The association between the proximal extension of the clot and the severity of pulmonary embolism (PE): a proposal for a new radiological score for PE.

abstract：:We report two cases of fulminant hepatic failure in HIV-1-infected patients treated with didanosine (ddI). Clinical manifestations including vomiting, diarrhoea and dyspnoea were identical in both cases. Biological data mainly revealed hepatic failure and lactic acidosis. Histological examination of liver biopsies sho...

journal_title：Journal of internal medicine

authors： Bissuel F,Bruneel F,Habersetzer F,Chassard D,Cotte L,Chevallier M,Bernuau J,Lucet JC,Trepo C

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:Patients undergoing bariatric surgery present long-term metabolic improvements and reduced type 2 diabetes risk, despite long-term weight regain. We hypothesized that part of these protective effects could be linked to altered gene expression in white adipose tissue (WAT). METHODS:Transcriptomic profiling by...

journal_title：Journal of internal medicine

authors： Kerr AG,Andersson DP,Rydén M,Arner P,Dahlman I

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:The major aim of this study was to compare various aspects of carbohydrate, insulin, and lipoprotein metabolism, serum uric acid concentration, and blood pressure in normal subjects stratified on the basis of both plasma insulin concentration and degree of obesity. The hypothesis to be tested was that hyperin...

journal_title：Journal of internal medicine

authors： Zavaroni I,Bonini L,Fantuzzi M,Dall'Aglio E,Passeri M,Reaven GM

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:To assess the long-term prognostic values of baseline demographic data, occurrence of vectorcardiographic signs of reperfusion, left ventricular function and coronary angiographic features. DESIGN:Longitudinal study of morbidity and mortality. SETTING:Coronary care unit at Danderyd Hospital, Stockholm, Swe...

journal_title：Journal of internal medicine

authors： Strandberg LE,Ericsson CG,O'Konor ML,Bergstrand L,Lundin P,Rehnqvist N,Tornvall P

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVES:Studies on extracranial carotid atherosclerosis have predominately been undertaken on middle-aged subjects. This study examines the prevalence of extracranial carotid atherosclerosis, its relation to vascular risk factors and its significance for survival in elderly subjects. DESIGN:Population-based cross-s...

journal_title：Journal of internal medicine

authors： Hillen T,Nieczaj R,Münzberg H,Schaub R,Borchelt M,Steinhagen-Thiessen E

更新日期：2000-06-01 00:00:00

abstract：:This review discusses the interplay between multimorbidity (i.e. co-occurrence of more than one chronic health condition in an individual) and functional impairment (i.e. limitations in mobility, strength or cognition that may eventually hamper a person's ability to perform everyday tasks). On the one hand, diseases b...

journal_title：Journal of internal medicine

authors： Calderón-Larrañaga A,Vetrano DL,Ferrucci L,Mercer SW,Marengoni A,Onder G,Eriksdotter M,Fratiglioni L

更新日期：2019-03-01 00:00:00

abstract：:We investigated skeletal involvement in five male and two female patients with ochronosis, aged 26-82 years. The main parameters of mineral metabolism, together with biochemical markers of bone resorption (urinary N-telopeptides of type I collagen) and formation (serum bone isoenzyme of alkaline phosphatase and serum ...

journal_title：Journal of internal medicine

authors： Aliberti G,Pulignano I,Schiappoli A,Minisola S,Romagnoli E,Proietta M

更新日期：2003-09-01 00:00:00

abstract：:In its classic hormonal role, erythropoietin (EPO) is produced by the kidney and regulates the number of erythrocytes within the circulation to provide adequate tissue oxygenation. EPO also mediates other effects directed towards optimizing oxygen delivery to tissues, e.g. modulating regional blood flow and reducing b...

journal_title：Journal of internal medicine

authors： Brines M,Cerami A

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:P2X7 receptor (P2X7R), trigger of acute inflammatory responses via the NLRP3 inflammasome, is hyperfunctioning in patients with Sjögren's syndrome (SS), where it stimulates IL-18 production. Some patients with SS develop a mucosa-associated lymphoid tissue non-Hodgkin's lymphoma (MALT-NHL). OBJECTIVES:To pr...

journal_title：Journal of internal medicine

authors： Baldini C,Santini E,Rossi C,Donati V,Solini A

更新日期：2017-08-01 00:00:00

abstract：:The aim of the present study was to determine the incidence of malignant disease (MD) in adult patients with nephrotic syndrome (NS). Eighty-eight consecutive patients (38 females; 50 males; mean age 47 years; range 15-86) seen in a renal clinic in a 13-year period with NS were studied. Eight of the patients had or de...

journal_title：Journal of internal medicine

authors： Lund L,Jacobsen BA,Schmidt EB

更新日期：1989-09-01 00:00:00

abstract：:Breast cancer is not only increasing in the west but also particularly rapidly in eastern countries where traditionally the incidence has been low. The rise in incidence is mainly related to changes in reproductive patterns and lifestyle. These trends could potentially be reversed by defining women at greatest risk an...

journal_title：Journal of internal medicine

authors： Howell A,Astley S,Warwick J,Stavrinos P,Sahin S,Ingham S,McBurney H,Eckersley B,Harvie M,Wilson M,Beetles U,Warren R,Hufton A,Sergeant J,Newman W,Buchan I,Cuzick J,Evans DG

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In the past two decades, an increasing number of nationwide, Swedish Healthcare Quality Registries (QRs) focusing on specific disorders have been initiated, mostly by physicians. Here, we describe the purpose, organization, variables, coverage and completeness of 103 Swedish QRs. METHODS:From...

journal_title：Journal of internal medicine

authors： Emilsson L,Lindahl B,Köster M,Lambe M,Ludvigsson JF

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Addition of assessment of comorbid diseases ('D') and oxygen saturation ('S') to the CRB-65 score has been recommended to improve its accuracy for risk stratification in community-acquired pneumonia (CAP). The aim of this study was to validate the resulting DS-CRB-65 score in a large cohort of patients with ...

journal_title：Journal of internal medicine

authors： Kolditz M,Ewig S,Schütte H,Suttorp N,Welte T,Rohde G,CAPNETZ study group.

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:Combinations of inhaled corticosteroids (ICSs) and long-acting β2 -agonists (LABAs) are recommended for patients with moderate and severe chronic obstructive pulmonary disease (COPD). However, it is not known whether different fixed combinations are equally effective. The aim of this study was to investigate...

journal_title：Journal of internal medicine

authors： Larsson K,Janson C,Lisspers K,Jørgensen L,Stratelis G,Telg G,Ställberg B,Johansson G

更新日期：2013-06-01 00:00:00

abstract：:Current strategies for prevention of cardiovascular disease focus on risk factor intervention. Although these have been proven both safe and effective results from randomized clinical trials suggest that it is difficult to achieve relative risk reductions exceeding 40% with this approach. To further improve efficacy f...

journal_title：Journal of internal medicine

authors： Nilsson J,Fredrikson GN,Björkbacka H,Chyu KY,Shah PK

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:To determine whether a first myocardial infarction leads to increased plasma homocysteine concentrations and whether the association between homocysteine and myocardial infarction was greater at follow-up compared with baseline. DESIGN:A population-based, prospective, nested case-referent study. SETTING:Sc...

journal_title：Journal of internal medicine

authors： Hultdin J,Thøgersen AM,Jansson JH,Nilsson TK,Weinehall L,Hallmans G

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The aims of the study were (i) to examine which antithrombotic therapy patients with known atrial fibrillation use at the point of time when they suffer an ischaemic stroke, (ii) to evaluate the effects of optimal antithrombotic treatment on outcome and severity of the stroke. METHODS:Patients with known at...

journal_title：Journal of internal medicine

authors： Indredavik B,Rohweder G,Lydersen S

更新日期：2005-08-01 00:00:00

abstract：:The autoimmune rheumatological diseases rheumatoid arthritis (RA), spondyloarthritis (SpA) and systemic lupus erythematosus (SLE) are treated with conventional immunosuppressive agents and with modern biological immunomodulators. The latter group of medications have brought about a major change in our ability to contr...

journal_title：Journal of internal medicine

authors： van Vollenhoven RF

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Structural remodelling of left ventricle is a common feature in the progression of congestive heart failure (CHF). Matrix metalloproteinases (MMPs) have been directly implicated as they degrade extracellular proteins. To test the hypothesis that MMP-and its inhibitor, tissue type inhibitor of matrix metallop...

journal_title：Journal of internal medicine

authors： Jordán A,Roldán V,García M,Monmeneu J,de Burgos FG,Lip GY,Marín F

更新日期：2007-09-01 00:00:00

abstract：:A 40-year-old woman with previous parathyroidectomy for adenoma was found to have a serum calcium level of 5.35 mmol l-1 (21.4 mg dl-1). Inadvertent calcium overdose had occurred because of her mistaken belief that if some prescribed calcium was good, then more was better. Her misconception is in contrast with that of...

journal_title：Journal of internal medicine

authors： McAlister NH,Abrams HB,Schlosser R,Sturtridge W

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVES:Physical activity (PA) is a preventive strategy for cardiovascular disease and for managing cardiovascular risk factors. There is little information on the effectiveness of PA for the prevention of cardiovascular outcomes once cardiovascular disease is present. Thus, we studied the relationship between PA at...

journal_title：Journal of internal medicine

authors： Fossum E,Gleim GW,Kjeldsen SE,Kizer JR,Julius S,Devereux RB,Brady WE,Hille DA,Lyle PA,Dahlöf B

更新日期：2007-10-01 00:00:00

abstract：:Traumatic brain injury (TBI) is a major cause of acquired disability globally, and effective treatment methods are scarce. Lately, there has been increasing recognition of the devastating impact of TBI resulting from sports and other recreational activities, ranging from primarily sport-related concussions (SRC) but a...

journal_title：Journal of internal medicine

authors： Marklund N,Bellander BM,Godbolt AK,Levin H,McCrory P,Thelin EP

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVES:The angiotensinogen (AGT) gene has been implicated as a candidate gene of high blood pressure. However, because the variants of the AGT gene are point mutations, it is difficult to detect them in large scale population studies. The aims of this study were to develop a rapid screening method for the point mut...

journal_title：Journal of internal medicine

authors： Morise T,Takeuchi Y,Takeda R

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVES:Hypocitraturia is a risk factor for calcium nephrolithiasis. 1,25(OH)2D3 influences renal citrate handling and enhances citraturia. The aim of this study was to evaluate the relationship between vitamin D receptor (VDR) allelic variant and urinary citrate excretion in recurrent stone formers (SF) patients. ...

journal_title：Journal of internal medicine

authors： Mossetti G,Vuotto P,Rendina D,Numis FG,Viceconti R,Giordano F,Cioffi M,Scopacasa F,Nunziata V

更新日期：2003-02-01 00:00:00

abstract：:The link between inflammation and metabolism was apparent already early last century, but has recently been revitalized following molecular studies of atherosclerosis, obesity and insulin resistance. A growing list of nuclear receptors, pivotal players in lipid, xenobiotic and energy metabolism has been identified as ...

journal_title：Journal of internal medicine

authors： Arulampalam V

更新日期：2008-06-01 00:00:00

abstract：:There is clear heritability of human longevity. However, the genetics of ageing is likely to be complex. Evolution theory tells us not to expect genes that have been selected to promote ageing. Ageing is not programmed but results from accumulation of somatic damage, owing to limited investments in maintenance and rep...

journal_title：Journal of internal medicine

authors： Kirkwood TB

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Bradykinin-mediated angioedema (AE) is a complication associated with thrombolysis for acute ischemic stroke. Risk factors are unknown and management is discussed. OBJECTIVES:To clarify risk factors associated with bradykinin-mediated AE after thrombolysis for acute ischemic stroke. METHODS:In a case-contr...

journal_title：Journal of internal medicine

authors： Vigneron C,Lécluse A,Ronzière T,Bouillet L,Boccon-Gibod I,Gayet S,Doche E,Smadja D,Di Legge S,Dumont F,Gaudron M,Ion I,Marcel S,Sévin M,Vlaicu MB,Launay D,Arnaud I,Girard-Madoux P,Héroum C,Lefèvre S,Marc G,Obadi

更新日期：2019-12-01 00:00:00

abstract：:Twenty-six consecutive patients with primary biliary cirrhosis (PBC) from northern Sweden were studied regarding the occurrence and features of Sjögren's syndrome (SS). In more than 50% of the patients the rose bengal dye test showed conjunctival and/or corneal staining. In six patients keratoconjunctivitis sicca (KCS...

journal_title：Journal of internal medicine

authors： Uddenfeldt P,Danielsson A,Forssell A,Holm M,Ostberg Y

更新日期：1991-11-01 00:00:00

abstract：:The effects of resuscitation on patients who died suddenly out of hospital were evaluated after the introduction of early defibrillation performed by ambulance personnel using semi-automatic defibrillators. Resuscitation attempts were initiated in 548 patients during the 1-year study period. Mean ambulance delay was 7...

journal_title：Journal of internal medicine

authors： Jakobsson J,Rehnqvist N,Nyquist O

更新日期：1989-05-01 00:00:00

abstract：:This study was conducted to determine the relative importance of efferent muscle sympathetic nerve activity (MSA), vasopressin (ADH) and atrial natriuretic peptide (ANP) in the short-term neurohumoral response to moderate changes in low-pressure cardiopulmonary receptor activity. The low-pressure receptors were stimul...

journal_title：Journal of internal medicine

authors： Agewall S,Rhea B,Persson B,Karlberg B,Wallin G,Andersson OK

更新日期：1991-02-01 00:00:00