In vivo lumbar erector spinae oxygenation and blood volume measurements in healthy men during seated whole-body vibration.

abstract：:This study examined whether left ventricular function was reduced during 3 h of semi-recumbent ergometer cycling at 70% of maximal oxygen uptake while preload to the heart was maintained via saline infusion. Indices of left ventricular systolic function (end-systolic blood pressure-volume relationship, SBP/ESV) and di...

journal_title：Experimental physiology

authors： Dawson EA,Shave R,Whyte G,Ball D,Selmer C,Jans Ø,Secher NH,George KP

更新日期：2007-03-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? This review is principally concerned with results from studies of the pulmonary vasculature in humans, particularly in relation to hypoxia and rare diseases that affect oxygen sensing. What advances does it highlight? This review highlights the degree to which the hypoxia-...

journal_title：Experimental physiology

authors： Frise MC,Robbins PA

更新日期：2015-11-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Are the urinary concentrations of NO and ATP, and their metabolites, associated with the severity of symptoms of overactive bladder? What is the main finding and its importance? The urinary ratios of [ATP/NO], [ADP/NO] and a combination of these, [ATP/Cr*ADP/Cr]/...

journal_title：Experimental physiology

authors： Firouzmand S,Young JS

更新日期：2020-06-01 00:00:00

abstract：:What is the topic of this review? This article presents emerging evidence for heightened carotid body chemoreflex activity as a major driver of sympathetic activation and hypertension in sleep apnoea patients. What advances does it heighlight? This article discusses the recent advances on cellular, molecular and epige...

journal_title：Experimental physiology

authors： Prabhakar NR

更新日期：2016-08-01 00:00:00

abstract：:After food is ingested, nutrients pass through the gastrointestinal tract, stimulating the release of a range of peptide hormones. Among their many local, central and peripheral actions, these hormones act to mediate glucose metabolism and satiety. Indeed, it is the modification of gut hormone secretion that is consid...

journal_title：Experimental physiology

authors： Parker HE,Gribble FM,Reimann F

更新日期：2014-09-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Does the muscle metaboreflex affect the ratio of left ventricular contraction/relaxation rates and does heart failure impact this relationship. What is the main finding and its importance? The effect of muscle metaboreflex activation on the ventricular relaxation...

journal_title：Experimental physiology

authors： Mannozzi J,Massoud L,Kaur J,Coutsos M,O'Leary DS

更新日期：2020-11-23 00:00:00

abstract：:The role of testosterone (T) in the regulation of cardiovascular function in females is not well understood. Our goal was to examine the effect of T on cardiomyocyte biology by measuring sarcomere shortening/relaxation and intracellular calcium cycling in adult female Sprague-Dawley rats. The rats were divided into th...

journal_title：Experimental physiology

authors： Beesley RD,Palmer BM,Casson PR,Toth MJ

更新日期：2013-01-01 00:00:00

abstract：:Cardiovascular arousal is associated with patterned cortical activity changes. Head-down-tilt bed rest (HDBR) dimishes the baroreflex-mediated cardiac control. The present study tested the hypothesis that HDBR deconditioning would modify the forebrain organization for heart rate (HR) control during baroreflex unloadin...

journal_title：Experimental physiology

authors： Shoemaker JK,Usselman CW,Rothwell A,Wong SW

更新日期：2012-12-01 00:00:00

abstract：:Branched fibres are a well-documented phenomenon of regenerating skeletal muscle. They are found in the muscles of boys with Duchenne muscular dystrophy (DMD), a severe condition of progressive muscle wasting caused by an absence of the sarcolemmal protein dystrophin, and in the muscles of the mdx mouse, an animal mod...

journal_title：Experimental physiology

authors： Chan S,Head SI

更新日期：2011-06-01 00:00:00

abstract：:What is the central question of this study? Failure to terminate apnoea and arouse is likely to contribute to sudden infant death syndrome (SIDS). Serotonin is deficient in the brainstems of babies who died of SIDS. Therefore, we tested the hypothesis that serotonin in the nucleus of the solitary tract (NTS) would sho...

journal_title：Experimental physiology

authors： Donnelly WT,Bartlett D Jr,Leiter JC

更新日期：2016-07-01 00:00:00

abstract：:Three experiments were performed to see whether cardiac neurons contribute to the intrinsic control of heart rate in right atria of adult rats. The intrinsic heart rate response (IRR) was examined by raising right atrial pressure from 2 to 8 mmHg for 3 min. In isolated preparations of the right atrium, the IRR was not...

journal_title：Experimental physiology

authors： Wilson SJ,Bolter CP

更新日期：2002-11-01 00:00:00

abstract：:The aim of the present study was to assess the influence of body posture on post-submaximal exercise parasympathetic reactivation and to examine whether this influence was preserved under a heightened sympathetic background. On four occasions, eleven moderately trained subjects (22.1 +/- 3.0 years old) performed, in r...

journal_title：Experimental physiology

authors： Buchheit M,Al Haddad H,Laursen PB,Ahmaidi S

更新日期：2009-07-01 00:00:00

abstract：:The nucleus tractus solitarii (NTS) is a key central link in control of multiple homeostatic reflexes. A number of studies have demonstrated that exogenous and endogenous nitric oxide (NO) within NTS regulates visceral function, but further understanding of the role of NO in the NTS is hampered by the lack of informat...

journal_title：Experimental physiology

authors： Wang S,Paton JF,Kasparov S

更新日期：2007-03-01 00:00:00

abstract：:Spermine is a low molecular weight polyamine involved in the postnatal maturation of the gut. When it is administered orally to suckling rats, it induces maturation of the intestinal tract (liver, pancreas and small intestine). Here we show that this polyamine is able to induce precocious intestinal and splenic develo...

journal_title：Experimental physiology

authors： Jolois O,Peulen O,Collin S,Simons M,Dandrifosse G,Heinen E

更新日期：2002-01-01 00:00:00

abstract：:The glucagon response to insulin-induced hypoglycaemia was tested in rats that had been pinealectomised (Px), pinealectomised and fitted with melatonin implants (Px + MLT), or sham-operated (SO). The glucagon response to hypoglycaemia observed in SO rats (216 +/- 27 pg x ml(-1) at baseline versus 397 +/- 35 pg x ml(-1...

journal_title：Experimental physiology

authors： Kosa E,Maurel D,Siaud P

更新日期：2001-09-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Although peripheral blood haematopoietic stem and progenitor cells are potentially important in regeneration after acute myocardial infarction, their self-renewal ability in the post-acute phase has not yet been addressed. What is the main finding and its importa...

journal_title：Experimental physiology

authors： Kröpfl JM,Spengler CM,Frobert A,Ajalbert G,Giraud MN

更新日期：2018-01-01 00:00:00

abstract：:The physiological mechanisms contributing to sex differences following myocardial infarction (MI) are poorly understood. Given the strong relationship between sympathetic nerve activity (SNA) and outcome, we hypothesized there may be a sex difference in SNA responses to MI. In anaesthetized, open-chest male, female an...

journal_title：Experimental physiology

authors： Pinkham MI,Guild SJ,Malpas SC,Barrett CJ

更新日期：2012-09-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? This review provides a comprehensive overview of Nox5 from basic biology to human disease and highlights unique features of this Nox isoform What advances does it highlight? Major advances in Nox5 biology relate to crystallization of the molecule and new insights into the ...

journal_title：Experimental physiology

authors： Touyz RM,Anagnostopoulou A,Rios F,Montezano AC,Camargo LL

更新日期：2019-05-01 00:00:00

abstract：NEW FINDINGS:What is the central question of the study? What are the effects of age and fitness on the vascular response to acute inflammation in younger and older adults? What is the main finding and its importance? In older adults, cardiorespiratory fitness level has a differential impact on endothelial function afte...

journal_title：Experimental physiology

authors： Schroeder EC,Lane-Cordova AD,Ranadive SM,Baynard T,Fernhall B

更新日期：2018-06-01 00:00:00

abstract：:What is the central question of this study? Myocardial ischaemia-reperfusion (I/R) injury causes interference in the systemic circulation and damages not only the heart but also several vital organs, including the brain. Recently, a novel peptide called humanin has been shown to exert potent neuroprotective effects. H...

journal_title：Experimental physiology

authors： Kumfu S,Charununtakorn ST,Jaiwongkam T,Chattipakorn N,Chattipakorn SC

更新日期：2016-06-01 00:00:00

abstract：:Chronically hypoxic (CH) and normoxic control rats were used to assess the action of S9581, a water-soluble analogue of almitrine bismesylate. S9581 increased ventilation (Ve) by 34% in control and 20% in CH rats. During acute hypoxia Ve was raised and S9581 caused a further increase of 20% in both groups. Low doses o...

journal_title：Experimental physiology

authors： Bee D,Emery CJ,Howard P

更新日期：1992-11-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Does recreational cold exposure result in cold sensitivity and is this associated with endothelial dysfunction and impaired sensory thermal thresholds? What is the main finding and its importance? Previous cold exposure was correlated with cold sensitivity of the...

journal_title：Experimental physiology

authors： Eglin CM,Costello JT,Tipton MJ,Massey H

更新日期：2021-01-01 00:00:00

abstract：:This work was undertaken to study the effect of pectin feeding on the expression level, cellular localization and functional activity of monocarboxylate transporter 1 (MCT1) in the gastrointestinal tract of rats. The results indicated that MCT1 protein level was significantly increased along the entire length of the g...

journal_title：Experimental physiology

authors： Kirat D,Kondo K,Shimada R,Kato S

更新日期：2009-04-01 00:00:00

abstract：:It has been shown previously that the amplitudes of the harmonic components of the pulse spectrum vary in specific patterns when the arteries leading to different organs are ligated, with the variations in the harmonics being linearly additive. Since ligation can be regarded as a vast increase in organ resistance, the...

journal_title：Experimental physiology

authors： Hsu TL,Chao PT,Hsiu H,Wang WK,Li SP,Wang YY

更新日期：2006-01-01 00:00:00

abstract：:Although numerous studies have recently implicated the calcineurin-nuclear factor of activated T-cells (Cn-NFAT) signalling pathway in the regulation of activity-dependent fibre type switching in adult mammalian skeletal muscles, little is known about the endogenous expression of NFAT proteins in the various fibre typ...

journal_title：Experimental physiology

authors： Mutungi G

更新日期：2008-03-01 00:00:00

abstract：:It is unclear whether measurement of limb or conduit artery blood flow during recovery from exercise provides an accurate representation of flow to the muscle capillaries where gas exchange occurs. To investigate this, we: (a) examined the kinetic responses of femoral artery blood flow (QFA), estimated muscle capillar...

journal_title：Experimental physiology

authors： Harper AJ,Ferreira LF,Lutjemeier BJ,Townsend DK,Barstow TJ

更新日期：2008-10-01 00:00:00

abstract：:We have examined the surface ultrastructure and morphological characteristics of leucocytes obtained from control rats breathing air and rats made acutely hypoxic (breathing 6% O2, for 30 min). Striking ultrastructural and morphological changes occurred in the leucocytes of hypoxic rats. These changes included the app...

journal_title：Experimental physiology

authors： Mian R,Westwood D,Stanley P,Marshall JM,Coote JH

更新日期：1993-11-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What is the role of miR-143-3p during human dental pulp stem cell (hDPSC) differentiation. What is the main finding and its importance? miR-143-3p negatively regulates receptor activator of nuclear factor-κB (RANK). RANK ligand (RANKL) binds to RANK and stimulate...

journal_title：Experimental physiology

authors： Yang C,Jia R,Zuo Q,Zheng Y,Wu Q,Luo B,Lin P,Yin L

更新日期：2020-05-01 00:00:00

abstract：:Progressive asphyxia, produced by a prolonged voluntary breath hold (end-expiratory apnoea), evokes large bursts of muscle sympathetic nerve activity (MSNA). These bursts increase in amplitude until the asphyxic break point is reached, at which point the bursts are inhibited. We tested the hypothesis that lung inflati...

journal_title：Experimental physiology

authors： Seitz MJ,Brown R,Macefield VG

更新日期：2013-02-01 00:00:00

abstract：:The present investigation was designed to examine whether calmodulin is involved in the inhibition of the ATP-sensitive K+ (K(ATP)) channel by glucagon-like peptide 1(7-36) amide (GLP-1) in mouse pancreatic beta-cells. Membrane potential, single channel and whole-cell currents through the K(ATP) channels, and intracel...

journal_title：Experimental physiology

authors： Ding WG,Kitasato H,Matsuura H

更新日期：2001-05-01 00:00:00