Efficacy and safety of rivaroxaban on the resolution of left atrial/left atrial appendage thrombus in nonvalvular atrial fibrillation patients.

abstract：:Pump thrombosis remains a serious complication of implantable ventricular assist device therapy and is associated with increased risk of morbidity and mortality. Optimal management strategies remain controversial and are guided largely by limited literature and expert opinion. Medical management of pump thrombosis, in...

journal_title：Journal of thrombosis and thrombolysis

authors： Weeks P,Sieg A,Rajapreyar I,Nathan S,Jumean M,Patel M,Radovancevic R,Kar B,Gregoric I

更新日期：2018-11-01 00:00:00

abstract：:Drug-eluting stents (DES) reduce the incidence of in-stent restenosis (ISR) after primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI). Whether the use of biomarkers might be of utility to identify patients who remain at risk for DES ISR after primary PCI has never been exami...

journal_title：Journal of thrombosis and thrombolysis

authors： Claessen BE,Stone GW,Mehran R,Witzenbichler B,Brodie BR,Wöhrle J,Witkowski A,Guagliumi G,Zmudka K,Henriques JP,Tijssen JG,Sanidas EA,Chantziara V,Hakim D,Leon S,Xu K,Dangas GD

更新日期：2012-08-01 00:00:00

abstract：:Increased level of soluble cell adhesion molecules may be a marker for atherosclerosis and/or reflect complication of the atherosclerotic plaque. To test whether expression of cell adhesion molecules is more pronounced in unstable versus stable coronary plaques, we measured the serum level of soluble E-selectin (sE-se...

journal_title：Journal of thrombosis and thrombolysis

authors： Galvani M,Ferrini D,Ottani F,Nanni C,Ramberti A,Amboni P,Iamele L,Vernocchi A,Nicolini FA

更新日期：2000-01-01 00:00:00

abstract：:In this feasibility study, a novel catheter prototype for laser thrombolysis under the guidance of optical coherence tomography (OCT) was designed and evaluated in a preclinical model. Human arteries and veins were integrated into a physiological flow model and occluded with thrombi made from the Chandler Loop. There ...

journal_title：Journal of thrombosis and thrombolysis

authors： Berndt R,Rusch R,Hummitzsch L,Lutz M,Heß K,Huenges K,Panholzer B,Otte C,Haneya A,Lutter G,Schlaefer A,Cremer J,Groß J

更新日期：2017-04-01 00:00:00

abstract：:The objective was to compare the pharmacodynamic (PD) and pharmacokinetic (PK) effects of ticagrelor with clopidogrel among subjects of Hispanic ethnicity, as the PD and PK effects of antiplatelet agents among Hispanics are not specifically known. This was a randomised, open-label, crossover PD/PK study of 40 Hispanic...

journal_title：Journal of thrombosis and thrombolysis

authors： Price MJ,Clavijo L,Angiolillo DJ,Carlson G,Caplan R,Teng R,Maya J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:We studied whether 2 MHz transcranial color-coded duplex ultrasound (TCCD), combined with a second generation ECA, accelerate IV rtPA-thrombolysis in the acute phase of MCA stroke more than TCCD monitoring alone. METHODS:Non-randomized acute MCA stroke patients undergoing IV rtPA-thrombolysis and 2 MHZ-TCCD...

journal_title：Journal of thrombosis and thrombolysis

authors： Perren F,Loulidi J,Poglia D,Landis T,Sztajzel R

更新日期：2008-04-01 00:00:00

abstract：:Intravenous (IV) thrombolysis is the treatment in ischemic stroke, but only the minority of patients receive this medication. The primary objective of this study was to explore the reasons associated with the decision not to offer IV thrombolysis to stroke patients admitted to the Stroke Unit (SU). We conducted a retr...

journal_title：Journal of thrombosis and thrombolysis

authors： Cappellari M,Bosco M,Forlivesi S,Tomelleri G,Micheletti N,Carletti M,Bovi P

更新日期：2016-11-01 00:00:00

abstract：:Infarct artery stenting with adjunctive abciximab therapy is widely used treatment for patients with acute myocardial infarction (AMI). However, bleeding complications have been associated with a worse clinical outcome. Randomized trials in elective patients have shown that postprocedural protamine administration is s...

journal_title：Journal of thrombosis and thrombolysis

authors： Parodi G,De Luca G,Moschi G,Bellandi B,Valenti R,Migliorini A,Carrabba N,Antoniucci D

更新日期：2010-11-01 00:00:00

abstract：:Patients with Coronavirus-associated disease-2019 (COVID-19) display alterations of the hemostatic system and the presence of a prothrombotic status frequently leading to vascular complications. However, the impact of COVID-19 on platelet activity, aggregation and agglutination still needs to be clarified. We measured...

journal_title：Journal of thrombosis and thrombolysis

authors： Ruberto F,Chistolini A,Curreli M,Frati G,Marullo AGM,Biondi-Zoccai G,Mancone M,Sciarretta S,Miraldi F,Alessandri F,Ceccarelli G,Barone F,Santoro C,Alvaro D,Pugliese F,Pulcinelli FM,Policlinico Umberto I COVID-19 Group.

更新日期：2021-01-02 00:00:00

abstract：:C-reactive protein (CRP) is an independent predictor of risk in ACS patients, and it has been previously shown that percutaneous coronary intervention (PCI) is associated with an early rise in CRP. To assess the long-term relationship between PCI and CRP, we compared CRP levels at baseline, 30 days, 4 months and 24 mo...

journal_title：Journal of thrombosis and thrombolysis

authors： Ray KK,Nazer B,Cairns R,Michael Gibson C,Cannon CP

更新日期：2010-07-01 00:00:00

abstract：:The US Surgical Care Improvement Project (SCIP) has approved two performance measures to improve venous thromboembolism (VTE) prevention. SCIP-VTE-2 measures the proportion of surgery patients who received appropriate VTE prophylaxis within 24 h prior to surgery to 24 h after surgery. This study assesses the current r...

journal_title：Journal of thrombosis and thrombolysis

authors： Deitelzweig SB,Lin J,Hussein M,Battleman D

更新日期：2010-07-01 00:00:00

abstract：:Amlodipine, commonly used for relief of ischemic symptoms in coronary artery disease (CAD), may affect clopidogrel-induced antiplatelet effects. It remains unknown if ranolazine, an antianginal drug that constitutes a pharmacologic alternative to calcium channel blockade, interferes with clopidogrel-induced antiplatel...

journal_title：Journal of thrombosis and thrombolysis

authors： Pelliccia F,Greco C,Gaudio C,Rosano G,Vitale C,Marazzi G,Rollini F,Angiolillo DJ

更新日期：2015-10-01 00:00:00

abstract：:Data comparing the patient characteristics, management and outcomes for dabigatran versus warfarin major bleeding in the practice setting are limited. We performed a retrospective single health system study of atrial fibrillation patients with dabigatran or warfarin major bleeding from October 2010 through September 2...

journal_title：Journal of thrombosis and thrombolysis

authors： Smythe MA,Forman MJ,Bertran EA,Hoffman JL,Priziola JL,Koerber JM

更新日期：2015-10-01 00:00:00

abstract：:The home prothrombin time/international normalized ratio (PT/INR) self-management could be convenient for patients, enhancing treatment compliance and improving the quality of the oral anticoagulation. However, patient self-management (PSM) of oral anticoagulation may not be feasible for up to half of the patients due...

journal_title：Journal of thrombosis and thrombolysis

authors： da Silva Saraiva S,Orsi FA,Santos MP,Machado T,Montalvão S,Costa-Lima C,de Paula EV,Colella MP,Annichino-Bizzacchi J

更新日期：2016-07-01 00:00:00

abstract：:In a previous study, we observed that one injection of 500 microg of DNA for the plasmid encoding for vascular endothelial growth factor (ph VEGF(165)) into one site in a rat myocardial infarction model resulted in neovascularization confined to angiomatous structures that did not contribute to regional myocardial blo...

journal_title：Journal of thrombosis and thrombolysis

authors： Kloner RA,Dow J,Chung G,Kedes LH

更新日期：2000-12-01 00:00:00

abstract：:Anticoagulation treatment is effective in preventing both death and recurrence in patients with venous thromboembolism (VTE), but at the same time confers a substantial risk of bleeding complications. The aim of this study was to examine the rate of and predictors for bleeding complications in VTE patients on warfarin...

journal_title：Journal of thrombosis and thrombolysis

authors： Sandén P,Renlund H,Svensson PJ,Själander A

更新日期：2016-02-01 00:00:00

abstract：:Among atrial fibrillation (AF) patients undergoing percutaneous coronary intervention (PCI), rivaroxaban with background antiplatelet therapy significantly reduced the first occurrence of bleeding compared to triple therapy with warfarin. This study hypothesized that total bleeding events, including those beyond the f...

journal_title：Journal of thrombosis and thrombolysis

authors： Chi G,Yee MK,Kalayci A,Kerneis M,AlKhalfan F,Mehran R,Bode C,Halperin JL,Verheugt FWA,Wildgoose P,van Eickels M,Lip GYH,Cohen M,Peterson ED,Fox KAA,Gibson CM

更新日期：2018-10-01 00:00:00

abstract：:Coagulation dysfunction and inflammatory status were compared between diabetic and non-diabetic COVID-19 patients. The standardized mean difference (SMD) and its 95% confidence interval (CI) was computed for the difference of inflammatory and hypercoagulability markers. The levels of serum ferritin (standardized mean ...

journal_title：Journal of thrombosis and thrombolysis

authors： Varikasuvu SR,Varshney S,Dutt N

更新日期：2020-09-05 00:00:00

abstract：:We assessed the effect of the intercellular mediator of inflammation, platelet activating factor (PAF), on platelet function. The interaction between PAF and the platelet agonists ADP, thrombin and convulxin was analyzed in vitro in whole blood with the use of flow cytometry and was further characterized with the use ...

journal_title：Journal of thrombosis and thrombolysis

authors： Keating FK,Schneider DJ

更新日期：2009-07-01 00:00:00

abstract：:It has been reported that platelet expression and plasma levels of soluble P-selectin are increased in patients with unstable coronary artery syndromes. However, the origin of soluble P-selectin remains unknown. We sought to determine whether platelet expression of P-selectin correlates with plasma levels in the popul...

journal_title：Journal of thrombosis and thrombolysis

authors： Gurbel PA,Kereiakes DJ,Serebruany VL

更新日期：2000-08-01 00:00:00

abstract：:The following manuscript presents two cases of ischemic stroke secondary to traumatic internal carotid artery thrombosis with concomitant middle cerebral artery thrombosis occurring very rarely in the medico-legal practice. Penetrating neck trauma due to an occupational accident and multiple head and neck trauma secon...

journal_title：Journal of thrombosis and thrombolysis

authors： Karnecki K,Jankowski Z,Kaliszan M

更新日期：2014-10-01 00:00:00

abstract：:Based on their mode of action, it is reasonable to expect that the combination therapy of aspirin and a vitamin K antagonist (VKA) may be more beneficial in preventing (athero) thrombotic complications in high-risk patients for cardiovascular events. However, there is no consensus about additional aspirin use in the m...

journal_title：Journal of thrombosis and thrombolysis

authors： Loualidi A,Bredie SH,Janssen MC

更新日期：2009-05-01 00:00:00

abstract：:Pulmonary embolism (PE) is a leading cause of cardiovascular mortality. We intended to evaluate the awareness and management status of PE among Chinese physicians and provide the basis for establishing Chinese clinical guidelines on PE. We designed a nationwide survey to collect data on physicians' awareness of diagno...

journal_title：Journal of thrombosis and thrombolysis

authors： Zhang M,Zhang YX,Zhang Z,Wang J,Shao X,Xie WM,Wan J,Zhai ZG,Wang C

更新日期：2019-04-01 00:00:00

abstract：:We describe the results of a novel complete care package using point-of-care INR testing and computerized decision support for the management of oral anticoagulation by nurse-led primary care clinics in the United Kingdom. We found such therapy to be as safe and effective as traditional hospital-based care for oral an...

journal_title：Journal of thrombosis and thrombolysis

authors： Fitzmaurice DA

更新日期：2006-02-01 00:00:00

abstract：:To identify the pathogenesis of a Chinese woman diagnosed with dysfibrinogenemia. A patient from Nanjing presented with a low plasma concentration of fibrinogen and a normal level of antigen of fibrinogen. This abnormality was also detected in her son. To detect whether the genetic mutation was responsible for the dys...

journal_title：Journal of thrombosis and thrombolysis

authors： Zhou N,Xu P,Zhou M,Xu Y,Li P,Chen B,Ouyang J,Zhou R

更新日期：2017-07-01 00:00:00

abstract：:Anti-platelet agents or anticoagulants are administered for patients with multiple myeloma (MM) receiving immunomodulatory drugs (IMiDs) to prevent thrombotic events (TEs). However, there is a discrepancy between current guidelines and clinical practice in thromboprophylaxis and the varied incidence of TEs depending o...

journal_title：Journal of thrombosis and thrombolysis

authors： Takaishi K,Tsukamoto S,Ohwada C,Takeuchi M,Kawasaki Y,Nagai Y,Mishina T,Yamazaki M,Isshiki Y,Kayamori K,Kimura K,Hino Y,Oshima-Hasegawa N,Mitsukawa S,Takeda Y,Mimura N,Iseki T,Nakaseko C,Sakaida E

更新日期：2019-07-01 00:00:00

abstract：:In patients with active cancer and acute venous thromboembolism (VTE), the low-molecular-weight-heparin (LMWH) dalteparin is more effective than vitamin K antagonist (VKA) in reducing the risk of recurrent venous thromboembolism (rVTE) without increasing the risk of bleeding. However, the relative benefit of LMWH vers...

journal_title：Journal of thrombosis and thrombolysis

authors： Woodruff S,Lee AYY,Carrier M,Feugère G,Abreu P,Heissler J

更新日期：2019-05-01 00:00:00

abstract：:The adverse impact of the development of cardiogenic shock in the setting of acute myocardial infarction was first described by Killip and Kimball in 1967. While the in-hospital mortality rate in patients with myocardial infarction and no evidence of heart failure was only 6%, the mortality rate in those patients who ...

journal_title：Journal of thrombosis and thrombolysis

authors： Levine GN,Hochman JS

更新日期：1995-01-01 00:00:00

abstract：:The predictive value of and the influencing factors associated with early neurological improvement (ENI) among patients with acute basilar artery occlusion (BAO) have not been well studied. The present study aimed to evaluate whether ENI predicted a better functional outcome and to identify the influencing factors of ...

journal_title：Journal of thrombosis and thrombolysis

authors： Sun X,Zhang H,Tong X,Gao F,Deng Y,Ma G,Ma N,Mo D,Song L,Liu L,Huo X,Miao Z

更新日期：2021-01-01 00:00:00

abstract：:In experimentally induced myocardial ischemia, mild hypothermia (33-35 degrees C) has a robust cardioprotective effect. Tissue plasminogen activator (t-PA) is a profibrinolytic enzyme that is released from the vascular endothelial cells in response to ischemia and other injurious stimuli. t-PA has also been found to h...

journal_title：Journal of thrombosis and thrombolysis

authors： van der Pals J,Götberg M,Olivecrona GK,Brogren H,Jern S,Erlinge D

更新日期：2010-04-01 00:00:00