Abstract：
:Recently, the role of small heat shock proteins (HSPs) has been widely recognized in cancer research. Small HSPs are tumorprotective via numerous, independent mechanisms such as: oxidative stress, protection preventing protein denaturation, anti-apoptotic activity, and likely direct suppression of the immune system. However, it is unclear whether they play any role in the initial steps in carcinogenesis. This article seeks to familiarize the reader with general characteristics of small HSPs (especially HSP-27, alphaA/B-crystallins), their tissue distribution with special regard on expression in malignant specimens, and biological properties of intracellular HSP-27 and alphaA/B-crystallins promoting tumor genesis and growth. A separate chapter describes immunomodulatory characteristics of extracellular HSP-27 with special emphasis on their plausible effect on the neoplasm development.
journal_name
Arch Immunol Ther Exp (Warsz)journal_title
Archivum immunologiae et therapiae experimentalisauthors
Laudanski K,Wyczechowska Ddoi
10.1007/s00005-006-0013-3subject
Has Abstractpub_date
2006-03-01 00:00:00pages
103-11issue
2eissn
0004-069Xissn
1661-4917journal_volume
54pub_type
杂志文章,评审abstract：:The results of treatment with intrauterine transfusion are presented. The analysis comprised 48 successful transfusions into 29 foetuses. The reference group consisted of 11 transfusions which proved nonfeasible or ineffective and 54 untreated cases. Following blood treatment, the newborn mortality rate dropped more t...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:alpha-Carboline derivatives substituted with methyl groups at C-2, C-4, C-2,4, C-6 and C-8 position were subjected to N-1 methylation performed by Kitasatosporia setae. The yield of formed corresponding alpha-iso-carbolines varied, depending on the position of methyl substituent. It has been observed that the methyl g...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:The role of Epstein-Barr virus (EBV) in the biology and clinical characteristics of diffuse large B cell lymphoma (DLBCL) is still poorly defined. A new provisional entity EBV-positive DLBCL of the elderly has been described in Asian population. Its incidence and prognosis remains unknown in middle European patients. ...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：10.1007/s00005-015-0341-2
更新日期：2016-04-01 00:00:00
abstract：INTRODUCTION:The objective of the study was to assess the relationship between Chlamydia trachomatis (C.t.) infection of the prostate and the concentration of citric acid. MATERIALS AND METHODS:The study involved 60 patients with chronic prostatitis (NIH III). Urethral swabs and expressed prostatic secretions (EPS) we...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：10.1007/s00005-006-0009-z
更新日期：2006-01-01 00:00:00
abstract：:Many features of the interferon gamma (IFN-gamma) signaling pathway would suggest that it is anti-tumorigenic. The IFN-gamma signaling pathway leads to apoptosis and to the expression of immune function proteins that could cooperate with T cells in the destruction of tumor. Various lines of experimental approach have,...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章,评审
doi：
更新日期：2002-01-01 00:00:00
abstract：:Patients with end stage renal disease (ESRD) suffer from many disturbances of the immune system. These immunopathologies are related to the higher failure of vaccination, and increased prevalence of infections and neoplasms. In the presented article, we review the current data regarding the role of monocytes in immune...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章,评审
doi：10.1007/s00005-012-0191-0
更新日期：2012-12-01 00:00:00
abstract：:Distribution of esterase D types was studied in a sample of the Polish population numbering 885 subjects. Frequency of EsDl-1 type was 0.810, EsD2-1 -- 0.174, and EsD2-2 -- 0.16. Frequency of the genes EsD1 and EsD2, which determine this system, were 0.897 and 0.103 respectively. A study of 613 mother-child pairs reve...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:2538 strains of Shigella sonnei bacilli, isolated from patients in the years 1959-1972, have been tested for drug-resistance. The strains examined came from different regions of Poland. Drug-resistance has been determined by the method of "multi-arm" disks of filter-paper. In investigations 12 chemotherapeutics have b...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Human interferon alpha (HuIFN-alpha) preparations induced in human peripheral white blood cells by Sendai virus were analyzed for activity after ultrafiltration, ion exchange, metal ion chromatography and isoelectrofocusing. It was found that HuIFN-alpha forms complexes with various physical properties and activities....
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Peripheral blood T lymphocytes and T cell subsets were analyzed in 19 patients with chronic active hepatitis B virus infection. The T cell subpopulations were defined by indirect immuno-fluorescence using monoclonal antibodies, and additionally, natural killer cell activity against K 562 human erythroleukemic cell has...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The idea that vaccination can be used to fight cancer is not new. Approximately 100 years ago, researchers attempted to stimulate a tumor-specific, therapeutic immune response to tumors by injecting patients with cells and extracts from their own tumors, or tumors of the same type from different individuals. During th...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章,评审
doi：10.1007/s00005-011-0129-y
更新日期：2011-08-01 00:00:00
abstract：:Studies on the propagation dynamics of Aujeszky's disease virus and the formation of general and local joint immunity were to provide information explaining the mechanism of experimental rheumatoid arthritis in animals. It was shown that: Aujeszky's disease virus administered intramuscularly caused viremy on 3-4th day...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:The objective of our study was to evaluate the impact of sex and age on the prevalence of sensitization to inhalant allergens. The study was performed as a part of Polish Epidemiology of Allergic Diseases study, and data concerning citizens of Wroclaw were analyzed. The participants were divided into three age groups ...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：10.1007/s00005-016-0425-7
更新日期：2017-06-01 00:00:00
abstract：:Using the serial dilution method in solid media, sensitivity of isolated strains of S. aureus and E. coli to phosphonomycin, streptomycin, penicillin G and ampicillin, and the effect of combined action of phosphonomycin with these antibiotics were studied. Against S. aureus strains, phosphonomycin in combination with ...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:In the report new contact allergens and allergen sources detected in Warsaw in the period 1975-1977 are described. They are divided into 3 groups: industrial allergens, remaining occupational allergens and cosmetics. There are given some data concerning the substances present in industrial oils, hardeners and epoxy re...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:Rabbits infected intradermally with T. pallidum at four sites on the clipped back were treated with cyclophosphamide, 1 mg/kg body weight, twice before and every two days after inoculation for five months, or 5-fluorouracil 2.5 mg/kg body weight, according to the same regimen. Humoral response, as measured repeatedly ...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:CEA and NCA show an increased mobility in SDS-polyacrylamide gel electrophoresis if the samples are preheated in 1% SDS for 5 min at 100 degrees C. Now we found that the slow-to-fast form conversion of CEA and NCA also occurs under milder conditions and is reversible at low SDS concentration. At 100 degrees C the conv...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The influence of antibiotics and purine and pyrimidine analogues on cells forming rosettes EA and EAC was evaluated in vitro. At the same time pH of solutions of examined immunosuppressors was estimated and a series of experiments with a buffer of appropriate pH was carried out. It was estimated that the effect inhibi...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:The incidence of cutaneous malignant melanoma, tumors arising from melanocytes, has increased markedly over the past few years in many countries. Although early melanoma is curable through surgical excision, the prognosis of advanced melanoma is very poor, this tumor being resistant to current therapies. Thus there is...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章,评审
doi：10.1007/s00005-007-0043-5
更新日期：2007-11-01 00:00:00
abstract：:The studies concerned in vitro migration of peripheral blood lymphocytes of rabbits given intravenously one dose of E. coli lipopolysaccharide (LPS) and antipyretic doses of acetylsalicylic acid (ASA), indomethacin (IND) or mefenamic acid (MEFA). In normothermic animals, ASA appeared to inhibit in vitro the spontaneou...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Pharmacological activity of 6 newly synthetized water-soluble derivatives of barbiturylo propanosulfonic acids, was evaluated. The compounds were obtained under the conditions of the Ritter reaction. The experiments were performed with the aim to determine the anti-inflammatory and immunotropic activities as well as t...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Juvenile idiopathic arthritis (JIA) is the most common cause of chronic arthritis in childhood. Up to 50% of patients are resistant to standard therapy, which includes non-steroid anti-inflammatory drugs, corticosteroids, disease-modifying anti-rheumatic drugs and biologic therapies. Intra-articular injection of mesen...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章,评审
doi：10.1007/s00005-017-0493-3
更新日期：2018-08-01 00:00:00
abstract：:The progress in melanoma immunotherapy highlights the importance of immunotherapy for cancer treatment. Although the concept of immunotherapy emerged in the beginning of the twentieth century, the end of the century signaled the start of modern immunotherapy, which has recently allowed a staggering progress in the fie...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章,评审
doi：10.1007/s00005-017-0491-5
更新日期：2018-04-01 00:00:00
abstract：:It was demonstrated that exogenous GH suppressed the resistance to L. monocytogenes infection in Listeria resistant C57Bl/6 and susceptible A/J mice. However, different parameters of the immunological reaction to Listeria were affected by GH treatment in these mouse strains. In C57Bl/6 mice GH decreased accumulation o...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:In order to optimize the regimen of pathogenetic therapy of glomerulonephritis with nephrotic syndrome we used transfusions of plasma containing specific anti-HLA antibodies against the patient's phenotype as a part of the treatment in the acute stages of disease. The method was theoretically based on the conception o...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:After more than two decades of investigation, the biological role of the gammadelta T-cell receptors (TCRs) remains elusive. In fact, a theory of ligand recognition is still lacking that accounts for their adaptable structure, their peripheral selection, and the observed responses of gammadelta T cells, which do not r...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章,评审
doi：10.1007/s00005-009-0017-x
更新日期：2009-03-01 00:00:00
abstract：:Concentrations of immunoglobulins IgG, IgM, IgA, E-, EAC-rosette forming lymphocyte counts and phagocytic function of granulocytes to Staphylococcus aureus were studied during the long-term polychemotherapy in 19 children with NHL and in the control group consisting of 15 healthy children. The decrease in levels of Ig...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：:Expression of Fc gamma and Fc mu receptors on human peripheral blood T lymphocytes of two subsets with high (E early rosette forming presumably in vivo activated cells, TEe) and low affinity of E receptors (E late rosette forming presumable resting cells, TEl) was investigated. Different distribution pattern of T gamm...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The purpose of this study is to evaluate the relationship between the concentration of interleukin-8 (IL-8) in exhaled breath condensate (EBC) and bronchoalveolar lavage fluid (BALF) with the disease activity score and pulmonary function of systemic lupus erythematosus (SLE) patients with and without pulmonary fibrosi...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：10.1007/s00005-014-0270-5
更新日期：2014-06-01 00:00:00
abstract：:Fourteen patients with chronic renal failure and their prospective living donors were examined. DNA uptake by donors' monocultures, recipients' monocultures and mixed cultures was measured. The influence of X-ray treated cells on proliferative capacity of untreated cells in these three types of cultures was studied. T...
journal_title：Archivum immunologiae et therapiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
