Neonatal seizure detection using multichannel display of envelope trend.

abstract：:We determined the incidence of seizures due to acute CNS insults for residents of Rochester, Minnesota, U.S.A., from 1935 through 1984. The age-adjusted incidence rates for 1955-1984, the period of most complete case ascertainment, was 39.0/100,000 person-years (United States 1970 population as standard). The age-adju...

journal_title：Epilepsia

authors： Annegers JF,Hauser WA,Lee JR,Rocca WA

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:The posterior cingulate cortex (PCC)/precuneus is a key hub of the default mode network, whose function is known to be altered in epilepsy. Glutamate and γ-aminobutyric acid (GABA) are the main excitatory and inhibitory neurotransmitters in the central nervous system, respectively. Glutathione (GSH) is the mo...

journal_title：Epilepsia

authors： Gonen OM,Moffat BA,Desmond PM,Lui E,Kwan P,O'Brien TJ

更新日期：2020-12-01 00:00:00

abstract：:Each antiepileptic drug has a characteristic pharmacokinetic profile, and the unique properties of each must be considered when selecting the optimal agent for a particular patient. Detailed pharmacologic data are obtained during the preapproval evaluation of a drug, particularly in early phase studies in healthy volu...

journal_title：Epilepsia

authors： Faught E

更新日期：2001-01-01 00:00:00

abstract：:We examined postoperative changes in the memory function of 68 people with unilateral hippocampal sclerosis (HS) who underwent epilepsy surgery and had no previous clinical memory impairments. One in four with right HS (RHS) and one in five with left HS (LHS) in our sample of 323 people with unilateral HS performed wi...

journal_title：Epilepsia

authors： Baxendale S,Thompson PJ,Sander JW

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:Children with epilepsy have high rates of behavior problems. The purpose was to describe prospectively the association of seizures and behavior problems in children with new-onset seizures. METHODS:Subjects were 224 children with new-onset seizures (aged 4-14 years) and 159 siblings (4-18 years). Caregiver's r...

journal_title：Epilepsia

authors： Austin JK,Dunn DW,Caffrey HM,Perkins SM,Harezlak J,Rose DF

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and tolerability of antiepileptic drugs (AEDs) in elderly individuals with epilepsy. METHODS:We searched four electronic databases as well as bibliographies and conference abstracts. Published and unpublished, randomized, or quasirandomized trials reporting the use of AEDs in people ...

journal_title：Epilepsia

authors： Lezaic N,Gore G,Josephson CB,Wiebe S,Jetté N,Keezer MR

更新日期：2019-07-01 00:00:00

abstract：:[3H]Nimodipine and high-affinity [125I]omega-conotoxin GVIA (CgTX) binding were investigated in membranes from rat cerebral cortex, cerebellum, and hippocampus after electrically and chemically induced seizures. Animals were decapitated 30 min after a single electroconvulsive shock (ECS) or lidocaine-induced seizure a...

journal_title：Epilepsia

authors： Gleiter CH,Cain CJ,Weiss SR,Post RM,Marangos PJ

更新日期：1989-07-01 00:00:00

abstract：:The relationship between diurnal fluctuations in free (unbound) and total plasma carbamazepine levels and the appearance of intermittent side effects was investigated in nine epileptic patients receiving chronic therapy with carbamazepine, alone or in combination with phenobarbital. On a three-times-daily or four-time...

journal_title：Epilepsia

authors： Riva R,Albani F,Ambrosetto G,Contin M,Cortelli P,Perucca E,Baruzzi A

更新日期：1984-08-01 00:00:00

abstract：PURPOSE:To study the neurophysiologic characteristics of epileptic myoclonus in patients with Lennox-Gastaut syndrome (LGS) and myoclonic astatic epilepsy (MAE). METHODS:Three patients with symptomatic LGS (mean age, 15 years +/- 4) and three with cryptogenic MAE (mean age, 9 years +/- 3) were studied. Temporal relati...

journal_title：Epilepsia

authors： Bonanni P,Parmeggiani L,Guerrini R

更新日期：2002-06-01 00:00:00

abstract：PURPOSE:The Atkins diet may induce ketosis as does the ketogenic diet, without restrictions on calories, fluids, protein, or need for an inpatient fast and admission. Our objective was to evaluate the efficacy and tolerability of a modified Atkins diet for intractable childhood epilepsy. METHODS:Twenty children were t...

journal_title：Epilepsia

authors： Kossoff EH,McGrogan JR,Bluml RM,Pillas DJ,Rubenstein JE,Vining EP

更新日期：2006-02-01 00:00:00

abstract：:The Washington Psychosocial Seizure Inventory (WPSI) was used to evaluate the relative extent of psychosocial problems in 379 adults with epilepsy, having differing levels of intelligence and neuropsychological impairment. In general, there were more psychosocial problems when abilities were decreased. Two new scales ...

journal_title：Epilepsia

authors： Dodrill CB

更新日期：1983-02-01 00:00:00

abstract：PURPOSE:To develop an epilepsy-specific comorbidity risk adjustment index for mortality outcomes research. METHODS:Data were extracted from five linked administrative databases in Calgary, Canada from April 1, 1996 to March 31, 2004. Epilepsy patients were defined using a validated ICD-9-CM- and ICD-10-CA-based case d...

journal_title：Epilepsia

authors： St Germaine-Smith C,Liu M,Quan H,Wiebe S,Jette N

更新日期：2011-12-01 00:00:00

abstract：:We report identical twins with supernumerary ring chromosome 19 mosaicism, who had severe refractory epilepsy at an early age. The epilepsy was dominated largely by severe life-threatening tonic seizures. Both twins died, likely as a consequence of their severe epilepsy. They displayed no dysmorphic features. Eight ca...

journal_title：Epilepsia

authors： Shahwan A,Green AJ,Carey A,Stallings RL,O'Flaherty OC,King MD

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:New continuous infusion antiepileptic drugs (cIV-AEDs) offer alternatives to pentobarbital for the treatment of refractory status epilepticus (RSE). However, no prospective randomized studies have evaluated the treatment of RSE. This systematic review compares the efficacy of midazolam (MDL), propofol (PRO),...

journal_title：Epilepsia

authors： Claassen J,Hirsch LJ,Emerson RG,Mayer SA

更新日期：2002-02-01 00:00:00

abstract：PURPOSE:Brivaracetam (BRV) is a new anticonvulsant under development. Although BRV is an analog of levetiracetam (LEV), in addition to being an SV2A ligand, it also inhibits sodium channels in a voltage-dependent manner. The cognitive effects of BRV are uncertain. METHODS:A randomized, double-blind, placebo-controlled...

journal_title：Epilepsia

authors： Meador KJ,Gevins A,Leese PT,Otoul C,Loring DW

更新日期：2011-02-01 00:00:00

abstract：:We conducted a retrospective longitudinal self-controlled study of 124 adult patients treated with resective surgery for medically uncontrolled partial epilepsy from 1949 to 1988. Approximately 65% of the patients experienced > 95% reduction in seizure frequency, and 75% had worthwhile improvement of at least 75% seiz...

journal_title：Epilepsia

authors： Guldvog B,Løyning Y,Hauglie-Hanssen E,Flood S,Bjørnaes H

更新日期：1994-05-01 00:00:00

abstract：:Study of patients with temporal lobe epilepsy and generalized epilepsy revealed no overall seizure type differences, nor overall age-at-onset effects, on MMPI measures of psychopathology. However, statistically significant interactions between seizure type and age at onset were obtained on several MMPI measures, and s...

journal_title：Epilepsia

authors： Hermann BP,Schwartz MS,Karnes WE,Vahdat P

更新日期：1980-02-01 00:00:00

abstract：PURPOSE:Previous studies have shown that the immunosuppressant cyclosporin A (CsA), a specific blocker of the mitochondrial permeability transition (MPT) pore, can dramatically ameliorate the selective neuronal necrosis resulting from ischemia-reperfusion, traumatic brain injury, and N-methyl-d-aspartate (NMDA)-evoked ...

journal_title：Epilepsia

authors： Santos JB,Schauwecker PE

更新日期：2003-08-01 00:00:00

abstract：:Cognitive impairment is the most common comorbidity in children with epilepsy, but its pathophysiology and predisposing conditions remain unknown. Clinical epilepsy characteristics are not conclusive in determining cognitive outcome. Because many children with epilepsy do not have macrostructural magnetic resonance im...

journal_title：Epilepsia

authors： Braakman HM,van der Kruijs SJ,Vaessen MJ,Jansen JF,Debeij-van Hall MH,Vles JS,Aldenkamp AP,Backes WH,Hofman PA

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:The use of primary health care personnel to identify cases of epilepsy and initiate simple treatment protocols has been advocated as a solution to the numeric inadequacy and uneven distribution of medical manpower available for the management of epilepsy in developing countries. This study sought to evaluate th...

journal_title：Epilepsia

authors： Adamolekun B,Mielke JK,Ball DE

更新日期：1999-04-01 00:00:00

abstract：PURPOSE:To determine the lateralizing value of the clinical manifestations of seizures in patients with temporal lobe epilepsy (TLE), we made a retrospective videotape analysis of complex partial seizures (CPS) in 55 patients who underwent temporal lobectomy and were seizure-free postoperatively for >2 years. METHODS:...

journal_title：Epilepsia

authors： Marks WJ Jr,Laxer KD

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:This study evaluated topiramate (TPM) antagonism of glutamate receptors activated by kainate. METHODS:The ability of TPM (3-30 microM) to attenuate kainate (300 microM)-activated cobalt (Co2+) flux through nonselective cation channels permeable to Co2+, Mn2+, and Ca2+ into cultured cerebellar granule neurons [...

journal_title：Epilepsia

authors： Skradski S,White HS

更新日期：2000-01-01 00:00:00

abstract：:Treatment with sodium valproate (VPA) in association with phenobarbital (PB) is accompanied by a greater systemic hyperammonemia than treatment by VPA alone. The anatomical origins of this difference were studied by injecting a dose of 1,500 mg VPA i.v. into six unmedicated patients and six epileptics chronically trea...

journal_title：Epilepsia

authors： Warter JM,Marescaux C,Brandt C,Rumbach L,Micheletti G,Chabrier G,Imler M,Kurtz D

更新日期：1983-10-01 00:00:00

abstract：PURPOSE:Synaptic vesicle protein 2A (SV2A), the binding site for the antiepileptic drug (AED) levetiracetam, has been shown to be involved in the control of neuronal excitability. The aim of the study was to define the expression and cell-specific distribution of SV2A in developmental focal lesions associated with medi...

journal_title：Epilepsia

authors： Toering ST,Boer K,de Groot M,Troost D,Heimans JJ,Spliet WG,van Rijen PC,Jansen FE,Gorter JA,Reijneveld JC,Aronica E

更新日期：2009-06-01 00:00:00

abstract：:Amygdala kindling, the progressive development of seizures following repeated electrical stimulation, has been used as a model of epileptogenesis, neural memory, and the development of behavioral alterations. In an attempt to interfere with the kindling process, electroconvulsive seizures (ECS) were administered 6 h p...

journal_title：Epilepsia

authors： Post RM,Putnam F,Contel NR,Goldman B

更新日期：1984-04-01 00:00:00

abstract：OBJECTIVE:To investigate the characteristics of motor manifestation during convulsive epileptic and psychogenic nonepileptic seizures (PNES), captured using a wrist-worn accelerometer (ACM) device. The main goal was to find quantitative ACM features that can differentiate between convulsive epileptic and convulsive PNE...

journal_title：Epilepsia

authors： Kusmakar S,Karmakar C,Yan B,Muthuganapathy R,Kwan P,O'Brien TJ,Palaniswami MS

更新日期：2019-01-01 00:00:00

abstract：:With microwave diathermy, febrile seizures were produced in epileptic chicks aged 2-5 days. Drugs that enhance GABAergic activity (i.e., GABA, muscimol, and progabide), as well as valproic acid and gamma-hydroxybutyric acid, produced dose-dependent increases in latency to onset of seizures. ...

journal_title：Epilepsia

authors： Pedder SC,Wilcox R,Tuchek J,Johnson DD,Crawford RD

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVE:To compare surgical outcome in mesial temporal lobe epilepsy (MTLE) patients with unilateral hippocampal sclerosis (MTLE-HS) who had or did not have preoperative video-electroencephalographic monitoring (VEEG). METHODS:A prospective study was undertaken with 166 consecutive pharmacoresistant unilateral MTLE-...

journal_title：Epilepsia

authors： Alvim MKM,Morita ME,Yasuda CL,Damasceno BP,Lopes TM,Coan AC,Ghizoni E,Tedeschi H,Cendes F

更新日期：2018-02-01 00:00:00

abstract：:The effects of phenytoin (PHT) on the spontaneous activity of cerebellar Purkinje cells and the drug serum levels have been examined following both intravenous and intraperitoneal administration in rats. Purkinje cell activity was assessed by on-line computer analysis of interspike interval distributions. PHT levels w...

journal_title：Epilepsia

authors： Latham A,Paul DH

更新日期：1980-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to characterize the incidence and etiology of temporal lobe epilepsy (TLE) in a community-based cohort of children with new-onset disease. METHODS:A community-based cohort of 30 children with TLE was studied. The patients had new-onset disease before age 14 years between 1995 and 1999...

journal_title：Epilepsia

authors： Sztriha L,Gururaj AK,Bener A,Nork M

更新日期：2002-01-01 00:00:00