Patterns of oxygenation after thoracotomy.

abstract：:Protein kinase C (PKC) is a key regulatory enzyme that has been implicated as a molecular target for the action of general anaesthetics. We have determined the effects of halothane on the translocation and down-regulation of conventional PKC (cPKC) by analysing the subcellular distribution of PKC activity, [3H]phorbol...

journal_title：British journal of anaesthesia

authors： Hemmings HC Jr,Adamo AI

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Anterograde, but not retrograde, amnesia has been demonstrated following midazolam administration. However, there have been no studies investigating whether or not immediate retrograde amnesia can be produced with midazolam. METHODS:After ethics committee approval and consent, 40 adult patients undergoing s...

journal_title：British journal of anaesthesia

authors： Bulach R,Myles PS,Russnak M

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Infraclavicular axillary vein cannulation is not commonly used for central venous access because identifying the surface landmarks is difficult. Ultrasound guided axillary vein puncture has not been well described. We assessed ultrasound imaging to guide catheterization of the infraclavicular axillary vein. ...

journal_title：British journal of anaesthesia

authors： Sharma A,Bodenham AR,Mallick A

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Plethysmographic variability index (PVI) is an accurate predictor of fluid responsiveness in mechanically ventilated patients. However, the site of measurement of the plethysmographic waveform impacts its morphology and its respiratory variation. The goal of this study was to investigate the ability of PVI t...

journal_title：British journal of anaesthesia

authors： Desgranges FP,Desebbe O,Ghazouani A,Gilbert K,Keller G,Chiari P,Robin J,Bastien O,Lehot JJ,Cannesson M

更新日期：2011-09-01 00:00:00

abstract：:We have studied the relationship between gas exchange and mechanical frequency response during high frequency jet ventilation (HFJV) at 0.5-5.0 Hz in anaesthetized pigs. The mechanical gain curve showed a minimal "anti-resonant" response at 0.8 Hz (f1) and a maximal "resonant" response at 5.0 Hz (f2). This finding may...

journal_title：British journal of anaesthesia

authors： Lin ES,Jones MJ,Mottram SD,Smith BE,Smith G

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:An important cause of coagulopathy in cardiac surgery is impaired thrombin generation. While plasma is often used to correct this element of the coagulopathy, studies in vitro suggest that prothrombin complex concentrates (PCCs) might be more effective. Comparative data, however, are scant. METHODS:We compa...

journal_title：British journal of anaesthesia

authors： Fitzgerald J,Lenihan M,Callum J,McCluskey SA,Srinivas C,van Rensburg A,Karkouti K

更新日期：2018-05-01 00:00:00

abstract：:We have assessed tracheal intubating conditions in 60 ASA I or II patients after induction of anaesthesia with propofol 2.5 mg kg-1 and alfentanil 10 or 20 micrograms kg-1 with or without i.v. lignocaine 1 mg kg-1. No neuromuscular blocking agents were administered. Patients were allocated randomly to four groups: gro...

journal_title：British journal of anaesthesia

authors： Davidson JA,Gillespie JA

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Muscle relaxants facilitate tracheal intubation, but they are often not used for short peripheral surgical procedures. The consequences of this practice on the upper airway are still a matter of controversy. We therefore compared the incidence of post-intubation symptoms in a randomized study comparing patie...

journal_title：British journal of anaesthesia

authors： Combes X,Andriamifidy L,Dufresne E,Suen P,Sauvat S,Scherrer E,Feiss P,Marty J,Duvaldestin P

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Single preoperative gabapentinoid (gabapentin and pregabalin) administration has been associated with respiratory depression during Phase I anaesthesia recovery. In this study, we assess for associations between chronic (home) use and perioperative administration (preoperative and postoperative) of gabapenti...

journal_title：British journal of anaesthesia

authors： Deljou A,Hedrick SJ,Portner ER,Schroeder DR,Hooten WM,Sprung J,Weingarten TN

更新日期：2018-04-01 00:00:00

abstract：:The isolated rat hepatocyte model has been used to assess the hepatotoxicity of a number of i.v. anaesthetic induction agents. Ketamine, Althesin and CCI 12923 (minaxolone) all inhibited gluconeogenesis and urea formation from alanine. There was also a decrease in the cell ATP concentration, and a dose-related increas...

journal_title：British journal of anaesthesia

authors： Sear JW,McGivan JD

更新日期：1979-08-01 00:00:00

abstract：:We have documented the changes in gas exchange, haemodynamic state and associated physiological variables which occurred after graft reperfusion in 20 patients undergoing uncomplicated orthotopic liver transplantation. Gas exchange was measured during constant ventilation using a metabolic monitor. After reperfusion, ...

journal_title：British journal of anaesthesia

authors： Walsh TS,Hopton P,Garden OJ,Lee A

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:State entropy (SE) is a newly available monitor for depth of anaesthesia. We investigated whether the relationship between predicted effect-site propofol concentration and Bispectral Index (BIS) and SE values is useful for predicting loss of verbal contact and loss of consciousness during steady-state condit...

journal_title：British journal of anaesthesia

authors： Iannuzzi M,Iannuzzi E,Rossi F,Berrino L,Chiefari M

更新日期：2005-04-01 00:00:00

abstract：:The pupils in brainstem-dead patients are classically fixed and dilated. We present a case of a brainstem-dead patient whose pupils displayed persistent asynchronous pupillary constriction and dilatation independent of external physical stimuli. Central causes for the phenomenon were excluded leaving an unexplained pe...

journal_title：British journal of anaesthesia

authors： Shlugman D,Parulekar M,Elston JS,Farmery A

更新日期：2001-05-01 00:00:00

abstract：:Most human phenotypic characteristics are determined by the interplay of environmental factors (whether external, or related to the internal milieu) with the unique genetic attributes of the individual. The same is true for predisposition to and outcome from most disease states, with acute brain injury being no except...

journal_title：British journal of anaesthesia

authors： Wilson M,Montgomery H

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:The memory effect of dexmedetomidine has not been prospectively evaluated in children. We evaluated the feasibility of measuring memory and sedation responses in children during dexmedetomidine sedation for non-painful radiological imaging studies. Secondarily, we quantified changes in memory in relation to ...

journal_title：British journal of anaesthesia

authors： Mason KP,Kelhoffer ER,Prescilla R,Mehta M,Root JC,Young VJ,Robinson F,Veselis RA

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Data on contributors to between-individual variability in overall tramadol clearance and O-demethyl tramadol (M1) formation in preterm neonates and young infants are limited. METHODS:A population pharmacokinetic analysis of tramadol and M1 was undertaken using non-linear mixed effects model. Covariate analy...

journal_title：British journal of anaesthesia

authors： Allegaert K,van den Anker JN,de Hoon JN,van Schaik RH,Debeer A,Tibboel D,Naulaers G,Anderson BJ

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Platelet inhibition is mandatory therapy after percutaneous coronary intervention (PCI). Withdrawal of oral antiplatelet agents has been linked to increased incidence of postoperative adverse cardiac events in post-PCI patients having non-cardiac surgery (NCS). There is limited knowledge of temporal changes ...

journal_title：British journal of anaesthesia

authors： Wąsowicz M,Syed S,Wijeysundera DN,Starzyk Ł,Grewal D,Ragoonanan T,Harsha P,Travis G,Carroll J,Karkouti K,Beattie WS

更新日期：2016-04-01 00:00:00

abstract：:We have conducted a randomized, double-blind comparison of 4% and 8% sevoflurane for induction of anaesthesia in unpremedicated patients aged more than 60 yr. Sevoflurane was inhaled in 50% nitrous oxide using a vital capacity breath technique, and mean, systolic and diastolic arterial pressures and heart rate were mo...

journal_title：British journal of anaesthesia

authors： Walpole R,Logan M

更新日期：1999-01-01 00:00:00

abstract：:We have evaluated the clinical utility and blood propofol concentrations produced with two different infusion regimens for propofol, given to supplement 67% nitrous oxide-morphine anaesthesia. Patients received a standardized three-step infusion of propofol based either on body weight (weight-corrected group) or on a ...

journal_title：British journal of anaesthesia

authors： Sear JW,Glen JB

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:The pulmonary artery catheter is invasive and may cause serious complications. A safe method of cardiac output (CO) measurement is needed. We have assessed the accuracy and reliability of a recently marketed self-calibrating arterial pulse contour CO monitoring system (FloTrac/Vigileo) in end-stage liver fai...

journal_title：British journal of anaesthesia

authors： Biancofiore G,Critchley LA,Lee A,Bindi L,Bisà M,Esposito M,Meacci L,Mozzo R,DeSimone P,Urbani L,Filipponi F

更新日期：2009-01-01 00:00:00

abstract：:We have determined the effect of pretreatment with mivacurium on the potency of suxamethonium and the effect of prior administration of suxamethonium on the potency of mivacurium. We studied 100 ASA I or II patients during thiopentone-fentanyl-nitrous oxide-isoflurane anaesthesia. Neuromuscular block was recorded as t...

journal_title：British journal of anaesthesia

authors： Naguib M,Abdulatif M,Selim M,al-Ghamdi A

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Clonidine is an alpha 2 adrenergic agonist with analgesic properties. This study aimed to see if the addition of clonidine to morphine when given by patient-controlled analgesia (PCA) would improve analgesia beyond the first 12 h after surgery. METHODS:Sixty patients undergoing lower abdominal surgery were ...

journal_title：British journal of anaesthesia

authors： Jeffs SA,Hall JE,Morris S

更新日期：2002-09-01 00:00:00

abstract：:Carotid endarterectomy is commonly conducted under regional (deep, superficial, intermediate, or combined) cervical plexus block, but it is not known if complication rates differ. We conducted a systematic review of published papers to assess the complication rate associated with superficial (or intermediate) and deep...

journal_title：British journal of anaesthesia

authors： Pandit JJ,Satya-Krishna R,Gration P

更新日期：2007-08-01 00:00:00

abstract：:Patients with renal failure and undergoing a cadaver renal transplant were found to have plasma concentrations of laudanosine, following the administration of a single bolus dose of atracurium 0.5 mg kg-1, higher than those found in patients without renal failure. Since laudanosine is a known central nervous system st...

journal_title：British journal of anaesthesia

authors： Fahey MR,Rupp SM,Canfell C,Fisher DM,Miller RD,Sharma M,Castagnoli K,Hennis PJ

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:The ability of the third-generation FloTrac/Vigileo software to track changes in cardiac index (CI) induced by volume expansion and norepinephrine in critically ill patients is unknown. METHODS:In subjects with circulatory failure, we administered volume expansion (20 subjects) and increased (20 subjects) o...

journal_title：British journal of anaesthesia

authors： Monnet X,Anguel N,Jozwiak M,Richard C,Teboul JL

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Brachytherapy presents the anaesthetist with unique problems. Information on anaesthesia for brachytherapy, however, is limited. The aim of this paper is to report on our experience involving a large number of brachytherapy procedures. METHODS:A retrospective analysis of records of 1622 anaesthetic procedur...

journal_title：British journal of anaesthesia

authors： Benrath J,Kozek-Langenecker S,Hüpfl M,Lierz P,Gustorff B

更新日期：2006-02-01 00:00:00

abstract：:For 6 months after renal transplant serum cholinesterase concentrations were measured in 10 patients. The value decreased in the first 15 days after operation, but was normal thereafter. Liver function tests were normal throughout the study; the cholinesterase changes were independent of immunosuppressive therapy. ...

journal_title：British journal of anaesthesia

authors： Ryan DW

更新日期：1979-09-01 00:00:00

abstract：:Patients with Munchausen's syndrome often undergo multiple surgical operations under general anaesthesia. They tend to have multiple exposures to routinely used anaesthetic agents. A patient with Munchausen's syndrome who developed an anaphylactoid reaction to thiopentone is described and the importance of obtaining p...

journal_title：British journal of anaesthesia

authors： Frater RA,Lew JK

更新日期：1987-11-01 00:00:00

abstract：:A study of core temperature monitoring during general anesthesia indicates that this can be introduced as a routine procedure in order to reduce mortality from malignant hyperpyrexia. The temperature profiles of 2410 patients are presented. Both mean rectal and mean oesophageal temperatures decreased during general an...

journal_title：British journal of anaesthesia

authors： Crocker BD,Okumura F,McCuaig DI,Denborough MA

更新日期：1980-12-01 00:00:00

abstract：:Two groups of six patients were studied during light general anaesthesia using 2% enflurane and 66% nitrous oxide in oxygen, combined with regional anaesthesia, for hernia and varicose vein surgery. The effects of 3% enflurane were compared with those of fentanyl 0.3 microgram kg-1 i.v., by measuring inspired flow, ti...

journal_title：British journal of anaesthesia

authors： Drummond GB

更新日期：1983-09-01 00:00:00