Etiology of the dimensions of anxiety sensitivity: a behavioral-genetic analysis.

Abstract:

:Evidence suggests that anxiety sensitivity (AS) contributes to individual differences in fearfulness and to the risk of developing anxiety disorders. To investigate the origins of AS we administered the Anxiety Sensitivity Index to 245 monozygotic and 193 dizygotic twin pairs, comprising 658 women and 218 men. Scores were calculated for the most widely replicated AS dimensions; physical, cognitive, and social concerns. For women, each dimension was influenced by a combination of genetic and environmental factors. Heritability in women significantly increased with AS scores, indicating that severe forms of AS, compared to milder forms, are more strongly influenced by genetic factors. Correlations among AS dimensions for women could be explained by genetic and environmental factors influencing all three dimensions. For men, dimensions were influenced by environmental but not genetic factors. Correlations among dimensions for men could be explained by environmental factors influencing all dimensions. Overall, the findings reveal that AS has more complex etiology than previously recognized; its dimensions appear to arise from a mix of dimension-specific and non-specific etiologic factors, whose importance vary as a function of sex and severity.

journal_name

J Anxiety Disord

authors

Taylor S,Jang KL,Stewart SH,Stein MB

doi

10.1016/j.janxdis.2007.09.005

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

899-914

issue

5

eissn

0887-6185

issn

1873-7897

pii

S0887-6185(07)00175-2

journal_volume

22

pub_type

杂志文章
  • The physical health consequences of PTSD and PTSD symptoms: a meta-analytic review.

    abstract::The present meta-analysis systematically examined associations between physical health and posttraumatic stress disorder (PTSD)/PTSD symptoms (PTSS), as well as moderators of this relationship. Literature searches yielded 62 studies examining the impact of PTSD/PTSS on physical health-related quality of life (HR-QOL),...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.janxdis.2012.08.004

    authors: Pacella ML,Hruska B,Delahanty DL

    更新日期:2013-01-01 00:00:00

  • Family distress and involvement in relatives of obsessive-compulsive disorder patients.

    abstract::Obsessive compulsive disorder (OCD) affects the lives of patients as well as their relatives. Calvocoressi et al. (1995) suggested that accommodation (e.g., participating in the patient's rituals) by relatives of patients with OCD was related to global family dysfunction and distress. These investigators did not, howe...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/s0887-6185(99)00032-8

    authors: Amir N,Freshman M,Foa EB

    更新日期:2000-05-01 00:00:00

  • Obsessive beliefs in first-degree relatives of patients with OCD: a test of the cognitive vulnerability model.

    abstract::Cognitive models of obsessive-compulsive disorder (OCD) focus on the role of dysfunctional beliefs and appraisals in conferring risk to the onset and persistence of clinical obsessions. The origins of obsessive beliefs have been proposed to occur within a familial-based developmental context, although little research ...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2008.06.001

    authors: Rector NA,Cassin SE,Richter MA,Burroughs E

    更新日期:2009-01-01 00:00:00

  • Eye Movement Desensitization and Reprocessing (EMDR) and the anxiety disorders: clinical and research implications of an integrated psychotherapy treatment.

    abstract::Four recent, independent, rigorously controlled studies of Eye Movement Desensitization and Reprocessing (EMDR) have reported that 84 to 100% of single-trauma victims no longer maintain the posttraumatic stress disorder diagnosis after the equivalent of three 90-minute sessions. The rapidity of EMDR treatment effects ...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章,评审

    doi:10.1016/s0887-6185(98)00038-3

    authors: Shapiro F

    更新日期:1999-01-01 00:00:00

  • Climate anxiety: Psychological responses to climate change.

    abstract::Climate change will affect psychological wellbeing. Substantial research has documented harmful impacts on physical health, mental health, and social relations from exposure to extreme weather events that are associated with climate change. Recently, attention has turned to the possible effects of climate change on me...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2020.102263

    authors: Clayton S

    更新日期:2020-08-01 00:00:00

  • Disgust, anxiety, and vasovagal syncope sensations: a comparison of injection-fearful and nonfearful blood donors.

    abstract::Although research has implicated disgust in the fainting response observed in blood-injection-injury (BII) phobia, this finding has not been consistently observed in the literature. The present study further examines the relationship between disgust and fainting symptoms among injection-fearful (n=108) and nonfearful ...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2010.06.021

    authors: Viar MA,Etzel EN,Ciesielski BG,Olatunji BO

    更新日期:2010-12-01 00:00:00

  • Hypervigilance-avoidance pattern in spider phobia.

    abstract::Cognitive-motivational theories of phobias propose that patients' behavior is characterized by a hypervigilance-avoidance pattern. This implies that phobics initially direct their attention towards fear-relevant stimuli, followed by avoidance that is thought to prevent objective evaluation and habituation. However, pr...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2003.12.002

    authors: Pflugshaupt T,Mosimann UP,von Wartburg R,Schmitt W,Nyffeler T,Müri RM

    更新日期:2005-01-01 00:00:00

  • Lifetime trauma history and panic disorder: findings from the National Comorbidity Survey.

    abstract:OBJECTIVE:The purpose of this article is to examine prevalence of lifetime traumatic experiences in a community sample of panic disorder patients. METHOD:We examined trauma rates in a cohort of panic disorder patients. Also, we statistically disaggregated comorbid PTSD from individuals diagnosed with panic disorder in...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/s0887-6185(02)00125-1

    authors: Leskin GA,Sheikh JI

    更新日期:2002-01-01 00:00:00

  • Scrupulosity disorder: an overview and introductory analysis.

    abstract::Scrupulosity is a psychological disorder primarily characterized by pathological guilt or obsession associated with moral or religious issues that is often accompanied by compulsive moral or religious observance and is highly distressing and maladaptive. This paper provides a comprehensive overview of scrupulosity and...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章,评审

    doi:10.1016/j.janxdis.2007.11.004

    authors: Miller CH,Hedges DW

    更新日期:2008-08-01 00:00:00

  • The roles of anxiety and depression in connecting tic severity and functional impairment.

    abstract::The current study examined relationships between tic severity and both functional impairment and perceived quality of life (QOL) in adults with a chronic tic disorder. The authors explored whether these relationships were moderated by anxiety and depressive symptoms. Five-hundred adults with Tourette's Disorder, Chron...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2010.08.016

    authors: Lewin AB,Storch EA,Conelea CA,Woods DW,Zinner SH,Budman CL,Scahill LD,Compton SN,Walkup JT,Murphy TK

    更新日期:2011-03-01 00:00:00

  • Posttraumatic stress symptom clusters associations with psychopathology and functional impairment.

    abstract::We examined posttraumatic stress symptom clusters associations with psychopathology and functional impairment in 899 Norwegian survivors of the 2004 South-East Asia tsunami six months post-disaster. Posttraumatic stress symptoms were assessed with the Impact of Event Scale-Revised (IES-R) with intrusion, avoidance, an...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2010.06.020

    authors: Heir T,Piatigorsky A,Weisæth L

    更新日期:2010-12-01 00:00:00

  • The phenomenology of non-clinical panic in older adults in comparison to younger adults.

    abstract::The prevalence and nature of panic symptoms in the elderly are poorly understood. In a replication and extension of Deer and Calamari [J. Behav. Ther. Exp. Psychiatry 29 (1998) 303], the current study sought to determine which symptoms of anxiety best differentiated elderly endorsers of panic from elderly who do not p...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2004.04.007

    authors: Depp C,Woodruff-Borden J,Meeks S,Gretarsdottir E,DeKryger N

    更新日期:2005-01-01 00:00:00

  • Specificity of belief domains in OCD: validation of the French version of the Obsessive Beliefs Questionnaire and a comparison across samples.

    abstract::This paper assesses the psychometric properties of the French version of the Obsessive Beliefs Questionnaire (OBQ-44) and investigates whether the questionnaire discriminates between obsessive-compulsive disorder (OCD), anxious control (AC), and non-clinical control (NCC) participants. A confirmatory factor analysis s...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.janxdis.2007.11.003

    authors: Julien D,Careau Y,O'Connor KP,Bouvard M,Rhéaume J,Langlois F,Freeston MH,Radomsky AS,Cottraux J

    更新日期:2008-08-01 00:00:00

  • A community study of generalized anxiety disorder with vs. without health anxiety in Hong Kong.

    abstract:BACKGROUND:Although generalized anxiety disorder (GAD) is characterized by multiple worries, anxiety about one's health is absent in the DSM-IV description of the illness. METHOD:A random community-based telephone survey (N = 2005) that covered DSM-IV symptoms of GAD, two core symptoms of major depression, Rome-III cr...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2010.10.012

    authors: Lee S,Ma YL,Tsang A

    更新日期:2011-04-01 00:00:00

  • Cognitive-behavioral therapy for obsessive-compulsive disorder: a non-randomized comparison of intensive and weekly approaches.

    abstract::This study examined the relative efficacy of intensive versus weekly cognitive-behavioral therapy (CBT) for adults with obsessive-compulsive disorder (OCD). Sixty-two adults with OCD received either 14 sessions of weekly (n=30) or intensive CBT (n=32; daily psychotherapy sessions) in a non-randomized format. Assessmen...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2007.12.001

    authors: Storch EA,Merlo LJ,Lehmkuhl H,Geffken GR,Jacob M,Ricketts E,Murphy TK,Goodman WK

    更新日期:2008-10-01 00:00:00

  • Evaluating the role of panic disorder in emotional sensitivity processes involved with smoking.

    abstract::The present study investigated the relationship between panic disorder and emotional sensitivity processes related to smoking. Participants were 170 young adult (mean age = 25.2 [8.4]) regular smokers (mean cigarettes per day = 15.6 [2.4]) with (n = 69) and without (n = 101) a primary diagnosis of panic disorder. Cons...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.janxdis.2004.07.001

    authors: Zvolensky MJ,Schmidt NB,Antony MM,McCabe RE,Forsyth JP,Feldner MT,Leen-Feldner E,Karekla M,Kahler CW

    更新日期:2005-01-01 00:00:00

  • Comorbid posttraumatic stress disorder and major depressive disorder: The usefulness of a sequential treatment approach within a randomised design.

    abstract::Cognitive Processing Therapy (CPT) and Behavioural Activation Therapy (BA) were used to treat individuals with comorbid posttraumatic stress disorder (PTSD) and major depressive disorder (MDD). Fifty-two individuals (48 women, 4 men) were randomized to CPT alone (n = 18), CPT then BA for MDD (n = 17), or BA then CPT (...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2020.102324

    authors: Angelakis S,Weber N,Nixon RDV

    更新日期:2020-12-01 00:00:00

  • Enhanced Stroop interference for threat in social phobia.

    abstract::Socially anxious individuals are characterized by an attentional bias for threat-related information. However, this attentional bias to threat may be attenuated [Behav. Res. Ther. 34 (1996) 945] when these individuals are anxious. In the present study, we attempted to increase subjects' Stroop interference by changing...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/s0887-6185(01)00084-6

    authors: Ami N,Freshman M,Foa E

    更新日期:2002-01-01 00:00:00

  • Exposure to heights in a theme park: fear, dizziness, and body sway.

    abstract::Fear of heights results in the experience of dizziness and measurable body sway. We investigated the relationship between fear, dizziness, and body sway during height exposure 16 m above ground. Thirty five healthy participants stood on a force-plate to measure sway before, during, and after exposure and an ECG was re...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2007.05.008

    authors: Alpers GW,Adolph D

    更新日期:2008-05-01 00:00:00

  • Naltrexone renders one-session exposure therapy less effective: a controlled pilot study.

    abstract::In vivo exposure has become the gold standard treatment for specific phobia. The endogenous opioid system is one mechanism proposed to explain why exposure provides such quick and effective treatment for specific phobia. The effect of naltrexone on fear and avoidance behavior was investigated among 15 specific phobia ...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.janxdis.2006.03.011

    authors: Kozak AT,Spates CR,McChargue DE,Bailey KC,Schneider KL,Liepman MR

    更新日期:2007-01-01 00:00:00

  • Three decades of increase in health anxiety: Systematic review and meta-analysis of birth cohort changes in university student samples from 1985 to 2017.

    abstract::Health anxiety can be defined as a multifaceted trait that is primarily characterised by a fear of, or preoccupation with, serious illness. Whereas low levels of health anxiety can be helpful, clinically significant levels are associated with personal suffering and substantial societal costs. As general anxiety is pro...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.janxdis.2020.102208

    authors: Kosic A,Lindholm P,Järvholm K,Hedman-Lagerlöf E,Axelsson E

    更新日期:2020-04-01 00:00:00

  • Internet-assisted delivery of cognitive behavioural therapy (CBT) for childhood anxiety: systematic review and meta-analysis.

    abstract:AIM:To conduct a systematic review and meta-analysis of the literature to assess efficacy of internet-delivered cognitive behavioural therapy (CBT) for child anxiety disorder. METHOD:A systematic search of 7 electronic databases was conducted to assess CBT intervention for children with anxiety problems with remote de...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.janxdis.2014.11.006

    authors: Rooksby M,Elouafkaoui P,Humphris G,Clarkson J,Freeman R

    更新日期:2015-01-01 00:00:00

  • Self-medication of anxiety disorders with alcohol and drugs: Results from a nationally representative sample.

    abstract::Self-medication--the use of alcohol or drugs in an attempt to reduce anxiety--has often been invoked as an explanatory mechanism for the high co-occurrence of anxiety and substance use disorders (for reviews, see Allan, C. A. (1995). Alcohol problems and anxiety disorders-A critical review. Alcohol & Alcoholism, 30(2)...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2008.03.013

    authors: Robinson J,Sareen J,Cox BJ,Bolton J

    更新日期:2009-01-01 00:00:00

  • Reassurance seeking in the anxiety disorders and OCD: Construct validation, clinical correlates and CBT treatment response.

    abstract:BACKGROUND:Reassurance seeking has been hypothesized to be a key factor in the maintenance of anxiety and obsessive-compulsive disorders according to contemporary cognitive-behavioural therapy (CBT) approaches. The present study sought to examine the structure, clinical correlates, and malleability of reassurance seeki...

    journal_title:Journal of anxiety disorders

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.janxdis.2019.102109

    authors: Rector NA,Katz DE,Quilty LC,Laposa JM,Collimore K,Kay T

    更新日期:2019-10-01 00:00:00

  • Structured and free-recall measures of worry themes: effect of order of presentation on worry report.

    abstract::Structured instruments (SI) or free-recall instruments (FRI) can be used to examine worry themes. In the case where both types are use jointly, order of presentation may influence number and content of free-recall worries. Half of a large undergraduate sample (N = 609) received the SI before the FRI and the other half...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/s0887-6185(00)00032-3

    authors: Laberge M,Fournier S,Freeston MH,Ladouceur R,Provencher MD

    更新日期:2000-07-01 00:00:00

  • Neck-focused panic attacks among Cambodian refugees; a logistic and linear regression analysis.

    abstract::Consecutive Cambodian refugees attending a psychiatric clinic were assessed for the presence and severity of current--i.e., at least one episode in the last month--neck-focused panic. Among the whole sample (N=130), in a logistic regression analysis, the Anxiety Sensitivity Index (ASI; odds ratio=3.70) and the Clinici...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2005.02.001

    authors: Hinton DE,Chhean D,Pich V,Um K,Fama JM,Pollack MH

    更新日期:2006-01-01 00:00:00

  • Ethnoracial differences in anxiety sensitivity: examining the validity of competing anxiety sensitivity index subscales.

    abstract::Despite the increasing number of Americans who are considered to be a part of an ethnoracial minority group, there have been few investigations of the cross-cultural validity of measures of psychopathology. The limited existing literature suggests potential differences between African American (AA) and European Americ...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2012.02.004

    authors: Hunter LR,Keough ME,Timpano KR,Schmidt NB

    更新日期:2012-05-01 00:00:00

  • Cultural factors in social anxiety: a comparison of social phobia symptoms and Taijin kyofusho.

    abstract::The present study examined two forms of culturally-defined social anxiety: social anxiety or phobia, as defined by DSM-IV; (i.e., a concern of public scrutiny or embarrassment) and Taijin Kyofusho (TKS), a Japanese form of social anxiety centered around concern for offending others with inappropriate behavior or offen...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/s0887-6185(97)00004-2

    authors: Kleinknecht RA,Dinnel DL,Kleinknecht EE,Hiruma N,Harada N

    更新日期:1997-03-01 00:00:00

  • An integrated approach to panic prevention targeting the empirically supported risk factors of smoking and anxiety sensitivity: theoretical basis and evidence from a pilot project evaluating feasibility and short-term efficacy.

    abstract::Consistent with a risk reduction model of targeted prevention, the present investigation piloted and empirically evaluated the feasibility and short-term efficacy of a first-generation panic prevention program that targeted two malleable risk factors for panic development-anxiety sensitivity and daily cigarette smokin...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.janxdis.2008.01.005

    authors: Feldner MT,Zvolensky MJ,Babson K,Leen-Feldner EW,Schmidt NB

    更新日期:2008-10-01 00:00:00

  • The Specificity of Inhibitory Control Deficits in Post-Traumatic Stress Disorder: A Dissociation Between the Speed and Reliability of Stopping.

    abstract::Inhibitory control over thoughts, emotions, and actions is challenging for people with Post-Traumatic Stress Disorder (PTSD). Whether specific aspects of inhibitory control are differentially affected in PTSD remains an open question. Here we examined performance on two popular response inhibition tasks in 28 combat V...

    journal_title:Journal of anxiety disorders

    pub_type: 杂志文章

    doi:10.1016/j.janxdis.2020.102278

    authors: Swick D,Ashley V

    更新日期:2020-10-01 00:00:00