Abstract:
:We report noncontact optical measurement of fast transient structural changes in the crustacean nerve during action potential propagation without the need for exogenous chemicals or reflection coatings. The technique, spectral domain optical coherence tomography, provides real-time cross-sectional images of the nerve with micron-scale resolution to select a specific region for functional assessment and interferometric phase sensitivity for subnanometer-scale motion detection. Noncontact optical measurements demonstrate nanometer-scale transient movement on a 1-ms timescale associated with action potential propagation in crayfish and lobster nerves.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Akkin T,Joo C,de Boer JFdoi
10.1529/biophysj.106.091298subject
Has Abstractpub_date
2007-08-15 00:00:00pages
1347-53issue
4eissn
0006-3495issn
1542-0086pii
S0006-3495(07)71392-9journal_volume
93pub_type
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