Abstract:
:The objective of the study was to determine the relationship between cadmium (Cd) intake and cadmium toxicity indicators by meta-analysis of literature data, in particular beta2-microglobulin (beta2MC), and to compare the results with the current Provisional Tolerable Weekly Intake (PTWI) set by FAO/WHO. The literature survey identified 79 feeding trials involving 27,537 people that were suitable for extraction of cadmium intake, levels in blood and urine and beta2-microglobulin in urine. There was an exponential increase in beta2-microglobulin with increases in cadmium intake above 302 micro g/day, which corresponds to a PTWI of 3.02 micro g/kg of body weight, when a safety margin of 10 is included. This compares with the current level set by FAO/WHO of 7 micro g/kg of body weight. Cadmium in blood and urine were also positively related to cadmium intake and participants' age. There were two principal components of variation in the data set, first: cadmium intake, concentrations of cadmium in blood, urine and beta2-microglobulin in urine, and second: duration and age of exposure.
journal_name
Environ Resjournal_title
Environmental researchauthors
Omarova A,Phillips CJdoi
10.1016/j.envres.2006.09.006subject
Has Abstractpub_date
2007-03-01 00:00:00pages
432-40issue
3eissn
0013-9351issn
1096-0953pii
S0013-9351(06)00199-Xjournal_volume
103pub_type
杂志文章,meta分析,评审abstract::The effects of methylmercury administration on adenosine 3',5'-cyclic monophosphate (cAMP)-dependent protein kinase (protein kinase A) and protein kinase C were investigated by determining their second messenger bindings ([3H]cAMP binding for protein kinase A and [3H]PDBu for protein kinase C) and enzymatic activities...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1993.1146
更新日期:1993-11-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108846
更新日期:2020-02-01 00:00:00
abstract::Exposure to environmental noise has been associated with hypertension, but the related mechanism of vascular structural changes is unclear. This repeated-measure study investigated the effects of noise exposure on the 24-h ambulatory vascular structural properties in 66 adults aged 18-32 years. Individual noise exposu...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2012.06.008
更新日期:2012-10-01 00:00:00
abstract::Formaldehyde poses significant threats to the ecosystem and is widely used as a toxicity indicator to obtain electrical signal feedback in electroactive biofilm (EAB)-based sensors. Although many optimizations have been adopted to improve the performance of EAB to formaldehyde, nearly no studies have discussed the tox...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109143
更新日期:2020-04-01 00:00:00
abstract::Several epidemiological studies have shown that the farm environment impacts allergy protection mechanisms in children. These associations are not well understood, but it is thought that contact to microorganisms may mediate this effect. For example, heat-inactivated Listeria (L.) monocytogenes have been successfully ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2008.02.007
更新日期:2008-07-01 00:00:00
abstract::Household solid fuel use is a major source of many air pollutants causing severe air pollution and adverse health outcomes. In evaluation of health impacts of household air pollution, it is essential to characterize toxic properties like mutagenicity of residential fuel combustion emissions and exposure assessments. M...
journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1016/j.envres.2017.05.001
更新日期:2017-07-01 00:00:00
abstract::Soil heavy metal pollution assessment is an important procedure in soil quality and ecological risk management, for which different mathematical models have been developed. However, these models have often failed to consider the characteristics of both heavy metals and the polluted sites. In this study, we analyzed th...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110246
更新日期:2021-01-01 00:00:00
abstract::Natural-occurring minerals representative of six silicate classes were examined for their influence on interferon induction by influenza virus in Rhesus monkey kidney (LLC-MK2) cell monolayers. Minerals within the classes nesosilicate, sorosilicate, cyclosilicate, and inosilicate exhibited either little or marked (50%...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(87)80040-3
更新日期:1987-08-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2009.04.009
更新日期:2009-08-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(05)80106-9
更新日期:1991-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.12.026
更新日期:2015-02-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(87)80206-2
更新日期:1987-04-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1997.3764
更新日期:1997-11-01 00:00:00
abstract::Vehicle traffic is responsible for a significant portion of toxic air pollution in urban areas that has been linked to a wide range of adverse health outcomes. Most vehicle air quality analyses used for transportation planning and health effect studies estimate exposure from the measured or modeled concentration of an...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108999
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:It remains unclear as to whether neglecting residential mobility during pregnancy introduces bias in studies investigating air pollution and adverse perinatal outcomes, as most studies assess exposure based on residence at birth. The aim of this study was to ascertain whether such bias can be observed in a s...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.02.001
更新日期:2016-05-01 00:00:00
abstract::Soil contaminants are common in industrialized countries, causing widespread contamination directly of soil and indirectly of ground water and food. Among these pollutants particular attention should be paid to soil mutagens and carcinogens due to their potentially hazardous effects on animal populations and human hea...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.2001.4317
更新日期:2002-01-01 00:00:00
abstract::Although industrialized nations have restricted or banned many organochlorine pesticides, some of these chemicals (e.g., endosulfans) are still used, on the assumption that they pose little threat to the environment, wildlife, or human health. According to available information, Spain is the main consumer of endosulfa...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2004.08.008
更新日期:2005-06-01 00:00:00
abstract::This study characterized nitrate-nitrogen (NO3-N) concentrations in groundwater and stream water in an agricultural head watershed in South Korea and identified the pollution load of NO3-N as a result of the groundwater entering streams using field surveys, analyses of chemical constituents, and numerical modeling. Th...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109313
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:It is unknown if higher levels of ambient particulate matter (PM) exposure increase the risk for premature ventricular contractions (PVC) in a population-based study of men and women, and if this relationship varies by race or sex. METHODS:We examined the association of PM <2.5µm in diameter (PM2.5) concent...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.12.031
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Hexavalent chromium (Cr(6+)) has long been recognized as an inhalation carcinogen. Useful data on its carcinogenicity by ingestion have been slower to develop. The 2008 NTP chronic bioassay of sodium dichromate dihydrate in drinking water found clear evidence of carcinogenicity in rodents and allows a genera...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2010.08.002
更新日期:2010-11-01 00:00:00
abstract::The acute toxicity of azodrin (monocrotophos, an organophosphorus insecticide) was determined on a soil organism, Eisenia foetida. The median lethal concentrations (LC50) were derived from a 48-h paper contact test and from artificial soil tests. The LC50 of azodrin in the paper contact test was 0.46 +/- 0.1 microg cm...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2004.02.014
更新日期:2004-11-01 00:00:00
abstract::We conducted a cross-sectional study in Sweden, Italy and Poland to assess environmental and occupational exposure to mercury from chloralkali (CA) plants and the potential association with biomarkers of early renal dysfunction. Questionnaire data and first-morning urine samples were collected from 757 eligible subjec...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2008.06.005
更新日期:2008-10-01 00:00:00
abstract::Since deforestation has recently been associated with increased mercury load in the Amazon, the problem of mercury exposure is now much more widespread than initially thought. A previous exploratory study suggested that fruit consumption may reduce mercury exposure. The objectives of the study were to determine the ef...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2007.01.012
更新日期:2007-10-01 00:00:00
abstract::Urban renewal efforts are a priority for many American cities. As efforts to reconstitute urban centers increase, the demolition of old, deteriorated structures has accelerated. Recent studies have identified demolitions as a potential source of environmental lead exposure. We conducted a study examining the relations...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2006.09.011
更新日期:2007-03-01 00:00:00
abstract::The influence of anthropogenic pollution, particularly with polycyclic aromatic hydrocarbons (PAHs) on soil toxicity and spread of antibiotic resistance genes (ARGs) is extremely important nowadays. We studied 20 soil samples from a technogenically polluted site, municipal solid wastes (MSW) landfills, and rural settl...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2021.110715
更新日期:2021-01-11 00:00:00
abstract::The effects of polycyclic aromatic hydrocarbons (PAHs) on microsomal liver enzymes were examined in rainbow trout. Various PAHs (naphthalene through benzo(a)pyrene [B(a)P]) were injected ip to screen for mixed-function oxidase (MFO) activity. Chrysene, B(a)P, and Aroclor 1254 caused MFO induction. When fish were also ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(78)90031-2
更新日期:1978-10-01 00:00:00
abstract:BACKGROUND:Drinking water (DW) is an important dietary source of magnesium. Recently, Israel has increased its use of desalinated seawater (DSW) as DW country-wide. Its negligible magnesium content, however, raises concern that consumption of DSW may be associated with hypomagnesemia and increase the risk of ischemic h...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.06.053
更新日期:2018-10-01 00:00:00
abstract::Adult male inbred Wistar rats were given a subtoxic dose of cadmium (25 ppm) orally for 4 weeks prior to and during immunization with sheep erythrocytes (E). The control group received tap water during the experimental period. No difference in the antibody response to E was found between the two groups. Mononuclear pe...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(83)90019-1
更新日期:1983-08-01 00:00:00
abstract::A special version of the NOAA HYSPLIT_4 model has been developed and used to estimate the atmospheric fate and transport of mercury in a North American modeling domain. Spatial and chemical interpolation procedures were used to expand the modeling results and provide estimates of the contribution of each source in a 1...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2003.11.007
更新日期:2004-07-01 00:00:00
abstract::Airborne particles, including both ultrafine and supermicrometric particles, contain various carcinogens. Exposure and risk-assessment studies regularly use particle mass concentration as dosimetry parameter, therefore neglecting the potential impact of ultrafine particles due to their negligible mass compared to supe...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.07.019
更新日期:2015-10-01 00:00:00