Reduced adiponectin level is associated with severity of coronary artery disease.

Abstract:

:Adipocyte-derived adiponectin has an antiatherosclerotic effect that acts independently of its antidiabetic effect. Plasma adiponectin levels are generally low in subjects with coronary artery disease. In this study, the relationship between the plasma adiponectin level and the severity of coronary artery disease, as assessed using the Gensini score, an index for the severity of coronary artery stenosis, was investigated. The subjects of the study were 104 patients (72 men and 32 women; BMI, 23.5 +/- 3.3 kg/m(2); age, 63.6 +/- 10.1 years) admitted to Tokyo University Hospital for coronary angiography. Plasma adiponectin levels were inversely correlated with the insulin resistance index HOMA-IR (P = 0.0127). The plasma adiponectin level was significantly associated with the Gensini score (P = 0.0332). After adjustment for conventional risk factors for cardiovascular diseases, the plasma adiponectin level tended to be inversely correlated with the Gensini score (P = 0.087). The measurement of plasma adiponectin levels may be useful for predicting the severity of coronary artery stenosis.

journal_name

Int Heart J

authors

Hara K,Yamauchi T,Imai Y,Manabe I,Nagai R,Kadowaki T

doi

10.1536/ihj.48.149

subject

Has Abstract

pub_date

2007-03-01 00:00:00

pages

149-53

issue

2

eissn

1349-2365

issn

1349-3299

pii

JST.JSTAGE/ihj/48.149

journal_volume

48

pub_type

杂志文章
  • Altered patterns of gene expression specific to thoracic aortic aneurysms: microarray analysis of surgically resected specimens.

    abstract::Changes in the expression levels of several genes have been described in aortic aneurysm specimens, however, the spectrum of diverse molecular alterations remains to be elucidated. We attempted to identify key molecules that modulate the pathogenesis of aortic aneurysm, using a complimentary DNA microarray carrying ap...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.46.265

    authors: Taketani T,Imai Y,Morota T,Maemura K,Morita H,Hayashi D,Yamazaki T,Nagai R,Takamoto S

    更新日期:2005-03-01 00:00:00

  • High Sensitive CRP Level Is Associated With Intermediate and High Syntax Score in Patients With Acute Coronary Syndrome.

    abstract::High sensitive C-reactive protein (hs-CRP) levels are associated with short- and long-term mortality in patients with acute coronary syndrome (ACS). We investigated whether baseline hs-CRP levels are associated with burden of coronary atherosclerosis assessed by SYNTAX score (SXScore).We enrolled 321 patients with ACS...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.14-299

    authors: Karadeniz M,Duran M,Akyel A,Yarlıoğlueş M,Öcek AH,Çelik İE,Kılıç A,Yalcin AA,Ergün G,Murat SN

    更新日期:2015-01-01 00:00:00

  • Heart is the Target Organ of Endogenous Cardiac Natriuretic Peptides.

    abstract::This study aimed to evaluate whether the heart is the target organ of endogenous atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in patients with heart failure (HF) with reduced ejection fraction (HFrEF).We measured the plasma levels of cyclic guanosine monophosphate (cGMP), which is a second mess...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.19-379

    authors: Tsutamoto T,Sakai H,Yamamoto T,Nakagawa Y

    更新日期:2020-01-31 00:00:00

  • Inverse relationship between adiponectin levels and subclinical carotid atherosclerosis in patients undergoing coronary artery bypass grafting.

    abstract::The purpose of this study was to examine the relation between adiponectin levels and subclinical carotid atherosclerosis in patients undergoing coronary artery bypass grafting (CABG). Serum concentrations of adiponectin and carotid intima/media thickness (IMT) were measured in 84 consecutive patients who underwent CAB...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.47.855

    authors: Kiris I,Tekin I,Yesildag A,Vural H,Oyar O,Sirin B,Okutan H,Ibrisim E

    更新日期:2006-11-01 00:00:00

  • Single Femoral Venous Drainage Versus Both Vena Cava Drainage in Isolated Repeat Tricuspid Valve Surgery.

    abstract::To assess the potential advantages of minimally invasive surgery using a single femoral venous drainage method versus femoral venous and superior vena cava or jugular venous drainage method during repeat tricuspid valve surgery.From January 2010 to December 2016, 50 repeat tricuspid valve procedures were performed usi...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.17-169

    authors: Peng R,Shi H,Ba J,Wang C

    更新日期:2018-05-30 00:00:00

  • Clinical Manifestation, Timing Course, Precipitating Factors, and Protective Factors of Ventricular Free Wall Rupture Following ST-Segment Elevation Myocardial Infarction.

    abstract::Ventricular free wall rupture (FWR) is a catastrophic complication of that occurs after acute myocardial infarction (AMI), and at present, its clinical characteristics are unclear. We analyzed a total of 6,712 consecutive patients who presented with ST-segment elevation myocardial infarction (STEMI), and 78 patients w...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.19-541

    authors: Gong W,Shi H,Yan M,Yan Y,Wang X,Li S,He X,Nie S

    更新日期:2020-07-30 00:00:00

  • Gender-Related Association of Serum Uric Acid Levels with Premature Ventricular Contraction.

    abstract::In this study, we aim to investigate the association of serum uric acid (SUA) with the prevalence of premature ventricular contraction (PVC). The relationship between SUA and the prevalence of PVC in 98,965 subjects (79,034 male subjects, mean age: 51.9 ± 12.6 years old) in the Kailuan cohort study (n = 101,510, age r...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.17-474

    authors: Chen Y,Wu S,Li W,Wang B,Lv H,Yang X,Khalid BW,Yin X,Xia Y

    更新日期:2018-11-28 00:00:00

  • The Clinical Efficacy of Endothelin Receptor Antagonists in Patients with Pulmonary Arterial Hypertension.

    abstract::Therapeutic strategies for pulmonary arterial hypertension (PAH) have made remarkable progress over the last two decades. Currently, 3 types of drugs can be used to treat PAH; prostacyclins, phosphodiesterase 5 inhibitors, and endothelin receptor antagonists (ERA). In Japan, the first generation ERA bosentan was reimb...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.20-173

    authors: Maki H,Hara T,Tsuji M,Saito A,Minatsuki S,Inaba T,Amiya E,Hosoya Y,Hatano M,Morita H,Yao A,Kinugawa K,Komuro I

    更新日期:2020-01-01 00:00:00

  • Correlation Between Arteriosclerosis and Periodontal Condition Assessed by Lactoferrin and α1-Antitrypsin Levels in Gingival Crevicular Fluid.

    abstract::Patients with periodontal disease exhibit exacerbated atherosclerosis, aortic stiffness, or vascular endothelial dysfunction. However, in a recent scientific statement, the American Heart Association noted that neither has periodontal disease been proven to cause atherosclerotic vascular disease nor has the treatment ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.15-218

    authors: Hayashi S,Yamada H,Fukui M,Ito HO,Sata M

    更新日期:2015-01-01 00:00:00

  • Impact of Compound Hypertonic Saline Solution on Decompensated Heart Failure.

    abstract::The aim of the present study was to evaluate the effects of hypertonic saline solution (C-HSS) with high dose furosemide on hospitalization time, readmission, and mortality in patients with New York Heart Association (NYHA) class III heart failure.Decompensated heart failure patients (NYHA III) with chronic ischemic o...

    journal_title:International heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1536/ihj.16-313

    authors: Wan Y,Li L,Niu H,Ma X,Yang J,Yuan C,Mu G,Zhang J

    更新日期:2017-08-03 00:00:00

  • Transradial percutaneous coronary intervention for acute myocardial infarction reduces CCU stay in patients 80 or older.

    abstract::Transradial percutaneous coronary intervention (PCI), which is less invasive than transfemoral PCI, may facilitate early rehabilitation of patients with acute myocardial infarction (AMI). The aim of our study was to investigate whether transradial PCI is associated with a shorter coronary care unit (CCU) stay in very ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.53.79

    authors: Jinnouchi H,Sakakura K,Wada H,Kubo N,Sugawara Y,Nakamura T,Funayama H,Ako J,Momomura S

    更新日期:2012-01-01 00:00:00

  • Transradial approach percutaneous coronary interventions in an out-patient clinic.

    abstract::Same-day discharge transradial percutaneous coronary intervention (TRI) has been reported to be safe and feasible in Western countries. However, Asia has not produced any reports related to this matter. The present study explored the safety and feasibility of patients with indications for TR coronary angiography and a...

    journal_title:International heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1536/ihj.51.371

    authors: Chung WJ,Fang HY,Tsai TH,Yang CH,Chen CJ,Chen SM,Cheng CI,Fang CY,Hsieh YK,Hang CL,Yip HK,Wu CJ

    更新日期:2010-01-01 00:00:00

  • Implant Characteristics of Quadripolar and Bipolar Left Ventricular Leads for Cardiac Resynchronization Therapy.

    abstract::Several studies have reported that the left ventricular (LV) lead implant success rate ranges between 88.0% and 92.4%. Coronary venous anatomy differs among patients thus, necessitating multiple types of leads. To date, the implant success rate among Japanese patients utilizing a pre-specified family LV leads (includi...

    journal_title:International heart journal

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1536/ihj.17-442

    authors: Ando K,Kanda S,Miura F,Ashikaga K,Ehara N,Sakai Y,Furukawa T,Yoshimura H,Adachi K

    更新日期:2018-09-26 00:00:00

  • Sarpogrelate hydrochloride decreases cardio-ankle vascular index accompanied by increased serum lipoprotein lipase mass in type 2 diabetic patients.

    abstract::The 5-hydroxytryptamine2A receptor antagonist sarpogrelate hydrochloride exerts its effect not only by inhibition of platelet aggregation, but also by some pleiotropic effects. We have reported that a low serum lipoprotein lipase (LPL) mass level reflects insulin resistance and may be a risk factor for atherosclerotic...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.13-377

    authors: Nagayama D,Ohira M,Saiki A,Shirai K,Tatsuno I

    更新日期:2014-01-01 00:00:00

  • Basic echocardiographic features of patients with latent left ventricular outflow tract obstruction without left ventricular hypertrophy.

    abstract::Left ventricular outflow tract obstruction (LVOTO) is commonly observed in patients with hypertrophic cardiomyopathy (HCM) or left ventricular hypertrophy (LVH). While some patients develop LVOTO at rest, it can also be provoked by physical exertion, and hence termed latent LVOTO (L-LVOTO). Recent reports demonstrated...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.53.230

    authors: Semba H,Sawada H,Uejima T,Takeda N,Soma K,Abe H,Yamashita T,Nagai R

    更新日期:2012-01-01 00:00:00

  • Impact of mild to moderate renal dysfunction on left ventricular relaxation function and prognosis in ambulatory patients with nonischemic dilated cardiomyopathy.

    abstract::The relationship between mild-to-moderate renal dysfunction and cardiac diastolic dysfunction and cardiac events in patients with nonischemic dilated cardiomyopathy (NDCM) has not been fully elucidated. The aim of this study was to investigate the relationship between renal and cardiac function, as well as clinical ou...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.52.366

    authors: Ohshima K,Hirashiki A,Cheng XW,Hayashi M,Hayashi D,Okumura T,Sakakibara M,Funahashi H,Ohshima S,Murohara T

    更新日期:2011-01-01 00:00:00

  • Atorvastatin prevents left ventricular remodeling in spontaneously hypertensive rats.

    abstract::Statins improve left ventricular (LV) remodeling in spontaneously hypertensive rats (SHRs). This study was designed to investigate the effects of atorvastatin administered in the early stage on LV remodeling in SHRs, and to explore the underlying mechanisms.Sixteen male 8-week-old SHRs were randomized to receive disti...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.51.426

    authors: Zhao XY,Li L,Zhang JY,Liu GQ,Chen YL,Yang PL,Liu RY

    更新日期:2010-01-01 00:00:00

  • Temperature-controlled cooled-tip radiofrequency ablation in left ventricular myocardium.

    abstract::Steam pop and intramural charring have been reported during cooled-tip radiofrequency catheter ablation (RFCA). We studied the feasibility of temperature-controlled cooled-tip RFCA in the canine heart.An internally cooled ablation catheter was inserted into the left ventricle. A custom-made radiofrequency (RF) generat...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.51.193

    authors: Watanabe I,Nuo M,Okumura Y,Ohkubo K,Ashino S,Kofune M,Kofune T,Nakai T,Kasamaki Y,Hirayama A

    更新日期:2010-05-01 00:00:00

  • Mechanism of pressure-overload right ventricular hypertrophy in infant rabbits.

    abstract::Although pressure-overload right ventricular hypertrophy is a long-term risk in some congenital heart diseases such as tetralogy of Fallot, how it develops is unclear. The aim of this study was to investigate the mechanism of development of this right ventricular heart failure.Pulmonary artery banding in 10-day-old ra...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.52.56

    authors: Minegishi S,Kitahori K,Murakami A,Ono M

    更新日期:2011-01-01 00:00:00

  • Long-term coronary endothelial function after zotarolimus-eluting stent implantation. A 9 month comparison between zotarolimus-eluting and sirolimus-eluting stents.

    abstract::Implantation of a paclitaxel- or sirolimus-eluting stent (SES) may be associated with endothelial dysfunction. In the present study, we compared coronary endothelial function after zotarolimus-eluting stent (ZES) implantation to that after SES implantation. Patients who had one stent implantation for a single lesion i...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.49.639

    authors: Shin DI,Seung KB,Kim PJ,Chang K,Choi JK,Jeon DS,Kim MJ,Lee MY,Chung WS

    更新日期:2008-11-01 00:00:00

  • Comparison of Archival Angiographic Findings in Patients Later Developing Acute Coronary Syndrome or Stable Angina.

    abstract::Acute coronary syndrome (ACS) can develop in patients with mildly to moderately stenotic lesions. However, the angiographic characteristics of lesions in patients who will later develop ACS have not been systematically investigated. For this reason, we examined the earlier angiographic findings of such patients in a r...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.19-601

    authors: Yamaya S,Morino Y,Taguchi Y,Ninomiya R,Ishida M,Fusazaki T,Itoh T,Kimura T

    更新日期:2020-05-30 00:00:00

  • Therapeutic vaccines for hypertension and dyslipidemia.

    abstract::Vaccines are commonly used as a preventive medicine for infectious diseases worldwide, however, clinical trials on an amyloid beta vaccine for Alzheimer's disease represents a new concept in the field of vaccinations. Several recent studies indicate the potential of therapeutic vaccines as well as classical vaccines a...

    journal_title:International heart journal

    pub_type: 杂志文章,评审

    doi:10.1536/ihj.13-383

    authors: Nakagami H,Koriyama H,Morishita R

    更新日期:2014-01-01 00:00:00

  • Electrophysiological properties of the atrium after cardioversion of chronic atrial fibrillation: relation to the plasma brain natriuretic peptide level.

    abstract:BACKGROUND:Brain natriuretic peptide (BNP) level has been shown to increase in patients with chronic atrial fibrillation (CAF) without overt heart failure (HF). Although atrial electrical remodeling associated with CAF has been described, little is known about the effects of the BNP level on the electrophysiological pr...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.48.485

    authors: Okumura Y,Watanabe I,Ashino S,Kofune M,Takagi Y,Kofune T,Okubo K,Hashimoto K,Shindo A,Sugimura H,Nakai T,Kasamaki Y,Saito S

    更新日期:2007-07-01 00:00:00

  • Risk Scoring System for Prognosis Estimation of Multivessel Disease Among Patients with ST-Segment Elevation Myocardial Infarction.

    abstract::Multivessel disease (MVD) is an independent risk factor for poor prognosis in acute myocardial infarction patients. Although several global risk scoring systems (RSS) are in use in clinical practice, there is no dedicated RSS for MVD in ST-segment elevation myocardial infarction (STEMI). The primary objective of this ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.17-337

    authors: Ryu KS,Bae JW,Jeong MH,Cho MC,Ryu KH,and other Korea Acute Myocardial Infarction Registry Investigators.

    更新日期:2019-05-30 00:00:00

  • Errata: Polysaccharides from Enteromorpha Prolifera Ameliorate Acute Myocardial Infarction in Vitro and in Vivo via Up-Regulating HIF-1α.

    abstract::An error appeared in the article entitled "Polysaccharides from Enteromorpha Prolifera Ameliorate Acute Myocardial Infarction in Vitro and in Vivo via Up-Regulating HIF-1α" by Zongqiu Wang, Zhihua Zhang, Jing Zhao, Chunming Yong, and Yongjun Mao (Vol. 60, No. 4, 964-973, 2019).The second affiliation of the authors on ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.60-5_Erratum

    authors: Wang Z,Zhang Z,Zhao J,Yong C,Mao Y

    更新日期:2019-01-01 00:00:00

  • Revascularization of malignant coronary instent restenosis resulting from Takayasu's arteritis using sirolimus-eluting stents.

    abstract::A 37 year-old female who had suffered from arteritis for 20 years underwent a Bentall operation. Since severe stenosis was observed in her left main coronary artery (LMCA) the following year, a minimally invasive direct coronary artery bypass (MIDCAB) operation was performed. Unfortunately, she again complained of ang...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.47.795

    authors: Sakai H,Oyama N,Kishimoto N,Takahashi M,Urasawa K,Tsutsui H

    更新日期:2006-09-01 00:00:00

  • Symptoms of atrial fibrillation in patients with and without subsequent permanent atrial fibrillation based on a retrospective questionnaire survey.

    abstract::The aim of the present study was to determine whether symptoms of atrial fibrillation (AF) differ between patients with and without subsequent permanent AF. Sixty-four patients (68 +/- 10 years old, 45 males) were recruited. AF follow-up was started at the age of 61 +/- 10 years and accomplished in a median period of ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.51.242

    authors: Kawara T,Narumi J,Hirao K,Kasuya K,Kawabata M,Tojo N,Isobe M,Matsuura M

    更新日期:2010-07-01 00:00:00

  • Circadian variation of acute aortic dissection.

    abstract::Acute aortic dissection (AAD) is a life-threatening cardiovascular disease with high mortality. Hypertension is a well known risk factor of AAD. There have been previous reports about the association between circadian variation of blood pressure (BP) and cardiovascular events. However, little is known about the associ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.14-328

    authors: Seguchi M,Wada H,Sakakura K,Nakagawa T,Ibe T,Ikeda N,Sugawara Y,Ako J,Momomura S

    更新日期:2015-05-13 00:00:00

  • Electrical stimulation of skeletal muscles. An alternative to aerobic exercise training in patients with chronic heart failure?

    abstract::The aim of this study was to investigate whether electrical stimulation of skeletal muscles could represent a rehabilitation alternative for patients with chronic heart failure (CHF). Thirty patients with CHF and NYHA class II-III were randomly assigned to a rehabilitation program using either electrical stimulation o...

    journal_title:International heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1536/ihj.47.441

    authors: Dobsák P,Nováková M,Fiser B,Siegelová J,Balcárková P,Spinarová L,Vítovec J,Minami N,Nagasaka M,Kohzuki M,Yambe T,Imachi K,Nitta S,Eicher JC,Wolf JE

    更新日期:2006-05-01 00:00:00

  • Bilateral percutaneous ulnar artery approach for retrograde chronic total occlusion intervention.

    abstract::The transradial approach for coronary diagnostic and therapeutic interventions is a well-established, safe, and effective technique that has shown a success rate comparable to that of the transfemoral approach for chronic total occlusion (CTO) with less access site complications. Recently, the transulnar approach was ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.51.137

    authors: Hussein H,Gan HW,Fang HY,Wu CJ

    更新日期:2010-03-01 00:00:00