The lack of endothelization after drug-eluting stent implantation as a cause of fatal late stent thrombosis.

abstract：:One of the major mechanisms of action of chemo-radiation is to induce cellular senescence, which exerts crucial roles in age-related pathology. The concept of senescence is evolved, and the novel understanding of senescence-associated reprogramming/stemness has emerged. This new concept emphasizes senescence as not on...

journal_title：Journal of thrombosis and thrombolysis

authors： Dominic A,Hamilton D,Abe JI

更新日期：2020-10-20 00:00:00

abstract：:The use of magnesium therapy for acute myocardial infarction remains controversial despite recent clinical trials such as ISIS-4. Magnesium has numerous beneficial effects in the setting of myocardial infarction, including inhibitory effects on platelet aggregation. Clinical trials of magnesium therapy for myocardial ...

journal_title：Journal of thrombosis and thrombolysis

authors： Rabbani LE

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Sulfonylurea compounds may impair ischemic preconditioning and endogenous fibrinolysis. Increased mortality has been reported in diabetics receiving these drugs prior to admission for acute myocardial infarction when treated by direct angioplasty. Although thrombolytics are currently employed far more freque...

journal_title：Journal of thrombosis and thrombolysis

authors： Halkin A,Roth A,Jonas M,Behar S

更新日期：2001-10-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common arrhythmia in adults and contributes directly to adverse clinical events, ranging from ischemic stroke to heart failure and cardiovascular death. Because the incidence of AF and its attendant complications increase with age, there is a strong and growing need to develop safe...

journal_title：Journal of thrombosis and thrombolysis

authors： Bernacki GM,Becker RC

更新日期：2013-11-01 00:00:00

abstract：:On stimulation of platelets with agonists, for example, thrombin, a rapid rise in intracellular pH is observed. This alkalinization is mediated by an increase in transport activity of the Na(+)/H(+) exchanger isoform NHE1. In addition to this Na(+)/H(+) exchange mechanism, platelets express bicarbonate/chloride exchan...

journal_title：Journal of thrombosis and thrombolysis

authors： Rosskopf D

更新日期：1999-07-01 00:00:00

abstract：:Drug-eluting stents (DES) reduce the incidence of in-stent restenosis (ISR) after primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI). Whether the use of biomarkers might be of utility to identify patients who remain at risk for DES ISR after primary PCI has never been exami...

journal_title：Journal of thrombosis and thrombolysis

authors： Claessen BE,Stone GW,Mehran R,Witzenbichler B,Brodie BR,Wöhrle J,Witkowski A,Guagliumi G,Zmudka K,Henriques JP,Tijssen JG,Sanidas EA,Chantziara V,Hakim D,Leon S,Xu K,Dangas GD

更新日期：2012-08-01 00:00:00

abstract：:Anti-platelet agents or anticoagulants are administered for patients with multiple myeloma (MM) receiving immunomodulatory drugs (IMiDs) to prevent thrombotic events (TEs). However, there is a discrepancy between current guidelines and clinical practice in thromboprophylaxis and the varied incidence of TEs depending o...

journal_title：Journal of thrombosis and thrombolysis

authors： Takaishi K,Tsukamoto S,Ohwada C,Takeuchi M,Kawasaki Y,Nagai Y,Mishina T,Yamazaki M,Isshiki Y,Kayamori K,Kimura K,Hino Y,Oshima-Hasegawa N,Mitsukawa S,Takeda Y,Mimura N,Iseki T,Nakaseko C,Sakaida E

更新日期：2019-07-01 00:00:00

abstract：:Amlodipine, commonly used for relief of ischemic symptoms in coronary artery disease (CAD), may affect clopidogrel-induced antiplatelet effects. It remains unknown if ranolazine, an antianginal drug that constitutes a pharmacologic alternative to calcium channel blockade, interferes with clopidogrel-induced antiplatel...

journal_title：Journal of thrombosis and thrombolysis

authors： Pelliccia F,Greco C,Gaudio C,Rosano G,Vitale C,Marazzi G,Rollini F,Angiolillo DJ

更新日期：2015-10-01 00:00:00

abstract：:Data regarding possible mechanisms of aspirin (ASA) resistance in patients with recurrent myocardial infarction (MI) or vascular ischemia are limited. Five major possible mechanisms of ASA resistance are documented in the primary literature and are discussed in this paper. These mechanisms include: (1) inadequate bloc...

journal_title：Journal of thrombosis and thrombolysis

authors： Cambria-Kiely JA,Gandhi PJ

更新日期：2002-02-01 00:00:00

abstract：AIMS:Cancer patients have an increased risk for thromboembolism (TE). Factor V 1691 G-A(Leiden) (FVL) and prothrombin (PT) G20210A mutation are common inherited risk factor for TE. The aim of the study is to evaluate the prevalence of FVL and PT G20210A polymorphism in cancer patients with and without TE as compared to...

journal_title：Journal of thrombosis and thrombolysis

authors： Eroglu A,Ulu A,Cam R,Kurtman C,Akar N

更新日期：2007-02-01 00:00:00

abstract：:The following manuscript presents two cases of ischemic stroke secondary to traumatic internal carotid artery thrombosis with concomitant middle cerebral artery thrombosis occurring very rarely in the medico-legal practice. Penetrating neck trauma due to an occupational accident and multiple head and neck trauma secon...

journal_title：Journal of thrombosis and thrombolysis

authors： Karnecki K,Jankowski Z,Kaliszan M

更新日期：2014-10-01 00:00:00

abstract：:Intracerebral hemorrhage (ICH) can be a devastating complication of coronavirus disease (COVID-19). We aimed to assess risk factors associated with ICH in this population. We performed a retrospective cohort study of adult patients admitted to NYU Langone Health system between March 1 and April 27 2020 with a positive...

journal_title：Journal of thrombosis and thrombolysis

authors： Melmed KR,Cao M,Dogra S,Zhang R,Yaghi S,Lewis A,Jain R,Bilaloglu S,Chen J,Czeisler BM,Raz E,Lord A,Berger JS,Frontera JA

更新日期：2020-09-24 00:00:00

abstract：BACKGROUND:There are several new strategies proposed to improve the outcome of patients with ST-elevation myocardial infarction (STEMI). One approach is the resurgent use of facilitated percutaneous coronary interventions (PCI). Until recently, deciding whether immediate PCI after combined treatment (facilitated PCI) i...

journal_title：Journal of thrombosis and thrombolysis

authors： Di Pasquale P,Cannizzaro S,Parrinello G,Giambanco F,Vitale G,Fasullo S,Scalzo S,Ganci F,La Manna N,Sarullo F,La Rocca G,Paterna S

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To report our experience with use of thrombolysis with streptokinase during cardiopulmonary resuscitation of patients with cardiac arrest due to myocardial infarction. DESIGN:A case series. METHODS:Thrombolytic therapy (streptokinase) was administered during cardiopulmonary resuscitation of 4 patients with ...

journal_title：Journal of thrombosis and thrombolysis

authors： Aliyev F,Habeb M,Babalik E,Karadag B

更新日期：2005-12-01 00:00:00

abstract：:The REG2 Anticoagulation System consists of pegnivacogin, a subcutaneously administered aptamer factor IXa inhibitor, and its intravenous active control agent, anivamersen. Its effect on thrombin generation is unknown. A prospectively designed thrombin generation study was conducted within the phase 1 ascending dose s...

journal_title：Journal of thrombosis and thrombolysis

authors： Vavalle JP,Rusconi CP,Zelenkofske S,Wargin WA,Ortel TL,Alexander JH,Povsic TJ,Becker RC

更新日期：2014-10-01 00:00:00

abstract：:Venous thromboembolism (VTE) is an important cause of morbidity and mortality in Western countries. The incidence rate of VTE is estimated at 1-2 cases per 1000 annually. This study was a population-based cohort study of previously treatment naïve patients with a first occurrence of venous thromboembolism (VTE), using...

journal_title：Journal of thrombosis and thrombolysis

authors： Wändell P,Forslund T,Danin Mankowitz H,Ugarph-Morawski A,Eliasson S,Braunschwieg F,Holmström M

更新日期：2019-11-01 00:00:00

abstract：UNLABELLED:Compression therapy is still not widely used for patients with deep vein thrombosis (DVT). This report provides information on Italian doctors' use of elastic stockings (ES) after acute DVT and identifies some predictors of prescription. MATERIAL AND METHODS:The MASTER multicenter registry collected informa...

journal_title：Journal of thrombosis and thrombolysis

authors： Arpaia G,Carpenedo M,Pistelli R,Mastrogiacomo O,Cimminiello C,Agnelli G

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:Recent data suggest substantial variations in the treatment of acute myocardial infarction based on age, race, gender and socioeconomic status. We evaluated the use of primary angioplasty (PA) in acute myocardial infarction (AMI) in elderly and minority patients treated at an urban, teaching hospital. SUBJECTS...

journal_title：Journal of thrombosis and thrombolysis

authors： Regueiro CR,Gill N,Hart A,Crawshaw L,Hentosz T,Shannon RP

更新日期：2003-04-01 00:00:00

abstract：:Gastrointestinal bleeding is the most common bleeding complication during anticoagulant therapy. A reliable bleeding risk score can help the clinician assess risk of bleeding in individual patients and select the anticoagulant regimen. This study retrospectively analyzed the data of patients with atrial fibrillation w...

journal_title：Journal of thrombosis and thrombolysis

authors： Lv MN,Zheng XC,Zhang HQ,Xu FD,Wu TT,Chen WJ,Xia XT,Fu JL,Jiang SJ,Zhang JH

更新日期：2021-01-01 00:00:00

abstract：:Background: There is compelling evidence that coronary atherosclerosis represents a chronic active process characterized by inflammation, impaired fibrinolysis, intermittent plaque rupture, and luminal thrombosis. Identifying readily measurable plasma markers of procoagulant activity may have an important role in both...

journal_title：Journal of thrombosis and thrombolysis

authors： Rho R,Tracy RP,Bovill EG,Ball SP,Becker RC

更新日期：1995-01-01 00:00:00

abstract：:To investigate the relationship between circulating microRNA 223 (miR-223) levels and clopidogrel responsiveness in patients with coronary heart disease. A total of 62 consecutive patients with troponin-negative non-ST elevation acute coronary syndrome (NSTE-ACS) scheduled for elective percutaneous coronary interventi...

journal_title：Journal of thrombosis and thrombolysis

authors： Zhang YY,Zhou X,Ji WJ,Shi R,Lu RY,Li JL,Yang GH,Luo T,Zhang JQ,Zhao JH,Jiang TM,Li YM

更新日期：2014-07-01 00:00:00

abstract：:Unfractionated heparin (UFH) plasma protein binding and elimination might be impaired in patients with chronic kidney disease (CKD-defined as creatinine clearance <60 ml/min). It is currently unknown at which UFH bolus dose persistent prolongation of activated partial thromboplastin time (aPTT) occurs in ST-segment el...

journal_title：Journal of thrombosis and thrombolysis

authors： Kikkert WJ,van Brussel PM,Damman P,Claessen BE,van Straalen JP,Vis MM,Baan J Jr,Koch KT,Peters RJ,de Winter RJ,Piek JJ,Tijssen JG,Henriques JP

更新日期：2016-04-01 00:00:00

abstract：:The current, global situation regarding the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic and its potentially devastating clinical manifestations, i.e. coronavirus disease 2019 (COVID-19), took the world by storm, as millions of people have been infected worldwide and more than 1,600,000 patien...

journal_title：Journal of thrombosis and thrombolysis

authors： Moschonas IC,Tselepis AD

更新日期：2021-01-15 00:00:00

abstract：:Medicinal plants have been used for treatment of human ailments since ancient times. Objective of this study is to document the effect of herbal drugs on anticoagulant therapy. The material for this review was taken mostly from PubMed and the Cochrane database of systematic reviews. Some other relevant references were...

journal_title：Journal of thrombosis and thrombolysis

authors： Akram M,Rashid A

更新日期：2017-10-01 00:00:00

abstract：:Continuous flow left ventricular assist devices (CF-LVAD) require therapeutic anticoagulation which is often interrupted for procedures or bleeding. Prior to the availability of four factor prothrombin complex concentrate (4F-PCC) in the United States, warfarin was held and its effects reversed by vitamin K or fresh f...

journal_title：Journal of thrombosis and thrombolysis

authors： Rimsans J,Levesque A,Lyons E,Sylvester K,Givertz MM,Mehra MR,Stewart GC,Connors JM

更新日期：2018-08-01 00:00:00

abstract：:It has been reported that platelet expression and plasma levels of soluble P-selectin are increased in patients with unstable coronary artery syndromes. However, the origin of soluble P-selectin remains unknown. We sought to determine whether platelet expression of P-selectin correlates with plasma levels in the popul...

journal_title：Journal of thrombosis and thrombolysis

authors： Gurbel PA,Kereiakes DJ,Serebruany VL

更新日期：2000-08-01 00:00:00

abstract：:Oxidative stress-induced platelet apoptosis is one among the many causes for the development and progression of many disorders like cardiovascular diseases, arthritis, Alzheimer's disease and many chronic inflammatory responses. Many studies have demonstrated the less optimal effect of N-acetyl cysteine (NAC) in oxida...

journal_title：Journal of thrombosis and thrombolysis

authors： Paul M,Thushara RM,Jagadish S,Zakai UI,West R,Kemparaju K,Girish KS

更新日期：2017-02-01 00:00:00

abstract：:The goal of platelet function testing in the catheterization laboratory is to provide information about the platelet contributions to the risk of thrombotic or hemorrhagic events and optimization of anti-platelet therapy for percutaneous interventions. We present several illustrative cases in which platelet monitoring...

journal_title：Journal of thrombosis and thrombolysis

authors： Mukherjee D,Chew DP,Robbins M,Yadav JS,Raymond RE,Moliterno DJ

更新日期：2001-04-01 00:00:00

abstract：:Heparin induced thrombocytopenia (HIT) is a life and limb-threatening complication of heparin exposure. The misdiagnosis of this disease can have major consequences on the patients. The objective of this study was to evaluate a diagnostic strategy that combines the 4Ts score with the result of HemosIL® AcuStar HIT-IgG...

journal_title：Journal of thrombosis and thrombolysis

authors： Marashi-Sabouni Z,Vayne C,Ibrahim-Kosta M,Guidon C,Loundou A,Guery EA,Morange PE,Camoin-Jau L

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Venous thromboembolism (VTE) is a significant cause of mortality and morbidity in medical patients. Although thromboprophylaxis with enoxaparin reduces the risk of VTE in these patients, the optimal duration of therapy is not currently known. The EXCLAIM (EXtended CLinical prophylaxis in Acutely Ill Medical ...

journal_title：Journal of thrombosis and thrombolysis

authors： Hull RD,Schellong SM,Tapson VF,Monreal M,Samama MM,Turpie AG,Wildgoose P,Yusen RD

更新日期：2006-08-01 00:00:00