In vivo lumbar erector spinae oxygenation and blood volume measurements in healthy men during seated whole-body vibration.


:Exposure to whole-body vibration is implicated as one of the occupational risk factors for lower back disorders; however, its influence on the lumbar muscle physiology is still poorly understood. The objective of this study was to investigate the effects of backrest support and hand grip contractions on lumbar muscle oxygenation and blood volume responses during seated whole-body vibration using continuous dual-wave near-infrared spectroscopy. Thirteen healthy men were exposed to frequencies of 3, 4.5 and 6 Hz on a vibration simulator, in randomized order on separate days. Each day the duration of the protocol was 30 min. During the fifth minute of vibration 'with' and 'without' backrest support, participants performed maximal rhythmic hand grip contractions for 1 min. In general, erector spinae oxygenation and blood volume showed a trend to decrease with vibration exposure compared to the control condition. However, these responses were not influenced by the change in vibration frequency (P > 0.05). Sitting without backrest resulted in a greater decrease in oxygenation (by 27%, P = 0.02) and blood volume (by 11%, P = 0.05) than with backrest, implying a deficiency in oxygen supply owing to the sitting posture. Compared to the vibration-only condition, hand grip work decreased both oxygenation (by 22%, P = 0.003) and blood volume responses (by 13%, P = 0.04), suggesting that postural load due to prolonged sitting combined with physical activity during vibration might further burden paraspinal muscles. The influence of adipose tissue thickness of the lumbar muscle on optically derived oxygenation and blood volume changes was inconclusive.


Exp Physiol


Experimental physiology


Maikala RV,Bhambhani YN




Has Abstract


2006-09-01 00:00:00














  • Differential aerobic exercise-induced changes in plasma aldosterone between African Americans and Caucasians.

    abstract::Aldosterone influences the kidney's regulation of blood pressure (BP), but aldosterone can contribute to the pathogenesis of hypertension. Blood pressure is reduced with aerobic exercise training (AEX), but the extent to which plasma aldosterone (PA) levels change is unclear. The purpose of this study was to determine...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Jones JM,Dowling TC,Park JJ,Phares DA,Park JY,Obisesan TO,Brown MD

    更新日期:2007-09-01 00:00:00

  • Experimental increase of blood glucose alters resting state EEG measures of excitation-inhibition balance.

    abstract:NEW FINDINGS:What is the central question of this study? Glucose is the dominant energy source for the brain. However, little is known about how glucose metabolism impacts the coordination of network activity in the brain in healthy adults. What is the main finding and its importance? We demonstrate that both alpha osc...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Walker CP,Buse J,Frohlich F

    更新日期:2021-01-28 00:00:00

  • Extracellular calcium chelation and attenuation of calcium entry decrease in vivo cholinergic-induced eccrine sweating sensitivity in humans.

    abstract:NEW FINDINGS:What is the central question of this study? Calcium is an important second messenger in eccrine sweating; however, whether modulation of extracellular Ca(2+) and Ca(2+) entry has the capacity to modulate sweat rate in non-glabrous human skin has not been explored. What is the main finding and its importanc...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Metzler-Wilson K,Sammons DL,Ossim MA,Metzger NR,Jurovcik AJ,Krause BA,Wilson TE

    更新日期:2014-02-01 00:00:00

  • Evidence for simultaneous bidirectional fluid flux across synovial lining in knee joints of anaesthetized rabbits.

    abstract::A recent model predicted a local synovial circulation of extravascular fluid in which capillary filtrate entered a joint cavity and fluid simultaneously drained out of the cavity via intercellular pathways distant from capillaries. Here, solutions of albumin (10-250 g l-1) were infused continuously into the knee joint...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: McDonald JN,Levick JR

    更新日期:1992-05-01 00:00:00

  • The effect of a hyposmotic shock on amino acid efflux from lactating rat mammary tissue: stimulation of taurine and glycine efflux via a pathway distinct from anion exchange and volume-activated anion channels.

    abstract::We have examined the effect of a hyposmotic shock, and thus cell swelling, upon the efflux of amino acids, SO4(2-) and I- from lactating mammary tissue. A hyposmotic challenge increased the efflux of taurine and glycine via a 4,4'-diisothiocyanatostilbene-2,2'- disulphonic acid (DIDS)-sensitive pathway. It appears tha...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Shennan DB,McNeillie SA,Curran DE

    更新日期:1994-09-01 00:00:00

  • Postprandial adjustments in renal phosphate excretion do not involve a gut-derived phosphaturic factor.

    abstract:NEW FINDINGS:What is the central question of this study? Does a previously hypothesized signalling mechanism, believed to detect postprandial increases in intestinal phosphate and that can stimulate the kidneys to rapidly excrete phosphate, operate under physiological conditions? What is the main finding and its import...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Lee GJ,Mossa-Al Hashimi L,Debnam ES,Unwin RJ,Marks J

    更新日期:2017-04-01 00:00:00

  • Are there more than two types of alpha-adrenoceptors involved in physiological responses?

    abstract::The application of the four main techniques available for examining the properties of alpha-adrenoceptors, gene coding, radioligand, biochemical and functional methods, has reinforced the earlier subclassification (alpha 1- and alpha 2-subtypes). These different techniques have not yet yielded subclassifications which...

    journal_title:Experimental physiology

    pub_type: 杂志文章,评审


    authors: Wilson VG,Brown CM,McGrath JC

    更新日期:1991-05-01 00:00:00

  • Changes in human and rat uterine phosphoethanolamine and taurine with pregnancy and parturition.

    abstract::Phosphoethanolamine and taurine have been identified in uterine extracts from rat and, for the first time, human tissue. The concentration of phosphoethanolamine [PEtn] determined by HPLC and 31P NMR spectroscopy, increased markedly (40%) within the first 6-12 h following parturition in rats, suggesting a role in invo...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Phoenix J,Wray S

    更新日期:1994-07-01 00:00:00

  • Contribution of joint and muscle afferents to position sense at the human proximal interphalangeal joint.

    abstract::Experiments were carried out to examine the perceived position of the human index finger about the proximal interphalangeal joint. In protocol I, the finger was moved from an intermediate position at velocities ranging from 200 deg/min to 2 deg/min, then held still at one of three positions. The subject's task was vis...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Ferrell WR,Craske B

    更新日期:1992-03-01 00:00:00

  • Acute and chronic effects of pancreatic glucagon on sugar transport across the brush-border and basolateral membranes of rat jejunal enterocytes.

    abstract::Preparations of isolated rat jejunal enterocyte and brush-border and basolateral membrane vesicles have been used to study the effects of a 15 min exposure of upper and mid-villus enterocytes to pancreatic glucagon on the initial, unidirectional phlorhizin-sensitive (brush border) transport of galactose and phlorhizin...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Debnam ES,Sharp PA

    更新日期:1993-03-01 00:00:00

  • Effect of whole body resistance training on arterial compliance in young men.

    abstract::The effect of resistance training on arterial stiffening is controversial. We tested the hypothesis that resistance training would not alter central arterial compliance. Young healthy men (age, 23 +/- 3.9 (mean +/- s.e.m.) years; n = 28,) were whole-body resistance trained five times a week for 12 weeks, using a rotat...

    journal_title:Experimental physiology

    pub_type: 临床试验,杂志文章


    authors: Rakobowchuk M,McGowan CL,de Groot PC,Bruinsma D,Hartman JW,Phillips SM,MacDonald MJ

    更新日期:2005-07-01 00:00:00

  • Long non-coding RNA activated by transforming growth factor-β promotes proliferation and invasion of cervical cancer cells by regulating the miR-144/ITGA6 axis.

    abstract:NEW FINDINGS:What is the central question of this study? This study was designed to investigate the molecular mechanism and biological roles of long non-coding RNA activated by transforming growth factor-β (lncRNA ATB) in the progression of cervical cancer. What is the main finding and its importance? Our study provide...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Zhu Y,Wu Y,Yang L,Dou X,Jiang J,Wang L

    更新日期:2019-06-01 00:00:00

  • Sustained postexercise vasodilatation and histamine receptor activation following small muscle-mass exercise in humans.

    abstract::A sustained postexercise vasodilatation, which is histamine receptor mediated, has been observed following single bouts of whole-body exercise, but the mechanisms that regulate activation of histamine receptors following exercise are undefined. Exploration of vasodilatation after small muscle-mass dynamic or resistanc...

    journal_title:Experimental physiology

    pub_type: 杂志文章,随机对照试验


    authors: Barrett-O'Keefe Z,Kaplon RE,Halliwill JR

    更新日期:2013-01-01 00:00:00

  • Sitting decreases endothelial microparticles but not circulating angiogenic cells irrespective of lower leg exercises: a randomized cross-over trial.

    abstract:NEW FINDINGS:What is the central question of this study? What are the cellular and molecular determinants of increased risk for cardiovascular disease from prolonged sitting? What is the main finding and its importance? Prolonged sitting, independent of calf raise interruption strategies, decreases microparticle counts...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Evans WS,Hanson ED,Shill DD,Landers-Ramos RQ,Stoner L,Willey Q,Credeur DP,Prior SJ

    更新日期:2020-08-01 00:00:00

  • Effect of body posture on postexercise parasympathetic reactivation in men.

    abstract::The aim of the present study was to assess the influence of body posture on post-submaximal exercise parasympathetic reactivation and to examine whether this influence was preserved under a heightened sympathetic background. On four occasions, eleven moderately trained subjects (22.1 +/- 3.0 years old) performed, in r...

    journal_title:Experimental physiology

    pub_type: 杂志文章,随机对照试验


    authors: Buchheit M,Al Haddad H,Laursen PB,Ahmaidi S

    更新日期:2009-07-01 00:00:00

  • Sympathoexcitatory response to peripheral chemoreflex activation is enhanced in juvenile rats exposed to chronic intermittent hypoxia.

    abstract::In the present study, we tested the hypothesis that chronic intermittent hypoxia (CIH) produces changes in the autonomic and respiratory responses to acute peripheral chemoreflex activation. To attain this goal, 3-week-old rats were exposed to 10 days of CIH (6% O(2) for 40 s at 9 min intervals; 8 h day(-1)). They wer...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Braga VA,Soriano RN,Machado BH

    更新日期:2006-11-01 00:00:00

  • Double-sigmoid model for fitting fatigue profiles in mouse fast- and slow-twitch muscle.

    abstract::We present a curve-fitting approach that permits quantitative comparisons of fatigue profiles obtained with different stimulation protocols in isolated slow-twitch soleus and fast-twitch extensor digitorum longus (EDL) muscles of mice. Profiles from our usual stimulation protocol (125 Hz for 500 ms, evoked once every ...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Cairns SP,Robinson DM,Loiselle DS

    更新日期:2008-07-01 00:00:00

  • The splanchnic anti-inflammatory pathway: could it be the efferent arm of the inflammatory reflex?

    abstract::What is the topic of this review? We review the current literature on the neural reflex termed the 'inflammatory reflex' that inhibits an excessive release of inflammatory mediators in response to an immune challenge. What advances does it highlight? The original model proposed that the inflammatory reflex is a vago-v...

    journal_title:Experimental physiology

    pub_type: 杂志文章,评审


    authors: Martelli D,Farmer DG,Yao ST

    更新日期:2016-10-01 00:00:00

  • Endothelial hypoxic preconditioning in rat hypoxic isolated aortic segments.

    abstract::Our aim was to analyse endothelial hypoxic preconditioning after hypoxia-reperfusion (HR). Endothelial functionality was analysed through the vasorelaxation responses to acetylcholine (Ach) and the level of serine1177 phosphorylated endothelial nitric oxide synthase (eNOS) (ser1177-eNOS) measured by Western blot in in...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Carrasco-Martín C,Alonso-Orgaz S,De la Pinta JC,Marques M,Macaya C,Barrientos A,González MM,García-Méndez A,Mateos-Cáceres PJ,Porres JC,Rico LA,López-Farré AJ

    更新日期:2005-07-01 00:00:00

  • Neuropeptidergic and autonomic control of the vasculature of the rat knee joint revealed by laser Doppler perfusion imaging.

    abstract::An imaging technique (laser Doppler perfusion imaging, LDI), based on measurement of backscattered Doppler-broadened laser radiation, was used to provide two-dimensional images of perfusion in the exposed rat knee joint capsule. In control animals, frequency-dependent constriction of knee joint blood vessels occurred ...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Karimian SM,McDougall JJ,Ferrell WR

    更新日期:1995-05-01 00:00:00

  • Effects of pinealectomy on glucagon responsiveness to hypoglycaemia induced by insulin injections in fed rats.

    abstract::The glucagon response to insulin-induced hypoglycaemia was tested in rats that had been pinealectomised (Px), pinealectomised and fitted with melatonin implants (Px + MLT), or sham-operated (SO). The glucagon response to hypoglycaemia observed in SO rats (216 +/- 27 pg x ml(-1) at baseline versus 397 +/- 35 pg x ml(-1...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Kosa E,Maurel D,Siaud P

    更新日期:2001-09-01 00:00:00

  • Effects of inspiratory muscle strength and inspiratory resistance on neck inspiratory muscle activation during controlled inspirations.

    abstract:NEW FINDINGS:What is the central question of this study? What factors influence the onset and magnitude of activation of the neck inspiratory muscles during inspiration? What is the main finding and its importance? Recruitment of the sternocleidomastoid and scalene muscles during inspiration, measured by means of surfa...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Washino S,Mankyu H,Kanehisa H,Mayfield DL,Cresswell AG,Yoshitake Y

    更新日期:2019-04-01 00:00:00

  • The inspired sine-wave technique: A novel method to measure lung volume and ventilatory heterogeneity.

    abstract:NEW FINDINGS:What is the central question of this study? We present a new non-invasive medical technology, the inspired sine-wave technique, which involves inhalation of sinusoidally fluctuating concentrations of a tracer gas. The technique requires only passive patient cooperation and can monitor different cardiorespi...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Bruce RM,Phan PA,Pacpaco E,Rahman NM,Farmery AD

    更新日期:2018-05-01 00:00:00

  • Interactions between maternal subtotal nephrectomy and salt: effects on renal function and the composition of plasma in the late gestation sheep fetus.

    abstract::Effects of altered maternal salt intake between 122 and 127 days gestation (term is 150 days) were studied in eight fetuses carried by ewes which had renal insufficiency caused by subtotal nephrectomy (STNxF) and seven fetuses carried by intact ewes (IntF). Plasma sodium and osmolality were increased in ewes with subt...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Boyce AC,Gibson KJ,Thomson CL,Lumbers ER

    更新日期:2008-02-01 00:00:00

  • Progress in therapy for Duchenne muscular dystrophy.

    abstract::Duchenne muscular dystrophy is a devastating muscular dystrophy of childhood. Mutations in the dystrophin gene destroy the link between the internal muscle filaments and the extracellular matrix, resulting in severe muscle weakness and progressive muscle wasting. There is currently no cure and, whilst palliative treat...

    journal_title:Experimental physiology

    pub_type: 杂志文章,评审


    authors: Fairclough RJ,Bareja A,Davies KE

    更新日期:2011-11-01 00:00:00

  • Absorption and intestinal catabolism of fatty acids in the rat: effect of chain length and unsaturation.

    abstract::Simultaneous portal blood absorption and intestinal mucosal catabolism of labelled fatty acids were investigated. Anaesthetized adult Wistar rats were infused intraduodenally either with 90 mumol of capric (C10:0), oleic (C18:1), linoleic (C18:2) or arachidonic (C20:4) 1-14C acids or with 30 mumol of each labelled fat...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Bernard A,Carlier H

    更新日期:1991-05-01 00:00:00

  • Involvement of calmodulin in glucagon-like peptide 1(7-36) amide-induced inhibition of the ATP-sensitive K+ channel in mouse pancreatic beta-cells.

    abstract::The present investigation was designed to examine whether calmodulin is involved in the inhibition of the ATP-sensitive K+ (K(ATP)) channel by glucagon-like peptide 1(7-36) amide (GLP-1) in mouse pancreatic beta-cells. Membrane potential, single channel and whole-cell currents through the K(ATP) channels, and intracel...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Ding WG,Kitasato H,Matsuura H

    更新日期:2001-05-01 00:00:00

  • Central and peripheral doses of cholecystokinin that inhibit feeding in pigs also stimulate vasopressin and cortisol release.

    abstract::The effects on vasopressin and cortisol secretion of centrally and peripherally administered cholecystokinin octapeptide (CCK) were investigated in conscious prepubertal pigs. Injection of 1.3 micrograms CCK into the lateral cerebral ventricle resulted in a sustained increase in plasma vasopressin after a latency of 5...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Parrott RF,Ebenezer IS,Baldwin BA,Forsling ML

    更新日期:1991-07-01 00:00:00

  • Role of the parasympathetic nervous system in cardioprotection by remote hindlimb ischaemic preconditioning.

    abstract::This investigation was designed to determine the participation of the vagus nerve and muscarinic receptors in the remote ischaemic preconditioning (rIPC) mechanism. New Zealand rabbits were anaesthetized, and the femoral artery was dissected. After 30 min of monitoring, the hearts were isolated and subjected to 30 min...

    journal_title:Experimental physiology

    pub_type: 杂志文章


    authors: Donato M,Buchholz B,Rodríguez M,Pérez V,Inserte J,García-Dorado D,Gelpi RJ

    更新日期:2013-02-01 00:00:00

  • Response of skeletal muscle mitochondria to hypoxia.

    abstract::This review explores the current concepts relating the structural and functional modifications of skeletal muscle mitochondria to the molecular mechanisms activated when organisms are exposed to a hypoxic environment. In contrast to earlier assumptions it is now established that permanent or long-term exposure to seve...

    journal_title:Experimental physiology

    pub_type: 杂志文章,评审


    authors: Hoppeler H,Vogt M,Weibel ER,Flück M

    更新日期:2003-01-01 00:00:00