Abstract：
:The effect of cadmium on thyroxine (T4) outer ring monodeiodination was studied in vivo and in vitro in the rat liver. One microgram of T4 was incubated with rat liver homogenates in 50 mM Tris--HCl buffer, pH 7.4, with or without 0.5, 5, and 50 mM dithiothreitol (DTT) for 60 min in the presence of 10(-8) to 10(-3) M CdCl2, and the amount of 3,5,3'-triiodothyronine (T3) produced was determined by a specific radioimmunoassay. Subcutaneous injection of CdCl2, 1 mg/kg BW/day, 5 days a week for 10 weeks, to the rats resulted in a significant reduction in serum T3 concentration (by 37%) and hepatic T3 production from T4 (by 78 to 92%). In vitro addition of 1 microM to 1 mM CdCl2 to liver homogenates caused a concentration-dependent reduction in T3 generation. Without DTT a 50% reduction in the T4 to T3 converting activity was caused by 4 X 10(-6) M CdCl2. DTT (0.5 to 50 mM) partially restored T3 generation roughly in a concentration-dependent manner. These results indicate that cadmium has some effects on the metabolism of thyroid hormone.
journal_name
Environ Resjournal_title
Environmental researchauthors
Yoshida K,Sugihira N,Suzuki M,Sakurada T,Saito S,Yoshinaga K,Saito Hdoi
10.1016/s0013-9351(87)80206-2subject
Has Abstractpub_date
1987-04-01 00:00:00pages
400-5issue
2eissn
0013-9351issn
1096-0953pii
S0013-9351(87)80206-2journal_volume
42pub_type
杂志文章abstract：:Air pollution caused by particulate matter (PM) has become a serious issue, and significant research has focused on managing large stationary emission sources, i.e., the primary sources of PM. Currently, the U.S. Environmental Protection Agency (EPA) Method 201A and ISO 23210 are predominantly employed to measure the ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110507
更新日期：2021-02-01 00:00:00
abstract：:Blood samples and questionnaire background data were collected from 96 children (age 2-14 years) living in urban, suburban, or rural areas with varying traffic intensity and industrial lead pollution in Uruguay. Spot samples of tap water were collected from the homes of 44 children, and samples of top soil were taken ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1997.3742
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:There is mixed evidence implicating prenatal exposure to particulate matter <2.5 μm in aerodynamic diameter (PM2.5) in the risk of gestational diabetes mellitus (GDM) and only one study has examined exposure to PM2.5 constituents, which vary with location because of different emission sources. METHODS:We co...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109988
更新日期：2020-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110358
更新日期：2020-10-24 00:00:00
abstract：BACKGROUND:Adverse cardiovascular events have been linked with PM2.5 exposure obtained primarily from air quality monitors, which rarely co-locate with participant residences. Modeled PM2.5 predictions at finer resolution may more accurately predict residential exposure; however few studies have compared results across...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.07.041
更新日期：2017-11-01 00:00:00
abstract：:The purpose of these laboratory tests was to assess the impact of 50 Hz EMF (electromagnetic field) on the disappearance of azoxystrobin (active ingredient (AI) of Amistar 250 SC) and λ-cyhalothrin (AI of Karate Zeon 050 CS) in the body of honey bees (Apis mellifera) and the structure of some functional groups of the ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109989
更新日期：2020-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2009.09.008
更新日期：2010-01-01 00:00:00
abstract：:The Kastanozem complex in the dry steppe of southern Russia underlies an artificially-constructed forest strips. Deep ploughing to a depth of 45 cm was used to process the soil prior to planting. Between 20 and 40 cm depth, soil density was high, 1.57 t m-3. Soil hardness was also high, 440 psi. Soil aggregates greate...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110605
更新日期：2020-12-13 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2006.05.004
更新日期：2007-02-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2006.09.011
更新日期：2007-03-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.04.030
更新日期：2016-07-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.06.041
更新日期：2016-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.07.023
更新日期：2017-10-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2005.02.007
更新日期：2005-06-01 00:00:00
abstract：:Despite the behaviors of ZnO nanoparticles (ZnO NPs) in wastewater treatment processes have been widely explored, the impacts of ZnO NPs on the activated sludge's flocculation and sedimentation performances for solid-liquid separation have rarely been involved yet. In this study, ZnO NPs were observed to exert a dose-...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110256
更新日期：2021-01-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.01.024
更新日期：2019-04-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.10.002
更新日期：2017-01-01 00:00:00
abstract：:Recently, the World Health Organization Study Group on Tobacco Product Regulation (WHO TobReg) announced a priority list of 38 toxicants among the more than 7000 chemicals found in cigarette smoke, building upon previous lists of toxicants in cigarette smoke. Here, we conducted a comprehensive study on the quantitativ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.11.012
更新日期：2019-02-01 00:00:00
abstract：:Bisphenol A (BPA) and its main substitute, bisphenol S (BPS), are synthetic organic compounds found in various consumer products, in particular food and beverage containers. Numerous reports have shown a link between bisphenol exposure, human contamination and increased health problems. BPA, BPS and their metabolites ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110336
更新日期：2020-10-20 00:00:00
abstract：:Accidental contamination of livestock in Michigan in 1973 with polybrominated biphenyls (PBBs) led to the establishment of a registry of exposed individuals in 1976. At the time of enrollment, serum was collected and analyzed for PBBs and polychlorinated biphenyls (PCBs). In 1997, women aged 18 years or older and acti...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2006.11.010
更新日期：2007-10-01 00:00:00
abstract：:Source apportionment in biological or environmental samples using the lead isotope method, where there are diverse sources of lead, relies on a significant difference between the isotopic composition in the target media and the sources. Because of the unique isotopic composition of Australian lead, source apportionmen...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2005.03.006
更新日期：2006-01-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108602
更新日期：2019-10-01 00:00:00
abstract：:Cigarette smoke and hydrocortisone acetate (HCA) induce marked abnormalities in lungs of C57BL/6J male mice. In many pulmonary regions of smoke-exposed, HCA-treated animals, alveoli were highly congested with surfactant and flocculent material. In addition, prominent alveolar collapse and septal hypertrophy were commo...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(83)90074-9
更新日期：1983-06-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109701
更新日期：2020-09-01 00:00:00
abstract：:We attempted to develop a brief test battery to assess mental state for use in occupational health care settings. As a first step, we focused on the following three psychosocial aspects: ego state, behavioral pattern, and mood state which were considered to be closely related to mental state. To evaluate these paramet...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1993.1073
更新日期：1993-05-01 00:00:00
abstract：OBJECTIVE:Phthalates are non-persistent pollutants related to impaired metabolism and high cardiovascular risk. Their toxic metabolites are eliminated through urine and feces. Prevention policies are considered by the governments, although no therapeutic strategy to facilitate their elimination from the human body has ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110316
更新日期：2021-01-01 00:00:00
abstract：:Wood dust is one of the most common occupational exposures, with about 3.6 million of workers in the wood industry in Europe. Wood particles can deposit in the nose and the respiratory tract and cause adverse health effects. Occupational exposure to wood dust has been associated with malignant tumors of the nasal cavi...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.03.058
更新日期：2019-06-01 00:00:00
abstract：:Polychlorinated biphenyls (PCBs) and polychlorinated dibenzofurans (PCDFs) are ubiquitous pollutants found in the environment and human tissues. A cohort in Taiwan has undergone follow-up for 24 years after exposure to high levels of PCBs and PCDFs. The incidence of chloracne, hyperkeratosis, and abnormal nail was inc...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2008.07.006
更新日期：2008-10-01 00:00:00
abstract：:Mild gasification of coal is a technology being developed in the United States in order to upgrade lower rank coals and facilitate their use in coal-burning electric generation plants. Thirteen coal-derived mild gasification products from different coal sources and processing conditions have been examined for their po...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1996.3676
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:Immigrant women are often identified as being particularly vulnerable to environmental exposures and health effects. The availability of biomonitoring data on newcomers is limited, thus, presenting a challenge to public health practitioners in the identification of priorities for intervention. OBJECTIVES:In...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.12.013
更新日期：2017-04-01 00:00:00
