Transcription and processing of human microRNA precursors.

Abstract:

:MicroRNAs have recently emerged as key posttranscriptional regulators of eukaryotic gene expression, yet our understanding of how microRNA expression is itself controlled has remained rudimentary. This review describes recent insights into the mechanisms governing microRNA transcription and processing in vertebrates and their implications for understanding the regulation of microRNA biogenesis.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Cullen BR

doi

10.1016/j.molcel.2004.12.002

subject

Has Abstract

pub_date

2004-12-22 00:00:00

pages

861-5

issue

6

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(04)00756-7

journal_volume

16

pub_type

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