Abstract:
:Studies on the propagation dynamics of Aujeszky's disease virus and the formation of general and local joint immunity were to provide information explaining the mechanism of experimental rheumatoid arthritis in animals. It was shown that: Aujeszky's disease virus administered intramuscularly caused viremy on 3-4th day after its application and disappeared from the blood circulation on 5-6th day, introduced into the pig ankle joint, the virus was eliminated from the articular fluid two hours after injection, but it appeared again 3-7 days later probably due to the propagation in the cells of the synovial membrane, and that first parenteral administration of the virus induced the formation of neutralizing antibodies in low titer (5-10 units); application of the virus for the second time brought about a considerable increase of antibodies titer within 40-80 units.
journal_name
Arch Immunol Ther Exp (Warsz)journal_title
Archivum immunologiae et therapiae experimentalisauthors
Wawrzkiewicz J,Majer-Dziedzic B,Lipińska M,Silmanowicz Psubject
Has Abstractpub_date
1978-01-01 00:00:00pages
807-12issue
1-6eissn
0004-069Xissn
1661-4917journal_volume
26pub_type
杂志文章abstract::Identification of cells producing ATL was carried out on suspensions of cells enriched with lymphocytes T, B and macrophages. The cells were isolated from the spleen of syphilitic rabbits and from their testes when the rabbits were infected intratesticularly. The isolation of lymphocytes and macrophages was performed ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::In this work the biocompatibility of porous bioceramic implanted to the rabbit femoral bone was studied. The animals were killed 3, 6, 9, 14, 18 and 30 days after implantation and the callus with surrounding periosteum from the site of implant was taken for the studies. Morphological investigations of the callus were ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::Spotted souslik's interferon beta (So IFN beta), bovine interferon beta (Bov IFN beta) and mouse IFN beta/a were purified on Controlled Pore Glass (CPG) using original CPG, not modified, and CPG with boron enriched surface. The surface boron atoms enrichment of CPG lead to higher selectivity of interferon binding and ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::In rheumatoid arthritis (RA), T cells infiltrate into the synovial membrane where they initiate and maintain activation of macrophages and synovial fibroblasts, transforming them into tissue-destructive effector cells. The diversity of the disease process and the formation of complex lymphoid microstructures indicate ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
abstract::The paper presents the evaluation of interleukin 6 (IL-6) and interleukin 6 soluble receptor (sIL-6R) values in the blood serum of patients with various forms of periodontitis (P), as confronted with local state. The study involved a group of 15 patients with P, including 4 patients with rapidly progressive periodonti...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::A mouse monoclonal IgA antibody (A008), anti-blood group A antigen, was shown to dissociate into heavy (H) and light (L) polypeptide chains under non-reducing conditions. The dissociation occurred in the presence of 0.2% sodium dodecyl sulphate (2 h at room temperature) or at elevated temperature (1 h at 70 degrees C)...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::After several decades of research into the macrophage migration inhibitory factor (MIF), its diverse actions in the immune system are yet to be fully revealed. What has become clear is that MIF plays an important role in both innate and adaptive immunity. However, while several pathways mediating the function of MIF i...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:2004-11-01 00:00:00
abstract::Impairment of interferon (IFN) system in human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) became a basis for searching IFN responses to monitor the disease progression. For detailed investigations 16 HIV+/AIDS patients with at least 4 successively taken blood samples available...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The comparison of electrophoretic protein patterns and concentrations of the G, A and M immunoglobulins before initiation of oral IFN-alpha therapy of viral hepatitis and after 2 weeks of treatment allow to predict patient's response. Patient who after 2 weeks of treatment with ultra-low orally administered IFN-alpha ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Signal transducer and activator of transcription (STAT) is a family of transcription factors composed of seven members. Gene-targeted mice of each STAT family protein displayed defective responses to cytokines, demonstrating an important role in cytokine-mediated biological responses. However, unlike the mice lacking ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:2001-01-01 00:00:00
abstract::Vascular endothelial growth factor-A (VEGF) is a key regulator of physiological hemangiogenesis during development, postnatal growth, and homeostasis. It is well known that VEGF is required for effective coupling of angiogenesis to endochondral and membranous bone formation during skeletal development. However, less w...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:10.1007/s00005-014-0285-y
更新日期:2014-10-01 00:00:00
abstract::Clinical trials have shown that the type I interferon (IFN)-alpha/beta have some beneficial effects on organ-specific autoimmune diseases, such as Behcet's diseases and multiple sclerosis, although the precise mechanisms remain largely unresolved. T helper cells 1 (Th1)-mediated autoimmune responses are involved in th...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract:INTRODUCTION:The aim was to evaluate the ability of egg yolk antibody (IgY) in blocking Staphylococcus aureus growth in vitro. MATERIALS AND METHODS:Specific IgY was produced by immunizing hens with formalin-killed S. aureus (ATCC 33593). Specific IgY against S. aureus was obtained from the yolks of their eggs with a ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:10.1007/s00005-009-0041-x
更新日期:2009-09-01 00:00:00
abstract::Haemolytic activity of complement (CH50) and occurrence of circulating immune, complexes (CIC) were studied in serum samples from children with mumps meningitis taken at regular intervals. The decrease of CH50 was observed in 46 out of 77 samples (60%) in the Ist examination, between 1-6th day from the appearance of s...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common disease that has a considerable impact on the quality of life. Alterations in signalling pathways may contribute to the ongoing inflammation and proliferation in CRSwNP. The MEK1/2-ERK1/2 pathway transmits signals from many extracellular molecules to regula...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:10.1007/s00005-014-0281-2
更新日期:2014-06-01 00:00:00
abstract::Umbilical cord blood transplantation (UCBT) is known to be associated with increased risk of infections, compared to bone marrow or peripheral blood stem cell transplantation. In viral diseases for which specific treatment is available, real-time PCR assays are reliable diagnostic tools for timely initiation of approp...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:10.1007/s00005-010-0096-8
更新日期:2010-12-01 00:00:00
abstract::Several new amides and anilides of alpha-aziridinyl-beta-/p-chlorobenzoyl/-propionic acid were synthetized. The beta-/p-chlorobenzoyl/-acrylic acid 2 was used as the substrate. This compound was converted by reaction with appropriate amine into amides and anilides of beta-/p-chlorobenzoyl/-acrylic acid (3-10). These c...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::The influence of chronic antigenic stimulation, immunosuppression with azathioprine, or both acting simultaneously on the lymphoreticular system in Swiss mice was studied. The response consisted of abnormal hyperplasia of the lymphoreticular system with the character of malignant lymphoma. On the basis of the microsco...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::New treatment strategies for HIV/AIDS are very successful in reducing viral load. However, reconstitution of the immune system takes about one year and may be insufficient or remain incomplete. During this time the patient remains prone to opportunistic infections as a result of the complex immune dysfunction caused b...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract::Five tuftsin analogues, containing one or two of the basic amino acid residues, respectively in position: 2, 3, 2 and 4, 2 and 3--of the peptide chain, were synthesized and tested for biologic activity by the Najjar test. ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::Stimulatory effect of immunomodulators on cellular proliferation was studied on the experimental model of regenerating rat liver. Thymus factor (TFX), isoprinosine and, to a lesser degree, levamisole, were observed to accelerate and enhance a compensative hypertrophy of the remaining lobes of liver. This phenomenon co...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::In patients with endogenous depression in remission, decline of systolic blood pressure and a statistically significant shortening of pulse time were found. ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::It has been stated that experimental infection with 0.01 LD50 Pseudomonas aeruginosa 74 decreases the phagocytic activity of mouse neutrophiles and peritoneal macrophages in relation to latex particles. In the course of infection suppression of phagocytic activity of peritoneal macrophages was delayed for two days as ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Two major classes of lipids participating in signaling cascades in immune cells are known today. One comprises glycerol-based lipids with diacylglycerol as its most prominent member that mediates the activation of classical and novel protein kinase C molecules. The second group contains the sphingolipids, with the bes...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
abstract::Pharmacological activity of 6 newly synthetized water-soluble derivatives of barbiturylo propanosulfonic acids, was evaluated. The compounds were obtained under the conditions of the Ritter reaction. The experiments were performed with the aim to determine the anti-inflammatory and immunotropic activities as well as t...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Crude burn toxin was obtained from human skin scalded for 1 min at 90 degrees C in vitro. The toxin solubilized with 8 M urea was administered to rabbits to obtain antiserum. The antigenic analysis carried out by immunodiffusion and immunoelectrophoresis demonstrated that urea-extractable toxin solution differed from ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Fresh porcine blood platelets, subjected to ethanol acid extraction and purification on DEAE-Sephadex A-50 and CM-Sephadex C-50, were used to obtain partially purified, cationic PDGF (pI 8.5-10) of Mr 38,000 and biological activity 10(4) U/ml. Reduction of porcine PDGF with 2-mercaptoethanol revealed the presence of t...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::By employing the rosette technique the peripheral T and B lymphocytes were determined in 24 patients with terminal renal failure treated by diet and 17 subjects treated by program of repeated hemodialysis. The decreased percentage of B-cells was found in both groups of patients in comparison with the control group. Th...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::Outer membrane proteins (OMP) isolated from Shigella flexneri, Escherichia coli, Proteus vulgaris and Salmonella typhimurium were tested for their protective activity. Each OMP preparate given to mice intraperitoneally in a single injection (5 micrograms/per mouse) protected the animals not only in homologous but also...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::A modified nitrobluetetrazolium test (NBT) was used to study 114 blood samples from calves, beginning from the birth to the 21-st day of life. The calves came from two farms with different breeding conditions. The absolute number of granulocytes with the ability to reduce NBT ranged between 0-9737. Comparison of mean ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00