Signaling from across the way: transactivation of VEGF receptors by HSPGs.

Abstract:

:Heparan sulfate proteoglycans (HSPGs) influence the signaling of many growth factors, and recent work shows that they can promote VEGF signaling in trans from the surface of an adjacent cell. This mode of signaling also alters the activation state and internalization of VEGF receptors.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Selleck SB

doi

10.1016/j.molcel.2006.05.004

subject

Has Abstract

pub_date

2006-05-19 00:00:00

pages

431-2

issue

4

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(06)00295-4

journal_volume

22

pub_type

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