Abstract:
:A number of neuronal functions, including synaptic plasticity, depend on proper regulation of synaptic proteins, many of which can be rapidly regulated by phosphorylation. Neuronal activity controls the function of these synaptic proteins by exquisitely regulating the balance of various protein kinase and protein phosphatase activity. Recent understanding of synaptic plasticity mechanisms underscores important roles that these synaptic phosphoproteins play in regulating both pre- and post-synaptic functions. This review will focus on key postsynaptic phosphoproteins that have been implicated to play a role in synaptic plasticity.
journal_name
Pharmacol Therjournal_title
Pharmacology & therapeuticsauthors
Lee HKdoi
10.1016/j.pharmthera.2006.06.003subject
Has Abstractpub_date
2006-12-01 00:00:00pages
810-32issue
3eissn
0163-7258issn
1879-016Xpii
S0163-7258(06)00119-7journal_volume
112pub_type
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journal_title:Pharmacology & therapeutics
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journal_title:Pharmacology & therapeutics
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journal_title:Pharmacology & therapeutics
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journal_title:Pharmacology & therapeutics
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