Abstract：
PURPOSE/OBJECTIVES:To review clinical applications and nursing care activities for patients receiving cladribine, a synthetic antineoplastic agent used to treat lymphoid malignancies. DATA SOURCES:Clinical trial data, published articles, reports from oncology nurses, and personal observations. DATA SYNTHESIS:Cladribine has shown response rates of nearly 90% in patients with hairy cell leukemia after a single, seven-day continuous infusion. Toxicities generally are mild, predictable, and rapidly reversible after therapy is discontinued. CONCLUSIONS:Currently, cladribine primarily is used in hairy cell leukemia therapy. Clinical trials of cladribine in treating other hematologic malignancies, primarily chronic lymphocytic leukemia and non-Hodgkin's lymphoma, have demonstrated encouraging results. IMPLICATIONS FOR NURSING PRACTICE:Nursing care for patients who receive cladribine involves management of side effects, which commonly include myelosuppression and fever, and monitoring of hemoglobin, platelet levels, and body temperature. Fever develops in most patients receiving cladribine but is usually transient and easily treated with acetaminophen. Infection as a cause of fever must be ruled out, especially in patients with neutropenia.
journal_name
Oncol Nurs Forumjournal_title
Oncology nursing forumauthors
Nelson MC,Hogan DKsubject
Has Abstractpub_date
1995-10-01 00:00:00pages
1395-400issue
9eissn
0190-535Xissn
1538-0688journal_volume
22pub_type
杂志文章,评审abstract：PURPOSE/OBJECTIVES:To assess patient and provider responses to a computerized symptom assessment system. DESIGN:Descriptive, longitudinal study with retrospective, longitudinal medical records review. SETTING:University-based National Cancer Institute-designated outpatient cancer center. SAMPLE:80 oncology outpatien...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/08/ONF.661-669
更新日期：2008-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine the differences among secular, traditional, and religious Israeli oncology nurses' intrinsic religiosity, extrinsic religiosity, spiritual well-being, and attitudes toward spiritual care. DESIGN:A comparative, descriptive study. SAMPLE:148 Israeli Jewish nurses drawn from the membership ...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/04.ONF.1179-1183
更新日期：2004-11-16 00:00:00
abstract：PURPOSE/OBJECTIVES:To describe the usefulness of daily pain management diaries to outpatients with cancer who participated in a randomized clinical trial of the PRO-SELF Pain Control Program. DESIGN:Randomized clinical trial in which a daily pain management diary was used for data collection in the control group and f...
journal_title：Oncology nursing forum
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1188/02.ONF.1304-1313
更新日期：2002-10-01 00:00:00
abstract：:Purpose/Objectives: To examine relationships between capacity to direct attention and the quality-of-life (QOL) domains of psychological and physical well-being in breast cancer survivors.Design: Descriptive, correlational.Setting: National Cancer Institute-designated oncology and county hospital outpatient clinics in...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/09.ONF.326-334
更新日期：2009-05-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine the lived experience of individuals when confronted with a life-threatening disease. RESEARCH APPROACH:Qualitative, phenomenologic using Giorgi's approach. SETTING:Patients' homes in the Midwest. PARTICIPANTS:Five women and two men, aged 44-74 years, who had a variety of diagnoses, incl...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/03.ONF.593-598
更新日期：2003-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To understand impediments to receiving and reporting timely follow-up care for abnormal Pap tests among Hispanic women. DESIGN:Descriptive, qualitative. SETTING:A federally funded cancer screening clinic in urban South Texas. SAMPLE:11 Mexican/Mexican-American women over 40 years old who appear in...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To review issues regarding the use of genetic materials and information. DATA SOURCES:Professional literature, regional and federal legislation. DATA SYNTHESIS:An analysis is provided of the relationship among advances in genetic technology, use of genetic material and information, and the developm...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：
更新日期：2000-04-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To test the feasibility of a multidisciplinary, multicomponent, theory-based decision aid. DESIGN:Prospective, one-group repeated measures. SETTING:Thoracic surgery clinic in a university hospital cancer center in central Virginia. SAMPLE:8 dyads, consisting of 16 total participants. METHODS:A mu...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/14.ONF.649-658
更新日期：2014-11-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine determinants of exercise during colorectal cancer treatment using the theory of planned behavior. DESIGN:A retrospective survey. SETTING:Cancer Registry of Alberta, Canada. SAMPLE:Randomly selected survivors of colorectal cancer (N = 110) diagnosed between 1992 and 1995 who had undergon...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To identify symptom clusters in older adult breast cancer survivors (ages 65-97 years) and examine whether symptom clusters are related to demographic, health, and quality-of-life variables. DESIGN:Factor analysis to identify possible symptom clusters. The resulting clusters then were correlated wit...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/11.ONF.672-680
更新日期：2011-11-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine maternal parenting during the time when a mother is diagnosed with and treated for breast cancer from the mothers' and adolescent daughters' perspectives. RESEARCH APPROACH:Empirical phenomenologic. SETTING:Sites in Indiana and Arizona. PARTICIPANTS:8 mothers and 1 of their adolescent d...
journal_title：Oncology nursing forum
pub_type： 杂志文章,多中心研究
doi：10.1188/08.ONF.113-120
更新日期：2008-01-01 00:00:00
abstract：:Although the right to health care is not written into the U.S. Constitution, moral and ethical tenets govern the delivery of optimal medical care universally and across the life continuum. Pertaining to children, in accordance with the Geneva Declaration of the Rights of the Child of 1924 and the United Nations Human ...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/16.ONF.281-283
更新日期：2016-05-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To describe social support from the perspective of Japanese women with breast cancer. DESIGN:Qualitative, descriptive, and interpretive. SETTING:Outpatient breast clinic at a cancer center in a metropolitan area in Japan. SAMPLE:Sixteen Japanese women diagnosed with stage I and II breast cancer wh...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：2000-10-01 00:00:00
abstract：:Therapy with interleukin-2 (IL-2) achieves reproducible objective responses in 20%-30% of patients with malignant melanoma (MM) and renal cell carcinoma (RCC). This cytokine has significant dose and schedule dependence with regard to both clinical toxicity and biological activity. This article reviews the current stat...
journal_title：Oncology nursing forum
pub_type： 临床试验,杂志文章,评审
doi：
更新日期：1989-11-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine the impact of advanced practice nurse (APN)-administered low-level laser therapy (LLLT) as both a stand-alone and complementary treatment for arm volume, symptoms, and quality of life (QOL) in women with breast cancer-related lymphedema. DESIGN:A three-group, pilot, randomized clinical tr...
journal_title：Oncology nursing forum
pub_type： 杂志文章,随机对照试验
doi：10.1188/13.ONF.383-393
更新日期：2013-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To review current information on the types and components of risk assessment and associated considerations for clinical practice and education. DATA SOURCES:Published articles, book chapters, and clinical experience. DATA SYNTHESIS:Cancer risk assessment is a clinical process that is integral to ca...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：
更新日期：1998-10-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine the currently available antiemetic medications and review their uses in the treatment of chemotherapy-induced nausea and vomiting (NV). DATA SOURCES:Published articles and book chapters. DATA SYNTHESIS:NV is a common yet potentially serious side effect of chemotherapy. Nurses must unders...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：10.1188/03.ONF.259-271
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVES:To explore the relationship between 16 symptom clusters (SCs), clinical and demographic influencing factors, and clinical outcomes over time in patients with pancreatic cancer (PC) undergoing surgical resection. SAMPLE & SETTING:143 patients with stage II PC undergoing surgical resection were recruited ...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/18.ONF.E53-E66
更新日期：2018-07-02 00:00:00
abstract：PURPOSE/OBJECTIVES:To investigate clinicians' experiences with supportive care screening and referral, and identify perceived barriers and benefits associated with implementation into the clinical setting. DESIGN:Qualitative, exploratory approach based on interviews. SETTING:A large regional hospital in Victoria, Aus...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/11.ONF.E204-E211
更新日期：2011-05-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To describe how a multidisciplinary task force on an oncology unit developed and implemented a program offering educational and emotional support for recently bereaved families. DATA SOURCES:Published books and articles and bereavement support models. DATA SYNTHESIS:Program components included bere...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To describe quality-of-life (QOL) concerns particular to women with ovarian cancer and to examine whether subgroups of patients with ovarian cancer have significantly different QOL concerns. DESIGN:Mailed survey. SAMPLE:Readership of an ovarian cancer newsletter. METHODS:A total of 1,383 surveys w...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/05.onf.1143-1149
更新日期：2005-11-03 00:00:00
abstract：PURPOSE/OBJECTIVES:To describe children's psychosocial adjustment to their mother's breast cancer and to compare their level of adjustment with normative data and with the level of adjustment of children of women with fibrocystic breast disease or diabetes. Hypotheses tested were (a) children of women with breast cance...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To update the state of the science on sleep-wake disturbances in adult patients with cancer, focusing on insomnia in the areas of prevalence, mechanisms and models, measurement, interventions, and implications for practice, health policy, education, and research. DATA SOURCES:Published articles, boo...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：10.1188/09.ONF.E165-E177
更新日期：2009-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To evaluate the quality of evidence on sleep-wake disturbances in people with cancer as a basis for clinical decision making and to discuss implications of the evidence for oncology clinicians, educators, and researchers. DATA SOURCES:Published, peer-reviewed articles. DATA SYNTHESIS:Members of the...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：10.1188/04.ONF.747-771
更新日期：2004-07-13 00:00:00
abstract：PURPOSE/OBJECTIVES:To identify and compare perceptions of RNs, registered dietitians (RDs), and patients regarding the best format and key nutrition information components that should be provided to patients during cancer treatment. DESIGN:Cross-sectional study using an opinion-based questionnaire. SETTING:Outpatient...
journal_title：Oncology nursing forum
pub_type： 杂志文章,多中心研究
doi：10.1188/04.ONF.989-996
更新日期：2004-09-17 00:00:00
abstract：PURPOSE/OBJECTIVES:To investigate the relationships among life stress, family functioning, family coping, reliance on formal and informal resources, and decisional conflict in cancer survivors. . DESIGN:Cross-sectional. . SETTING:Participants were recruited from the California Cancer Surveillance Program, hospital r...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/16.ONF.480-488
更新日期：2016-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To explore Korean American women's symbolic meanings related to their breasts and cervix, to examine attitudes and beliefs about breast and cervical cancer, and to find relationships between the participants' beliefs and their cancer screening behaviors. RESEARCH APPROACH:Descriptive, qualitative an...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/07.ONF.713-720
更新日期：2007-05-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To review basic gene biology, discuss current genetic advances, and project the potential impact of these advances on oncology nursing practice. DATA SOURCES:Published professional articles, tests, proceedings, governmental and lay publications. DATA SYNTHESIS:The Human Genome Project seeks to bett...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：
更新日期：1995-03-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To investigate knowledge, attitudes, and behaviors of nursing and midwifery students regarding breast self-examination (BSE). DESIGN:Descriptive, cross-sectional. SETTING:Aydin School of Health at Adnan Menderes University in Aydin, Turkey. SAMPLE:244 female students of nursing and midwifery. MET...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/09.ONF.E39-E46
更新日期：2009-01-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To determine whether a relationship exists between quality of life (QOL) and the sociodemographic characteristics of gender, age, marital status, educational level, occupation, and level of income in patients with cancer in Turkey. DESIGN:Exploratory study using a convenience sample. SETTING:Five h...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/06.ONF.1171-1176
更新日期：2006-11-27 00:00:00
