Neural correlates of post-error slowing during a stop signal task: a functional magnetic resonance imaging study.

Abstract:

:The ability to detect errors and adjust behavior accordingly is essential for maneuvering in an uncertain environment. Errors are particularly prone to occur when multiple, conflicting responses are registered in a situation that requires flexible behavioral outputs; for instance, when a go signal requires a response and a stop signal requires inhibition of the response during a stop signal task (SST). Previous studies employing the SST have provided ample evidence indicating the importance of the medial cortical brain regions in conflict/error processing. Other studies have also related these regional activations to postconflict/error behavioral adjustment. However, very few studies have directly explored the neural correlates of postconflict/error behavioral adjustment. Here we employed an SST to elicit errors in approximately half of the stop trials despite constant behavioral adjustment of the observers. Using functional magnetic resonance imaging, we showed that prefrontal loci including the ventrolateral prefrontal cortex are involved in post-error slowing in reaction time. These results delineate the neural circuitry specifically involved in error-associated behavioral modifications.

journal_name

J Cogn Neurosci

authors

Li CS,Huang C,Yan P,Paliwal P,Constable RT,Sinha R

doi

10.1162/jocn.2008.20071

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

1021-9

issue

6

eissn

0898-929X

issn

1530-8898

journal_volume

20

pub_type

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