Abstract:
:Chronic sickle cell (SC) disease is known to cause pulmonary hypertension (PH) which eventually affects right as well as left ventricular function. However, the acute effects of SC crisis on right ventricular (RV) function in adults have not been well described. Our echocardiography database was queried for patients followed in the outpatient hematology clinic, who were admitted with SC crises, and had an inpatient echocardiogram. Comparisons of RV fractional area change (RVFAC) and tricuspid annular peak systolic excursion (TAPSE) were then made to a group of healthy patients and a group with mild PH. TAPSE was normal in patients with SC disease (3.05+/-0.56). However, the SC patients had significantly larger RV's compared to controls and mild PH patients (31.33+/-7.23 cm(2) vs. 19.07+/-4.49 cm(2) and 21.51+/-6.07 cm(2), respectively, P<0.0001). RVFAC was reduced in SC patients, and was comparable to patients with mild PH (46+/-9% vs. 49 +/-14%, P=0.4). We found no correlation between hemoglobin level (8.1+/-2.5 g) and RVFAC, TAPSE, or PH severity. We found that adult patients admitted with SC crises have frequent dilatation of the RV with an abnormal reduction in RVFAC, despite normal TAPSE values. Therefore, caution should be exercised in using TAPSE to estimate RV function in this patient population.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Ramani GV,Edelman K,López-Candales Adoi
10.1016/j.ijcard.2007.08.099subject
Has Abstractpub_date
2009-03-06 00:00:00pages
448-50issue
3eissn
0167-5273issn
1874-1754pii
S0167-5273(07)01870-0journal_volume
132pub_type
信件abstract:AIM:In 2002 the ACC/AHA guidelines for the management of patients with unstable angina (UA) and non-ST-segment elevation myocardial infarction (NSTEMI) were updated. We aimed to answer whether the implementation of updated guidelines was capable of influencing short- and long-term mortality in these patients. METHODS:...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2011.02.073
更新日期:2012-09-06 00:00:00
abstract:BACKGROUND:Friedreich ataxia is an autosomal recessive neurodegenerative disorder characterized by ataxia of all four limbs, dysarthria, areflexia, and cardiomyopathy. At present, baseline values of cardiac troponin I are unknown among Friedreich ataxia subjects. METHODS:In this study, we evaluated baseline plasma car...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2012.04.159
更新日期:2013-08-20 00:00:00
abstract:BACKGROUND:Lower serum chloride (Cl) is associated with mortality in heart failure patients and may be more prognostically relevant than sodium. However, the association of hemodynamics and Cl levels is unknown. METHODS:438 sequential patients with advanced chronic heart failure (ACHF) underwent invasive hemodynamic a...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.11.024
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The management of heart disease in pregnancy is highly specialized. Guidelines are based on observational studies. This paper describes our experience of these patients, including adverse cardiac events, adherence to guidelines, and areas of suboptimal management. METHODS:Patients referred to the service be...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2007.11.084
更新日期:2009-03-20 00:00:00
abstract:BACKGROUND:We investigated preferences of adults with congenital heart disease (CHD) and their health care providers regarding end-of-life (EOL) communication. METHODS:Adult CHD outpatients and health care providers completed surveys about preferences for and experiences with EOL communication. Responses were compared...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2010.10.050
更新日期:2012-03-22 00:00:00
abstract:BACKGROUND:Low-frequency heart rate variability (LF-HRV) at rest has already been successfully modeled as self-sustained oscillations in a nonlinear control loop, but these models fail to simulate LF-HRV decreases either during aerobic exercise or in heart failure patients. Following control engineering practices, we a...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2012.09.073
更新日期:2013-09-20 00:00:00
abstract::Although increasing hypertension rates have been reported in several African populations, little is known about the frequency of resulting hypertensive complications in these populations. We recorded the electrocardiograms of 482 male and 284 female civil servants in Benin City, Nigeria. Five different criteria were u...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(99)00061-3
更新日期:1999-07-01 00:00:00
abstract::This report presents a 60-year-old female who had acute anteroseptal myocardial infarction and a grade 3/6 pansystolic murmur at left lower sternal border. Color Doppler echocardiographic examination revealed the presence of a ventricular septal defect which was later confirmed by contrast left ventriculography and at...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(91)90276-u
更新日期:1991-04-01 00:00:00
abstract:BACKGROUND:Effective decongestion of heart failure patients predicts improved outcomes, but high dose loop diuretics (HDLD) used to achieve diuresis predict adverse outcomes. In the DOSE trial, randomization to a HDLD intensification strategy (HDLD-strategy) improved diuresis but not outcomes. Our objective was to dete...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ijcard.2017.03.114
更新日期:2017-08-15 00:00:00
abstract:BACKGROUND:Exercise capacity following Fontan surgery is often depressed. An inability to reduce pulmonary vascular resistance appropriately during exercise may contribute to this phenomenon. The aim of this study was to determine whether administration of iloprost, a selective pulmonary vasodilator, would improve exer...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2013.03.014
更新日期:2013-10-03 00:00:00
abstract::Cardiovascular morbidity and mortality in patients with type 2 diabetes are a major problem in clinical practice. Thiazolidinediones (TZDs) are agonists of the peroxisome proliferator-activated receptor gamma which improve glycaemic control by reducing insulin resistance. TZDs also seem to have beneficial effects on v...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2008.06.005
更新日期:2009-01-24 00:00:00
abstract:INTRODUCTION:Corticosteroid administration in Kawasaki disease (KD) is controversial but accepted as treatment for patients who do not respond to initial treatment. The impact of corticosteroids on evolving coronary artery aneurysms (CAA) and future vascular remodelling is unknown. METHODS AND RESULTS:The clinical his...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2010.08.070
更新日期:2012-01-12 00:00:00
abstract::Time-frequency maps of signal-averaged electrocardiogram based on a short time Fourier transform (STFT) technique analysis was employed to assess the presence of high frequency electrical transients (turbulence) and arrhythmia risk assessment. The optimal configuration set of STFT variables aiming at risk stratificati...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2009.04.013
更新日期:2010-11-05 00:00:00
abstract:BACKGROUND:Periodontitis (PD) and type 2 diabetes (T2D) are characterized by increased mitochondrial oxidative stress production (mtROS), which has been associated with a greater risk of cardiovascular diseases (CVD). Intensive PD treatment (IPT) can significantly improve endothelial function and metabolic control, alt...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2018.05.019
更新日期:2018-11-15 00:00:00
abstract:BACKGROUND:Since the body of evidence addressing the coagulation derangements caused by Coronavirus disease (COVID-19) has been constantly growing, we investigated whether pre-hospitalization oral anticoagulation (OAC) or in-hospital heparin treatment could have a protective role among COVID-19 patients. METHOD:In thi...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2020.09.001
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND:Since its first description in 1991, many cases of transient left ventricular apical ballooning syndrome (TLVABS) have been described, but the use of cardiac MRI in this condition is much more recent. METHODS AND RESULTS:We performed a systematic review of the present literature in the MEDLINE and EMBASE da...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2009.03.067
更新日期:2009-06-26 00:00:00
abstract:BACKGROUND:Geranylgeranylacetone (GGA) has been reported up-regulating heat shock protein (HSP) expression, and protecting against atrial remodeling. This study aimed to investigate the effects of GGA on atrial electrophysiology and inducibility of atrial fibrillation (AF) in heart failure (HF) model. METHODS AND RESU...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2013.06.072
更新日期:2013-10-09 00:00:00
abstract:BACKGROUND:Studies in patients support a beneficial effect of statin treatment early after acute coronary syndrome and/or prior percutaneous coronary intervention. However, statin effect during total occlusion remains unknown. OBJECTIVES:To investigate whether infusion of activated simvastatin during ischemia and prio...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2014.06.040
更新日期:2014-08-20 00:00:00
abstract::We report a rare case of torsade de pointes, a polymorphic ventricular tachycardia associated with QT interval prolongation, caused by intravenous ciprofloxacin given for pneumonia in a 22-year-old healthy Marine. Although the risk for quinolone-associated torsade de pointes appears to be low, caution is still warrant...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2005.08.048
更新日期:2006-11-10 00:00:00
abstract::Large multi-center clinical trials have indicated significant clinical benefits for patients with atherosclerotic vascular diseases receiving clopidogrel therapy. Clopidogrel efficacy has been proven in cardiac and extracardiac vascular diseases. Thus, the popularity of using clopidogrel is likely to increase in the n...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.05.058
更新日期:2007-05-02 00:00:00
abstract::Mycobacterium tuberculosis (TB) is a major cause of death globally. TB is capable of infecting every organ in the body, and the heart is no exception. Tuberculous endocarditis (TBE) was first reported in 1892 and subsequently many other cases have been described, highlighting the significant morbidity and mortality as...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2012.08.009
更新日期:2013-08-10 00:00:00
abstract::A 44-year-old woman with hypertension was admitted because of recent onset chest pain. Coronary angiography revealed an anomalous right coronary artery originating as a separate branch from the left anterior descending artery. Associated with the present case all published case reports were thoroughly investigated and...
journal_title:International journal of cardiology
pub_type: 信件,评审
doi:10.1016/j.ijcard.2007.04.121
更新日期:2008-07-04 00:00:00
abstract:BACKGROUND:Patients with syncope or near syncope of unknown etiology represent a great challenge to cardiologists. An initial symptomatic episode triggers a series of diagnostic analysis which remain unsatisfactory when negative. More invasive tools such as electrophysiologic testing yield only partial answers to risk ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.05.025
更新日期:2006-04-28 00:00:00
abstract::An analysis of 6 patients with overriding atrioventricular valve was performed in order to correlate the anatomic and angiographic features of this malformation. The atrial arrangement was usual (situs solitus) in each patient. The ventricular chambers were normally related in 4 and the mirror image of normal in 2. Th...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(85)90031-2
更新日期:1985-11-01 00:00:00
abstract:BACKGROUND:It is unclear whether the cardiac mitochondrial dependent apoptotic pathways and Fas death receptor dependent apoptotic pathways will be induced by long-term intermittent hypoxia. METHODS:Twenty-seven Sprague-Dawley rats were randomly assigned into three groups: normoxia, long-term intermittent hypoxia (12%...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2006.03.064
更新日期:2007-04-04 00:00:00
abstract::The response over time of the QT interval and the Transmural Dispersion of Repolarization (TDR) to Isoproterenol infusion (ISO) in an 85 year-old-man with severe and syntomatic bradycardia, in the setting of an Amiodarone-induced Long QT Syndrome (LQTS) is the subject of this communication. ISO shortened the QT and de...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.07.175
更新日期:2009-04-17 00:00:00
abstract:BACKGROUND:While only few data exist correlating cardiovascular risk factors with volumetric measurements of coronary atheroma burden in patients with coronary artery disease, a recent report using intravascular ultrasound (IVUS) demonstrated independent predictors of atherosclerotic burden in a native coronary artery ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.11.194
更新日期:2008-02-20 00:00:00
abstract:BACKGROUND:Hematologic abnormalities such as elevated red blood cell distribution width (RDW) as well as anemia are prognostically meaningful among heart failure (HF) patients. The inter-relationship between these hematologic abnormalities in HF is unclear, however. We therefore aimed to assess whether RDW is predictin...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2011.04.018
更新日期:2012-10-18 00:00:00
abstract::In this study, the effect of celiprolol (beta-1-antagonist with beta-2-agonistic activity) on hemodynamic and electrocardiographic parameters of patients with congestive heart failure due to ischemic (iCMP) and non-ischemic (niCMP) origin should be evaluated. Sixteen patients were included into the study, nine with iC...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
doi:10.1016/s0167-5273(98)00377-5
更新日期:1999-03-15 00:00:00
abstract::Constrictive pericarditis has been defined classically as a progressive condition, characterized by pericardial fibrosis, with or without calcification, which results in chronic refractory congestive heart failure and for witch pericardiectomy is often required. In the last decades there have been reports describing a...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.05.097
更新日期:2009-01-09 00:00:00