Fibronectin gene polymorphisms are associated with the development of B-cell lymphoma in type II mixed cryoglobulinemia.

abstract：:The relationship between the tensile properties of articular cartilage and age has been investigated in vitro in the human knee joint. Specimens orientated parallel to the articular surface were excised from the superficial and deep zones of the femoral condyles of knee joints of persons in the age range from 8 to 91 ...

journal_title：Annals of the rheumatic diseases

authors： Kempson GE

更新日期：1982-10-01 00:00:00

abstract：:Four hundred and forty unrelated British Caucasoid patients with rheumatoid arthritis (RA) have been HLA typed for class I and class II antigens. Analyses of HLA antigen associations were performed on the overall group and in patient subsets selected according to particular disease parameters or sex, or both. The resu...

journal_title：Annals of the rheumatic diseases

authors： Jaraquemada D,Ollier W,Awad J,Young A,Silman A,Roitt IM,Corbett M,Hay F,Cosh JA,Maini RN

更新日期：1986-08-01 00:00:00

abstract：:The circulating levels of hyaluronate were determined in 36 patients with scleroderma and in 36 control subjects matched for age and sex. The mean serum hyaluronate concentration in patients with progressive systemic sclerosis (n = 25) was 131 +/- 67 (SD) microgram/l and significantly greater (p less than 0.001) than ...

journal_title：Annals of the rheumatic diseases

authors： Engström-Laurent A,Feltelius N,Hällgren R,Wasteson A

更新日期：1985-09-01 00:00:00

abstract：:Mild iron deficiency induced by treatment with the iron chelator desferrioxamine reduced the incidence and severity of joint inflammation associated with adjuvant disease in rats but did not alter the local primary inflammatory response or the systemic sequelae. Both rats treated with desferrioxamine and control rats ...

journal_title：Annals of the rheumatic diseases

authors： Andrews FJ,Morris CJ,Kondratowicz G,Blake DR

更新日期：1987-04-01 00:00:00

abstract：INTRODUCTION:The molecular mechanisms of syndesmophyte formation in ankylosing spondylitis (AS) are yet to be characterised. Molecules involved in bone formation such as Wnt proteins and their antagonists probably drive syndesmophyte formation in AS. METHODS:This study investigated sequential serum levels of functiona...

journal_title：Annals of the rheumatic diseases

authors： Heiland GR,Appel H,Poddubnyy D,Zwerina J,Hueber A,Haibel H,Baraliakos X,Listing J,Rudwaleit M,Schett G,Sieper J

更新日期：2012-04-01 00:00:00

abstract：:Sepsis is a severe complication of abdominal infections such as peritonitis and is associated with high mortality. Unfortunately, the molecular mechanisms controlling the development of sepsis are still incompletely understood. Interestingly, the interleukin (IL) 12 family member IL27 seems to play a key role in sepsi...

journal_title：Annals of the rheumatic diseases

authors： Neurath MF

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To study the long term effectiveness of intravenous immunoglobulin and plasmapheresis associated with prednisone and cyclophosphamide in Churg-Strauss syndrome. SUBJECTS:and methods: We studied 18 subjects with new onset Churg-Strauss syndrome. All received the "standard" treatment based on prednisone (1 mg/...

journal_title：Annals of the rheumatic diseases

authors： Danieli MG,Cappelli M,Malcangi G,Logullo F,Salvi A,Danieli G

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To determine the significance of quantitative levels of antibodies to cyclic citrullinated peptides (anti-CCP) in a population of patients with rheumatoid arthritis (RA). METHODS:A total of 241 consecutive sera from patients with RA sent from a large rheumatology clinic for laboratory testing were selected f...

journal_title：Annals of the rheumatic diseases

authors： Lee DM,Phillips R,Hagan EM,Chibnik LB,Costenbader KH,Schur PH

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:Improved DNA sequencer-aided fluorophore-assisted carbohydrate electrophoresis (DSA-FACE) technology was used to monitor the changes in the galactosylation status of serum immunoglobulins during the immune response and therapy of autoimmune arthritis. METHODS:Collagen-induced arthritis (CIA) was induced in ...

journal_title：Annals of the rheumatic diseases

authors： Van Beneden K,Coppieters K,Laroy W,De Keyser F,Hoffman IE,Van den Bosch F,Vander Cruyssen B,Drennan M,Jacques P,Rottiers P,Verbruggen G,Contreras R,Callewaert N,Elewaut D

更新日期：2009-08-01 00:00:00

abstract：:Polymorphonuclear leucocytes (PMNs), which predominate in inflammatory synovial fluid, can degrade cartilage. This was measured by a novel in vitro model; PMNs were incubated for up to one hour with 2 or 3 microns sections of cartilage and the glycosaminoglycan loss determined by microdensitometry after alcian blue st...

journal_title：Annals of the rheumatic diseases

authors： Moore AR,Iwamura H,Larbre JP,Scott DL,Willoughby DA

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To study the risk of a second malignant neoplasm (SMN) and mortality in patients with rheumatoid arthritis (RA) with a history of a primary cancer diagnosis and treated with biological disease-modifying antirheumatic drugs (bDMARD). METHODS:Among patients with RA (n=15 286) registered in the DANBIO Register ...

journal_title：Annals of the rheumatic diseases

authors： Dreyer L,Cordtz RL,Hansen IMJ,Kristensen LE,Hetland ML,Mellemkjaer L

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:Vascular endothelial growth factor (VEGF) is thought to play an important role in systemic sclerosis (SSc) pathogenesis. It was found to be upregulated in the serum and in the affected skin of scleroderma patients. However, its involvement in scleroderma lung disease is not clear. This study aimed to evaluat...

journal_title：Annals of the rheumatic diseases

authors： De Santis M,Bosello SL,Capoluongo E,Inzitari R,Peluso G,Lulli P,Zizzo G,Bocci M,Tolusso B,Zuppi C,Castagnola M,Ferraccioli G

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:To maintain and optimise the quality of care provided by health professionals in rheumatology (HPRs), adequate educational offerings are needed. This task force (TF) aimed to develop evidence-based recommendations for the generic core competences of HPRs, with specific reference to nurses, physica...

journal_title：Annals of the rheumatic diseases

authors： Edelaar L,Nikiphorou E,Fragoulis GE,Iagnocco A,Haines C,Bakkers M,Barbosa L,Cikes N,Ndosi M,Primdahl J,Prior Y,Pchelnikova P,Ritschl V,Schäfer VS,Smucrova H,Storrønning I,Testa M,Wiek D,Vliet Vlieland TPM

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Whether preradiographic lesions in knees at risk for osteoarthritis are incidental versus disease is unclear. We hypothesised, in persons without but at higher risk for knee osteoarthritis, that: 12-48 month MRI lesion status worsening is associated with 12-48 month incident radiographic osteoarthritis (obje...

journal_title：Annals of the rheumatic diseases

authors： Sharma L,Nevitt M,Hochberg M,Guermazi A,Roemer FW,Crema M,Eaton C,Jackson R,Kwoh K,Cauley J,Almagor O,Chmiel JS

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:Symptomatic knee osteoarthritis (OA) is a common disabling condition. Attention has tended to focus on the tibiofemoral joint (TFJ). However, there is evidence that the patellofemoral joint (PFJ) is involved in many cases, but its place in the sequence of development and progression of knee OA is unclear. Th...

journal_title：Annals of the rheumatic diseases

authors： Duncan R,Peat G,Thomas E,Hay EM,Croft P

更新日期：2011-11-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is highly prevalent in Malaysia, which has a mixed population of Malays, Chinese, and Indians. A quantitative enzyme linked immunosorbent assay (ELISA) was used to determine anticardiolipin antibody (aCL) levels (total immunoglobulin, IgG, and IgM) in 200 patients with SLE (164 Chine...

journal_title：Annals of the rheumatic diseases

authors： Jones HW,Ireland R,Senaldi G,Wang F,Khamashta M,Bellingham AJ,Veerapan K,Hughes GR,Vergani D

更新日期：1991-03-01 00:00:00

abstract：:Heart disease is a rare but important complication of polymyositis. Diagnosis of myocardial disease is usually based on non-specific clinical, electrocardiographic, and echocardiographic data. This paper reports a case of polymyositis with myocardial disease diagnosed by myocardial imaging with radiolabelled antibody ...

journal_title：Annals of the rheumatic diseases

authors： Le Guludec D,Lhote F,Weinmann P,Royer I,Jarrousse B,Caillat-Vigneron N,Guillevin L,Moretti JL

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVES:The aim of this pilot study was to compare clinical examination (CE) and ultrasound (US) with high field MRI (as the reference standard) for the detection of rearfoot and midtarsal joint synovitis and secondly tenosynovitis of the ankle tendons in patients with established rheumatoid arthritis (RA). METHODS...

journal_title：Annals of the rheumatic diseases

authors： Wakefield RJ,Freeston JE,O'Connor P,Reay N,Budgen A,Hensor EM,Helliwell PS,Emery P,Woodburn J

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:Few studies have addressed the natural course of, or prognostic factors for the salivary and lacrimal function in primary Sjögren syndrome (SS). Except for the early stages, glandular function has been seemingly stable, and SS A antigen (SSA) seropositivity and hypocomplementemia may predict a decline in the...

journal_title：Annals of the rheumatic diseases

authors： Haldorsen K,Moen K,Jacobsen H,Jonsson R,Brun JG

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:Regulatory T cells (Tregs) with the plasticity of producing proinflammatory cytokine IL-17 have been demonstrated under normal and pathogenic conditions. However, it remains unclear whether IL-17-producing Tregs lose their suppressive functions because of their plasticity toward Th17 in autoimmunity. The aim ...

journal_title：Annals of the rheumatic diseases

authors： Wang T,Sun X,Zhao J,Zhang J,Zhu H,Li C,Gao N,Jia Y,Xu D,Huang FP,Li N,Lu L,Li ZG

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVES:To assess the risk of losing remission, low disease activity (LDA) or radiographic progression in the case of (1) discontinuing or (2) tapering doses of biological disease-modifying antirheumatic drugs (bDMARDs) compared with continuation of the initial treatment regimen in rheumatoid arthritis (RA) patients...

journal_title：Annals of the rheumatic diseases

authors： Henaux S,Ruyssen-Witrand A,Cantagrel A,Barnetche T,Fautrel B,Filippi N,Lukas C,Raffeiner B,Rossini M,Degboé Y,Constantin A

更新日期：2018-04-01 00:00:00

abstract：:227 patients with psoriasis and various forms of arthritis have been kept under review. Psoriasis and inflammatory arthropathy was present in 168 patients, of whom 94 have been followed up for more than 10 years. An arthritis indistinguishable from rheumatoid disease was present in 78%, distal joint arthritis in 16-6%...

journal_title：Annals of the rheumatic diseases

authors： Roberts ME,Wright V,Hill AG,Mehra AC

更新日期：1976-06-01 00:00:00

abstract：OBJECTIVE:To study the value of antibodies to citrullinated proteins/peptides for predicting joint outcomes in patients with recent onset rheumatoid arthritis (RA). METHODS:191 patients with RA onset within the past year were followed up prospectively for five years. Serum samples obtained from 145 patients at baselin...

journal_title：Annals of the rheumatic diseases

authors： Meyer O,Labarre C,Dougados M,Goupille P,Cantagrel A,Dubois A,Nicaise-Roland P,Sibilia J,Combe B

更新日期：2003-02-01 00:00:00

abstract：:Sera from patients with rheumatoid arthritis (RA), patients with infectious mononucleosis (IM), and blood donors were tested by indirect immunofluorescence for the presence of antikeratin antibody (AKA), antibody to cytoskeletal intermediate filaments of prekeratin or vimentin type (AIFA) and antiperinuclear factor (A...

journal_title：Annals of the rheumatic diseases

authors： Kataaha PK,Mortazavi-Milani SM,Russell G,Holborow EJ

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVE:This randomised, double-blind, parallel-group, phase 3 study compared monotherapy with sirukumab, an anti-interleukin-6 cytokine monoclonal antibody, with adalimumab monotherapy in patients with rheumatoid arthritis (RA). METHODS:Biologic-naïve patients with active RA who were inadequate responders or were i...

journal_title：Annals of the rheumatic diseases

authors： Taylor PC,Schiff MH,Wang Q,Jiang Y,Zhuang Y,Kurrasch R,Daga S,Rao R,Tak PP,Hsu B

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:To study the reliability and construct validity of ultrasound in interphalangeal finger joints affected by erosive osteoarthritis (EOA) and non-EOA with MRI as the reference method. METHODS:252 joints were examined by ultrasound, conventional radiography and clinical examination. Ultrasound was performed us...

journal_title：Annals of the rheumatic diseases

authors： Wittoek R,Jans L,Lambrecht V,Carron P,Verstraete K,Verbruggen G

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:Annual echocardiography screening is widely used in scleroderma, but the utility of longitudinal assessment is unknown. We evaluated whether change in right ventricular systolic pressure (RVSP) was a risk factor for mortality and development of pulmonary arterial hypertension (PAH) in a cohort of scleroderma...

journal_title：Annals of the rheumatic diseases

authors： Shah AA,Chung SE,Wigley FM,Wise RA,Hummers LK

更新日期：2013-07-01 00:00:00

abstract：:HLA A, B, and C antigens were studied in 25 patients with ankylosing hyperostosis. There was no evidence of an increased frequency of any antigen in association with the condition itself. However, a high frequency of several antigens was found, reflecting the predominance of Jewish patients in the series. ...

journal_title：Annals of the rheumatic diseases

authors： Perry JD,Wolf H,Festenstein H,Storey GO

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Although natural regulatory T cells (nTregs) can suppress osteoclastogenesis, the role of TGF-β-induced CD4+Foxp3+ Tregs (iTregs) in osteoclastogenesis remains unknown. OBJECTIVE:To determine the effects of iTregs on osteoclastogenesis in vitro and on bone erosion in vivo in collagen-induced arthritis (CIA)...

journal_title：Annals of the rheumatic diseases

authors： Kong N,Lan Q,Su W,Chen M,Wang J,Yang Z,Park R,Dagliyan G,Conti PS,Brand D,Liu Z,Stohl W,Zou H,Zheng SG

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To study the association between silica exposure, separately as well as combined with smoking, and the risk of developing rheumatoid arthritis (RA) with or without the presence of antibodies against citrullinated peptide antigens (ACPA). METHODS:This Swedish population based case-control study analysed 577 i...

journal_title：Annals of the rheumatic diseases

authors： Stolt P,Yahya A,Bengtsson C,Källberg H,Rönnelid J,Lundberg I,Klareskog L,Alfredsson L,EIRA Study Group.

更新日期：2010-06-01 00:00:00