Abstract:
:Alzheimer's disease (AD) is a degenerative disease which causes serious cognitive decline. Studies suggest that effective treatments for AD may be aided by the detection of the disease in its early stages, prior to extensive neuronal degeneration. In this paper, we propose a set of novel techniques which could help to perform this task, and present the results of experiments conducted to evaluate these approaches. The challenge is to discriminate between spontaneous EEG recordings from two groups of subjects: one afflicted with mild cognitive impairment and eventual AD and the other an age-matched control group. The classification results obtained indicate that the proposed methods are promising additions to the existing tools for detection of AD, though further research and experimentation with larger datasets is required to verify their effectiveness.
journal_name
Physiol Measjournal_title
Physiological measurementauthors
Woon WL,Cichocki A,Vialatte F,Musha Tdoi
10.1088/0967-3334/28/4/001subject
Has Abstractpub_date
2007-04-01 00:00:00pages
335-47issue
4eissn
0967-3334issn
1361-6579pii
S0967-3334(07)34689-3journal_volume
28pub_type
杂志文章abstract::Heart rate variability (HRV) is often analysed using short-term studies. Our objective was to compare two of them in a group of diabetic patients (reduced HRV) and in a control group. From the same 10 min surface electrocardiogram (ECG) two recordings were obtained. In one of them the whole signal was acquired through...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/25/6/n01
更新日期:2004-12-01 00:00:00
abstract::Using a primary coil that induces eddy currents in a volume conductor, and a pair of secondary coils configured to form a differential transformer, it is possible to measure the conductivity of a volume conductor by the magnetic fields of the induced eddy currents. This method is especially favourable for measuring im...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/14/4/007
更新日期:1993-11-01 00:00:00
abstract::Electrical impedance tomography (EIT) measures the conductivity distribution within an object based on the current applied and voltage measured at surface electrodes. Thus, EIT images are sensitive to electrode properties (i.e. contact impedance, electrode area and boundary shape under the electrode). While some of th...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/7/S02
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:This paper aims to present how physiological signals can be processed based on wavelet decomposition to calculate multiple physiological parameters in real-time on an embedded platform. APPROACH:An ECG and PPG are decomposed to the appropriate scale based on a quadratic spline wavelet base in order to obtain...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab6f52
更新日期:2020-03-06 00:00:00
abstract::In order to detect minute amounts of glucose in diluted urine, we applied the Raman spectroscopy method. To simulate abnormal diluted urine in a toilet bowl, we diluted normal urine ten-fold with water and added glucose up to 8 mg dl(-1). Data were collected using a low-resolution Raman spectrometer that was preproces...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/5/011
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVE:In this research, we introduce a new methodology for atrial fibrillation (AF) diagnosis during sleep in a large population sample at risk of sleep-disordered breathing. APPROACH:The approach leverages digital biomarkers and recent advances in machine learning (ML) for mass AF diagnosis from overnight-hours o...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/abb8bf
更新日期:2020-11-06 00:00:00
abstract::The objective of this study was to adapt a novel near-infrared diffuse correlation spectroscopy (DCS) flow-oximeter for simultaneous and continuous monitoring of relative changes in cerebral blood flow (rCBF) and cerebral oxygenation (i.e. oxygenated/deoxygenated/total hemoglobin concentration: Δ[HbO2]/Δ[Hb]/ΔTHC) dur...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/10/2135
更新日期:2014-10-01 00:00:00
abstract::The recently-introduced technique of detrended fluctuation analysis (DFA) for heart-rate variability appears to yield improved prognostic power in cardiovascular disease through calculation of the fractal scaling exponent alpha. However, the physiological meaning of alpha remains unclear. In DFA, the signal is segment...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/23/2/314
更新日期:2002-05-01 00:00:00
abstract::The activPAL™ activity monitor has potential for use in youth with Cerebral Palsy (CP) as it has demonstrated acceptable validity for the assessment of sedentary and physical activity in other populations. This study determined the validity of the activPAL™ activity monitor for the measurement of sitting, standing, wa...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/11/2307
更新日期:2014-11-01 00:00:00
abstract::Easily applicable and inexpensive water-specific techniques to evaluate local oedema, swollen tissue problems and fluid retention in humans are not available. In the present investigation a recently constructed non-invasive device for a local measurement of changes in tissue water in human skin and subcutaneous fat (S...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/25/2/004
更新日期:2004-04-01 00:00:00
abstract::A new method to image and quantify intra-abdominal haemorrhage using electrical impedance tomography (EIT) was tested in vivo. Supine peritoneal dialysis patients were monitored using an 8-electrode hemiarray placed on the anterior abdomen. EIT measurements were recorded using the EPack II data acquisition system befo...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/2/001
更新日期:2011-02-01 00:00:00
abstract::A coordinated study of the dispersal of water between the various body compartments (stomach and gut, blood stream and tissue) and the similar dispersal kinetics of ethanol and its metabolism has been carried out involving two healthy volunteers using flowing afterglow mass spectrometry, FA-MS, and selected ion flow t...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/26/4/011
更新日期:2005-08-01 00:00:00
abstract::The specific heat capacity of tissue is a critical parameter for thermal therapies that act over a long period of time. It is also critical for thermoacoustic signal generation. We present ex vivo measurements of specific heat capacity performed by a dual-pin probe with tight temperature control of the specimen. One 3...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/11/N02
更新日期:2011-11-01 00:00:00
abstract::Capnography is a continuous and noninvasive method for carbon dioxide (CO2) measurement, and it has become the standard of care for basic respiratory monitoring for intubated patients in the intensive care unit. In addition, it has been used to adjust ventilatory parameters during mechanical ventilation (MV). However,...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/2/231
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To validate the accuracy of the Oura ring in the quantification of resting heart rate (HR) and heart rate variability (HRV). BACKGROUND:Wearable devices have become comfortable, lightweight, and technologically advanced for assessing health behavior. As an example, the novel Oura ring integrates daily physic...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab840a
更新日期:2020-05-07 00:00:00
abstract::In this paper we present the T-SCAN technology and its use as a diagnostic tool for breast cancer detection. We show, using theoretical models with simplified geometries, that displaying planar two-dimensional maps of the currents detected at the breast's surface relate to the electric field distribution within the br...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/22/1/301
更新日期:2001-02-01 00:00:00
abstract::Remote sensing of the reflectance photoplethysmogram using a video camera typically positioned 1 m away from the patient's face is a promising method for monitoring the vital signs of patients without attaching any electrodes or sensors to them. Most of the papers in the literature on non-contact vital sign monitoring...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/5/807
更新日期:2014-05-01 00:00:00
abstract::The back-projected independent components (BICs) of single-trial, auditory P300 and contingent negative variation (CNV) evoked potentials (EPs) were derived using independent component analysis (ICA) and cluster analysis. The method was tested in simulation including a study of the electric dipole equivalents of the s...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/8/001
更新日期:2007-08-01 00:00:00
abstract::Peripheral vasculature disease is strongly correlated with cardiovascular-associated mortality. Monitoring circulation health, especially in the peripheral limbs, is vital to detecting clinically significant disease at a stage when it can still be addressed through medical intervention. Electrical impedance tomography...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/29/3/006
更新日期:2008-03-01 00:00:00
abstract::False intensive care unit (ICU) alarms induce stress in both patients and clinical staff and decrease the quality of care, thus significantly increasing both the hospital recovery time and rehospitalization rates. In the PhysioNet/CinC Challenge 2015 for reducing false arrhythmia alarms in ICU bedside monitor data, th...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/8/1273
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Characteristic impedance (Zc) is an important component in the theory of hemodynamics. It is a commonly used metric of proximal arterial stiffness and pulse wave velocity. Calculated using simultaneously measured dynamic pressure and flow data, estimates of characteristic impedance can be obtained using metho...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aa9d60
更新日期:2018-01-31 00:00:00
abstract::Obesity is a major health issue in both developed and developing countries. The balance between energy intake and exercise is important, and measurements of both energy intake and energy expenditure are required. Many studies have attempted to monitor energy intake via wearable technology, but no standard methods have...
journal_title:Physiological measurement
pub_type: 杂志文章,评审
doi:10.1088/1361-6579/ab3827
更新日期:2019-09-03 00:00:00
abstract:OBJECTIVE:To investigate the feasibility of the detection of brief orofacial pain sensations from easily recordable physiological signals by means of machine learning techniques. APPROACH:A total of 47 subjects underwent periodontal probing and indicated each instance of pain perception by means of a push button. Simu...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aadf0c
更新日期:2018-09-27 00:00:00
abstract::High-frequency percussive ventilation (HFPV) may be defined as flow-regulated time-cycled ventilation that creates controlled pressure and delivers a series of high-frequency subtidal volumes in combination with low-frequency breathing cycles. In recent years, the usefulness of HFPV has been clinically assessed as an ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/6/002
更新日期:2011-06-01 00:00:00
abstract::Body surface potential maps recorded during catheter pace mapping can facilitate the localization of the site of origin of ventricular tachycardia. In this study, we investigated the value of a realistic computer model of the human ventricular myocardium in generating body surface potential maps as templates for ident...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/18/4/010
更新日期:1997-11-01 00:00:00
abstract::This study compared sitting time measured by a questionnaire (International Physical Activity Questionnaire; IPAQ) with concurrently measured objective sitting time from an accelerometer-based measure of thigh inclination (activPAL).Adults (n = 69), wore an activPAL for a week, and then completed the long-form 7 d rec...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/11/2319
更新日期:2014-11-01 00:00:00
abstract::The wrist is increasingly being used as the preferred site for objectively assessing physical activity but the relative accuracy of processing methods for wrist data has not been determined. OBJECTIVE:This study evaluates the validity of four processing methods for wrist-worn ActiGraph (AG) data against energy expend...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aa6d00
更新日期:2017-06-01 00:00:00
abstract::In recent AASM practice, parameter actimetry is cited to measure total sleep time in obstructive sleep apnoea patients, when polysomnography is not available. An actigraph was therefore compared to polysomnographic data in 28 subjects with known sleep disordered breathing. Total sleep time (TST), sleep period time (SP...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/31/12/005
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:The healing of wounds is critical in protecting the human body against environmental factors. The mechanisms involving protein expression during this complex physiological process have not been fully elucidated. APPROACH:Here, we use reverse-phase protein microarrays (RPPA) involving 94 phosphoproteins to st...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aaee19
更新日期:2018-12-07 00:00:00
abstract:OBJECTIVE:Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease characterized by excessive deposition of collagen and associated stiffening of lung tissue. While it is known that inflammation and dysfunction of fibroblasts are involved in disease development, it remains poorly understood how cells and ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aaca86
更新日期:2018-06-28 00:00:00