Amygdala activation at 3T in response to human and avatar facial expressions of emotions.

Abstract:

:Facial expressions of emotions are important in nonverbal communication. Although numerous neural structures have been identified to be involved in emotional face processing, the amygdala is thought to be a core moderator. While previous studies have relied on facial images of humans, the present study is concerned with the effect of computer-generated (avatar) emotional faces on amygdala activation. Moreover, elicited activation patterns in response to viewing avatar faces are compared with the neuronal responses to human facial expressions of emotions. Twelve healthy subjects (five females) performed facial emotion recognition tasks with optimized 3T event-related fMRI. Robust amygdala activation was apparent in response to both human and avatar emotional faces, but the response was significantly stronger to human faces in face-sensitive structures, i.e. fusiform gyri. We suggest that avatars could be a useful tool in neuroimaging studies of facial expression processing because they elicit amygdala activation similarly to human faces, yet have the advantage of being highly manipulable and fully controllable. However, the finding of differences between human and avatar faces in face-sensitive regions indicates the presence of mechanisms by which human brains can differentiate between them. This mechanism merits further investigation.

journal_name

J Neurosci Methods

authors

Moser E,Derntl B,Robinson S,Fink B,Gur RC,Grammer K

doi

10.1016/j.jneumeth.2006.10.016

subject

Has Abstract

pub_date

2007-03-30 00:00:00

pages

126-33

issue

1

eissn

0165-0270

issn

1872-678X

pii

S0165-0270(06)00508-5

journal_volume

161

pub_type

杂志文章
  • The image-combining computer microscope--an interactive instrument for morphometry of the nervous system.

    abstract::The image-combining computer microscope is a new configuration of light microscope and computer graphics instrumentation which provides remarkable morphometric capabilities over a wide range of applications. The key component is the well known camera lucida, an image-combining device that is used to superimpose the co...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(83)90048-1

    authors: Glaser EM,Tagamets M,McMullen NT,Van der Loos H

    更新日期:1983-05-01 00:00:00

  • High throughput quantification of mutant huntingtin aggregates.

    abstract::Mutant protein aggregates are an important biomarker in Huntington's and other neurodegenerative diseases however their quantification has typically relied on manual imaging and counting, or cell-free assays, which do not allow for concurrent analysis of cell viability. Here we describe four automated high throughput ...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2008.02.007

    authors: Scotter EL,Narayan P,Glass M,Dragunow M

    更新日期:2008-06-15 00:00:00

  • Randomising stimulus intensity improves the variability and reliability of the assessment of corticospinal excitability.

    abstract:BACKGROUND:Advances in the control of transcranial magnetic stimulation (TMS) have enabled greater randomisation of stimulus intensity. It is unclear if such randomisation improves assessments of corticospinal excitability. NEW METHOD:We recorded the amplitude of TMS-induced motor evoked potentials (MEPs) from the fir...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2020.108813

    authors: Suckley JJ,Waters TJ,Tran M,Stapley PJ,Shemmell J,Walsh JA,McAndrew DJ

    更新日期:2020-08-01 00:00:00

  • Modified herpes simplex virus delivery of enhanced GFP into the central nervous system.

    abstract::Controlled expression of proteins is a key experimental approach to a deeper understanding of the molecular basis of neuronal function. Here we evaluate the HSV-1 (herpes simplex virus) amplicon vector for gene delivery into the brains of living rats. We demonstrate that HSV-1 amplicon vectors expressing enhanced gree...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/s0165-0270(02)00262-5

    authors: Sandler VM,Wang S,Angelo K,Lo HG,Breakefield XO,Clapham DE

    更新日期:2002-12-15 00:00:00

  • Real-time spectral intensity analysis of the EEG on a common microcomputer.

    abstract::An inexpensive system for quantitative electroencephalogram (EEG) analysis over long time periods is described. This system continuously analyses EEG for intensity versus frequency content, and saves averaged 'data reduced' intensity spectra to disk at regular intervals. The method had adequate frequency resolution fo...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(90)90066-o

    authors: Williams CE,Gluckman PD

    更新日期:1990-04-01 00:00:00

  • Combined fluorescent in situ hybridization and immunofluorescence: limiting factors and a substitution strategy for slide-mounted tissue sections.

    abstract::The simultaneous localization of several anatomical markers is often required to understand and analyze the organization of complex brain nuclei or identify neuronal networks recruited during a specific biological stimulus. Gathering such information is usually achieved by the combined detection of both mRNA and prote...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2011.01.018

    authors: Nehmé B,Henry M,Mouginot D

    更新日期:2011-03-30 00:00:00

  • Quantitative analysis of cell columns in the cerebral cortex.

    abstract::We present a quantified imaging method that describes the cell column in mammalian cortex. The minicolumn is an ideal template with which to examine cortical organization because it is a basic unit of function, complete in itself, which interacts with adjacent and distance columns to form more complex levels of organi...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/s0165-0270(99)00192-2

    authors: Buxhoeveden DP,Switala AE,Roy E,Casanova MF

    更新日期:2000-04-01 00:00:00

  • The use of a muscle graft to repair a segmentary nerve defect. An experimental study using the sciatic nerve of rats as model.

    abstract::The use of a devitalized skeletal muscle graft and conventional nerve graft to repair a 5mm long segmentary sciatic nerve lesion was studied in rats by means of functional, morphometric and spinal cord motor neuron cell response evaluation. Thirty-four rats were used and divided into four groups according to the proce...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2003.09.010

    authors: Oliveira EF,Mazzer N,Barbieri CH,DelBel EA

    更新日期:2004-02-15 00:00:00

  • Influence of filters in the detrended fluctuation analysis of digital electroencephalographic data.

    abstract::The technique named detrended fluctuation analysis (DFA) has been used to reveal the presence of long-range temporal correlations (LRTC) and scaling behavior (SB) in electroencephalographic (EEG) recordings. The occurrence of these phenomena seems to be a salient characteristic of the healthy human brain and alteratio...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2008.01.010

    authors: Valencia M,Artieda J,Alegre M,Maza D

    更新日期:2008-05-30 00:00:00

  • Registration of in-vivo to ex-vivo MRI of surgically resected specimens: a pipeline for histology to in-vivo registration.

    abstract:BACKGROUND:Advances in MRI have the potential to improve surgical treatment of epilepsy through improved identification and delineation of lesions. However, validation is currently needed to investigate histopathological correlates of these new imaging techniques. The purpose of this work is to develop and evaluate a p...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2014.12.005

    authors: Goubran M,de Ribaupierre S,Hammond RR,Currie C,Burneo JG,Parrent AG,Peters TM,Khan AR

    更新日期:2015-02-15 00:00:00

  • Potential errors due to aliasing in digital video analysis of quantitative autoradiography.

    abstract::Digital image analysis of quantitative autoradiographic (QAR) films is widely used in neuroscience applications. Unless proper precautions are taken when autoradiographic images are converted to digital form they can be inadvertently modified by improper application of the sampling process. This type of modification i...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(91)90156-t

    authors: Lapin GD,Groothuis DR

    更新日期:1991-06-01 00:00:00

  • Application of triphasic pulses with adjustable phase amplitude ratio (PAR) for cochlear ECAP recording: II. recovery functions.

    abstract::Triphasic electrical stimulation pulses with an adjustable phase amplitude ratio (PAR) can reduce stimulus artifacts in electrically evoked compound actions potentials (ECAPs) recording in the cochlea (see companion paper Bahmer and Baumann, submitted for publication). The present study describes the application of tr...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2011.12.006

    authors: Bahmer A,Baumann U

    更新日期:2012-03-30 00:00:00

  • Dependence of the paired motor unit analysis on motor unit discharge characteristics in the human tibialis anterior muscle.

    abstract::The paired motor unit analysis provides in vivo estimates of the magnitude of persistent inward currents (PIC) in human motoneurons by quantifying changes in the firing rate (ΔF) of an earlier recruited (reference) motor unit at the time of recruitment and derecruitment of a later recruited (test) motor unit. This stu...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2011.03.018

    authors: Stephenson JL,Maluf KS

    更新日期:2011-05-15 00:00:00

  • A new informed tensor factorization approach to EEG-fMRI fusion.

    abstract:BACKGROUND:In this paper exploitation of correlation between post-movement beta rebound in EEG and blood oxygenation level dependent (BOLD) in fMRI is addressed. Brain studies do not reveal any clear relationship between synchronous neuronal activity and BOLD signal. Simultaneous recording of EEG and fMRI provides a gr...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2015.07.018

    authors: Ferdowsi S,Abolghasemi V,Sanei S

    更新日期:2015-10-30 00:00:00

  • Computer-driven automatic identification of locomotion states in Caenorhabditis elegans.

    abstract::We developed a computer-driven tracking system for the automated analysis of the locomotion of Caenorhabditis elegans. The algorithm for the identification of locomotion states on agar plates (forward movement, backward movement, rest, and curl) includes the identification of the worm's head and tail. The head and tai...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2006.05.002

    authors: Hoshi K,Shingai R

    更新日期:2006-10-30 00:00:00

  • A method for investigating cortical control of stand and squat in conscious behavioral monkeys.

    abstract::Technical challenges to record cortical unit spikes in conscious behavior monkeys have been presenting constraints in the investigation of cortical control of lower limb. Here we report a novel experimental system for investigation of correlation between cortical neuronal signals and standing and squatting movement. T...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2010.06.027

    authors: Ma C,He J

    更新日期:2010-09-30 00:00:00

  • Horseradish peroxidase histochemistry on mounted sections from embedded specimen: a simple method for serial reconstruction of neuronal projections.

    abstract::A combination of two procedures, embedding of specimens and horseradish peroxidase (HRP) histochemistry on mounted serial sections, is proposed for three-dimensional reconstruction of neuronal projections. To clarify the intrinsic organization of the peripheral nervous system, this simple method is more adequate than ...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(86)90130-5

    authors: Streinzer W,Krammer EB

    更新日期:1986-09-01 00:00:00

  • Trial-to-trial noise cancellation of cortical field potentials in awake macaques by autoregression model with exogenous input (ARX).

    abstract::Gamma band synchronization has drawn increasing interest with respect to its potential role in neuronal encoding strategy and behavior in awake, behaving animals. However, contamination of these recordings by power line noise can confound the analysis and interpretation of cortical local field potential (LFP). Existin...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2010.10.029

    authors: Wang Z,Roe AW

    更新日期:2011-01-15 00:00:00

  • Clearing techniques for visualizing the nervous system in development, injury, and disease.

    abstract::Modern clearing techniques enable high resolution visualization and 3D reconstruction of cell populations and their structural details throughout large biological samples, including intact organs and even entire organisms. In the past decade, these methods have become more tractable and are now being utilized to provi...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章,评审

    doi:10.1016/j.jneumeth.2020.108594

    authors: Porter DDL,Morton PD

    更新日期:2020-01-13 00:00:00

  • Electron microscopic imaging of multiple markers in glutaraldehyde fixed CNS tissue of Macaca fascicularis: maximizing information from a single experimental animal.

    abstract::Sensory and motor pathways in the central nervous system (CNS) of macaque monkeys were visualized by anterograde or retrograde axonal transport of wheatgerm agglutinin-horseradish peroxidase (WGA-HRP) reacted with the chromagen tetramethylbenzidine (TMB), or by the use of anterograde degeneration after specific ablati...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(94)00117-y

    authors: Milroy AM,Ralston DD

    更新日期:1995-02-01 00:00:00

  • A semi-in-vivo preparation for optical recording of the insect brain.

    abstract::We describe a method for optically recording neuronal activity from an intact insect brain, upon natural sensory stimulation. In this preparation, the head capsule of the honeybee, Apis mellifera, is isolated from the body while leaving the entire brain undamaged. In short, a hole is first cut into the cuticule to all...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/s0165-0270(97)00080-0

    authors: Galizia CG,Joerges J,Küttner A,Faber T,Menzel R

    更新日期:1997-09-05 00:00:00

  • Oxygen-enriched photoconversion of fluorescent dyes by means of a closed conversion chamber.

    abstract::The goal of the present study was an improvement of the widely used photoconversion technique, which still represents the major approach to the ultrastructural analysis of tissue labelled with fluorescent dyes. Since free access of oxygen to the tissue is essential for the dye-dependent photooxidation of diaminobenzid...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/s0165-0270(96)00150-1

    authors: Kacza J,Härtig W,Seeger J

    更新日期:1997-02-01 00:00:00

  • Multi-lipofection efficiently transfected genes into astrocytes in primary culture.

    abstract::This study demonstrated that liposome-mediated transfection - lipofection - is suitable for delivering genes into astrocytes. By repeatedly lipofecting the same astrocyte cultures, a process we call multi-lipofection, the transfection efficiency of the beta-galactosidase (beta-gal) gene was improved from 2.6+/-0.6 to ...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/s0165-0270(00)00285-5

    authors: Wu BY,Liu RY,So KL,Yu AC

    更新日期:2000-10-30 00:00:00

  • Reversed-phase liquid chromatographic purification and isolation of a radio-iodinated selective probe for mu opioid receptors in the brain.

    abstract::A Guard-PAK precolumn system was used for the reversed-phase liquid chromatography purification of a small, synthetic radiolabeled opioid peptide, FK 33-824 (D-Ala2, methyl-phe4, Met (O)ol5 enkephalin) (FK). This procedure involves trace enrichment of iodinated peptide onto the precolumn while iodination reagents are ...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(92)90052-f

    authors: Miller MM,Gould BE,Joshi D,Bennett HP,James S,Billiar RB

    更新日期:1992-02-01 00:00:00

  • Stimulation of Ca²+ signals in neurons by electrically coupled electrolyte-oxide-semiconductor capacitors.

    abstract::Electrolyte-oxide-semiconductor capacitors (EOSCs) are a class of microtransducers for extracellular electrical stimulation that have been successfully employed to activate voltage-dependent sodium channels at the neuronal soma to generate action potentials in vitro. In the present work, we report on their use to cont...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2011.02.009

    authors: Giacomello M,Girardi S,Scorzeto M,Peruffo A,Maschietto M,Cozzi B,Vassanelli S

    更新日期:2011-05-15 00:00:00

  • In situ three-dimensional reconstruction of mouse heart sympathetic innervation by two-photon excitation fluorescence imaging.

    abstract:BACKGROUND:Sympathetic nerve wiring in the mammalian heart has remained largely unexplored. Resolving the wiring diagram of the cardiac sympathetic network would help establish the structural underpinnings of neurocardiac coupling. NEW METHOD:We used two-photon excitation fluorescence microscopy, combined with a compu...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2013.09.005

    authors: Freeman K,Tao W,Sun H,Soonpaa MH,Rubart M

    更新日期:2014-01-15 00:00:00

  • Topology-Guided Cyclic Brain Connectivity Generation using Geometric Deep Learning.

    abstract:BACKGROUND:There is a growing need for analyzing medical data such as brain connectomes. However, the unavailability of large-scale training samples increases risks of model over-fitting. Recently, deep learning (DL) architectures quickly gained momentum in synthesizing medical data. However, such frameworks are primar...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2020.108988

    authors: Sserwadda A,Rekik I

    更新日期:2020-11-04 00:00:00

  • Rapid quantification of ischaemic injury and cerebroprotection in brain slices using densitometric assessment of 2,3,5-triphenyltetrazolium chloride staining.

    abstract::2,3,5-Triphenyltetrazolium chloride (TTC), a marker of mitochondrial enzyme activity, is widely used to assess the effects of cerebral ischaemia in vivo. In the present study, we characterised its utility as a simple rapid macrohistological measure of ischaemic damage in brain slices. Coronal rat corticostriatal slice...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/s0165-0270(00)00277-6

    authors: Mathews KS,McLaughlin DP,Ziabari LH,Toner CC,Street PC,Hisgrove E,Bezzina EL,Stamford JA

    更新日期:2000-10-15 00:00:00

  • A concentration-clamp system allowing two-electrode voltage-clamp investigations in oocytes of Xenopus laevis.

    abstract::A system for rapid solution exchange (concentration-clamp) was developed for Xenopus laevis oocytes. The exchange time (t90) was 10 ms. The system allows two-electrode voltage-clamp investigations. ...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(91)90178-3

    authors: Madeja M,Musshoff U,Speckmann EJ

    更新日期:1991-07-01 00:00:00

  • A flow rate monitor for a variety of physiological preparations, including in vitro brain slices.

    abstract::A flow rate monitor system for constant perfusion of media for maintaining physiological preparations, particularly in vitro brain slices, is described. The system consists of 3 components: the counter with a drip rate meter and alarm; a drop sensor; and a remote DC power supply. It provides accurate and immediate rea...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(88)90024-6

    authors: Rinaldi PC,Brown AM

    更新日期:1988-02-01 00:00:00