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Synthesis and insecticidal activity of chromanone and chromone analogues of diacylhydrazines.

Abstract：

:Diacylhydrazine derivatives have been identified as one of the most important insect growth regulators. A variety of diacylhydrazine derivatives were designed and synthesized in recent years due to their unique action mechanism, simple structure, and environmental benign character. This paper describes the molecular design, synthesis, and insecticidal activities of a series of chromanone and chromone analogues of diacylhydrazine derivatives. The preliminary bioassay showed that some of the chromanone analogues exhibited good insecticidal activity against Mythima separata at the dosage of 500 mg L-1. The present work demonstrated that replacement of the chroman ring of ANS-118, a commercial insecticide, with chromanone moiety could result in new compounds with high potent insecticidal activity.

journal_name

Bioorg Med Chem

journal_title

Bioorganic & medicinal chemistry

authors

Zhao PL,Li J,Yang GF

doi

10.1016/j.bmc.2007.01.008

subject

Has Abstract

pub_date

2007-03-01 00:00:00

pages

1888-95

issue

5

eissn

0968-0896

issn

1464-3391

pii

S0968-0896(07)00023-5

journal_volume

15

pub_type

杂志文章

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