Multimodal analgesia for radical prostatectomy provides better analgesia and shortens hospital stay.

Abstract:

STUDY OBJECTIVE:To assess the clinical impact of paravertebral blocks (PVBs) on the immediate outcome of patients undergoing radical prostatectomy. DESIGN:Retrospective review. SETTING:Urology ward of a university medical center. MEASUREMENTS:Records of 100 consecutive patients who underwent a radical prostatectomy by the same surgeon were examined. In the first 50 patients (group 1), at surgical closure, the wound was infiltrated with 30 mL bupivacaine 0.25% and ketorolac 30 mg administered intravenously (IV). Postoperatively, patients received 15 mg ketorolac IV every 6 hours for 48 hours. Opioid (IV) patient-controlled analgesia was given overnight and thereafter, opioids were given orally as needed. The remaining 50 patients (group 2) received, in addition to the cited medication, a single preoperative oral dose of valdecoxib (40 mg) and preoperative bilateral PVBs at T10-T11-T12 using ropivacaine 0.5% (5 mL per level). Pain scores, opioid consumption, and hospital length of stay (LOS) were recorded. MAIN RESULTS:Addition of preoperative valdecoxib and bilateral PVBs was associated with significantly lower pain scores and opioid consumption. Hospital LOS was reduced from an average of 56 hours in group 1 to 47 hours in group 2. CONCLUSIONS:Preoperative bilateral PVBs and a single dose of a COX-2 inhibitor may improve immediate outcome and shorten hospital LOS after radical retropubic prostatectomy.

journal_name

J Clin Anesth

authors

Ben-David B,Swanson J,Nelson JB,Chelly JE

doi

10.1016/j.jclinane.2006.12.003

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

264-8

issue

4

eissn

0952-8180

issn

1873-4529

pii

S0952-8180(07)00074-8

journal_volume

19

pub_type

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