The impact of granulocyte colony-stimulating factor on quality of life in patients with severe chronic neutropenia.

Abstract:

:Quality of life (QOL) was assessed in 10 patients receiving treatment with recombinant methionyl human granulocyte colony-stimulating factor (r-met-GCSF). The Ferrans & Powers Quality of Life Index (Cancer II) was administered at three different time points to patients with severe chronic neutropenia. Mean overall QOL increased from time 1 to time 2 from a score of 23.72 to a score of 35.93 (p = 0.006). Overall QOL was maintained throughout the study with a mean score at time 3 of 36.96 (p = 0.002). Measures on all QOL subscales, including health and functioning and socioeconomic, improved significantly. Daily therapy with r-met-GCSF significantly improves the QOL of patients with severe chronic neutropenia.

journal_name

Oncol Nurs Forum

journal_title

Oncology nursing forum

authors

Fazio MT,Glaspy JA

subject

Has Abstract

pub_date

1991-11-01 00:00:00

pages

1411-4

issue

8

eissn

0190-535X

issn

1538-0688

journal_volume

18

pub_type

临床试验,杂志文章,随机对照试验
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    pub_type: 临床试验,杂志文章,随机对照试验

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