Clinical application of procedural platelet monitoring during percutaneous coronary intervention among patients at increased bleeding risk.

abstract：:The authors present a fatal case of late thrombosis of paclitaxel-eluting stent implanted in the left main stem occurring 6 months after the procedure and 3 weeks after the cessation of clopidogrel. An autopsy has shown the lack of endothelization of deployed stent. ...

journal_title：Journal of thrombosis and thrombolysis

authors： Jakabcin J,Bystron M,Spacek R,Veselka J,Kvasnak M,Kala P,Malý J,Cervinka P

更新日期：2008-10-01 00:00:00

abstract：:The link between myeloma and thrombosis is well established. Monoclonal gammopathy of undetermined significance (MGUS) has also been associated with an increased risk of thrombosis. It was recently demonstrated that patients with myeloma display changes in thromboelastometry that may indicate a prothrombotic state. Th...

journal_title：Journal of thrombosis and thrombolysis

authors： Crowley MP,Quinn S,Coleman E,Eustace JA,Gilligan OM,O'Shea SI

更新日期：2015-02-01 00:00:00

abstract：:Dual antiplatelet therapy with aspirin and clopidogrel are recommended as adjuncts to fibrinolytic-treated patients with ST-elevation myocardial infarction (STEMI). However, the role of switching to ticagrelor within 24 h of fibrinolytics compared with clopidogrel continuation in this setting is uncertain. Hence, we c...

journal_title：Journal of thrombosis and thrombolysis

authors： Kheiri B,Osman M,Abdalla A,Haykal T,Barbarawi M,Zayed Y,Hicks M,Ahmed S,Bachuwa G,Hassan M,Bhatt DL

更新日期：2018-10-01 00:00:00

abstract：:Recent gene knockout studies on mice have shown the role of toll-like receptor 9 (TLR9) in resolution of venous thromboembolism (VTE) through sterile inflammation. However, the role of a putative functional TLR9 polymorphism (rs5743836) in risk assessment of VTE recurrence remains unknown. The aim of our study was to ...

journal_title：Journal of thrombosis and thrombolysis

authors： Ahmad A,Sundquist K,Zöller B,Svensson PJ,Sundquist J,Memon AA

更新日期：2017-07-01 00:00:00

abstract：:Infarct artery stenting with adjunctive abciximab therapy is widely used treatment for patients with acute myocardial infarction (AMI). However, bleeding complications have been associated with a worse clinical outcome. Randomized trials in elective patients have shown that postprocedural protamine administration is s...

journal_title：Journal of thrombosis and thrombolysis

authors： Parodi G,De Luca G,Moschi G,Bellandi B,Valenti R,Migliorini A,Carrabba N,Antoniucci D

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:There are several new strategies proposed to improve the outcome of patients with ST-elevation myocardial infarction (STEMI). One approach is the resurgent use of facilitated percutaneous coronary interventions (PCI). Until recently, deciding whether immediate PCI after combined treatment (facilitated PCI) i...

journal_title：Journal of thrombosis and thrombolysis

authors： Di Pasquale P,Cannizzaro S,Parrinello G,Giambanco F,Vitale G,Fasullo S,Scalzo S,Ganci F,La Manna N,Sarullo F,La Rocca G,Paterna S

更新日期：2006-04-01 00:00:00

abstract：:Erythropoietin (EPO) was hypothesized to mitigate reperfusion injury, in part via mobilization of endothelial progenitor cells (EPCs). The REVEAL trial found no reduction in infarct size with a single dose of EPO (60,000 U) in patients with ST-segment elevation myocardial infarction. In a substudy, we aimed to determi...

journal_title：Journal of thrombosis and thrombolysis

authors： Povsic TJ,Najjar SS,Prather K,Zhou J,Adams SD,Zavodni KL,Kelly F,Melton LG,Hasselblad V,Heitner JF,Raman SV,Barsness GW,Patel MR,Kim RJ,Lakatta EG,Harrington RA,Rao SV

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:We studied whether 2 MHz transcranial color-coded duplex ultrasound (TCCD), combined with a second generation ECA, accelerate IV rtPA-thrombolysis in the acute phase of MCA stroke more than TCCD monitoring alone. METHODS:Non-randomized acute MCA stroke patients undergoing IV rtPA-thrombolysis and 2 MHZ-TCCD...

journal_title：Journal of thrombosis and thrombolysis

authors： Perren F,Loulidi J,Poglia D,Landis T,Sztajzel R

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Sulfonylurea compounds may impair ischemic preconditioning and endogenous fibrinolysis. Increased mortality has been reported in diabetics receiving these drugs prior to admission for acute myocardial infarction when treated by direct angioplasty. Although thrombolytics are currently employed far more freque...

journal_title：Journal of thrombosis and thrombolysis

authors： Halkin A,Roth A,Jonas M,Behar S

更新日期：2001-10-01 00:00:00

abstract：:Prasugrel has been shown to be superior to clopidogrel in the setting of ACS patients undergoing coronary angioplasty. However, few data have been reported so far on those patients who switch from clopidogrel to prasugrel after coronary angioplasty. Aim of the current study was to evaluate the safety of prasugrel load...

journal_title：Journal of thrombosis and thrombolysis

authors： De Luca G,Verdoia M,Schaffer A,Suryapranata H,Parodi G,Antoniucci D,Marino P

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The aspirin induced platelet aggregation has been reported to be mediated through the inhibition of platelet prostaglandin synthesis. This compound has also been recently reported to stimulate nitric oxide synthesis in platelets. Since nitric oxide has been reported to produce fibrinogen/fibrinolytic effect,...

journal_title：Journal of thrombosis and thrombolysis

authors： Karmohapatra SK,Kahn NN,Sinha AK

更新日期：2007-10-01 00:00:00

abstract：:The aim of this study was to evaluate the association of prothrombotic gene polymorphisms [factor V Leiden (FVL) 1691GA, factor VII (FVII) 10976GA, FVII HVR4, platelet membrane glycoproteins GP1BA 1018CT, GP1BA VNTR, integrin ITGB3 1565TC, integrin ITGA2 807CT and methylenetetrahydrofolate reductase (MTHFR) 677C/T], p...

journal_title：Journal of thrombosis and thrombolysis

authors： Dogra RK,Das R,Ahluwalia J,Kumar RM,Talwar KK

更新日期：2012-08-01 00:00:00

abstract：:Half of patients with atrial fibrillation (AF) and elevated stroke risk do not receive anticoagulation (AC). Explanations for undertreatment may relate to provider lack of confidence with or knowledge of the CHA2DS2-VASc stroke calculator, unfamiliarity with direct oral anticoagulants (DOACs), or uncertainty about use...

journal_title：Journal of thrombosis and thrombolysis

authors： Amroze A,Mazor K,Crawford S,O'Day K,McManus DD,Kapoor A

更新日期：2019-11-01 00:00:00

abstract：:Cancer is associated with an increased risk of venous thromboembolism of four to sixfold. Cancer-related interventions such as chemotherapy, hormonal therapy and indwelling central venous catheters also increase the risk of venous thromboembolism. Low molecular weight heparin for at least 3-6 months is the current sta...

journal_title：Journal of thrombosis and thrombolysis

authors： Franco-Moreno A,Cabezón-Gutiérrez L,Palka-Kotlowsa M,Villamayor-Delgado M,García-Navarro M

更新日期：2019-04-01 00:00:00

abstract：:Anticoagulant plasma concentrations and patient characteristics might affect the benefit-risk balance of therapy. The study objective was to assess the impact of model-predicted rivaroxaban exposure and patient characteristics on outcomes in patients receiving rivaroxaban for venous thromboembolism (VTE) prophylaxis (...

journal_title：Journal of thrombosis and thrombolysis

authors： Reinecke I,Solms A,Willmann S,Spiro TE,Peters G,Weitz JI,Mueck W,Garmann D,Schmidt S,Zhang L,Fox KAA,Berkowitz SD

更新日期：2020-07-01 00:00:00

abstract：:The current, global situation regarding the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic and its potentially devastating clinical manifestations, i.e. coronavirus disease 2019 (COVID-19), took the world by storm, as millions of people have been infected worldwide and more than 1,600,000 patien...

journal_title：Journal of thrombosis and thrombolysis

authors： Moschonas IC,Tselepis AD

更新日期：2021-01-15 00:00:00

abstract：:Patients with carotid atherosclerosis, especially the elderly population, take antithrombotic medicine regularly. However, no previous meta-analysis has focused on one of the possible side effects of such drugs, namely intraplaque hemorrhage (IPH). To determine whether antiplatelet drugs or anticoagulants are associat...

journal_title：Journal of thrombosis and thrombolysis

authors： Cao X,Zhang J,Geng D

更新日期：2019-07-01 00:00:00

abstract：:Based on their mode of action, it is reasonable to expect that the combination therapy of aspirin and a vitamin K antagonist (VKA) may be more beneficial in preventing (athero) thrombotic complications in high-risk patients for cardiovascular events. However, there is no consensus about additional aspirin use in the m...

journal_title：Journal of thrombosis and thrombolysis

authors： Loualidi A,Bredie SH,Janssen MC

更新日期：2009-05-01 00:00:00

abstract：:Aspirin (acetylsalicylic acid) is one of the main therapeutics in prevention of thrombo-embolic vascular events. Its efficiency is proved in the prevention of cardiovascular events. However, antiplatelet effect of aspirin is not absolute in all patients and some patients experience thrombo-embolic events despite aspir...

journal_title：Journal of thrombosis and thrombolysis

authors： Pamukcu B

更新日期：2007-06-01 00:00:00

abstract：:The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis. There is ample evidence from both laboratory and clinical studies to suggest that in addition to...

journal_title：Journal of thrombosis and thrombolysis

authors： Gorog DA

更新日期：2018-05-01 00:00:00

abstract：:Infective endocarditis (IE) remains a severe illness with high mortality rate, despite advances in antibiotic therapy and cardiac surgery. If infectious bacteria and platelets are two key players of human IE vegetation developmental process, their interactions and respective roles in fully developed late-stage IE vege...

journal_title：Journal of thrombosis and thrombolysis

authors： Baudoin JP,Camoin-Jau L,Prasanth A,Habib G,Lepidi H,Hannachi N

更新日期：2020-08-04 00:00:00

abstract：:Time to treatment with thrombolytic therapy has been recognized as an important factor in the treatment of patients with acute myocardial infarction: By restoring infarct-related artery patency earlier, clinical outcome is improved. Of the several components of time delay between the onset of pain to opening of the ar...

journal_title：Journal of thrombosis and thrombolysis

authors： Cannon CP

更新日期：1996-01-01 00:00:00

abstract：:We report a case of infective endocarditis (IE) involving the posterior mitral leaflet (PML) with calcific embolization in a patient with hypertrophic obstructive cardiomyopathy (HOCM). Amongst HOCM patients with IE, the anterior mitral leaflet and basal septal myocardium are almost always involved due to the endocard...

journal_title：Journal of thrombosis and thrombolysis

authors： Lather N,Niziolek K,Toth P,Harris DM

更新日期：2015-02-01 00:00:00

abstract：:We hypothesized that women are more prone to develop coronary dissections during PCI due to potential balloon-oversizing or gender specific plaque and vascular characteristics. To date, a gender related difference in edge dissection has not been systematically studied. The Massachusetts General Hospital Optical Cohere...

journal_title：Journal of thrombosis and thrombolysis

authors： Zeglin-Sawczuk M,Jang IK,Kato K,Yonetsu T,Kim S,Choi SY,Kratlian C,Lee H,Dauerman HL

更新日期：2013-11-01 00:00:00

abstract：:Previous studies have reported a circadian variation in the onset of ST-segment elevation myocardial infarction (STEMI). However, underlying mechanisms for the circadian variation have not been fully elucidated. We investigated the relationship between onset of STEMI and the underlying pathology using optical coherenc...

journal_title：Journal of thrombosis and thrombolysis

authors： Araki M,Yonetsu T,Kurihara O,Nakajima A,Lee H,Soeda T,Minami Y,Higuma T,Kimura S,Takano M,Yan BP,Adriaenssens T,Boeder NF,Nef HM,Kim CJ,Crea F,Kakuta T,Jang IK

更新日期：2020-07-10 00:00:00

abstract：:Patients with COVID-19 are known to be at risk of developing both venous, arterial and microvascular thrombosis, due to an excessive immuno-thrombogenic response to the SARS-CoV-2 infection. Overlapping syndromes of COVID-19 associated coagulopathy with consumptive coagulopathy and microangiopathy can be seen in criti...

journal_title：Journal of thrombosis and thrombolysis

authors： Fan BE,Ng J,Chan SSW,Christopher D,Tso ACY,Ling LM,Young BE,Wong LJL,Sum CLL,Tan HT,Ang MK,Lim GH,Ong KH,Kuperan P,Chia YW

更新日期：2020-10-24 00:00:00

abstract：:Edoxaban, alongside other direct oral anticoagulants (DOAC), is increasingly used for prevention of thromboembolism, including stroke. Despite DOAC therapy, however, annual stroke rate in patients with atrial fibrillation remains 1-2%. Rapid exclusion of relevant anticoagulation is necessary to guide thrombolysis or r...

journal_title：Journal of thrombosis and thrombolysis

authors： Härtig F,Birschmann I,Peter A,Hörber S,Ebner M,Sonnleitner M,Spencer C,Bombach P,Stefanou MI,Kuhn J,Mengel A,Ziemann U,Poli S

更新日期：2020-10-01 00:00:00

abstract：:Arterial thrombosis is the leading causes of morbidity and mortality worldwide, whereas venous thrombosis is the most common preventable cause of hospital death. In either case, venous and arterial thrombosis should be considered autonomous entities, with only minor overlaps in terms of risk factors, predisposing cond...

journal_title：Journal of thrombosis and thrombolysis

authors： Lippi G,Favaloro EJ,Franchini M

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:To describe and compare warfarin therapy use and outcomes between warfarin-receiving patients in hospice or palliative care (HPC) and not in HPC. METHODS:This retrospective, matched analysis examined warfarin-receiving patients who did (study cohort) and did not receive (control cohort) HPC services between 20...

journal_title：Journal of thrombosis and thrombolysis

authors： Hill RR,Martinez KD,Delate T,Witt DM

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The endothelial ADP receptor P2Y(1) is responsible for a large part of the reactive hyperemia following cardiac ischemia. Tissue plasminogen activator (t-PA) increases during reactive hyperemia. We postulated that the release of t-PA during reactive hyperemia could be mitigated through blocking the coronary ...

journal_title：Journal of thrombosis and thrombolysis

authors： Olivecrona GK,Götberg M,Harnek J,Jacobson KA,Jern S,Erlinge D

更新日期：2007-10-01 00:00:00