Abstract:
:In this issue of Molecular Cell, Guo et al. (2014) report that misfolded or aggregated nuclear proteins, such as pathogenic polyQ proteins, are cleared by a SUMO-dependent quality control pathway, which involves the E3 SUMO ligase PML and the SUMO-targeted ubiquitin ligase RNF4.
journal_name
Mol Celljournal_title
Molecular cellauthors
Gärtner A,Muller Sdoi
10.1016/j.molcel.2014.06.022subject
Has Abstractpub_date
2014-07-03 00:00:00pages
1-3issue
1eissn
1097-2765issn
1097-4164pii
S1097-2765(14)00530-9journal_volume
55pub_type
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