Corticotropin induced synthesis of the cholesterol desmolase enzymatic complex in cultured adrenal cortex cells.

abstract：:Pseudomonas aeruginosa is the most common cause of chronic and recurrent lung infections in patients with cystic fibrosis (CF) whose sputa contain copious quantities of P. aeruginosa toxin, pyocyanin. Pyocyanin triggers tissue damage mainly by its redox cycling and induction of reactive oxygen species (ROS). The react...

journal_title：Acta biochimica Polonica

authors： Cheluvappa R,Shimmon R,Dawson M,Hilmer SN,Le Couteur DG

更新日期：2008-01-01 00:00:00

abstract：:Ledakrin, 1-nitro-9-[3'-(N,N'-dimethyl)aminopropyl]aminoacridine administered intraperitoneally at a dose up to 20 mg/kg into sham operated and partially hepatectomized rats inhibited RNA polymerase B activity in the isolated liver nuclei. The average chain length of the in vitro transcript was reduced while the numbe...

journal_title：Acta biochimica Polonica

authors： Krawczyk Z

更新日期：1982-01-01 00:00:00

abstract：:Recently, embryo muscle development, which is crucial for postnatal skeletal muscle growth, has been investigated widely. Nutrients in ovo were suggested to be critical in embryo muscle development since the chick growth mostly relies on nutrients in eggs at the early developmental stage. Phytosterol esters (PE), whic...

journal_title：Acta biochimica Polonica

authors： Wang L,Zuo X,Zhao W,Zhou G,Luo L,Yang K,Shu G,Wang S,Gao P,Zhu X,Jiang Q,Wang L

更新日期：2020-03-19 00:00:00

abstract：:Exposure to environmental pollutants often leads to an upsurge in the production of reactive oxygen species (ROS). ROS oxidize cellular fatty acids to produce lipid peroxyl radicals, subsequently transformed into lipid peroxides, which decrease membrane fluidity and increase the activity of various enzymes implicated ...

journal_title：Acta biochimica Polonica

authors： Badmus JA,Odunola OA,Yekeen TA,Gbadegesin AM,Fatoki JO,Godo MO,Oyebanjo KS,Hiss DC

更新日期：2013-01-01 00:00:00

abstract：:The phosphatidylinositol-3-kinases (PtdIns-3-kinase) are a family of enzymes involved in the control of cell replication. One member of the family, the mammalian p110/p85 PtdIns-3-kinase, is a potential target for anticancer drug development because of its role as a component of growth factor and oncogene activated si...

journal_title：Acta biochimica Polonica

authors： Powis G,Berggren M,Gallegos A,Frew T,Hill S,Kozikowski A,Bonjouklian R,Zalkow L,Abraham R,Ashendel C

更新日期：1995-01-01 00:00:00

abstract：:Eight polymorphic restriction enzyme sites at phenylalanine hydroxylase locus from the parental chromosomes in Polish families with phenylketonuria were analyzed. Among 28 chromosomes studied, we identified haplotypes found within the Danish population. Haplotype 2 has been found in 25% of affected alleles. One of the...

journal_title：Acta biochimica Polonica

authors： Jaruzelska J,Borski K,Riess O,Blin N,Słomski R

更新日期：1989-01-01 00:00:00

abstract：:Trans-diamminedichloroplatinum(II) (trans-DDP) forms with DNA at 37 degrees C, more numerous interstrand cross-links than cis-DDP in the isolated DNA and DNA in the chromatin complex. An increase in the temperature to 42.5 degrees C had no effect on the interstrand cross-links of DND-Pt-DNA formed by the two isomers, ...

journal_title：Acta biochimica Polonica

authors： Kulamowicz I,Walter Z,Krupa R

更新日期：1990-01-01 00:00:00

abstract：:The relationships between bone turnover, the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and vitamin D are complex, but still not fully explained. The GH/IGF-1 axis and vitamin D can mutually modulate each other's metabolism and influence the activation of cell proliferation, maturation, and mineraliza...

journal_title：Acta biochimica Polonica

authors： Witkowska-Sędek E,Stelmaszczyk-Emmel A,Majcher A,Demkow U,Pyrżak B

更新日期：2018-01-01 00:00:00

abstract：:The proteolytic activity of three Pseudomonas aeruginosa strains, ATCC 27853 - a reference strain, and two clinical isolates was tested. The activity was examined after culturing the bacteria in two different growth media: the minimal M9 medium and rich Luria-Bertani broth (LB). Based on zymograms and protease activit...

journal_title：Acta biochimica Polonica

authors： Andrejko M,Zdybicka-Barabas A,Janczarek M,Cytryńska M

更新日期：2013-01-01 00:00:00

abstract：:Sulfate uptake, the first step of sulfate assimilation in all organisms, is a highly endoergic, ATP requiring process. It is under tight control at the transcriptional level and is additionally modulated by posttranslational modifications, which are not yet fully characterized. Sulfate anion is taken up into the cell ...

journal_title：Acta biochimica Polonica

authors： Piłsyk S,Paszewski A

更新日期：2009-01-01 00:00:00

abstract：:This brief resume enumerates the multiple actions of melatonin as an antioxidant. This indoleamine is produced in the vertebrate pineal gland, the retina and possibly some other organs. Additionally, however, it is found in invertebrates, bacteria, unicellular organisms as well as in plants, all of which do not have a...

journal_title：Acta biochimica Polonica

authors： Reiter RJ,Tan DX,Mayo JC,Sainz RM,Leon J,Czarnocki Z

更新日期：2003-01-01 00:00:00

abstract：:In recent decades a significant raise in the incidence of myocardial infarction among young women has been recorded. It is presumed that, apart from the classical risk factors, other reasons exist for premature atherosclerosis in young women, related to the homeostasis of gonadal hormones. The aim of the study was to ...

journal_title：Acta biochimica Polonica

authors： Ablewska U,Jankowski K,Rzewuska E,Liszewska-Pfejfer D,Hryniewiecki T

更新日期：2011-01-01 00:00:00

abstract：:The early molecular events of glucocorticoid-induced apoptosis have been investigated by studying glucocorticoid receptor levels, as well as binding activities to GRE and AP-1 sequences, using nuclear extracts from dexamethasone (Dex)-treated rat thymocytes. When the time-course of glucocorticoid-receptor complexes in...

journal_title：Acta biochimica Polonica

authors： Sikora E,Rossini GP,Grassilli E,Bellesia E,Salomoni P,Franceschi C

更新日期：1996-01-01 00:00:00

abstract：:Fluorescent tri-cyclic purine analogs, derivatives of isoguanine and adenine, were examined as potential substrates of purine-nucleoside phosphorylase. It was found previously that etheno- derivatives of both compounds are ribosylated in phosphate-free media, but ribosylation places in some instances differ from purin...

journal_title：Acta biochimica Polonica

authors： Stachelska-Wierzchowska A,Wierzchowski J

更新日期：2019-12-05 00:00:00

abstract：:Cardiac fibrosis is referred to as an excessive accumulation of stromal cells and extracellular matrix proteins in the myocardium. Progressive fibrosis causes stiffening of the cardiac tissue and affects conduction of electrical impulses, leading to heart failures in a broad range of cardiac conditions. At the cellula...

journal_title：Acta biochimica Polonica

authors： Działo E,Tkacz K,Błyszczuk P

更新日期：2018-01-01 00:00:00

abstract：:Fucoxanthin, diadinoxanthin and diatoxanthin are carotenoids found in brown algae and most other heterokonts. These pigments are involved in photosynthetic and photoprotective reactions, and they have many potential health benefits. They can be extracted from diatom Phaeodactylum tricornutum by sonication, extraction ...

journal_title：Acta biochimica Polonica

authors： Tokarek W,Listwan S,Pagacz J,Leśniak P,Latowski D

更新日期：2016-01-01 00:00:00

abstract：:Bacteriophage lambda is not able to lysogenise the Escherichia coli rpoA341 mutant. This mutation causes a single amino acid substitution Lys271Glu in the C-terminal domain of the RNA polymerase alpha subunit (alphaCTD). Our previous studies indicated that the impaired lysogenisation of the rpoA341 host is due to a de...

journal_title：Acta biochimica Polonica

authors： Gabig M,Obuchowski M,Ciesielska A,Latała B,Wegrzyn A,Thomas MS,Wegrzyn G

更新日期：1998-01-01 00:00:00

abstract：:A cytosolic acetyl-CoA hydrolase (CACH) cDNA has been isolated from mouse liver cDNA library and sequenced. Recombinant expression of the cDNA in insect cells resulted in overproduction of active acetyl-CoA hydrolyzing enzyme protein. The mouse CACH cDNA encoded a 556-amino-acid sequence that was 93.5% identical to ra...

journal_title：Acta biochimica Polonica

authors： Suematsu N,Okamoto K,Isohashi F

更新日期：2002-01-01 00:00:00

abstract：:This is a short survey of the adaptive mutation processes that arise in non- or slowly-dividing bacterial cells and includes: (i) bacterial models in which adaptive mutations are studied; (ii) the mutagenic lesions from which these mutations derive; (iii) the influence of DNA repair processes on the spectrum of adapti...

journal_title：Acta biochimica Polonica

authors： Janion C

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Tunneled catheters are becoming increasingly used as a permanent dialysis access. Easy way of insertion and good long-term patency make them competitive to fistulas in some groups of patients. METHODS:Late complications and survival of 180 tunneled catheters inserted from June 2010 to December 2013 in 171 u...

journal_title：Acta biochimica Polonica

authors： Weber E,Liberek T,Wołyniec W,Gruszecki M,Rutkowski B

更新日期：2016-01-01 00:00:00

abstract：:A new enzymatic activity, which catalyses formation in vitro of di-O-(indole-3-acetyl)-D-glucose from 1-O-(indole-3-acetyl)-beta-D-glucose has been found in extracts of Zea mays seedlings. The structure of di-O-(indole-3-acetyl)-D-glucose, not as yet described, has been assigned by GC-MS, 1H NMR and ammonolysis. ...

journal_title：Acta biochimica Polonica

authors： Szmidt-Jaworska A,Kesy J,Kopcewicz J

更新日期：1997-01-01 00:00:00

abstract：:An analysis has been made, with the aid of 1H NMR spectroscopy, of the solution conformation of the known antimetabolite, 9-beta-D-xylofuranosyladenine (xyloA), and of its 8-bromo analogue. For xyloA, the results point to a strong preference for the sugar ring of the conformation type N (C(3') endo), a relatively low ...

journal_title：Acta biochimica Polonica

authors： Ekiel I,Shugar D

更新日期：1979-01-01 00:00:00

abstract：:Advanced oxidation protein products (AOPPs) are protein markers of oxidative stress with pro-inflammatory properties that accumulated in liver cirrhosis. In the present study, we investigated the association between chronic inflammatory response triggered by AOPPs and the severity of liver disease as assessed by the C...

journal_title：Acta biochimica Polonica

authors： Zuwała-Jagiełło J,Pazgan-Simon M,Simon K,Warwas M

更新日期：2011-01-01 00:00:00

abstract：:Betapapillomaviruses have been linked to the development of nonmelanoma skin cancers. A great diversity of these viruses in skin specimens requires the use of sensitive and reliable detection methods. There are currently no standardized assays for diagnostic purposes. A combination of several molecular methods has gre...

journal_title：Acta biochimica Polonica

authors： Kopeć J,Szostek S,Sułowicz J,Zawilińska B

更新日期：2020-06-08 00:00:00

abstract：:Kainate is a glutamate analog that produces neuronal excitation resulting in seizures within hours following its intraperitoneal injection into adult rats. Then, at 2-3 days after the treatment, neurodegeneration of apoptotic character can be observed in limbic system. As a consequence, plastic reorganization and glia...

journal_title：Acta biochimica Polonica

authors： Kaminska B,Filipkowski RK,Biedermann IW,Konopka D,Nowicka D,Hetman M,Dabrowski M,Gorecki DC,Lukasiuk K,Szklarczyk AW,Kaczmarek L

更新日期：1997-01-01 00:00:00

abstract：:Interaction of copper(II) with guanosine, 2'-deoxyguanosine, 1-methylguanosine, 7-methylguanosine and GMP was studied withe use of spectroscopic and magneto-chemical methods. The main site of copper(II) binding in guanosine is nitrogen N-7; participation of N-1 is not excluded. The involvement of carbonyl oxygen in co...

journal_title：Acta biochimica Polonica

authors： Maskos K

更新日期：1978-01-01 00:00:00

abstract：:Murine leukemia L1210 cells contain active glucosamine 6-phosphate synthase inhibited by N3-4-methoxyfumaroyl-L-2,3-diaminopropanoic acid (FMDP). However, FMDP-peptides do not exhibit any cytotoxicity against these cells, HeLa S3 human cervical carcinoma cells, and LL2 murine Lewis lung carcinoma cells. It is suggeste...

journal_title：Acta biochimica Polonica

authors： Bontemps-Gracz M,Milewski S,Borowski E

更新日期：1991-01-01 00:00:00

abstract：:Patients with colorectal carcinoma showed statistically significant lower values of transferrin saturation, total iron binding capacity and serum iron level as compared with control group, while the level of ferritin and the size of labile iron pool in carcinoma patients were higher, although this difference was not s...

journal_title：Acta biochimica Polonica

authors： Gackowski D,Kruszewsk M,Banaszkiewicz Z,Jawien A,Olinski R

更新日期：2002-01-01 00:00:00

abstract：:Public and private EST (Expressed Sequence Tag) programs provide access to a large number of ESTs from a number of plant species, including Arabidopsis, corn, soybean, rice, wheat. In addition to the homology of each EST to genes in GenBank, information about homology to all other ESTs in the data base can be obtained...

journal_title：Acta biochimica Polonica

authors： Rafalski JA,Hanafey M,Miao GH,Ching A,Lee JM,Dolan M,Tingey S

更新日期：1998-01-01 00:00:00

abstract：:DNA methylation and histone modifications are major components of cellular epigenetic pattern determining gene expression. Cancer cells have their own epigenetic array, which can be different in cells of primary and metastatic tumors. In the present work we investigated effects of 1 mM valproic acid (VPA), a histone d...

journal_title：Acta biochimica Polonica

authors： Ghecham A,Senator A,Pawlowska E,Bouafia W,Błasiak J

更新日期：2019-07-09 00:00:00