Unusual coexistence of bilateral keratoconus and optic disc pit: a case report.

Abstract:

PURPOSE:To report the unknown coexistence of bilateral optic disc pit and keratoconus. METHODS:A 23-year-old man with bilateral keratoconus underwent complete ophthalmology screening, with an unexpected detection of undiagnosed optic disc pit in both eyes. Computerized corneal topography (CT), Orbscan, corneal pachometry, endothelial microscopy, and optical coherence tomography (OCT) examination were performed. RESULTS:The corneal CT showed a keratoconus pattern in both eyes, evolved in the right eye with a minimum corneal pachometry of 336 micronm in the right eye and 405 micronm in the left eye. Mean endothelial cell density was 1937 cells/mm2 in the right eye and 1912 cells/mm2 in the left eye. The OCT scans showed the presence of the disc pit in both eyes with a normal macular thickness and profile in the right eye, and in the left eye an augmented retinal thickness in the nasal macular zone due to retinal oedema and schisis, with an initial detachment of the neuroepithelium in the parapapillary area starting from the optic pit. CONCLUSIONS:This is the first clinical report of bilateral optic disc pit and keratoconus. Further investigations will be necessary to assess if there is a possible pathogenetic correlation between these two ocular pathologies or if this is an unusual coexistence of separate entities.

journal_name

Eur J Ophthalmol

authors

Fasciani R,Mosca L,Giannico ML,Legrottaglie EF,Balestrazzi E

doi

10.1177/112067210801800124

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

134-7

issue

1

eissn

1120-6721

issn

1724-6016

journal_volume

18

pub_type

杂志文章
  • Achieving low target intraocular pressures in severe glaucoma.

    abstract:PURPOSE:This study aimed to assess details of therapy required to achieve an intraocular pressure (IOP) of ⩽12 mmHg in patients with severe glaucoma of different etiologies. METHODS:Patients with a follow-up of at least 1 year, who fulfilled inclusion criteria were selected, and data analyzed with respect to baseline ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120979903

    authors: Warjri GB,Sidhu T,Kishan A,Behera AK,Shakrawal J,Selvan H,Dada T,Pandey V,Sihota R

    更新日期:2020-12-08 00:00:00

  • Evaluation of eye movements pattern during reading process in patients with glaucoma: a microperimeter study.

    abstract:PURPOSE:To assess eye movements pattern during reading process in patients with primary open-angle glaucoma (POAG) using a microperimeter. METHODS:Thirty-two patients with POAG at early and moderate stage, according to Glaucoma Staging System 2, and 34 healthy age- and sex-matched subjects were included in the study. ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000397

    authors: Cerulli A,Cesareo M,Ciuffoletti E,Montanaro ML,Mancino R,Mirisola C,Sorge R,Cedrone C,Nucci C,Cerulli L

    更新日期:2014-05-01 00:00:00

  • Negative correlation between retinal displacement and ganglion cell layer thickness changes in eyes with epiretinal membrane.

    abstract:PURPOSE:To examine retinal displacement after vitrectomy with internal limiting membrane peeling for epiretinal membrane treatment, and to determine the correlation between the extent of displacement and the ganglion cell layer thickness changes. METHODS:Thirty-nine consecutive patients were evaluated. Optical coheren...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119894887

    authors: Loiudice P,Pellegrini M,Montesel A,Nardi M,Peiretti E,De Cillà S,Posarelli C,Figus M,Casini G

    更新日期:2020-11-01 00:00:00

  • Systemic evaluation of patients with central serous chorioretinopathy: A case-control study.

    abstract:OBJECTIVE:To investigate the systemic associations of central serous chorioretinopathy (CSCR) with help of clinical and biochemical investigations. DESIGN:Case-control study. PARTICIPANTS:Eighty seven CSCR patients (case) and 82 Asian-Indian patients with primary non-traumatic rhegmatogenous retinal detachment (contr...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120975698

    authors: Kumawat D,Ravi AK,Sahay P,Alam T,Desai A,Kumar A

    更新日期:2020-11-25 00:00:00

  • Surgical repair of large cyclodialysis clefts.

    abstract:PURPOSE:To describe a new surgical technique to effectively close large (>180 degrees) cyclodialysis clefts. METHODS:Our method involves the use of procedures commonly associated with repair of retinal detachment and complex cataract extraction: phacoemulsification with placement of a capsular tension ring followed by...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000868

    authors: Gross JB,Davis GH,Bell NP,Feldman RM,Blieden LS

    更新日期:2017-05-11 00:00:00

  • Closed chamber thermometry and humidity measurements in normal and dry eye patients: a pilot study.

    abstract:PURPOSE:To verify the diagnostic value of closed chamber thermometry and humidity measurement in normal and dry eye patients. METHODS:In 20 patients (40 eyes) with dry eye and 20 normal sex- and age-matched controls (40 eyes), aged from 11 to 61 years (mean 37.52 yrs, standard deviation, (SD) 14.81) temperature was me...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210301300403

    authors: Singh G,Bhinder HS

    更新日期:2003-05-01 00:00:00

  • Late postoperative capsular block syndrome: a case series studied before and after Nd:YAG laser posterior capsulotomy.

    abstract:PURPOSE:To evaluate the clinical characteristics of the unusual late postoperative capsular block syndrome (CBS) and the effect of Nd:YAG laser posterior capsulotomy on visual acuity and refractive error as well as its possible complications. METHODS:In this retrospective cohort study, 12 eyes of 11 patients with late...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000507

    authors: Huerva V,Sánchez MC,Ascaso FJ,Soldevila J

    更新日期:2015-01-01 00:00:00

  • Graded superior oblique tendon suture lengthening: A novel procedure.

    abstract:PURPOSE:Literature regarding different superior oblique (SO) weakening procedures showed variable results. Here, we aim to evaluate the effect of a novel superior oblique tendon suture lengthening (SOSL) procedure on weakening of SO in patients with A-pattern exotropia associated with dissociated vertical deviation and...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120968726

    authors: Xia W,Wu L,Yao J,Wen W,Wang X,Jiang C,Li L,Zhao C

    更新日期:2020-11-11 00:00:00

  • Tear histamine and histaminase during the early (EPR) and late (LPR) phases of the allergic reaction and the effects of lodoxamide.

    abstract::The objectives of this study were two-fold: to identify tear histamine content and its relationship to changes in tear histaminase activity during the early (EPR) and late phases (LPR) of the allergic reaction induced by a conjunctival provocation test (CPT) and to evaluate the effects of lodoxamide on histamine relea...

    journal_title:European journal of ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Leonardi AA,Smith LM,Fregona IA,Salmaso M,Secchi AG

    更新日期:1996-04-01 00:00:00

  • Long-term visual outcomes of vitrectomy for cystoid macular edema due to nonischemic central retinal vein occlusion.

    abstract:PURPOSE:To report the long-term surgical outcome of vitrectomy for cystoid macular edema due to nonischemic central retinal vein occlusion (CRVO). METHODS:A retrospective chart review of 25 consecutive eyes (25 patients) with cystoid macular edema due to nonischemic CRVO treated with vitrectomy was performed. All pati...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210601600609

    authors: Furukawa M,Kumagai K,Ogino N,Uemura A,Larson E

    更新日期:2006-11-01 00:00:00

  • The role of mitomycin C and porcine extracellular matrix in phacotrabeculectomy.

    abstract:PURPOSE:To compare between mitomycin C alone, porcine extracellular matrix alone, and combined low dose mitomycin C with porcine extracellular matrix in term of efficacy and safety in phaco-trabeculectomy surgery. STUDY DESIGN:Prospective comparative. METHODS:Sixty eyes of 60 patients complaining of primary open angl...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120944339

    authors: Hamdi MM,Hamdi IM

    更新日期:2021-01-01 00:00:00

  • The measurement of bulbar hyperemia: challenges and pitfalls.

    abstract:PURPOSE:To review methods of assessing bulbar redness, particularly with respect to the practicality of comparing different rating systems. METHODS:The published literature was reviewed and discussed by a panel of experts and a narrative review prepared. RESULTS:Bulbar hyperemia is a common clinical sign and an impor...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.5301/ejo.5000626

    authors: Baudouin C,Barton K,Cucherat M,Traverso C

    更新日期:2015-07-01 00:00:00

  • Capsular bag performance of a novel hydrophobic acrylic single-piece intraocular lens: Two-year results of a randomised controlled trial.

    abstract:PURPOSE:To determine the visual outcome, intraocular lens (IOL) stability and posterior capsule opacification (PCO) rate of a hydrophobic acrylic intraocular lens. SETTING:Vienna Institute for Research in Ocular Surgery, Hanusch Hospital, Vienna, Austria. DESIGN:This double-masked randomised study included patients w...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120960591

    authors: Fișuș AD,Hirnschall ND,Maedel S,Fichtenbaum M,Draschl P,Findl O

    更新日期:2020-09-29 00:00:00

  • Diabetic retinopathy and cerebral hemodynamic impairment in type II diabetes.

    abstract:PURPOSE:To assess whether a screening method based on transcranial Doppler (TCD) examination could detect signs of brain hemodynamic impairment in non-insulin-dependent diabetic patients with retinal microangiopathy of varying severity, asymptomatic for cerebrovascular diseases. METHODS:We studied 86 patients stratifi...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Lippera S,Gregorio F,Ceravolo MG,Lagalla G,Provinciali L

    更新日期:1997-04-01 00:00:00

  • Visual performance and patient satisfaction following the implantation of a novel trifocal supplementary intraocular lens.

    abstract:PURPOSE:To evaluate the visual quality, visual performance, and patient satisfaction after the implantation of the last generation supplementary intraocular lens (1stQ AddOn Trifocal) for achieving near vision spectacle-independence in pseudophakic patients who had primary monofocal capsular bag implantation. METHODS:...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120969042

    authors: Albayrak S,Comba ÖB,Karakaya M

    更新日期:2020-11-06 00:00:00

  • Ophthalmologic findings in fifteen patients with Wolfram syndrome.

    abstract:PURPOSE:To look for ophthalmologic abnormalities in 15 patients with Wolfram syndrome, also known as DIDMOAD syndrome (diabetes insipidus, diabetes mellitus, optic atrophy and deafness). METHODS:Fifteen patients from four inbred families diagnosed as having Wolfram syndrome at the National Center for Diabetes, Endocri...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210201200202

    authors: Al-Till M,Jarrah NS,Ajlouni KM

    更新日期:2002-03-01 00:00:00

  • A new parameter for assessing the thickness of the retinal nerve fiber layer for glaucoma diagnosis.

    abstract:PURPOSE:To investigate a new method for assessing the thickness of the retinal nerve fiber layer thickness (NFLT) for glaucoma diagnosis, using scanning laser polarimetry. MATERIAL AND METHODS:Thirty eyes of thirty patients with ocular hypertension or glaucoma were examined using a scanning laser polarimeter. NFL T wa...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067219900900204

    authors: Kogure S,Iijima H,Tsukahara S

    更新日期:1999-04-01 00:00:00

  • A pilot study of the use of objective structural clinical examinations for the assessment of ophthalmology education.

    abstract:PURPOSE:A pilot study was carried out to evaluate the practicality, reliability, and validity of an objective structured clinical examination (OSCE) for assessing the clinical skills and abilities of specialists in ophthalmology. METHODS:Ten unfolded OSCE style, criterion referenced questions were asked to nine candid...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210601600415

    authors: Aydin P,Gunalp I,Hasanreisoglu B,Unal M,Erol Turacli M

    更新日期:2006-07-01 00:00:00

  • Dominant optic atrophy in a Japanese family with OPA1 frameshift mutation (V942fsX966).

    abstract:PURPOSE:The authors report the ophthalmic characteristics of a male proband in a Japanese family with autosomal dominant optic atrophy (DOA) harboring a frameshift mutation in the OPA1 gene. METHODS:Conventional ophthalmologic examinations including static automated perimetry were performed, as well as assessment of t...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210701700216

    authors: Hayashi T,Takeuchi T,Gekka T,Kitahara K

    更新日期:2007-03-01 00:00:00

  • Definition of indicators of appropriateness in the management of neovascular age-related macular degeneration: An expert opinion.

    abstract::Wet age-related macular degeneration is a chronic condition culminating, in most cases, in blindness. The introduction of anti-angiogenic agents in 2006 has represented a major breakthrough in the treatment of the disease, but timely and effective treatment with regular follow-up and monitoring is mandatory to stabili...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1177/1120672120915685

    authors: Avitabile T,Boscia F,Dell'Erba A,Introini U,Lanzetta P,Locatelli P,Ricci F,Staurenghi G,Varano M,Zotti F

    更新日期:2020-07-01 00:00:00

  • Risk factors for intraoperative and early postoperative complications in extracapsular cataract surgery.

    abstract::The risk factors for intraoperative and early postoperative complications were evaluated in 351 consecutive cataract operations at the Oulu University Hospital in 1990. Bleeding into the anterior chamber during the operation was recorded in 8.6%, zonular rupture in 6.6%, posterior capsular rupture in 5.4% and vitreous...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Lumme P,Laatikainen LT

    更新日期:1994-07-01 00:00:00

  • Unilateral optic atrophy preceding Coats disease in a girl with Parry-Romberg syndrome.

    abstract:PURPOSE:Parry-Romberg syndrome (PRS) is a rare disease of unknown etiology and pathogenesis, characterized by progressive hemifacial atrophy. Diverse ocular manifestations were reported in association with PRS, including enophthalmos, lid retraction, blepharoptosis, restrictive strabismus, ocular motor nerve dysfunctio...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067211002000132

    authors: Nasser O,Greiner K,Amer R

    更新日期:2010-01-01 00:00:00

  • Fluorescein angiography--is it safe to use in a pregnant patient?

    abstract::We sent questionnaires to 424 retina specialists in order to compile information on the use of fluorescein angiography in pregnant women. Four-hundred and three specialists responded. Of these, 313 (78%) had never performed fluorescein angiography on a pregnant woman. Ninety specialists (22%) had performed at least on...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Olk RJ,Halperin LS,Soubrane G,Coscas G

    更新日期:1991-04-01 00:00:00

  • Five-year results of viscotrabeculotomy versus conventional trabeculotomy in primary congenital glaucoma: A randomized controlled study.

    abstract:PURPOSE:To assess the long-term results of viscotrabeculotomy in infants with primary congenital glaucoma and to compare its outcome with conventional trabeculotomy. PATIENTS AND METHODS:A prospective randomized comparative study included infants with primary congenital glaucoma younger than 2 years. Patients were div...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120922453

    authors: Elwehidy AS,Hagras SM,Bayoumi N,AbdelGhafar AE,Badawi AE

    更新日期:2020-05-26 00:00:00

  • Upregulation of ICAM-1 expression in the conjunctiva of patients with chronic graft-versus-host disease.

    abstract:PURPOSE:To correlate conjunctival intercellular adhesion molecule 1 (ICAM-1) expression with cytologic and clinical findings of chronic graft-versus-host disease (GVHD). METHODS:Seven patients with chronic GVHD-related keratoconjunctivitis and five age-matched normal controls were recruited for the study. Clinical exa...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210601600104

    authors: Aronni S,Cortes M,Sacchetti M,Lambiase A,Micera A,Sgrulletta R,Bonini S

    更新日期:2006-01-01 00:00:00

  • Incidence and quantitative analysis of dissociated optic nerve fiber layer appearance: real loss of retinal nerve fiber layer?

    abstract:PURPOSE:To assess the association between appearance of dissociated optic nerve fiber layer (DONFL) after internal limiting membrane (ILM) peeling and changes in the macular nerve fiber layer (NFL) area by spectral-domain optical coherence tomography (SD-OCT). METHODS:This study included 132 consecutive patients who h...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5001067

    authors: Kim YJ,Lee KS,Joe SG,Kim JG

    更新日期:2018-05-01 00:00:00

  • Unusual presentation of Retinoblastoma.

    abstract::Most cases of retinoblastoma are diagnosed before the age of 5 years. The cases in older age groups can have variable presentations leading to misdiagnosis and management challenges. We report a case of retinoblastoma in an 8-year-old female who was primarily referred as a case of sympathetic ophthalmia due to a co-in...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120939388

    authors: Narang S,Sindhu M,Jinagal J,Handa U,Kochhar S

    更新日期:2020-07-02 00:00:00

  • Non-invasive measurement techniques for quantitative assessment of optic nerve head blood flow.

    abstract::Diseases of the optic nerve head involving changes in blood flow are common. However, the pathophysiology is not always fully understood. Several non-invasive methods for measuring optic nerve head blood flow are available, but currently no gold standard has been established. Methods for measuring blood flow in optic ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1177/1120672119858891

    authors: Vosborg F,Malmqvist L,Hamann S

    更新日期:2020-03-01 00:00:00

  • Retained lens fragments: nucleus fragments are associated with worse prognosis than cortex or epinucleus fragments.

    abstract:PURPOSE:To identify factors that determined the outcome of eyes that underwent pars plana vitrectomy for retained lens fragments after phacoemulsification. METHODS:A retrospective review of the records of 63 eyes that underwent vitrectomy for retained lens fragments after phacoemulsification. Fragments were defined as...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2011.6483

    authors: Moisseiev E,Kinori M,Glovinsky Y,Loewenstein A,Moisseiev J,Barak A

    更新日期:2011-11-01 00:00:00

  • Is there alteration in aortic stiffness in Leber hereditary optic neuropathy?

    abstract:PURPOSE:Leber hereditary optic neuropathy (LHON) is recognized as the most common cause of isolated blindness in young men. The current study was designed to test whether LHON as a mitochondrial disease is associated with vascular functional alterations characterized by aortic elastic properties during echocardiography...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210801800225

    authors: Nemes A,De Coo IF,Spruijt L,Smeets HJ,Chinnery PF,Soliman OI,Geleijnse ML,Ten Cate FJ

    更新日期:2008-03-01 00:00:00