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Sulpiride induced torsade de pointes.

Abstract：

:Antipsychotic agents are known to be associated with a long QT interval and torsade de pointes. We report a 69 year old female who suffered from a syncopal attack at a psychiatric hospital and was referred to our center. Torsade de pointes with a long QT interval (QTc=680 ms) was observed on the 12 lead ECG in the emergency department and intensive care unit. A careful drug history revealed that sulpiride was the culprit agent. After stopping the medication, the QT interval returned to normal (420 ms). The patients taking sulpiride should be closely monitored, especially when it is used in combination with other antidepressant agents.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Huang BH,Hsia CP,Chen CY

doi

10.1016/j.ijcard.2007.01.060

subject

Has Abstract

pub_date

2007-06-12 00:00:00

pages

e100-2

issue

3

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(07)00459-7

journal_volume

118

pub_type

信件

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