurodegenerative disease of the central nervous system, is today a leading cause of unpredictable lifelong disability in young adults. The treatment of patients in progressive stages remains highly challenging, alluding to our limited understanding of ...

journal_title：Journal of internal medicine

authors： Kular L,Jagodic M

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:To analyse and evaluate current practice of asthma therapy by use of computerized prescription data. DESIGN:Descriptive, non-interventive. SETTING:A pharmacoepidemiological database on computerized refund claims from pharmacies in the Odense region in Denmark. SUBJECTS:Persons aged 20-44, presenting presc...

journal_title：Journal of internal medicine

authors： Hallas J,Hansen NC

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the frequency of the common Finnish and Norwegian mutations in the low density lipoprotein (LDL) receptor gene in Swedish patients with familial hypercholesterolaemia (FH), and to start screening for other mutations in these patients. In contrast to the situation in Norway and Finland, where the f...

journal_title：Journal of internal medicine

authors： Lind S,Eriksson M,Rystedt E,Wiklund O,Angelin B,Eggertsen G

更新日期：1998-07-01 00:00:00