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Prevalence of significant QTc prolongation and long QT syndrome in adolescents with syncope.

Abstract：

:A total of 664 high school students having >or=1 episode of syncope and 560 students without syncope (controls) underwent 12-lead ECG. A significant QT prolongation was defined as corrected QT (QTc)>470 ms in male and >480 ms in female. A diagnosis of LQTS was made by Schwartz's score. Most students had only 1 episode of syncope (66.1%), 2 (16.9%), 3 (11.6%), and >or=4 (5.4%). Most syncopal episodes were related to non-exertional events with only 11.4% related to exertion. The QTc distribution of the study group was almost identical to controls with mean QTc of 405.1+/-23.2 vs 402.5+/-23.4 ms, respectively. Only one male (0.15%) in the study group had significant QTc prolongation. None met the criteria for diagnosis of LQTS (score>or=4). In conclusion, the prevalence of LQTS in adolescents having syncope seems to be low in this cohort study.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Khositseth A,Wattanasirichaigoon D,Ruangkanchanasetr S

doi

10.1016/j.ijcard.2007.07.102

subject

Has Abstract

pub_date

2009-01-24 00:00:00

pages

405-7

issue

3

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(07)01680-4

journal_volume

131

pub_type

信件

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