Prevalence of Factor V 1691 G-A (Leiden) and prothrombin G20210A polymorphisms and the risk of venous thrombosis among cancer patients.

abstract：PURPOSE:Recent data suggest substantial variations in the treatment of acute myocardial infarction based on age, race, gender and socioeconomic status. We evaluated the use of primary angioplasty (PA) in acute myocardial infarction (AMI) in elderly and minority patients treated at an urban, teaching hospital. SUBJECTS...

journal_title：Journal of thrombosis and thrombolysis

authors： Regueiro CR,Gill N,Hart A,Crawshaw L,Hentosz T,Shannon RP

更新日期：2003-04-01 00:00:00

abstract：:A significant proportion of the outcomes reported in trials assessing venous thromboembolism (VTE) prophylaxis in medical patients are related to asymptomatic events found on routine imaging studies. The implications of these events are controversial. Moreover, such trials did not always reflect the patient mix in tod...

journal_title：Journal of thrombosis and thrombolysis

authors： Vardi M,Steinberg M,Haran M,Cohen S

更新日期：2012-07-01 00:00:00

abstract：:Cirrhosis is a consequence of prolonged liver injury and is characterised by extensive tissue fibrosis: the deposition of collagen-rich extracellular matrix. The haemostatic balance is disordered in cirrhosis and coagulation activation appears to promote fibrosis. In spite of recent studies demonstrating a role for an...

journal_title：Journal of thrombosis and thrombolysis

authors： Egan K,Dillon A,Dunne E,Kevane B,Galvin Z,Maguire P,Kenny D,Stewart S,Ainle FN

更新日期：2017-01-01 00:00:00

abstract：:Aortic stenosis (AS) accounts for the majority of valvular abnormalities requiring surgical intervention. Platelet dysfunction has been demonstrated among patients with severe aortic stenosis which may predispose patients to bleeding or ischemic events. Surgical aortic valve replacement (AVR) is the standard therapy f...

journal_title：Journal of thrombosis and thrombolysis

authors： Lynch DR Jr,Dantzler D,Robbins M,Zhao D

更新日期：2013-05-01 00:00:00

abstract：:Background: Renal vein thrombosis (RVT) complicating the nephrotic syndrome is associated with a poor prognosis. Methods/Results: RVT was diagnosed in 12 of 60 patients with a diagnosis of nephrotic syndrome suggested by computed tomography (CT) and subsequently confirmed by selective renal angiography. Fifty patients...

journal_title：Journal of thrombosis and thrombolysis

authors： Wu ZL,Zhou KR,Liao Lt

更新日期：1996-01-01 00:00:00

abstract：:Pump thrombosis remains a serious complication of implantable ventricular assist device therapy and is associated with increased risk of morbidity and mortality. Optimal management strategies remain controversial and are guided largely by limited literature and expert opinion. Medical management of pump thrombosis, in...

journal_title：Journal of thrombosis and thrombolysis

authors： Weeks P,Sieg A,Rajapreyar I,Nathan S,Jumean M,Patel M,Radovancevic R,Kar B,Gregoric I

更新日期：2018-11-01 00:00:00

abstract：:The home prothrombin time/international normalized ratio (PT/INR) self-management could be convenient for patients, enhancing treatment compliance and improving the quality of the oral anticoagulation. However, patient self-management (PSM) of oral anticoagulation may not be feasible for up to half of the patients due...

journal_title：Journal of thrombosis and thrombolysis

authors： da Silva Saraiva S,Orsi FA,Santos MP,Machado T,Montalvão S,Costa-Lima C,de Paula EV,Colella MP,Annichino-Bizzacchi J

更新日期：2016-07-01 00:00:00

abstract：:Right ventricular (RV) enlargement, determined via the ratio of the right to left ventricular diameters (RV/LV) by CT imaging is used to classify the severity of acute pulmonary embolism (PE) and impacts treatment decisions. The RV/LV ratio may be an unreliable marker of RV dysfunction, due in part to the complex RV g...

journal_title：Journal of thrombosis and thrombolysis

authors： Marginean A,Putnam A,Hirai T,Serritella A,Besser SA,Lee M,Friant J,Blair J,Shah A,Nathan S,Chung J,Paul J

更新日期：2020-07-01 00:00:00

abstract：:Stroke and venous thromboembolism (VTE) are serious and preventable thrombotic events in patients with atrial fibrillation (AF) and who undergo surgery or hospitalization, respectively. Nevertheless, thromboprophylaxis remains greatly underused. The National Quality Forum, the Agency for Healthcare Research and Qualit...

journal_title：Journal of thrombosis and thrombolysis

authors： Eymin G,Jaffer AK

更新日期：2014-01-01 00:00:00

abstract：:Argatroban is a parenteral direct thrombin inhibitor labeled for anticoagulation in patients with confirmed or suspected heparin-induced thrombocytopenia in the United States. Currently there are no studies evaluating bleeding risk factors in Intensive Care Unit patients.To determine bleeding risk factors associated w...

journal_title：Journal of thrombosis and thrombolysis

authors： Doepker B,Mount KL,Ryder LJ,Gerlach AT,Murphy CV,Philips GS

更新日期：2012-11-01 00:00:00

abstract：:To investigate the prevalence of permanent atrial fibrillation (AF), its clinical associated conditions and treatment status in the elderly population in rural Greece. 720 people (46.1% males) older than 65 years (mean age: 72.5 +/- 5.7 years) living in four villages in rural Greece were screened with an electrocardio...

journal_title：Journal of thrombosis and thrombolysis

authors： Ninios I,Bogossian H,Zarse M,Lazaridou F,Dimitriadis K,Ninios V,Lemke B,Louridas G

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:To describe and compare warfarin therapy use and outcomes between warfarin-receiving patients in hospice or palliative care (HPC) and not in HPC. METHODS:This retrospective, matched analysis examined warfarin-receiving patients who did (study cohort) and did not receive (control cohort) HPC services between 20...

journal_title：Journal of thrombosis and thrombolysis

authors： Hill RR,Martinez KD,Delate T,Witt DM

更新日期：2009-04-01 00:00:00

abstract：:We describe the results of a novel complete care package using point-of-care INR testing and computerized decision support for the management of oral anticoagulation by nurse-led primary care clinics in the United Kingdom. We found such therapy to be as safe and effective as traditional hospital-based care for oral an...

journal_title：Journal of thrombosis and thrombolysis

authors： Fitzmaurice DA

更新日期：2006-02-01 00:00:00

abstract：:Thromboembolic events are frequent and serious complications of acute lymphoblastic leukaemia treatment. The importance of chemotherapy in the pathogenesis of this increased risk is enhanced by the fact that thrombosis rarely occurs at diagnosis. Our study aims at investigating the effect of chemotherapy on pro-coagul...

journal_title：Journal of thrombosis and thrombolysis

authors： Pluchart C,Poitevin G,Colinart-Thomas M,Guimard G,Audonnet S,Terryn C,Nguyen P

更新日期：2019-08-01 00:00:00

abstract：:Coronary artery fistulae (CAF) are rare congenital or acquired in which a connection forms between one of the coronary arteries and a heart chamber or with other vessels. This paper describes three cases of CAF along with their initial presentation, imaging findings and management. The first case is a rare form of CAF...

journal_title：Journal of thrombosis and thrombolysis

authors： Ali M,Kassem KM,Osei K,Effat M

更新日期：2019-08-01 00:00:00

abstract：:Poloxamer 188 is a surfactant with hemorheological, antithrombotic, and neutrophil-inhibitory properties. This agent has been demonstrated to reduce infarct size and to improve left ventricular function in animal models of myocardial infarction and reperfusion, and recently in a randomized trial of patients receiving ...

journal_title：Journal of thrombosis and thrombolysis

authors： Kelly RF,Hursey TL,Patel RB,Parrillo JE,Schaer GL

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Impairment of coronary microvascular perfusion is common among patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). Cardiovascular magnetic resonance imaging (CMR) can identify microvascular obstruction (MO) following reperfusion of S...

journal_title：Journal of thrombosis and thrombolysis

authors： Appelbaum E,Kirtane AJ,Clark A,Pride YB,Gelfand EV,Harrigan CJ,Kissinger KV,Manning WJ,Gibson CM

更新日期：2009-02-01 00:00:00

abstract：:On stimulation of platelets with agonists, for example, thrombin, a rapid rise in intracellular pH is observed. This alkalinization is mediated by an increase in transport activity of the Na(+)/H(+) exchanger isoform NHE1. In addition to this Na(+)/H(+) exchange mechanism, platelets express bicarbonate/chloride exchan...

journal_title：Journal of thrombosis and thrombolysis

authors： Rosskopf D

更新日期：1999-07-01 00:00:00

abstract：:Anticoagulation is often used in superior vena cava syndrome (SVCS) associated with cancer (i.e malignant SVCS), even without thrombosis, but its effect on outcomes has not been reported. We aimed to determine factors and outcomes associated with thrombosis and anticoagulation in malignant SVCS. Patients with malignan...

journal_title：Journal of thrombosis and thrombolysis

authors： Ratzon R,Tamir S,Friehmann T,Livneh N,Dudnik E,Rozental A,Hamburger-Avnery O,Pereg D,Derazne E,Brenner B,Raanani P,Ten Cate H,Spectre G,Leader A

更新日期：2019-01-01 00:00:00

abstract：:Apixaban is effective and safe for preventing stroke, and its usage has increased exponentially in recent years. However, data concerning the therapeutic range of apixaban is limited. This study determined the trough and peak levels of apixaban-specific anti-factor Xa activity (AFXaA) in acute ischemic stroke patients...

journal_title：Journal of thrombosis and thrombolysis

authors： Shin H,Cho MC,Kim RB,Kim CH,Choi NC,Kim SK,Koh EH

更新日期：2018-02-01 00:00:00

abstract：:Data on LA/LAA thrombus resolution after rivaroxaban treatment has not been established. The aim of the present study was to compare the efficacy and safety on the resolution of LA/LAA thrombus between rivaroxaban and warfarin in nonvalvular atrial fibrillation (AF) patients. 80 AF patients with LA/LAA thrombus betwee...

journal_title：Journal of thrombosis and thrombolysis

authors： Ke HH,He Y,Lv XW,Zhang EH,Wei Z,Li JY

更新日期：2019-08-01 00:00:00

abstract：:Argatroban, a hepatically metabolized direct thrombin inhibitor, is approved for anticoagulation in patients with or at risk of heparin-induced thrombocytopenia (HIT) undergoing percutaneous coronary intervention (PCI). We investigated the effect of renal function on argatroban therapy during PCI. From previous argatr...

journal_title：Journal of thrombosis and thrombolysis

authors： Hursting MJ,Jang IK

更新日期：2010-01-01 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a life-threatening thrombotic microangiopathy caused by severely reduced activity of the von-Willebrand factor-cleaving protease ADAMTS13, mainly caused by anti-ADAMTS-13 antibodies. Although several test systems for ADAMTS13 measurement exist, long turn-around times hamper...

journal_title：Journal of thrombosis and thrombolysis

authors： Stratmann J,Ward JN,Miesbach W

更新日期：2020-10-01 00:00:00

abstract：:Prasugrel has been shown to be superior to clopidogrel in the setting of ACS patients undergoing coronary angioplasty. However, few data have been reported so far on those patients who switch from clopidogrel to prasugrel after coronary angioplasty. Aim of the current study was to evaluate the safety of prasugrel load...

journal_title：Journal of thrombosis and thrombolysis

authors： De Luca G,Verdoia M,Schaffer A,Suryapranata H,Parodi G,Antoniucci D,Marino P

更新日期：2014-10-01 00:00:00

abstract：:Point-of-care whole blood coagulation tests are critical in the management of patients who undergo percutaneous coronary intervention. The Hemochron and HemoTec devices have been traditionally used to measure the activated clotting time (ACT) in the cardiac catheterization laboratory. The heparin management test (HMT)...

journal_title：Journal of thrombosis and thrombolysis

authors： Tsimikas S,Beyer R,Hassankhani A

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Oxidative stress play an important role triggering platelet/endothelial activation. AGI-1067 is a novel, phenolic antioxidant, and vascular protectant which dose-dependently inhibits PEA biomarkers in vitro. Whether treatment with AGI-1067 alters platelets in vivo is not known. We serially assessed release o...

journal_title：Journal of thrombosis and thrombolysis

authors： Serebruany V,Malinin A,Qiu FH,Xu XC,Kunsch C,Scott R,ALPS Study Group.

更新日期：2009-05-01 00:00:00

abstract：:The risk benefit decision in providing anticoagulation for patients with brain metastases is amongst the most difficult decisions faced by clinicians. The purpose of our study was to evaluate both the risk of intracerebral hemorrhage (ICH) associated with anticoagulation therapy and the effect of anticoagulation on su...

journal_title：Journal of thrombosis and thrombolysis

authors： Hunter BD,Minichiello T,Bent S

更新日期：2017-10-01 00:00:00

abstract：:We report a case of infective endocarditis (IE) involving the posterior mitral leaflet (PML) with calcific embolization in a patient with hypertrophic obstructive cardiomyopathy (HOCM). Amongst HOCM patients with IE, the anterior mitral leaflet and basal septal myocardium are almost always involved due to the endocard...

journal_title：Journal of thrombosis and thrombolysis

authors： Lather N,Niziolek K,Toth P,Harris DM

更新日期：2015-02-01 00:00:00

abstract：:The impact of platelet parameters on the cardiovascular risk is still debated. Gender differences in platelet volume indexes and turnover have been previously reported, potentially conditioning their role in the development of coronary artery disease (CAD). However, few studies have addressed, so far, the impact of ge...

journal_title：Journal of thrombosis and thrombolysis

authors： Negro F,Verdoia M,Tonon F,Nardin M,Kedhi E,De Luca G,Novara Atherosclerosis Study Group (NAS).

更新日期：2020-05-01 00:00:00

abstract：:One of the major mechanisms of action of chemo-radiation is to induce cellular senescence, which exerts crucial roles in age-related pathology. The concept of senescence is evolved, and the novel understanding of senescence-associated reprogramming/stemness has emerged. This new concept emphasizes senescence as not on...

journal_title：Journal of thrombosis and thrombolysis

authors： Dominic A,Hamilton D,Abe JI

更新日期：2020-10-20 00:00:00