Pharmacokinetics and biodistribution of a small radioiodine labeled nerve growth factor fragment.

abstract：OBJECTIVE:In mCRPC patients treated with 223Ra, a major issue is the validation of reliable prognostic and predictive biomarkers to maximize clinical benefit and minimize toxicities and costs. Bearing in mind how changes in tALP did not meet statistical requirements as surrogate marker for survival, aim of this single-...

journal_title：Annals of nuclear medicine

authors： Frantellizzi V,Farcomeni A,Follacchio GA,Pacilio M,Pellegrini R,Pani R,De Vincentis G

更新日期：2018-02-01 00:00:00

abstract：:Evaluation of viral myocarditis is essential for the clinician to assess the prognosis. In this study, Tl-201 myocardial scintigraphy and Tc-99m gated cardiac blood pool scan were performed in 16 patients with myocarditis diagnosed by clinical symptoms and laboratory findings and these nuclear medicine techniques were...

journal_title：Annals of nuclear medicine

authors： Kawamura Y,Morishita T,Yamazaki J,Okuzumi I,Wakakura M,Muto T,Saji T,Matsuura H,Matsuo N,Yabe Y

更新日期：1990-07-01 00:00:00

abstract：AIM:The purpose of the study was to determine the lung toxicity caused by amiodarone (AD) and bleomycin (BLM) in rats, by means of Tc-99m HMPAO lung scintigraphy. METHODS:Thirty albino rats were randomly divided into five groups. After AD or BLM was dissolved with isotonic saline (SF), a 0.5 ml solution was applied to...

journal_title：Annals of nuclear medicine

authors： Gumuser G,Vural K,Varol T,Parlak Y,Tuglu I,Topal G,Sayit E

更新日期：2013-08-01 00:00:00

abstract：:67Ga-citrate and 99mTc(V)-DMSA images were obtained in a patient with recurrent extraabdominal fibromatosis of the left calf. The 67Ga-citrate image showed abnormal uptake in the left calf lesion and right calf, which was considered due to probable myositis caused by overexertion. On the other hand, the 99mTc(V)-DMSA ...

journal_title：Annals of nuclear medicine

authors： Ohta H,Komibuchi T,Tomihara M,Watanabe H,Fujikawa S,Shintaku M

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:Variable uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) has been noticed in positron emission tomography (PET) studies of gastric carcinoma patients, with low uptake occurring especially in some particular histological subtypes and early carcinomas. But this phenomenon has not been adequately explained. The ...

journal_title：Annals of nuclear medicine

authors： Yamada A,Oguchi K,Fukushima M,Imai Y,Kadoya M

更新日期：2006-11-01 00:00:00

abstract：:The increasing life expectancy in our society results in a continuously growing number of patients suffering from neurodegenerative disorders, particularly Alzheimer's disease (AD). Apart from the deleterious consequences for patients and their relatives, this issue has also alarming effects on our social systems. The...

journal_title：Annals of nuclear medicine

authors： Drzezga A

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:The aim of this study was to elucidate the regional differences between brain perfusion single photon emission computed tomography (SPECT) images reconstructed with a uniform attenuation correction using Chang's method (AC-Chang) and a non-uniform attenuation correction with CT using SPECT/CT (AC-CT). METHODS:...

journal_title：Annals of nuclear medicine

authors： Ishii K,Hanaoka K,Okada M,Kumano S,Komeya Y,Tsuchiya N,Hosono M,Murakami T

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:Praseodymium-142 [T 1/2 = 19.12 h, [Formula: see text] = 2.162 MeV (96.3%), Eγ = 1575 keV (3.7%)] is one of the (141)Pr radioisotopes. Many studies have been attempted to assess the significance of usage (142)Pr in radionuclide therapy. In many studies, the dosimetric parameters of (142)Pr sources were calcul...

journal_title：Annals of nuclear medicine

authors： Bakht MK,Jabal-Ameli H,Ahmadi SJ,Sadeghi M,Sadjadi S,Tenreiro C

更新日期：2012-06-01 00:00:00

abstract：:Identification and treatment of hibernating myocardium (HM) lead to improvement in LV function and prognosis in patients with post-ischemic heart failure. Different techniques are used to diagnose HM: echocardiography, MRI, SPECT and PET and, in patients with moderate LV impairment, their predictive values are similar...

journal_title：Annals of nuclear medicine

authors： Camici PG,Rimoldi OE

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:Attenuation correction (AC) on nuclear images of non-uniform domains is generally performed by a change of the computed tomography (CT) values to μ values, which are then inserted as components into the detection probability of iterative reconstruction techniques (OS-EM Iterative AC). We established an AC tec...

journal_title：Annals of nuclear medicine

authors： Nakamura Y,Tomiguchi S

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Lung clearance rates of inhaled (99m)Tc-DTPA aerosols constitute a sensitive index to evaluate the permeability changes characteristic of airway epithelial damage. It was thought that edema of the airway wall which is reported in asthma could be relieved with a diuretic like furosemide, helping to relieve the...

journal_title：Annals of nuclear medicine

authors： Bhure UN,Bhure SU,Bhatt BM,Mistry S,Pednekar SJ,Chari VV,Desai SA,Joshi JM,Paidhungat AJ

更新日期：2009-08-01 00:00:00

abstract：OBJECTS:The purpose was to evaluate the correlation of the pre-treatment hematological parameters with metabolic parameters of primary tumor in baseline 18F-FDG PET/CT in patients with colorectal cancer (CRC) and estimate the prognostic value of both. METHODS:We retrospectively investigated 231 patients with CRC who u...

journal_title：Annals of nuclear medicine

authors： Xu J,Li Y,Hu S,Lu L,Gao Z,Yuan H

更新日期：2019-01-01 00:00:00

abstract：:Cerebral perfusion single photon emission computed tomography (SPECT) has been used to confirm the localization of the epileptic focus and the evaluation of seizure. Recently, diffusion-weighted MR imaging (DWI) has been recognized for evaluation of seizure activity. We describe a case of transient seizure activity de...

journal_title：Annals of nuclear medicine

authors： Sagiuchi T,Ishii K,Asano Y,Aoki Y,Woodhams R,Yanaihara H,Kan S,Hayakawa K

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:We examined the diagnostic value of brain perfusion single-photon emission computed tomography (SPECT) using voxel-based statistical analysis with CT-based attenuation correction (CT-AC) by comparing it to that with Chang's AC in mild cognitive impairment (MCI) patients and attempted to locate brain areas tha...

journal_title：Annals of nuclear medicine

authors： Sohara K,Kiriyama T,Mizumura S,Ishiwata A,Yamazaki M,Kimura K,Kumita SI

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to elucidate the causes of false-negative cases of technetium-99 m methoxyisobutylisonitrile scintigraphy (MIBI) for hyperparathyroidism. METHODS:Consecutive MIBI examinations performed in 154 patients between April 2011 and March 2017 were retrospectively reviewed. Sensitivities of...

journal_title：Annals of nuclear medicine

authors： Ishii S,Sugawara S,Yaginuma Y,Kobiyama H,Hiruta M,Watanabe H,Yamakuni R,Hakozaki M,Fujimaki H,Ito H

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Aortic knob width on chest radiography represents the extent of aortic dialation and tortuosity of the aortic arch. We tested the hypothesis that aortic knob width reflected left ventricular (LV) diastolic function assessed by gated myocardial perfusion single photon emission computed tomography (SPECT) in p...

journal_title：Annals of nuclear medicine

authors： Kurisu S,Higaki T,Sumimoto Y,Ikenaga H,Watanabe N,Ishibashi K,Dohi Y,Fukuda Y,Kihara Y

更新日期：2017-04-01 00:00:00

abstract：PURPOSE:Treatment effect of radiofrequency ablation (RFA) is traditionally accomplished with MRI and/or CT. The aim of the study was to assess the role of FDG-PET in post RFA hepatic tumor evaluation, in comparison with MRI and CT. MATERIALS AND METHODS:28 patients (33 hepatic RFA lesions) who had post RFA FDG-PET wit...

journal_title：Annals of nuclear medicine

authors： Chen W,Zhuang H,Cheng G,Torigian DA,Alavi A

更新日期：2013-01-01 00:00:00

abstract：:Bacterial orbital cellulitis is an infection of the soft tissues behind the orbital septum. Cellulitis is seen as a poorly defined area of increased CT density or T2 signal intensity within the fat. There is an amorphous enhancement following contrast infusion. Radiolabeled leukocytes or granulocytes are now establish...

journal_title：Annals of nuclear medicine

authors： Sayit E,Söylev M,Capa G,Durak I,Ada E,Yilmaz M,Durak H

更新日期：2001-02-01 00:00:00

abstract：:The biodistribution and imaging characteristics of the 111In-labeled anti CEA monoclonal antibody ZCE-025 were studied in five patients with suspicion of colorectal carcinoma. Evaluation included antibody pharmacokinetics and assessment of antibody distribution in surgical specimen, making a comparison with whole-body...

journal_title：Annals of nuclear medicine

authors： Kubo A,Nakamura K,Katayama M,Hashimoto S,Teramoto T,Kodaira S

更新日期：1992-02-01 00:00:00

abstract：:A 62-year-old man with a soft, non-tender, movable mass 2.5 x 2.5-cm in diameter in the volar surface of the right index finger over the proximal phalanx underwent Tc-99m RBC perfusion and blood-pool scintigraphy to evaluate the vascular nature and extent of the mass. Highly increased activity on early and delayed blo...

journal_title：Annals of nuclear medicine

authors： Lim ST,Kim MW,Sohn MH

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:We performed 67Gallium (Ga) single-photon emission computed tomography (SPECT) with integrated low-dose computed tomography (CT) for the interpretation of myocardial outline to investigate the value of co-registered fusion imaging using a hybrid system (SPECT/CT) in patients with cardiac sarcoidosis. METHODS...

journal_title：Annals of nuclear medicine

authors： Momose M,Kadoya M,Koshikawa M,Matsushita T,Yamada A

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:We investigated the prevalence and clinical significance of incidental focal 18F-FDG uptake in the frontal process of the maxilla, mimicking malignancy on PET/CT. METHODS:From a total of 32,834 patients who underwent 18F-FDG PET/CT, patients with focal uptake in the frontal process of the maxilla were select...

journal_title：Annals of nuclear medicine

authors： Park SB,Choi JY,Kim HJ,Kim HJ,Lee KH,Kim BT

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:Vesicoureteral reflux (VUR) is a major risk factor for recurrent symptomatic urinary tract infection (UTI) in pediatric patients. In addition, dimercaptosuccinic acid renal scintigraphy (DMSA) is an important diagnostic modality of VUR. However, the value of DMSA for predicting recurrent pediatric UTI has not...

journal_title：Annals of nuclear medicine

authors： Kim D,Yoon HJ,Woo SH,Lee WJ,Kim BS,Chung YA,Oh JK

更新日期：2019-09-01 00:00:00

abstract：:We report a case of lung cancer arising from progressive massive fibrosis (PMF) associated with pneumoconiosis. In this case, fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) was able to clearly distinguish the lung cancer from PMF, suggesting a potential usefulness of FDG-PET in cancer screening ...

journal_title：Annals of nuclear medicine

authors： Bandoh S,Fujita J,Yamamoto Y,Nishiyama Y,Ueda Y,Tojo Y,Ishii T,Kubo A,Ishida T

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Because thickening of the gallbladder wall is observed not only in patients with gallbladder cancer but also in those with benign diseases such as chronic cholecystitis and gallbladder adenomyosis, it is difficult to distinguish between benign and malignant gallbladder wall thickening by conventional techniqu...

journal_title：Annals of nuclear medicine

authors： Oe A,Kawabe J,Torii K,Kawamura E,Higashiyama S,Kotani J,Hayashi T,Kurooka H,Tsumoto C,Kubo S,Shiomi S

更新日期：2006-12-01 00:00:00

abstract：:Whole-body positron emission tomography/computed tomography (PET/CT) with [(11)C]- and [(18)F]-labeled choline derivates has emerged as a promising molecular imaging modality for the evaluation of prostate cancer. (11)C- and (18)F-choline PET/CT are used successfully for restaging prostate cancer in patients with bioc...

journal_title：Annals of nuclear medicine

authors： Kitajima K,Murphy RC,Nathan MA

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:Epidermal growth factor receptor tyrosine kinase (EGFR-TK) represents an attractive target for tumor diagnosis agents. Previously, the radioiodinated 4-(3-iodoanilino)-6,7-diethoxyquinazoline ([(125)I]m-IPQ) has been reported to possess good characteristics as a tumor imaging agent; however, it was also found...

journal_title：Annals of nuclear medicine

authors： Hirata M,Kanai Y,Naka S,Matsumuro K,Kagawa S,Yoshimoto M,Ohmomo Y

更新日期：2012-06-01 00:00:00

abstract：:In order to quantitatively assess the extent and severity of myocardial ischemia by Tc-99m sestamibi exercise myocardial scintigraphy, we developed a new method of change rate (CR) mapping and examined its efficiency. CR was calculated to divide the counts per pixel in the stress polar map by that in the rest polar ma...

journal_title：Annals of nuclear medicine

authors： Nakata S,Higashino H,Kuwahara T,Tanada S,Hamamoto K

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the usefulness of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in differentiating pulmonary artery sarcoma from pulmonary embolism. MATERIALS AND METHODS:We evaluated three patients with pulmonary artery sarcoma and 10 patients with proximal pulmon...

journal_title：Annals of nuclear medicine

authors： Ito K,Kubota K,Morooka M,Shida Y,Hasuo K,Endo H,Matsuda H

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:Currently, neck ultrasound is the preferred preoperative imaging in patients with secondary/tertiary hyperparathyroidism, and the use of Tc-99m sestamibi scan is limited in these patients. We conducted this study to compare the diagnostic utilities of F-18 fluorocholine PET/CT, Tc-99m sestamibi scintigraphy,...

journal_title：Annals of nuclear medicine

authors： Chen YH,Chen HT,Lee MC,Liu SH,Wang LY,Lue KH,Chan SC

更新日期：2020-08-01 00:00:00