Abstract:
BACKGROUND:Surgical ventricular restoration (SVR) is an operation that demonstrates promise to improve outcomes for patients with left ventricular dysfunction. Current use and operative outcomes of SVR have come from centers of expertise, and operative risks of SVR in community practice are unknown. We sought to characterize the performance of SVR nationally and describe the acute risks of mortality and major morbidity plus predictors of adverse outcomes. METHODS:We identified patients undergoing an SVR procedure at US hospitals participating in the Society of Thoracic Surgeons (STS) National Cardiac Database from January 2002 to June 2004. Baseline characteristics, operative characteristics, clinical outcomes, and predictors of adverse procedural outcomes were analyzed. RESULTS:There were 731 patients who underwent SVR at 141 of STS's 576 hospitals, and 20 centers performed 10 SVR procedures or more. The operative mortality was 9.3%; reoperation in 14.1%, stroke in 3.3%, renal failure in 8.1%, and prolonged ventilation in 21.5%. Combined death or major complications occurred in 33.5%. Major predictors of this combined end point were age, female sex, creatinine > or = 2 mg/dL, insulin-dependent diabetes, myocardial infarction within 1 week, history of congestive heart failure, 3-vessel coronary disease, severe mitral insufficiency, and status of surgery. CONCLUSION:This study provides a first look at use and outcomes of SVR in a national sample. Although a quarter of STS sites are performing SVR, most have limited experience and perioperative events are somewhat higher than prior selected series. Further studies of SVR are needed to improve patient selection and procedural performance.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Hernandez AF,Velazquez EJ,Dullum MK,O'Brien SM,Ferguson TB,Peterson EDdoi
10.1016/j.ahj.2006.01.016subject
Has Abstractpub_date
2006-09-01 00:00:00pages
494-9issue
3eissn
0002-8703issn
1097-6744pii
S0002-8703(06)00119-0journal_volume
152pub_type
杂志文章abstract:BACKGROUND:While pharmacologic stress single photon emission computed tomography myocardial perfusion imaging (SPECT-MPI) is used for noninvasive evaluation of patients who are unable to perform treadmill exercise, its impact on net reclassification improvement (NRI) of prognosis is unknown. METHODS:We evaluated the p...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2016.01.012
更新日期:2016-04-01 00:00:00
abstract::Eight patients with multifocal atrial tachycardia received 7 to 12 gm of magnesium sulfate intravenously over a 5-hour period. Potassium supplements were given initially or added later. Initial arterial blood gases showed mean pH 7.48 +/- 0.03, PcO2 39.7 torr, PO2 72 torr, HCO-3 29.8 +/- 4.5 mEq/L, and base excess 6.8...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(85)90458-2
更新日期:1985-10-01 00:00:00
abstract:BACKGROUND:To date, considerable controversy exists on the prognostic significance of morphometric endomyocardial biopsy findings in patients with idiopathic dilated cardiomyopathy (IDC). METHODS:Quantitative analyses of interstitial structured tissue, myofibril volume fraction, and myocytic fiber diameters of left ve...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/S0002-8703(03)00148-0
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:In 10,001 patients with stable coronary artery disease (CAD) enrolled in the Treating to New Targets (TNT) trial, 80 mg/d of atorvastatin (high-dose regimen) reduced the composite primary end point of death from CAD, nonfatal myocardial infarction, resuscitation from cardiac arrest, or stroke by 22% relative...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2008.05.032
更新日期:2008-10-01 00:00:00
abstract::A-II exerts its activity on various target tissues by binding to its receptors. The discovery of local RASs and A-II receptors within various tissues has generated interest in the clinical usefulness of RAS inhibition by directly blocking the action of A-II at the receptor level. Different A-II receptor subtypes have ...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(94)90061-2
更新日期:1994-05-01 00:00:00
abstract::High degree AV block occurred in 144 of 843 patients consecutively admitted because of acute inferior myocardial infarction and was associated with more extensive myocardial damage and a higher mortality rate, as compared to those without AV block. Patients with power failure at the time of appearance of high degree A...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(80)90308-7
更新日期:1980-01-01 00:00:00
abstract::In January 1997, experts from the United States, Europe, and Japan gathered at Stanford University to review their collective experience with intracoronary and noncoronary stenting and to identify and prioritize issues requiring further clinical investigation. This report summarizes the discussions that took place dur...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/s0002-8703(98)70004-3
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:Few telemedicine programs have undergone cost analyses, impeding their implementation into practice. We report on the economic analysis of a nurse-administered intervention designed to improve blood pressure control among hypertensive veterans. METHODS:We randomized hypertensive patients at the Durham Veter...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2010.05.024
更新日期:2010-08-01 00:00:00
abstract::Three hundred post infarction participants who had received type A behavioral counseling in the Recurrent Coronary Prevention Project, (RCPP) agreed to be followed for 1 additional year after stopping 4.5 years of continuous type A behavioral counseling. One hundred fourteen participants who had served for 4.5 years a...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-8703(87)90742-3
更新日期:1987-09-01 00:00:00
abstract:BACKGROUND:The LaFarge equation is the most commonly used equation to estimate oxygen consumption (Vo(2)) in patients of all ages with congenital heart disease, although it was generated in patients older than 3 years. We sought to determine the validity of the LaFarge equation in estimating Vo(2) in children younger t...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2010.04.003
更新日期:2010-07-01 00:00:00
abstract:CLINICAL SCENARIO:A 67-year-old man is referred to your cardiology clinic complaining of worsening angina and dyspnea on exertion. Physical examination reveals a harsh grade IV/VI late-peaking crescendo-decresendo systolic murmur, loudest at the upper sternal border. The aortic closure sound is diminished. Echocardiogr...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.05.031
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:The type of practitioners who use the standard exercise test is changing. Once a tool of the cardiologist, the standard exercise test is now being performed by internists and other noncardiologists. Because this change could be facilitated by computerization similar to the computerized interpretation program...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/s0002-8703(98)70233-9
更新日期:1998-09-01 00:00:00
abstract::Cardiovascular anomalies are a frequently reported feature of the fetal alcohol syndrome, but only rarely have such children been catheterized. This article fully described the cardiac anomaly in two infants with this syndrome. The malformations found in both cases include a ventricular septal defect, and the rather u...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(79)90290-4
更新日期:1979-11-01 00:00:00
abstract::Repair of coarctation of the aorta may not prevent the subsequent development of elevated systemic blood pressure at rest or with exercise. The correlates of late postoperative resting systolic blood pressure and maximal exercise systolic blood pressure levels were investigated in a retrospective study of 42 patients ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(87)90277-8
更新日期:1987-02-01 00:00:00
abstract::We evaluated the usefulness of peripherally injected sonicated albumin microbubbles in transesophageal echo-Doppler cardiographic assessment of the left atrial appendage in 19 patients (age 61 +/- 19 [range 21 to 86] years; 12 [63%] women). Multiplane transesophageal echocardiography was performed before and after int...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(97)70180-7
更新日期:1997-04-01 00:00:00
abstract::The long-term efficacy and safety of flecainide (100 to 200 mg twice a day) were evaluated in 21 patients with high-grade, chronic ventricular arrhythmias who responded to and tolerated flecainide at a preliminary evaluation (200 mg, single oral dose). Antiarrhythmic response was evaluated at 3 days and 3, 6, 12, 18, ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(89)90404-3
更新日期:1989-06-01 00:00:00
abstract::Left ventricular (LV) outflow obstruction may result from retaining the anterior mitral leaflet when a mitral prosthesis is inserted in the mitral anulus. We retrospectively reviewed the echocardiograms (two-dimensional Doppler and Doppler color flow imaging, or transesophageal with color flow imaging) obtained in sev...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)91005-8
更新日期:1991-08-01 00:00:00
abstract:BACKGROUND:The objective was to report recent trends in the incidence, adoption of evidence-based treatment, and clinical outcomes for first-time hospitalization for acute myocardial infarction. METHODS:This is a large retrospective population-based cohort study using medical administrative data (International Classif...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2013.08.026
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Despite advances in treatment of cardiogenic shock (CS), the incidence of this serious complication of acute ST-elevation myocardial infarction (STEMI) has stayed relatively constant, and rates of mortality, although somewhat improved in recent decades, remain dauntingly high. Although both percutaneous coro...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2009.10.035
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Statins (3-hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors) are known to reduce mortality and cardiac events in patients with coronary artery disease who have not progressed to left ventricular systolic dysfunction (LVSD) and/or heart failure (HF). This study investigated the effect of changes in s...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2007.01.029
更新日期:2007-04-01 00:00:00
abstract::Since many patients with chest pain cannot exercise adequately, an alternative stress would be useful to evaluate coronary reserve. We studied the physiologic responses to epinephrine to assess its potential. We report on 39 patients with chest pain. Doses from 0.03 to 0.30 micrograms/kg/min were administered intraven...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(83)90477-5
更新日期:1983-04-01 00:00:00
abstract::Patients experiencing out-of-hospital cardiac arrest (OHCA) without ST-segment elevation are a heterogenic group with a variety of underlying causes. Up to one-third of patients display a significant coronary lesion compatible with myocardial infarction as OHCA trigger. There are no randomized data on patient selectio...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2018.12.005
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Stroke is a rare but serious event that complicates the course of patients with acute coronary syndromes (ACS). The type, outcome, and risk factors of stroke occurring in stabilized patients with ACS have not been previously reported. METHODS:We evaluated stroke incidence, subtypes, and outcomes, in additio...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2004.01.028
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:The presence of depression after an acute coronary syndrome (ACS) is associated with worse prognosis and lower adherence to risk-reducing behaviors. We reported earlier that an enhanced depression care intervention reduces depression symptoms and major adverse cardiac events. This study evaluates the impact ...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2012.07.024
更新日期:2012-10-01 00:00:00
abstract::Flosequinan is an oral arterial and venous vasodilator that is currently under investigation for the treatment of congestive heart failure. The effects of flosequinan on ventricular performance and myocardial contractility were studied in 10 patients with severe congestive heart failure during right and left cardiac c...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90723-u
更新日期:1991-02-01 00:00:00
abstract:UNLABELLED:Antiarrhythmic agents enhance maintenance of sinus rhythm (SR) after direct current cardioversion (DCC) for atrial fibrillation but there are few comparative trials. BACKGROUND:The aims of the study were (1) to establish whether patients successfully cardioverted to SR are more likely to stay in SR over 6 m...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2005.09.009
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:Inflammation has been suggested as a factor in the initiation and maintenance of atrial fibrillation (AF). Several observational studies have suggested that statins, presumably through their anti-inflammatory properties, decrease the risk of AF. METHODS:We analyzed 2 large, randomized trials, PROVE IT-TIMI ...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2007.10.024
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:Experimental studies suggest that metabolic myocardial support by intravenous (IV) glucose, insulin, and potassium (GIK) reduces ischemia-induced arrhythmias, cardiac arrest, mortality, progression from unstable angina pectoris to acute myocardial infarction (AMI), and myocardial infarction size. However, tr...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2012.02.002
更新日期:2012-03-01 00:00:00
abstract::Studies were conducted in 15 patients with coronary artery disease to determine if the type of pacing used to induce an extrasystole had a bearing on subsequent postextrasystolic potentiation (PESP) and if the fact that these were evaluated in jeopardized or nonjeopardized portions of the ventricle altered the ability...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-8703(86)90149-3
更新日期:1986-02-01 00:00:00
abstract::Plasma cholesterol levels were measured in 15,892 participants of a cholesterol screening in Hartford, Connecticut. The screenees were typically health conscious as evidenced by the low prevalence of current cigarette smoking (12%). However, more than 25% of the men and 35% of the women over the age of 50 years had ch...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(89)90741-2
更新日期:1989-03-01 00:00:00