Abstract：
PURPOSE:To report one-year results of the Tube Versus Trabeculectomy (TVT) Study. DESIGN:Multicenter randomized clinical trial. METHODS: SETTING:17 Clinical Centers. STUDY POPULATION:Patients 18 to 85 years of age who had previous trabeculectomy and/or cataract extraction with intraocular lens implantation and uncontrolled glaucoma with intraocular pressure (IOP) > or =18 mm Hg and < or =40 mm Hg on maximum tolerated medical therapy. INTERVENTIONS:350 mm(2) Baerveldt glaucoma implant or trabeculectomy with mitomycin C (MMC). MAIN OUTCOME MEASURES:IOP, visual acuity, and reoperation for glaucoma. RESULTS:A total of 212 eyes of 212 patients were enrolled, including 107 in the tube group and 105 in the trabeculectomy group. At one year, IOP (mean +/- SD) was 12.4 +/- 3.9 mm Hg in the tube group and 12.7 +/- 5.8 mm Hg in the trabeculectomy group (P = .73). The number of glaucoma medications (mean +/- SD) was 1.3 +/- 1.3 in the tube group and 0.5 +/- 0.9 in the trabeculectomy group (P < .001). The cumulative probability of failure during the first year of follow-up was 3.9% in the tube group and 13.5% in the trabeculectomy group (P = .017). CONCLUSIONS:Nonvalved tube shunt surgery was more likely to maintain IOP control and avoid persistent hypotony or reoperation for glaucoma than trabeculectomy with MMC during the first year of follow-up in the TVT Study. Both surgical procedures produced similar IOP reduction at one year, but there was less need for supplemental medical therapy following trabeculectomy with MMC.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Gedde SJ,Schiffman JC,Feuer WJ,Herndon LW,Brandt JD,Budenz DLdoi
10.1016/j.ajo.2006.07.020subject
Has Abstractpub_date
2007-01-01 00:00:00pages
9-22issue
1eissn
0002-9394issn
1879-1891pii
S0002-9394(06)00860-9journal_volume
143pub_type
杂志文章,多中心研究,随机对照试验abstract：:In two patients, a 55-year-old man and a 49-year-old man, who had fungal keratitis initially undiagnosed by corneal scrapings the condition was successfully diagnosed by corneal biopsy. We compared corneal biopsy specimens and corneal scraping in the diagnosis of keratomycosis in rabbits with experimental bilateral fu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90821-4
更新日期：1986-03-15 00:00:00
abstract：:Ophthalmomyiasis interna caused severe intraocular inflammation and loss of vision in two eyes. In the first eye, the organism was found in the vitreous and created a severe uveitis; a second-stage larva of Hypoderma lineatum was later removed from the anterior chamber. Phthisis bulbi ensued with loss of all vision. I...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90381-7
更新日期：1984-05-01 00:00:00
abstract：PURPOSE:To assess the effect of verteporfin photodynamic therapy (PDT) in juxtafoveal choroidal neovascularization (CNV) secondary to pathologic myopia (PM). DESIGN:Prospective, open-label, consecutive, interventional case series. METHODS:We prospectively followed a series of 48 consecutive patients (49 eyes) with pa...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.11.037
更新日期：2007-03-01 00:00:00
abstract：PURPOSE:To report a case of nodular scleritis and panuveitis associated with erythema elevatum diutinum, a rare immunocomplex-mediated skin disease. DESIGN:Observational case report. METHODS:A 22-year-old woman who was diagnosed with erythema elevatum diutinum developed nodular scleritis and panuveitis of the right e...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/S0002-9394(03)00907-3
更新日期：2004-02-01 00:00:00
abstract：PURPOSE:To report on the presence of retinal pigment epithelium (RPE) humps in high myopia, and to describe the distinctive features from pathologic RPE detachments and choroidal neovascularizations (CNVs). DESIGN:Retrospective cross-sectional study. METHODS:Charts and imaging studies of highly myopic patients presen...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.07.013
更新日期：2017-10-01 00:00:00
abstract：PURPOSE:To review the contributions to ophthalmic genetics through the American Journal of Ophthalmology (AJO). DESIGN:Perspective. METHODS:A literature search to retrieve original articles, letters, editorials, and published lectures from 1966 to 2017, providing a 50-year review. Titles were excluded that gave no re...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.ajo.2018.03.004
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To investigate the value of whole-body positron emission tomography/computed tomography (PET/CT) as a screening tool for patients with uveal metastasis. DESIGN:Retrospective observational case series. METHODS:setting: Clinical practice. study population: Eighteen patients with uveal metastatic tumors were eva...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.09.028
更新日期：2012-04-01 00:00:00
abstract：PURPOSE:To determine whether the hepatocyte growth factor is increased in the vitreous of patients with proliferative vitreoretinopathy. METHODS:We assayed hepatocyte growth factor levels by enzyme-linked immunosorbent assay (ELISA) in vitreous samples from 65 consecutive eyes (65 patients) with proliferative vitreore...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00360-3
更新日期：2000-05-01 00:00:00
abstract：PURPOSE:To determine whether clinically isolated anterior segment recurrence is associated with concomitant subclinical choroidal inflammation in Vogt-Koyanagi-Harada (VKH) disease. DESIGN:Interventional, retrospective case series. METHODS:Nine patients with recurrent VKH disease who satisfied the following criteria:...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.10.012
更新日期：2008-03-01 00:00:00
abstract：PURPOSE:To describe a case of infantile neuroaxonal dystrophy with optic nerve atrophy and to discuss the diagnostic role of conjunctival biopsy. METHODS:We performed a complete ophthalmologic examination and a diagnostic conjunctival biopsy on a girl with a neurodegenerative disease. RESULTS:On the basis of "spheroi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71051-7
更新日期：1997-02-01 00:00:00
abstract：PURPOSE:To evaluate the ocular biometric parameters associated with intraocular pressure (IOP) reduction after phacoemulsification. DESIGN:Prospective, observational case series. METHODS:The study included 999 patients who had undergone uncomplicated phacoemulsification. IOP and ocular biometric parameters were check...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.02.003
更新日期：2013-07-01 00:00:00
abstract：PURPOSE:To examine surgical and refractive outcomes of phacoemulsification with intraocular lens (IOL) implant in eyes with prior trabeculectomy. DESIGN:Retrospective observational case-control study. METHODS:The study compared eyes that underwent phacoemulsification with IOL implant at least 3 months post-trabeculec...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2012.11.023
更新日期：2013-05-01 00:00:00
abstract：:A 6-year-old boy with a visual acuity of 6/30 (20/100) in each eye had a diffuse corneal epithelial disruption that was most severe in the interpalpebral area. Corneal anesthesia was demonstrated with the Cochet-Bonnet aesthesiometer. Artificial tears, lubricant ointments, and taping of the eyelids were unsuccessful i...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)77729-3
更新日期：1978-03-01 00:00:00
abstract：PURPOSE:To report a case of presumed congenital hypertrophy of the retinal pigment epithelium in the fovea of an 88-year-old woman in the setting of geographic atrophy from age-related macular degeneration. DESIGN:Observational case report. METHODS:An 88-year-old woman was examined. RESULTS:Best-corrected visual acu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01845-7
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:To describe a case of capsular bag distention syndrome with opaque contents noted 5 years after intraocular lens implantation. METHODS:A 66-year-old man underwent phacoemulsification after circular capsulorhexis and intraocular lens implantation in the left eye. Five years later, the posterior capsule was vaul...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)80195-0
更新日期：1998-04-01 00:00:00
abstract：:We compared the intraocular pressure in 150 urban household contacts of patients with Hansen's disease and 132 endemic control subjects from an urban population in Karachi, Pakistan, who were matched in regard to race, age, gender, and socioeconomic status. The mean intraocular pressure in the upright position was 12....
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71861-6
更新日期：1992-10-15 00:00:00
abstract：:In 84 cases of keratoplasty, all patients had densely vascularized corneas and a history of prior exposure to HLA antigens by pregnancy, blood transfusion, or previous transplantation. Donors were selected on the basis of a negative crossmatch to avoid donor antigens to which the recipient was preimmunized. The overal...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(78)90174-5
更新日期：1978-11-01 00:00:00
abstract：PURPOSE:This study compared the outcomes after Descemet's membrane endothelial keratoplasty (DMEK) in pseudophakic patients with the outcomes after DMEK combined with cataract surgery (triple-DMEK) in patients with Fuchs' endothelial dystrophy (FED). DESIGN:Retrospective, single-institution, interventional, consecutiv...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.05.003
更新日期：2020-10-01 00:00:00
abstract：:In a retrospective review from 1972 through 1987 of patients with microbial keratitis, fungal infection occurred in four (4%) of 90 cosmetic or aphakic contact lens wearers and in four (27%) of 15 patients using a therapeutic soft contact lens. Predisposing factors included improper lens care by the refractive lens we...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(88)90705-2
更新日期：1988-12-15 00:00:00
abstract：:Twenty-two fine needle (30 gauge) aspirations were performed in eyes enucleated for the clinical diagnosis of melanoma. Cytologic preparations were evaluated for adequacy of material, and needle tracts were evaluated for tumor implantation. A scleral marking method was used to identify all needle tracts. The number of...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(88)90248-6
更新日期：1988-05-15 00:00:00
abstract：PURPOSE:To describe the clinical features and complications of diabetic retinopathy, visual acuity, and number of repeat treatments after panretinal photocoagulation for proliferative diabetic retinopathy in a tertiary care center. METHODS:A cohort study was conducted with data collection from medical records of patie...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00322-0
更新日期：2000-02-01 00:00:00
abstract：PURPOSE:To characterize spontaneous dislocation of the fluocinolone acetonide sustained release implant (Retisert; Bausch & Lomb) drug pellet from its strut. DESIGN:Retrospective, observational case series. METHODS:The medical records of 224 patients in whom 407 fluocinolone acetonide implants were placed by either o...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2015.01.031
更新日期：2015-05-01 00:00:00
abstract：:I used a soft-tip suction needle during a vitrectomy procedure to life glass foreign bodies away from the retina so they could be more easily and safely grasped with foreign-body extraction forceps. The use of the instrument reduces the chance of inadvertent scraping of glass fragments or instruments against the retin...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75958-6
更新日期：1978-02-01 00:00:00
abstract：PURPOSE:To determine whether patients with primary open-angle glaucoma have an increase in size thresholds, prolongation of reaction times, and greater localization errors to random dot motion stimuli than normal subjects. METHODS:Motion perimetry, a computer graphics method of visual field testing, quantitates a subj...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72205-6
更新日期：1995-11-01 00:00:00
abstract：PURPOSE:To report a surgical procedure for excising subfoveal neovascular membranes and translocating the fovea in an attempt to maintain the function of the sensory retina to preserve central vision, based on the technique of macular relocation. METHODS:Three patients with subfoveal neovascular membranes underwent su...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70479-9
更新日期：1996-11-01 00:00:00
abstract：PURPOSE:To investigate the rate of progressive visual field (VF) loss and associated factors for structural or functional progression in preperimetric open-angle glaucoma (OAG). DESIGN:Longitudinal, observational study. METHODS:We included 127 eyes of 127 preperimetric OAG patients who were treated with topical medic...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.10.010
更新日期：2015-01-01 00:00:00
abstract：:A survey in Arkansas of 14 cases of ocular injuries caused by the explosion of Class C fireworks showed significant, and possibly permanent, visual loss in five men. The most common injuries, corneal abrasion and hyphema, occurred in nine male patients with no residual ocular damage. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90621-2
更新日期：1975-03-01 00:00:00
abstract：PURPOSE:To evaluate corneal higher-order aberrations induced by overnight orthokeratology for myopia. DESIGN:Prospective, noncomparative, consecutive, interventional case series. METHODS:A prospective study was conducted in 64 eyes of 39 patients with overnight orthokeratology for myopia, who were followed up for at ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.10.006
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:To report a case of progressive necrotizing fasciitis of the face following acute dacryocystitis. DESIGN:Interventional case report. METHODS:A 60-year-old woman presented with left acute dacryocystitis with abscess formation that had ruptured; a small wound remained. Erythematous swelling of the left eyelid a...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00089-8
更新日期：2003-07-01 00:00:00
abstract：PURPOSE/METHODS:By fundus photography and histopathologic examination, we documented a case of early endogenous Aspergillus endophthalmitis in a 29-year-old man after lung transplantation. RESULTS/CONCLUSIONS:The clinical and histopathologic features of this case are consistent with those of previous case reports of e...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73829-2
更新日期：1995-01-01 00:00:00
