Abstract:
:Over the past decade, non-fermenting Gram-negative bacteria have emerged as important opportunistic pathogens in the increasing population of patients who are immunocompromised by their disease or medical treatment. These bacteria are assisted by their ubiquitous distribution in the environment and have a propensity for multiple, intrinsic or acquired drug resistance. The infections that they cause now pose significant problems in terms of treatment and infection control, whilst the commonly observed rapid emergence of bacterial resistance to new antimicrobial compounds raises concerns regarding the clinical lifespan of these agents. Studies are urgently required to assess whether combination therapy can improve the long-term utility of new drugs in the treatment of patients infected with non-fermenters.
journal_name
Int J Antimicrob Agentsjournal_title
International journal of antimicrobial agentsauthors
Enoch DA,Birkett CI,Ludlam HAdoi
10.1016/S0924-8579(07)72176-3subject
Has Abstractpub_date
2007-05-01 00:00:00pages
S33-41eissn
0924-8579issn
1872-7913pii
S0924-8579(07)72176-3journal_volume
29 Suppl 3pub_type
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