Abstract：
:RNA-DNA saturation hybridization experiments were used to estimate the extent of transcription of repetitive DNA sequences in polyoma-transformed and nontransformed mouse cells in culture. Measurements were made with RNA from nontransformed cells in both the subconfluent and confluent stages of growth, transformed cells in normal growth medium, and transformed cells grown in medium containing 5-bromodeoxyuridine, 3 mu-g/ml, a treatment which reduces their tumorigenic potential. No differences were observed in the amount of repetitive DNA transcribed or in the families of sequences expressed, except in transformed cells grown in the presence of 5-bromodeoxyuridine, in which case the extent of transcription was reduced.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Grady LJ,Campbell WPsubject
Has Abstractpub_date
1975-06-01 00:00:00pages
1559-62issue
6eissn
0008-5472issn
1538-7445journal_volume
35pub_type
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