The association of neuroleptic sensitivity in Lewy body disease with a false positive clinical diagnosis of Creutzfeldt-Jakob disease.

abstract：OBJECTIVES:Since plasma protein binding of tricyclic antidepressants may be relevant to treatment effects and can be influenced by age-associated factors, we examined both plasma ultrafiltrate and total concentrations of nortriptyline (NT) in patients and compared these to age. We hypothesized negative associations wit...

journal_title：International journal of geriatric psychiatry

authors： Young RC,Dhar AK,Hull J,Kakuma T,Alexopoulos GS

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:It is unknown to what extent depression and cognitive dysfunction are related in subjects with dementia. A limitation of earlier studies is that only general measures of depression have been studied. METHODS:In a sample of 60 subjects with dementia according to DSM-III-R criteria depressive symptoms were di...

journal_title：International journal of geriatric psychiatry

authors： Janzing JG,Naarding P,Eling PA

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Acetyl Cholinesterase Inhibitors (AChEIs) have been in clinical use for the past five years in the UK for the symptomatic treatment of Alzheimer's disease (AD). There are few data on the patterns and predictors of response to AChEI therapy in routine clinical practice. We therefore investigated clinical vari...

journal_title：International journal of geriatric psychiatry

authors： Pakrasi S,Mukaetova-Ladinska EB,McKeith IG,O'Brien JT

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Neuropsychiatric symptoms (NPS) are a common feature of Alzheimer's disease (AD), resulting in particular AD endophenotypes. The common AD genetic risk factor apolipoprotein E (APOE) has been suggested underlying these AD endophenotypes. METHODS:APOE genotyping, a comprehensive geriatric assessment (CGA), a...

journal_title：International journal of geriatric psychiatry

authors： D'Onofrio G,Panza F,Seripa D,Sancarlo D,Paris F,Cascavilla L,Urbano M,Gravina C,Fontana A,Solfrizzi V,Pellegrini F,Pilotto A

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The goal of the current study was to investigate psychological resilience in the older adults (>64 years) compared with that of the young ones (<26 years). METHODS:Questionnaire measures of depression, hopelessness, general health and resilience were administered to the participants. The resilience measure ...

journal_title：International journal of geriatric psychiatry

authors： Gooding PA,Hurst A,Johnson J,Tarrier N

更新日期：2012-03-01 00:00:00

abstract：:Less than one-tenth of all population-based research into dementia is directed towards the two-thirds or more of cases living in developing parts of the world. The 10/66 Dementia Research Group has been formed to redress this imbalance, encouraging active research collaboration between centres in different developing ...

journal_title：International journal of geriatric psychiatry

authors： Prince M

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:In this paper we investigated the question, how do older women who drink moderate amounts of alcohol differ from those who do not drink on measurements of cognitive function, memory, affect and health? METHODS:The nonprobability sample of female participants (n=182) averaged 75 years of age and had a Mini Me...

journal_title：International journal of geriatric psychiatry

authors： Zimmerman T,McDougall GJ Jr,Becker H

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:The oldest old are prone to develop delirium. Studies into risk factors for delirium have been carried out predominantly in younger age groups. The aim of this population-based follow-up study was to investigate the risk factors for delirium requiring medical attention and subsequent prognosis in the non-dem...

journal_title：International journal of geriatric psychiatry

authors： Rahkonen T,Eloniemi-Sulkava U,Halonen P,Verkkoniemi A,Niinistö L,Notkola IL,Sulkava R

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Scales measuring cognitive and executive functions are integral to the assessment and management of patients with suspected cognitive impairment. Some of the most commonly used cognitive tests are now subject to copyright restrictions. Furthermore, no existing scale assesses both executive and cognitive abil...

journal_title：International journal of geriatric psychiatry

authors： Burns A,Harrison JR,Symonds C,Morris J

更新日期：2020-10-29 00:00:00

abstract：OBJECTIVE:To examine whether intensive care unit (ICU) admission is independently associated with increased risk of major depression in patients with diabetes. METHODS:This prospective cohort study included 3596 patients with diabetes enrolled in the Pathways Epidemiologic Follow-Up Study, of whom 193 had at least one...

journal_title：International journal of geriatric psychiatry

authors： Davydow DS,Hough CL,Russo JE,Von Korff M,Ludman E,Lin EH,Ciechanowski P,Young B,Oliver M,Katon WJ

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Past research has demonstrated that there is a high level of depression among older people, particularly for those with cognitive impairment and those in residential care. The current study was designed to determine the prevalence of depression among older people in hostels with cognitive impairment using a ...

journal_title：International journal of geriatric psychiatry

authors： McCabe MP,Davison T,Mellor D,George K,Moore K,Ski C

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:Dementia is the most common neurological disease in older adults; headaches, including migraines, are the most common neurological disorder across all ages. The objective of this study was to explore the relationship between migraines and dementia, including Alzheimer's disease (AD) and vascular dementia (Va...

journal_title：International journal of geriatric psychiatry

authors： Morton RE,St John PD,Tyas SL

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:Scientific literature has identified different vulnerability factors associated to abuse in people with dementia (PWD), but little is known about the psychosocial protective variables against abuse. The main objective of this study is to investigate a set of caregiver and patient factors linked to abuse-relat...

journal_title：International journal of geriatric psychiatry

authors： Serra L,Contador I,Fernández-Calvo B,Ruisoto P,Jenaro C,Flores N,Ramos F,Rivera-Navarro J

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:The recruitment and adherence status of randomized controlled trials (RCTs) for population with mild cognitive impairment (MCI) are little known. We aimed to explore the RCT recruitment and adherence status and factors associated with these among MCI patients. METHODS:We searched MEDLINE, EMBASE, Cochrane L...

journal_title：International journal of geriatric psychiatry

authors： Xu Z,Sun W,Zhang D,Wong SY

更新日期：2020-05-18 00:00:00

abstract：BACKGROUND:Apathy is defined as an important loss of motivation in all domains of daily functioning. Especially in old age, apathy might be a specific neuropsychiatric syndrome separate from depression. There are indications that apathy in elderly subjects is related to vascular disease. OBJECTIVE:To assess the relati...

journal_title：International journal of geriatric psychiatry

authors： van der Mast RC,Vinkers DJ,Stek ML,Bek MC,Westendorp RG,Gussekloo J,de Craen AJ

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To determine whether attentional impairments are reliable neuropsychological markers of delirium. METHOD:A prospective cohort of one hundred patients admitted for elective orthopaedic surgery, 70 years and over, and free of dementia were recruited from an Orthopaedic unit in a university teaching hospital. C...

journal_title：International journal of geriatric psychiatry

authors： Lowery DP,Wesnes K,Brewster N,Ballard C

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:There is limited literature around peer research in dementia. This study aims to identify the benefits, the risks and the practical challenges and to develop a model of good practice in peer research with people with dementia. METHODS:We searched on PsycInfo, PubMed and Google Scholar for empirical investig...

journal_title：International journal of geriatric psychiatry

authors： Di Lorito C,Birt L,Poland F,Csipke E,Gove D,Diaz-Ponce A,Orrell M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Depression frequently co-occurs with cognitive decline, but the nature of this association is unclear. We examined relations of late-life depressive symptom patterns to subsequent domain-specific cognitive changes. METHODS:Depressive symptoms were measured at up to 3 timepoints among 11,675 Nurses' Health S...

journal_title：International journal of geriatric psychiatry

authors： Gillis JC,Chang SC,Devore EE,Rosner BA,Grodstein F,Okereke OI

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The aim of the study is to investigate the performance of the clock drawing test as a screening tool for cognitive impairment in Huntington's disease (HD) mutation carriers. METHODS:The performance of the clock drawing test was assessed in 65 mutation carriers using the Shulman and the Freund scoring system...

journal_title：International journal of geriatric psychiatry

authors： Terwindt PW,Hubers AA,Giltay EJ,van der Mast RC,van Duijn E

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:This study examined the moderating effect of caregiver burden on the relationship between the health status of Alzheimer's disease (AD) patients and their use of institutional services (i.e., hospitalization, nursing home, and residential care). METHODS:Data were obtained at baseline and at 3, 6, and 9 month...

journal_title：International journal of geriatric psychiatry

authors： Miller EA,Rosenheck RA,Schneider LS

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The 10/66 Dementia Research Group developed and validated a culture and education fair battery of cognitive tests for diagnosis of dementia in population-based studies in low-income and middle-income countries including India. AIMS:This study examined the association between individual domains of the 10/66 ...

journal_title：International journal of geriatric psychiatry

authors： Krishna M,Beulah E,Jones S,Sundarachari R,A S,Kumaran K,Karat SC,Copeland JR,Prince M,Fall C

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:To summarise existing knowledge of outcomes of older hospital patients with cognitive impairment, including the type and frequency of outcomes reported, and the additional risk experienced by this patient group. METHODS:Integrative literature review. Health care literature databases, reports, and policy doc...

journal_title：International journal of geriatric psychiatry

authors： Fogg C,Griffiths P,Meredith P,Bridges J

更新日期：2018-06-26 00:00:00

abstract：OBJECTIVES:To investigate the relation of plasma levels of Abeta peptides (Abeta1-40 and Abeta1-42) and apolipoprotein E (APOE) genotype to dementia status, and the duration of Alzheimer's disease (AD) in adults with Down syndrome (DS). METHODS:Adults with DS were recruited from community settings and followed up for ...

journal_title：International journal of geriatric psychiatry

authors： Prasher VP,Sajith SG,Mehta P,Zigman WB,Schupf N

更新日期：2010-02-01 00:00:00

abstract：:Reduced N-acetyl aspartate (NAA) and increased myo-inositol (MI) levels have been reported in patients with dementia of Alzheimer type (DAT) in comparison with controls. We wished to assess the validity of these findings and to evaluate possible correlations of metabolite proportions with cognitive dysfunction in DAT....

journal_title：International journal of geriatric psychiatry

authors： Heun R,Schlegel S,Graf-Morgenstern M,Tintera J,Gawehn J,Stoeter P

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of the DementiAbility Methods: The Montessori Way (DMMW) on agitation in long-term care home residents with dementia. The activities using the DMMW are hypothesized to reduce agitation in terms of its frequency and disruptiveness to greater extent than structured social activities as...

journal_title：International journal of geriatric psychiatry

authors： Yuen I,Kwok T

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Vascular depression is an important conceptual and clinical concept. OBJECTIVE:To apply criteria which, in an ideal world, should be satisfied before an association between depression and vascular disease can be considered robust. METHOD:A literature review with discussion of findings in the light of recen...

journal_title：International journal of geriatric psychiatry

authors： Baldwin RC

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Day hospital (DH) care remains a core component of mental health services for older people. However, there has been an ongoing debate about the effectiveness and value for money of DHs in comparison to day centres (DC). AIM:The aim was to review the recent research on the effectiveness of day hospitals for ...

journal_title：International journal of geriatric psychiatry

authors： Hoe J,Ashaye K,Orrell M

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:Recent data suggests that statins have positive effects on cognition in older adults. Studies in patients with mood disorders have found contradicting positive and negative effects of statins on mood and cognition, with limited data in bipolar disorder (BD). The objective of this study was to assess the asso...

journal_title：International journal of geriatric psychiatry

authors： Rej S,Schulte SW,Rajji TK,Gildengers AG,Miranda D,Menon M,Butters MA,Mulsant BH

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between regular physical activity and the risk of incident dementia in older Japanese adults. METHODS:This was a retrospective cohort study performed in Okayama City, Japan. Overall, 51 477 older Japanese adults were followed from 2008 to 2014. A health checkup questionnaire was u...

journal_title：International journal of geriatric psychiatry

authors： Liu Y,Mitsuhashi T,Yamakawa M,Sasai M,Tsuda T,Doi H,Hamada J

更新日期：2019-10-01 00:00:00

abstract：UNLABELLED:Data on the prevalence of and risk factors for suicide ideation among older people in developing countries is lacking. OBJECTIVE:This study aimed to estimate if dementia and other mental disorders are associated with suicide ideation among the older people controlling for demographic and other suspected ris...

journal_title：International journal of geriatric psychiatry

authors： Borges G,Acosta I,Sosa AL

更新日期：2015-03-01 00:00:00