Abstract：
PURPOSE/OBJECTIVES:To provide an overview of the evidence that supports a role for the proinflammatory cytokines interleukin-1beta (IL-1beta), tumor necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6) in the etiology of cancer chemotherapy-related symptoms. DATA SOURCES:Electronic nursing, psychology, and medicine databases; online meeting abstracts; and personal experimental observations. DATA SYNTHESIS:Substantial evidence implicates the proinflammatory cytokines IL-1beta, TNF-alpha, and IL-6 in the etiology of chemotherapy-related anorexia, cachexia, anemia, pain, sleep disturbance, fatigue, and depression. CONCLUSIONS:Further investigation into the role of these cytokines in the genesis of chemotherapy-related symptoms is warranted. The development of appropriate animal models likely will be key to understanding the relationship among cancer chemotherapy, proinflammatory cytokines, and symptoms. IMPLICATIONS FOR NURSING:Nurses traditionally have been leaders in symptom management. The symptoms experienced by patients undergoing chemotherapy have a profound negative impact on quality of life and patients' ability to receive prescribed treatments. An understanding of potential mechanisms underlying the physiologic and behavioral consequences of chemotherapy administration will aid nurses in the development of interventions to effectively manage chemotherapy-related symptoms.
journal_name
Oncol Nurs Forumjournal_title
Oncology nursing forumauthors
Wood LJ,Nail LM,Gilster A,Winters KA,Elsea CRdoi
10.1188/06.ONF.535-542subject
Has Abstractpub_date
2006-05-03 00:00:00pages
535-42issue
3eissn
0190-535Xissn
1538-0688journal_volume
33pub_type
杂志文章,评审abstract：PURPOSE/OBJECTIVES:To examine empirical research regarding the role of malglycemia (hyperglycemia, hypoglycemia, or glycemic variability) on clinical outcomes among hospitalized patients with cancer. DATA SOURCES:Research articles were obtained from the Ovid, PubMed, and CINAHL® databases. Key words used in the search...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：10.1188/12.ONF.458-465
更新日期：2012-09-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To determine whether patient navigation in a comprehensive community cancer center affects patient and staff perceptions of patient preparation for treatment, access to care, and overall satisfaction. DESIGN:Program evaluation with patient and staff surveys. SETTING:Comprehensive community cancer c...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/10.ONF.61-68
更新日期：2010-01-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To synthesize the literature regarding research on hope in adults with cancer. DATA SOURCES:CINAHL Plus® and PsycINFO databases. DATA SYNTHESIS:Sixteen articles published from 2005-2009 met the criteria for review. The literature was organized according to Oncology Nursing Society levels of evidenc...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：10.1188/11.ONF.E341-E350
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:To determine what women scheduled for colposcopy knew about the procedure and to understand their concerns about the test and its implications. DESIGN:Descriptive, exploratory, qualitative. SAMPLE AND SETTING:All women scheduled for colposcopy in a three-month period (n = 29) in an inner-city academic center ...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Adapting to a cancer diagnosis requires much time, energy, and effort. Patients, who often feel stressed and vulnerable, use several cognitive processes to help protect themselves and adapt to the illness. Denial, attributions, downward comparison, reappraisal of life, and developing a sense of mastery are some of the...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To review clinical applications and nursing care activities for patients receiving cladribine, a synthetic antineoplastic agent used to treat lymphoid malignancies. DATA SOURCES:Clinical trial data, published articles, reports from oncology nurses, and personal observations. DATA SYNTHESIS:Cladribi...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：
更新日期：1995-10-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To test the effects of an art-making class (AMC) on reducing anxiety and stress among family caregivers of patients with cancer. DESIGN:A pretest and post-test quasi-experimental design. SETTING:A residential care facility near tertiary treatment centers in the southeastern United States. SAMPLE:T...
journal_title：Oncology nursing forum
pub_type： 临床试验,杂志文章
doi：10.1188/07.ONF.E9-E16
更新日期：2007-01-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To describe women's representations of fatigue and fatigue-related coping efforts by women receiving chemotherapy. DESIGN:Descriptive, correlational. SETTING:Outpatient gynecologic oncology clinic. SAMPLE:Women receiving chemotherapy for gynecologic cancers. Fifty-four women were recruited; 49 (91...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/05.ONF.113-116
更新日期：2005-01-19 00:00:00
abstract：PURPOSE/OBJECTIVES:To identify and compare levels of distress and sources of problems among patients with breast cancer in early survivorship. DESIGN:Descriptive, cross-sectional. SETTING:A National Cancer Institute-designated comprehensive cancer center. SAMPLE:100 breast cancer survivors were selected to represent...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/15.ONF.E17-E23
更新日期：2015-01-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To evaluate the feasibility of a patient-controlled cognitive-behavioral intervention for pain, fatigue, and sleep disturbance during treatment for advanced cancer and to assess initial efficacy of the intervention. DESIGN:One group pre- and post-test design. SETTING:Outpatient oncology clinics at ...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/10.ONF.E151-E159
更新日期：2010-05-01 00:00:00
abstract：:Cognitive therapists believe that an individual's emotional reaction to a stressful situation is influenced by his or her perception of that situation. This article reports the findings of a cross-sectional survey comparing thought and image patterns in patients with cancer receiving first-time chemotherapy with patie...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1993-04-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To test body-related shame and guilt as predictors of breast cancer survivors' (BCS') moderate to vigorous intensity physical activity (MVPA) during six months and to examine motivational regulations as mediators of this association. . DESIGN:Prospective study. . SETTING:Survivors were recruited th...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/17.ONF.465-475
更新日期：2017-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To evaluate the permeability of chemotherapy gloves when using carmustine (BCNU), etoposide, and paclitaxel, which were selected based on their reported toxicity and unique solvent systems. SAMPLE:Thirteen brands of chemotherapy gloves and one brand of examination glove. Of the 14 glove types tested...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1999-10-01 00:00:00
abstract：OBJECTIVES:Guided by Mishel's uncertainty in illness theory, patterns of change in uncertainty were explored over time for patients with prostate cancer and their partners. In addition, the relationships between uncertainty and its antecedents were examined, and the role effects (patient versus partner) on these relati...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/20.ONF.721-731
更新日期：2020-11-01 00:00:00
abstract：:Little is known about how/why women who receive adjuvant chemotherapy treatment, hormone therapy, or radiation for nonmetastatic breast cancer gain weight. This study's purpose was to use the restraint-disinhibition model to understand susceptibility to weight gain, and the potential impact of exercise and dysphoria. ...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine the feasibility of using an emotional expression intervention with patients with cancer and test the hypothesis that emotional expression improves psychosocial adjustment. DESIGN:Sequentially randomized pretest/post-test design with repeated measures. SETTING:Two radiation therapy (RT) f...
journal_title：Oncology nursing forum
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1999-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To evaluate the relationship between nausea and exercise during and after adjuvant cancer treatment (chemotherapy and radiation therapy or chemotherapy alone). DESIGN:Secondary data analysis from a longitudinal, single-blinded, three-arm, randomized controlled trial. The trial failed to show a signi...
journal_title：Oncology nursing forum
pub_type： 杂志文章,随机对照试验
doi：10.1188/08.ONF.830-835
更新日期：2008-09-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To identify the symptom cluster of fatigue, weight gain, and altered sexuality caused by treatment for breast cancer. DATA SOURCES:Published research and literature review articles. DATA SYNTHESIS:Fatigue, weight gain, and altered sexuality commonly occur after breast cancer chemotherapy. Each symp...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：10.1188/04.ONF.1069-1075
更新日期：2004-11-16 00:00:00
abstract：PURPOSE/OBJECTIVES:To explore women's perspectives of the experience of surviving breast cancer. DESIGN:Descriptive, phenomenologic. SETTING:A community in the Southwestern United States. SAMPLE:Eight women, ages 34-70 (mean = 54.6 years), who had completed breast cancer therapy. Average time since completion of the...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
abstract：PURPOSE:To examine patients' with gynecologic cancer and supporters' reports of sharing and withholding cancer-related information during oncology visits, with a focus on navigating communication encounters more effectively. PARTICIPANTS & SETTING:18 women who were recently diagnosed with gynecologic cancer and th...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/19.ONF.676-685
更新日期：2019-11-01 00:00:00
abstract：:The Oncology Nursing Society (ONS) is committed to promoting excellence in oncology nursing and quality cancer care. In keeping with this mission, since 2001, ONS has prepared and disseminated a national Research Agenda. The ONS Research Agenda serves to identify gaps in the knowledge base needed to deliver quality ca...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/19.ONF.651-653
更新日期：2019-11-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To explore Korean American women's symbolic meanings related to their breasts and cervix, to examine attitudes and beliefs about breast and cervical cancer, and to find relationships between the participants' beliefs and their cancer screening behaviors. RESEARCH APPROACH:Descriptive, qualitative an...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/07.ONF.713-720
更新日期：2007-05-01 00:00:00
abstract：Objectives:To evaluate the association between heart failure and overall survival up to 10 years after breast cancer diagnosis. Sample & Setting:Women aged 65 years or older diagnosed with invasive breast cancer, with and without self-reported heart failure, were examined for this retrospective cohort study using Surv...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：2018-01-02 00:00:00
abstract：:Quality of life (QOL) was assessed in 10 patients receiving treatment with recombinant methionyl human granulocyte colony-stimulating factor (r-met-GCSF). The Ferrans & Powers Quality of Life Index (Cancer II) was administered at three different time points to patients with severe chronic neutropenia. Mean overall QOL...
journal_title：Oncology nursing forum
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1991-11-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To provide evidence-based research information about 31 herbs and natural products that have shown potential in early research to decrease cancer growth or as adjuncts with cancer treatment. DATA SOURCES:Names of herbs and natural products with potential to decrease cancer growth have been selected ...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：10.1188/04.ONF.E75-E90
更新日期：2004-07-13 00:00:00
abstract：OBJECTIVES:To examine the effect of burden of treatment and multimorbidity on the relationship between baseline characteristics and oral oncolytic agent (OOA) temporary stoppages. SAMPLE & SETTING:272 patients newly prescribed OOAs at six National Cancer Institute-designated comprehensive cancer centers. METHODS ...
journal_title：Oncology nursing forum
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1188/19.ONF.E135-E144
更新日期：2019-09-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To review current information on the types and components of risk assessment and associated considerations for clinical practice and education. DATA SOURCES:Published articles, book chapters, and clinical experience. DATA SYNTHESIS:Cancer risk assessment is a clinical process that is integral to ca...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：
更新日期：1998-10-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To review basic gene biology, discuss current genetic advances, and project the potential impact of these advances on oncology nursing practice. DATA SOURCES:Published professional articles, tests, proceedings, governmental and lay publications. DATA SYNTHESIS:The Human Genome Project seeks to bett...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：
更新日期：1995-03-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine sociocultural factors that influence an informed decision about colorectal cancer (CRC) screening among African American men and women. DESIGN:Descriptive, cross-sectional. SETTING:A medical center, a National Cancer Institute-designated comprehensive cancer center, and various social or...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/12.ONF.100-107
更新日期：2012-01-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To review the diseases of childhood for which bone marrow transplantation (BMT) is an accepted treatment modality. DATA SOURCES:Book chapters, journal articles. DATA SYNTHESIS:BMT is used to treat a wide variety of nonmalignant and malignant childhood conditions. Despite treatment successes, BMT an...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
