Anti-coagulant activity of plants: mini review.

abstract：:The risk benefit decision in providing anticoagulation for patients with brain metastases is amongst the most difficult decisions faced by clinicians. The purpose of our study was to evaluate both the risk of intracerebral hemorrhage (ICH) associated with anticoagulation therapy and the effect of anticoagulation on su...

journal_title：Journal of thrombosis and thrombolysis

authors： Hunter BD,Minichiello T,Bent S

更新日期：2017-10-01 00:00:00

abstract：:Data on LA/LAA thrombus resolution after rivaroxaban treatment has not been established. The aim of the present study was to compare the efficacy and safety on the resolution of LA/LAA thrombus between rivaroxaban and warfarin in nonvalvular atrial fibrillation (AF) patients. 80 AF patients with LA/LAA thrombus betwee...

journal_title：Journal of thrombosis and thrombolysis

authors： Ke HH,He Y,Lv XW,Zhang EH,Wei Z,Li JY

更新日期：2019-08-01 00:00:00

abstract：:Subtilisin QK, a new fibrinolytic enzyme, could cleave directly cross-linked fibrin in vitro. To verify the thrombolytic function of Subtilisin QK in vivo, the thrombolytic effect of purified Subtilisin QK on tail-thrombus of mouse was investigated. After injected with carrageenan, the tail-thrombus of Subtilisin QK t...

journal_title：Journal of thrombosis and thrombolysis

authors： Yan F,Yan J,Sun W,Yao L,Wang J,Qi Y,Xu H

更新日期：2009-11-01 00:00:00

abstract：:Patients with inflammatory bowel disease (IBD) have a 1.5-3.5-fold higher risk of thromboembolism when compared to the non-IBD population and the risk is much more prominent at the time of a flare. Arterial thromboembolism (ischemic stroke, focal white matter ischemia, cardiac ischemia, peripheral vascular disease and...

journal_title：Journal of thrombosis and thrombolysis

authors： Kohoutova D,Moravkova P,Kruzliak P,Bures J

更新日期：2015-05-01 00:00:00

abstract：:Inherited afibrinogenemia and hypofibrinogenemia are rare bleeding disorders characterized by markedly reduced levels of fibrinogen in blood. Thrombotic complications in these disorders have been rarely described. We performed a multicenter retrospective study and reviewed the occurrence of thrombotic complications am...

journal_title：Journal of thrombosis and thrombolysis

authors： Rottenstreich A,Lask A,Schliamser L,Zivelin A,Seligsohn U,Kalish Y

更新日期：2016-08-01 00:00:00

abstract：:Recurrent stroke is common immediately following a transient ischemic attack (TIA) or ischemic stroke. Dual antiplatelet therapy (DAPT) with clopidogrel and aspirin may provide greater protection against subsequent stroke than monotherapy. Electronic databases were searched for randomized clinical trials (RCTs) compar...

journal_title：Journal of thrombosis and thrombolysis

authors： Kheiri B,Osman M,Abdalla A,Haykal T,Swaid B,Ahmed S,Chahine A,Hassan M,Bachuwa G,Al Qasmi M,Bhatt DL

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:Recent data suggest substantial variations in the treatment of acute myocardial infarction based on age, race, gender and socioeconomic status. We evaluated the use of primary angioplasty (PA) in acute myocardial infarction (AMI) in elderly and minority patients treated at an urban, teaching hospital. SUBJECTS...

journal_title：Journal of thrombosis and thrombolysis

authors： Regueiro CR,Gill N,Hart A,Crawshaw L,Hentosz T,Shannon RP

更新日期：2003-04-01 00:00:00

abstract：:Schistosomes are parasitic platyhelminths that currently infect over 200 million people and cause the chronic debilitating disease schistosomiasis. While these large intravascular parasites can disturb blood flow, surprisingly they do not appear to provoke thrombus formation around them in vivo. In order to determine ...

journal_title：Journal of thrombosis and thrombolysis

authors： Da'dara AA,de Laforcade AM,Skelly PJ

更新日期：2016-05-01 00:00:00

abstract：:Fondaparinux (FPX), a selective inhibitor of factor Xa, is widely used for the prophylaxis of venous thromboembolism (VTE) after total joint arthroplasty. However, the association between plasma FPX concentration and adverse events and the occurrence of VTE has not been clarified thus far. We aimed to prospectively ev...

journal_title：Journal of thrombosis and thrombolysis

authors： Yukizawa Y,Inaba Y,Watanabe S,Yajima S,Kobayashi N,Ishida T,Iwamoto N,Hyonmin C,Nakamura M,Saito T

更新日期：2012-11-01 00:00:00

abstract：:In experimentally induced myocardial ischemia, mild hypothermia (33-35 degrees C) has a robust cardioprotective effect. Tissue plasminogen activator (t-PA) is a profibrinolytic enzyme that is released from the vascular endothelial cells in response to ischemia and other injurious stimuli. t-PA has also been found to h...

journal_title：Journal of thrombosis and thrombolysis

authors： van der Pals J,Götberg M,Olivecrona GK,Brogren H,Jern S,Erlinge D

更新日期：2010-04-01 00:00:00

abstract：UNLABELLED:Platelet P-selectin and activated glycoprotein IIb-IIIa (GPIIb-IIIa) are markers of platelet activation and mediates platelet aggregation. Prasugrel (Pras) 5 mg may be used in very elderly (VE) acute coronary syndrome (ACS) patients undergoing PCI, but its effect on platelet P-selectin and activated GPIIb-II...

journal_title：Journal of thrombosis and thrombolysis

authors： Wagner H,Lood C,Borna C,Gidlöf O,Truedsson L,Brown P,Zhou C,Winters K,Jakubowski JA,Erlinge D

更新日期：2016-10-01 00:00:00

abstract：:Since the reports by Weismann and Tobin in 1958 and Roberts et al. in 1964 called attention to paradoxical thrombosis in patients treated with heparin, the thrombotic aspect of the heparin-induced thrombocytopenia syndrome (HIT) has been emphasized. Yet to this day, the mechanism of thrombosis associated with HIT (HIT...

journal_title：Journal of thrombosis and thrombolysis

authors： Walenga JM,Jeske WP,Messmore HL

更新日期：2000-11-01 00:00:00

abstract：:Warfarin is a commonly used medication with a narrow therapeutic index. The initiation of warfarin requires consideration of a variety of factors, which include reviewing the indications and contraindications for this agent, performing a thorough clinical assessment along with a risk-benefit analysis for anticoagulati...

journal_title：Journal of thrombosis and thrombolysis

authors： Erban S

更新日期：1999-04-01 00:00:00

abstract：:Coagulation dysfunction and inflammatory status were compared between diabetic and non-diabetic COVID-19 patients. The standardized mean difference (SMD) and its 95% confidence interval (CI) was computed for the difference of inflammatory and hypercoagulability markers. The levels of serum ferritin (standardized mean ...

journal_title：Journal of thrombosis and thrombolysis

authors： Varikasuvu SR,Varshney S,Dutt N

更新日期：2020-09-05 00:00:00

abstract：:The relationship between vascular-specific epicardial adipose tissue (vEAT) volume and myocardial ischemia measured by fractional flow reserve (FFR) was not well investigated. Patients with typical and atypical chest pain undergoing coronary computed tomographic angiography scan followed by invasive coronary angiograp...

journal_title：Journal of thrombosis and thrombolysis

authors： Shan D,Wang X,Dou G,Zhang W,Jing J,He B,Li Y,Chen Y,Yang J

更新日期：2020-10-17 00:00:00

abstract：BACKGROUND:The available evidence suggests strongly that intravascular thrombosis is mediated predominantly by tissue-factor and its activation of factor X, which in the presence of factor Va, calcium, and phospholipid (prothrombinase complex) effectively converts prothrombin to thrombin. In vitro experiments have show...

journal_title：Journal of thrombosis and thrombolysis

authors： Spencer FA,Ball SP,Zhang Q,Liu L,Benoit S,Becker RC

更新日期：2000-04-01 00:00:00

abstract：INTRODUCTION:While the CURE trial demonstrated the benefits of clopidogrel in acute coronary syndromes, patients receiving glycoprotein IIb/IIIa antagonists were excluded. Given the frequent coadministration of these two medications, we sought to examine their interaction and their combined effect on platelet inhibitio...

journal_title：Journal of thrombosis and thrombolysis

authors： Talreja D,Lubbe D,Orford JL,Lennon R,DiBattiste PM,Berger PB

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Impairment of coronary microvascular perfusion is common among patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). Cardiovascular magnetic resonance imaging (CMR) can identify microvascular obstruction (MO) following reperfusion of S...

journal_title：Journal of thrombosis and thrombolysis

authors： Appelbaum E,Kirtane AJ,Clark A,Pride YB,Gelfand EV,Harrigan CJ,Kissinger KV,Manning WJ,Gibson CM

更新日期：2009-02-01 00:00:00

abstract：:We report a case of infective endocarditis (IE) involving the posterior mitral leaflet (PML) with calcific embolization in a patient with hypertrophic obstructive cardiomyopathy (HOCM). Amongst HOCM patients with IE, the anterior mitral leaflet and basal septal myocardium are almost always involved due to the endocard...

journal_title：Journal of thrombosis and thrombolysis

authors： Lather N,Niziolek K,Toth P,Harris DM

更新日期：2015-02-01 00:00:00

abstract：:The following manuscript presents two cases of ischemic stroke secondary to traumatic internal carotid artery thrombosis with concomitant middle cerebral artery thrombosis occurring very rarely in the medico-legal practice. Penetrating neck trauma due to an occupational accident and multiple head and neck trauma secon...

journal_title：Journal of thrombosis and thrombolysis

authors： Karnecki K,Jankowski Z,Kaliszan M

更新日期：2014-10-01 00:00:00

abstract：:Venous thromboembolism (VTE) is a common complication of hematologic malignancies. Prolonged periods of thrombocytopenia are experienced universally by patients undergoing treatment for these diseases, yet data to guide management of anticoagulation in this setting are lacking. To obtain data on the management and out...

journal_title：Journal of thrombosis and thrombolysis

authors： Samuelson Bannow BT,Walter RB,Gernsheimer TB,Garcia DA

更新日期：2017-11-01 00:00:00

abstract：:Amniotic fluid embolism (AFE) is a catastrophic condition in the peripartum period and still remains as a leading cause of maternal death. Although over 80% of cases of AFE cases are accompanied by coagulopathy, the pathology of disseminated intravascular coagulation is not well understood not only because of its rari...

journal_title：Journal of thrombosis and thrombolysis

authors： Fudaba M,Tachibana D,Misugi T,Nakano A,Koyama M

更新日期：2020-07-29 00:00:00

abstract：:Sickle cell disease (SCD) is characterised by abnormal coagulopathy and angiogenesis although their relationships in two common genotypes, homozygous (HbSS) SCD and sickle-haemoglobin C disease (HbSC), are unexplored. We measured markers of platelet activation (soluble P-selectin [sP-selectin]), fibrinolysis (D-dimer)...

journal_title：Journal of thrombosis and thrombolysis

authors： Blann AD,Mohan JS,Bareford D,Lip GY

更新日期：2008-04-01 00:00:00

abstract：:Little is known about the impact of thrombolytic agents on in-hospital outcomes in the Middle East. The objective of this study was to evaluate the impact of thrombolytic agents on in-hospital outcomes in ST-segment elevation myocardial infarction (STEMI) patients in six Middle Eastern countries. Gulf Registry of Acut...

journal_title：Journal of thrombosis and thrombolysis

authors： Al-Zakwani I,Ali A,Zubaid M,Panduranga P,Sulaiman K,Abusham A,Almahmeed W,Al-Motarreb A,Al Suwaidi J,Amin H

更新日期：2012-04-01 00:00:00

abstract：:Thrombosis resolution is an important component of treatment for deep vein thrombosis (DVT) and multiple anticoagulants are now available. It is unknown whether rivaroxaban contributes to a higher degree of thrombus resolution compared to conventional anticoagulation with warfarin. Our objective was to compare thrombu...

journal_title：Journal of thrombosis and thrombolysis

authors： Houghton DE,Lekah A,Macedo TA,Hodge D,Saadiq RA,Little Y,Casanegra AI,McBane RD,Wysokinski WE

更新日期：2020-02-01 00:00:00

abstract：:Several autopsy studies showed microthrombi in pulmonary circulation of severe COVID-19 patients. The major limitation of these investigations is that the autopsy provided static information. Some of these alterations could be secondary to the disseminated intravascular coagulation (DIC) observed as the final standard...

journal_title：Journal of thrombosis and thrombolysis

authors： do Espírito Santo DA,Lemos ACB,Miranda CH

更新日期：2020-11-01 00:00:00

abstract：:Many hospitals have implemented warfarin dosing nomograms to improve patient safety. To our knowledge, no study has assessed the impact inpatient warfarin initiation has in both medical and surgical patients, on safety outcomes post discharge. To evaluate the impact of a suggested institutional nomogram for the initia...

journal_title：Journal of thrombosis and thrombolysis

authors： Chamoun N,Macías CG,Donovan JL,Klugman R,Gore J,Salameh P,Tran MT

更新日期：2017-05-01 00:00:00

abstract：:While antithrombotic therapy of acute myocardial infarction is clearly beneficial, substantial controversy exists regarding the optimal regimen. In particular, while aspirin alone has proven highly effective in reducing rates of reinfarction, stroke, and death following acute coronary occlusion, heparin has not clearl...

journal_title：Journal of thrombosis and thrombolysis

authors： Ridker PM,O'Donnell CJ,Hennekens CH

更新日期：1995-01-01 00:00:00

abstract：:Acutely ill medical patients are at significant risk of venous thromboembolism (VTE). Thromboprophylaxis can substantially reduce the incidence of VTE, but to be optimally effective must consist of the correct choice of agent, at an appropriate dose, and for sufficient duration. Increasing evidence suggests that VTE r...

journal_title：Journal of thrombosis and thrombolysis

authors： Stark JE,Smith WJ

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:We studied whether 2 MHz transcranial color-coded duplex ultrasound (TCCD), combined with a second generation ECA, accelerate IV rtPA-thrombolysis in the acute phase of MCA stroke more than TCCD monitoring alone. METHODS:Non-randomized acute MCA stroke patients undergoing IV rtPA-thrombolysis and 2 MHZ-TCCD...

journal_title：Journal of thrombosis and thrombolysis

authors： Perren F,Loulidi J,Poglia D,Landis T,Sztajzel R

更新日期：2008-04-01 00:00:00