Studies on the human mixed lymphocyte culture. I. The influence of the irradiated autogenic and allogenic lymphocytes on DNA synthesis.

Abstract:

:Fourteen patients with chronic renal failure and their prospective living donors were examined. DNA uptake by donors' monocultures, recipients' monocultures and mixed cultures was measured. The influence of X-ray treated cells on proliferative capacity of untreated cells in these three types of cultures was studied. The suppressing effect of irradiated cells was found in 52%, the enhancing one in 7% and no effect was observed in 41% of lymphocyte cultures. The possible explanations of the findings are discussed.

authors

Wojtulewicz-Kurkus J,Skopińska E,Nowaczyk M

subject

Has Abstract

pub_date

1978-01-01 00:00:00

pages

1001-3

issue

1-6

eissn

0004-069X

issn

1661-4917

journal_volume

26

pub_type

杂志文章
  • Are We Right to Consider Mesenchymal Stem Cells to Be a New Perspective for Patients with Juvenile Idiopathic Arthritis?

    abstract::Juvenile idiopathic arthritis (JIA) is the most common cause of chronic arthritis in childhood. Up to 50% of patients are resistant to standard therapy, which includes non-steroid anti-inflammatory drugs, corticosteroids, disease-modifying anti-rheumatic drugs and biologic therapies. Intra-articular injection of mesen...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章,评审

    doi:10.1007/s00005-017-0493-3

    authors: Orczyk K,Smolewska E

    更新日期:2018-08-01 00:00:00

  • Proliferation of human lymphocytes by mitogen stimulated cells.

    abstract::Lymphocytes cultured for three days with PHA or Con A were capable of inducing vigorous proliferation of autologous or allogeneic lymphocytes. Kinetics of the response varied with mitogen dose used for obtaining stimulating cells and with the ratio of stimulating to responder cells. A requirement for viable, mitogen-r...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Jaroszewski J,Kurpisz M,Brelińska-Peczalska R,Lastowska M

    更新日期:1978-01-01 00:00:00

  • The influence of trazodone on the circulatory system in patients with endogenous depression. I. Basic circulatory parameters.

    abstract::In patients with endogenous depression in remission, decline of systolic blood pressure and a statistically significant shortening of pulse time were found. ...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Mrozikiewicz A,Strzyzewski W,Kapelski Z,Sydor L

    更新日期:1976-01-01 00:00:00

  • Classification of cytokines according to the receptor code.

    abstract::A simple classification of cytokines is presented. It is based on voluminous information available from published papers of many outstanding researchers of the cytokines and their receptors and/or summarized by experts in this field. The cytokines are divided into 7 families according to their receptor code. Such arra...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章,评审

    doi:

    authors: Inglot AD

    更新日期:1997-01-01 00:00:00

  • Effect of complexes of lidocaine with transient metals on histamine release from rat mast cells.

    abstract::The effect of complexes of lidocaine with zinc, copper and cobalt on histamine release from peritoneal rat mast cells induced by various secretagogues was investigated. The complexes of lidocaine with metal ions inhibited histamine release induced by compound 48/80 and ionophoreous antibiotics: A23187 and X537A. The i...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Kazimierczak W,Bańkowska K,Adamas B,Lewa A,Maśliński C

    更新日期:1978-01-01 00:00:00

  • The distinctive role of small heat shock proteins in oncogenesis.

    abstract::Recently, the role of small heat shock proteins (HSPs) has been widely recognized in cancer research. Small HSPs are tumorprotective via numerous, independent mechanisms such as: oxidative stress, protection preventing protein denaturation, anti-apoptotic activity, and likely direct suppression of the immune system. H...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章,评审

    doi:10.1007/s00005-006-0013-3

    authors: Laudanski K,Wyczechowska D

    更新日期:2006-03-01 00:00:00

  • Correction to: Expanding Diversity and Common Goal of Regulatory T and B Cells. I: Origin, Phenotype, Mechanisms.

    abstract::The original article has been published without acknowledgment section. The acknowledgement section is given below for your reading. ...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s00005-017-0490-6

    authors: Bocian K,Kiernozek E,Domagała-Kulawik J,Korczak-Kowalska G,Stelmaszczyk-Emmel A,Drela N

    更新日期:2017-12-01 00:00:00

  • Complement and circulating immune complexes in children with mumps meningitis.

    abstract::Haemolytic activity of complement (CH50) and occurrence of circulating immune, complexes (CIC) were studied in serum samples from children with mumps meningitis taken at regular intervals. The decrease of CH50 was observed in 46 out of 77 samples (60%) in the Ist examination, between 1-6th day from the appearance of s...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Madaliński K,Imbs D,Gregorek H,Jankowski M,Ułanowicz G,Gut W,Kańtoch M

    更新日期:1984-01-01 00:00:00

  • Effect of immunosuppressive agents on the course of experimental syphilis in rabbits.

    abstract::Rabbits infected intradermally with T. pallidum at four sites on the clipped back were treated with cyclophosphamide, 1 mg/kg body weight, twice before and every two days after inoculation for five months, or 5-fluorouracil 2.5 mg/kg body weight, according to the same regimen. Humoral response, as measured repeatedly ...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Pacha J,Metzger M,Smogór W,Michalska E,Podwińska J,Ruczkowska J

    更新日期:1979-01-01 00:00:00

  • Interleukin 12 and direct cytotoxicity of spleen lymphocytes to Listeria innocua-phagocyting syngeneic macrophages in C57BL/6 and BALB/c mice.

    abstract::Production of interleukin 12 (IL-12) during cytotoxic reaction of C57BL/6 and BALB/c spleen lymphocytes or their subpopulations: T+B, T, CD4+ and CD8+ cells to L. innocua-phagocyting syngeneic macrophages was examined. The effector cell donors were untreated or L. innocua-infected. The number of surviving bacteria in ...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Szeliga J,Fiuk D,Walencka M,Gościcka T

    更新日期:1997-01-01 00:00:00

  • Tumorigenicity and metastatic ability of MmB16 mouse melanoma cell line and its two Aleuria aurantia agglutinin resistant variants.

    abstract::The availability of neoplastic cell lines with well defined growth characteristics has greatly facilitated study of the tumor phenotype, tumor progression and metastatic process. MmB16 cell line has been established in vitro from the B16 mouse melanoma serially passaged in C57BL/6 mice. From MmB16 cells two lectin-res...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Duś D,Matuszyk J,Kuśnierczyk H,Strzadała L,Radzikowski C

    更新日期:1992-01-01 00:00:00

  • Induction of specific tolerance by 15-deoxyspergualin (DOS) treatment after rat skin and kidney transplantation in rats. Analysis of effectivity of various protocols of DOS application.

    abstract::The purpose of this study was to analyse the effect of various protocols of 15-deoxyspergualin (DOS) application on skin or kidney graft survival. Following rat strain combinations were used: AS-->LEW (MHC identical/non-MHC-different) and DA-->LEW (MHC-different/non-MHC-different). Reference DOS dose was 2.5 mg/kg, i....

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Waaga AM,Krzymański M,Ulrichs K,Oko A,Müller-Ruchholtz W

    更新日期:1996-01-01 00:00:00

  • Immune Checkpoint Blockade in Cancer Immunotherapy: Mechanisms, Clinical Outcomes, and Safety Profiles of PD-1/PD-L1 Inhibitors.

    abstract::Programmed cell death protein 1 (PD-1) and its ligand PD-L1 are critical for the regulation of T cell exhaustion and activity suppression. Tumor cells expressing immune checkpoints including PD-L1 escape monitoring of T cells from the host immune system. Checkpoint inhibitors are highly promising therapies that functi...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章,评审

    doi:10.1007/s00005-020-00601-6

    authors: Yan Y,Zhang L,Zuo Y,Qian H,Liu C

    更新日期:2020-11-13 00:00:00

  • Immunomodulatory drugs as the stimulators of proliferative process.

    abstract::Stimulatory effect of immunomodulators on cellular proliferation was studied on the experimental model of regenerating rat liver. Thymus factor (TFX), isoprinosine and, to a lesser degree, levamisole, were observed to accelerate and enhance a compensative hypertrophy of the remaining lobes of liver. This phenomenon co...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Giełdanowski J

    更新日期:1983-01-01 00:00:00

  • TG and TnonG lymphocyte involvement in the proliferative response to PHA. I. Reactivity and regulatory functions of TG and TnonG subsets in the proliferative response of T lymphocytes.

    abstract::Both TG and TnonG subpopulations from human peripheral blood were found to secrete helper and suppressor factors for the PHA-induced T cell proliferative response. The TnonG subpopulation contained cells which were both able to secrete helper factor and to respond by proliferation, whereas in the TG subpopulation cell...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Markowicz S,Siwicki JK,Steffen JA

    更新日期:1987-01-01 00:00:00

  • Type I interferons as immunoregulatory molecules; implications for therapy in experimental autoimmune uveoretinitis.

    abstract::Clinical trials have shown that the type I interferon (IFN)-alpha/beta have some beneficial effects on organ-specific autoimmune diseases, such as Behcet's diseases and multiple sclerosis, although the precise mechanisms remain largely unresolved. T helper cells 1 (Th1)-mediated autoimmune responses are involved in th...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章,评审

    doi:

    authors: Mizuguchi J,Takeuchi M,Usui M

    更新日期:2002-01-01 00:00:00

  • Parallel examination of receptors of malignant lymphoma cells using combined tests with mouse erythrocytes and monoclonal VIB-C5 antibody or polyvalent serum against human immunoglobulins.

    abstract::This report presents the results of studies on two membrane markers of lymphocytes isolated from patients with non-Hodgkin's lymphoma. The combined methods were applied allowing for a simultaneous testing of: a) presence of the membrane receptor for mouse erythrocytes (Em) and membrane immunoglobulins (SmIg) or b) pre...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Krawczyk-Kuliś M,Hołowiecki J,Jarczok K,Duraj M

    更新日期:1984-01-01 00:00:00

  • Wratizolin ITCL in the treatment of herpes simplex and recurrent and zoster.

    abstract::Herpes simplex and zoster are frequent skin diseases of viral origin and the mechanism of their development as well as their course are not yet fully known. Fully effective methods of treating these diseases are not known. The authors evaluated the results of the externally applied ITCL preparation in the form of a 2%...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Moskalewska K,Dabrowska H,Rózański J,Grzywa Z

    更新日期:1983-01-01 00:00:00

  • The enzymatic activity of type 1 iodothyronine deiodinase (D1) is low in liver hemangioma: a preliminary study.

    abstract::Type 1 iodothyronine deiodinase (D1) is a crucial enzyme which converts the prohormone thyroxine (T4) into active tri-iodothyronine (T3). There has been strong evidence that the metabolism of thyroid hormones is disturbed in some neoplastic tissues such as thyroid, renal, and breast cancer. However, there are few avai...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:10.1007/s00005-009-0056-3

    authors: Kornasiewicz O,Debski M,Stepnowska M,Szałas A,Bar-Andziak E,Krawczyk M

    更新日期:2010-02-01 00:00:00

  • Prevalence of the intron 22 inversion of the factor VIII gene and inhibitor development in Polish patients with severe hemophilia A.

    abstract:INTRODUCTION:Patients with severe hemophilia A often develop inhibitors (antibodies) against transfused factor VIII. MATERIAL/METHODS:One hundred thirteen Polish patients with severe hemophilia A, who had been treated on demand with cryoprecipitate until 1992 and exclusively with factor VIII concentrates after 1995, w...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Sawecka J,Skulimowska J,Windyga J,Lopaciuk S,Kościelak J

    更新日期:2005-07-01 00:00:00

  • Immunopathogenic Background of Pars Planitis.

    abstract::Pars planitis is defined as an intermediate uveitis of unknown background of systemic disease with characteristic formations such as vitreous snowballs, snowbanks and changes in peripheral retina. The incidence of pars planitis varies 2.4-15.4 % of the uveitis patients. The pathogenesis of the disease is to be determi...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章,评审

    doi:10.1007/s00005-015-0361-y

    authors: Przeździecka-Dołyk J,Węgrzyn A,Turno-Kręcicka A,Misiuk-Hojło M

    更新日期:2016-04-01 00:00:00

  • Treatment of hairy cell leukemia patients with 2-chloro-2'-deoxyadenosine (2-CdA).

    abstract::A preliminary study of six hairy cell leukemia patients treated with one course of 2-chloro-2'-deoxyadenosine (2-CdA) is presented. 2-CdA was administered 0.1 mg/kg/daily by intravenous infusion over 7 days. Two patients achieved CR and four PR. ...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 临床试验,杂志文章

    doi:

    authors: Komarnicki M,Kaźmierczak M,Hansz J

    更新日期:1994-01-01 00:00:00

  • Macrophage migration inhibitory factor and its role in autoimmune diseases.

    abstract::After several decades of research into the macrophage migration inhibitory factor (MIF), its diverse actions in the immune system are yet to be fully revealed. What has become clear is that MIF plays an important role in both innate and adaptive immunity. However, while several pathways mediating the function of MIF i...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章,评审

    doi:

    authors: Denkinger CM,Metz C,Fingerle-Rowson G,Denkinger MD,Forsthuber T

    更新日期:2004-11-01 00:00:00

  • Quantitative real-time PCR in cancer research.

    abstract::In the era of the Human Genome Project, quantitation of gene expression by tumor/host cells is of paramount importance to investigate gene patterns responsible for cancer development, progression and response/resistance to treatment. Quantitative real-time PCR (qrt-PCR) technology has recently reached a level of sensi...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章,评审

    doi:

    authors: Mocellin S,Rossi CR,Marincola FM

    更新日期:2003-01-01 00:00:00

  • The influence of cystamine on pharmacokinetics and pharmacodynamics of thioridazine.

    abstract::A study on the influence of cystamine on the kinetics and dynamics of the action of thioridazine has been carried out. Higher levels of this drug in the blood and lower levels in the brain tissue than those in unpremedicated rats were determined. Half-life of thioridazine underwent shortening from 2-55 hr to 1-05 hr. ...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Wójciakowa Z,Kozaryn I

    更新日期:1976-01-01 00:00:00

  • The cytotoxic activity of heterologous anti-L-1210 antibodies conjugated with quinones.

    abstract::Biological effects of conjugates of quinone derivatives with antibodies were studied. Two methods of conjugation of aziridine derivatives of quinone with anti-L-1210 antibodies were used: the direct substitution of the protein amino groups or thiolation of immunoglobulins and subsequent substitution of the sulfhydryl ...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Boratyński J,Syper L

    更新日期:1983-01-01 00:00:00

  • Piroxicam in the treatment of immunologic, experimental inflammation of the anterior part of the eyeball.

    abstract::The efficacy of piroxicam was tested on the model of immunologic, experimental inflammation of the uveal tract. The inflammation of the anterior part of the eyeball was provoked in rabbits by the method of Böcke. Intensity of choroiditis was evaluated after second administration of homologous antigen. The preparation ...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Giełdanowski J

    更新日期:1988-01-01 00:00:00

  • The effect of cytostatic drugs on collagen metabolism in guinea pigs.

    abstract::Azathiprine (0.25 mg/100 g body wt.) and cyclophosphamide (0.2 mg/100 g body wt.) were administered to guinea pigs, orally every day during 4 weeks. Azathioprine caused a decrease in total collagen content in skin, liver and bone and decreased hydroxyproline and hydroxylysine concentration in blood serum, and urinary ...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Drózdz M,Kucharz E

    更新日期:1977-01-01 00:00:00

  • How does the major histocompatibility complex influence behavior?

    abstract::The major histocompatibility complex (MHC) encodes highly polymorphic cell surface glycoproteins that form the basis of immunological individuality. It has been postulated that MHC besides its role in immune defence also determines behavior through formation of specific odor cues. In addition several studies have impl...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章,评审

    doi:

    authors: Janssen E,Zavazava N

    更新日期:1999-01-01 00:00:00

  • Production of tumor necrosis factor alpha by resident peritoneal cells of mice.

    abstract::Freshly isolated resident peritoneal cells (RPC) of three mouse strains: BALB/c, NZB and C3H, release spontaneously small amounts of tumor necrosis factor (TNF) when cultured in vitro. RPC of BALB/c mice produced higher TNF levels than the cells isolated from two other strains (BALB/c > NZB > C3H). Lipopolysaccharide ...

    journal_title:Archivum immunologiae et therapiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Błach-Olszewska Z,Juszczyk M,Zaczyńska E

    更新日期:1993-01-01 00:00:00