Medical management of patients with brain tumors.

Abstract:

:The most common medical problems in brain tumor patients include the management of seizures, peritumoral edema, medication side effects, venous thromboembolism (VTE), fatigue and cognitive dysfunction. Despite their importance, there are relatively few studies specifically addressing these issues. There is increasing evidence that brain tumor patients who have not had a seizure do not benefit from prophylactic antiepileptic medications. Patients on corticosteroids are at greater risk of Pneumocystis jerovecii pneumonia and may benefit from prophylactic therapy. There is also growing evidence suggesting that anticoagulation may be more effective than inferior vena cava IVC) filtration devices for treating VTE in brain tumor patients and the risk of hemorrhage with anticoagulation is relatively small. Low-molecular weight heparin may be more effective than coumadin. Medications such as modafinil and methylphenidate have assumed an increasing role in the treatment of fatigue, while donepezil and memantine may be helpful with memory loss.

journal_name

J Neurooncol

authors

Wen PY,Schiff D,Kesari S,Drappatz J,Gigas DC,Doherty L

doi

10.1007/s11060-006-9193-2

subject

Has Abstract

pub_date

2006-12-01 00:00:00

pages

313-32

issue

3

eissn

0167-594X

issn

1573-7373

journal_volume

80

pub_type

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