Serum angiotensin-converting enzyme is elevated in association with underground coal mining.

Abstract:

:Serum angiotensin-converting enzyme activity (SACE) and lysozyme activity were measured in a group of 40 underground coal miners and two control groups, 20 subjects with sarcoidosis and 15 normal non-dust-exposed volunteers. The miners were grouped first according to whether they had recent exposure (still actively mining or retired three years or less prior to measurement) or temporally more distant exposure (retired more than three years prior to measurement). Secondly, they were grouped as to whether or not they had coal workers' pneumoconiosis (CWP). The subjects with sarcoidosis were grouped according to disease activity. As expected, the subjects with active sarcoidosis had elevated SACE activity compared with normal subjects. The coal miners as a group did not have elevation of their SACE activity. However, the coal miners with recent exposure had elevated SACE activity (57.1 +/- 3.9 U/ml) compared with normal controls (43.8 +/- 1.5 U/ml, p = 0.007). The SACE activity in miners without recent exposure was not elevated (39.8 +/- 1.3 U/ml) compared with the normal controls. No increase in SACE activity was found when the miners were grouped according to the presence or absence of CWP. In contrast, the miners' serum lysozyme activity was not elevated. Since alveolar macrophages are a potential source of SACE, elevation of SACE activity in underground coal miners may reflect alveolar macrophage activation caused by increased pulmonary mixed coal mine dust burden. Furthermore, since both SACE and serum lysozyme are elevated in association with silicosis, these findings may confirm that the macrophage responses to inhaled silica and coal dust differ.

journal_name

Chest

journal_title

Chest

authors

Thompson AB,Cale WF,Lapp NL

doi

10.1378/chest.100.4.1042

subject

Has Abstract

pub_date

1991-10-01 00:00:00

pages

1042-5

issue

4

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)32503-X

journal_volume

100

pub_type

杂志文章

相关文献

CHEST文献大全
  • Idiopathic hypereosinophilic syndrome-related pulmonary involvement diagnosed by bronchoalveolar lavage.

    abstract::Patients with HES and pulmonary infiltrates may pose certain diagnostic problems as the infiltrates may be attributed to infection, infarction, congestive heart failure, or HES itself. We report an 87-year-old woman with idiopathic HES presenting with bibasal alveolar infiltrates. Differential cell count in BAL fluid ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.4.1178

    authors: Slabbynck H,Impens N,Naegels S,Dewaele M,Schandevyl W

    更新日期:1992-04-01 00:00:00

  • Increased CSF opioid activity in sleep apnea syndrome. Regression after successful treatment.

    abstract::The etiology of the SAS is unknown. To test whether endogenous opioids could be pathologically active in SAS, markers of opioid systems were measured in the CSF of 15 patients with SAS and in control subjects. Measured by receptor assay, the concentration of so-called fraction 1 opioid was higher in patients with SAS ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.96.2.250

    authors: Gislason T,Almqvist M,Boman G,Lindholm CE,Terenius L

    更新日期:1989-08-01 00:00:00

  • Maximum cardiac output during incremental exercise by first-pass radionuclide ventriculography.

    abstract:STUDY OBJECTIVE:To validate a noninvasive first-pass radionuclide ventriculographic (FPRV) measurement of maximum cardiac output (Qv) during exercise. DESIGN:Comparison of Qv to that measured by the Fick principle (Qf) at peak exercise. SETTING:Academic cardiopulmonary exercise laboratory. PATIENTS:Seventy-eight con...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.114.2.457

    authors: Maroni JM,Oelberg DA,Pappagianopoulos P,Boucher CA,Systrom DM

    更新日期:1998-08-01 00:00:00

  • Atrial fibrillation following pulse methylprednisolone therapy in an adult.

    abstract::The authors believe this to be the first case report of atrial fibrillation following pulse methylprednisolone therapy in an adult. The literature regarding the complications of pulse methylprednisolone therapy is reviewed, with particular emphasis on the incidence and pathogenesis of arrhythmias. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.2.622

    authors: McLuckie AE,Savage RW

    更新日期:1993-08-01 00:00:00

  • Prolonged reversible quadriparesis in mechanically ventilated patients who received long-term infusions of vecuronium.

    abstract::The use of neuromuscular blocking agents, particularly pancuronium, in patients receiving mechanical ventilation has been reported to cause prolonged paralysis and atrophy. We describe two mechanically ventilated patients with asthma who developed prolonged muscular weakness and atrophy after receiving the shorter-act...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.100.3.877

    authors: Margolis BD,Khachikian D,Friedman Y,Garrard C

    更新日期:1991-09-01 00:00:00

  • Pseudopseudotumor of the lung. Hepatic herniation into the right major fissure imitating a pseudotumor on chest roentgenogram.

    abstract::A young man presented to us with an asymptomatic ovoid mass which appeared to be in the right major fissure. The roentgenographic appearance of the lesion was that of a pseudotumor. The computerized tomography scan suggested tissue density leading to exploration. At surgery, we found the mass to be a portion of liver ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.78.2.346

    authors: Fanta CH,Kacoyanis GP,Koster JK Jr,McFadden ER Jr

    更新日期:1980-08-01 00:00:00

  • Worsening of vasovagal syncope after beta-blocker therapy.

    abstract::Head-up tilt test was done in a 27-year-old man with recurrent syncope of unexplained cause. Severe sinus bradycardia and hypotension accompanied by light-headedness, cold sweating, and nausea occurred at 80 degrees head-up position during 4 micrograms/min isoproterenol infusion. Oral propranolol, 160 mg/d, in four di...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.106.3.963

    authors: Wang CC,Yeh SJ,Wen MS,Lin FC,Wu D

    更新日期:1994-09-01 00:00:00

  • Prognostic Value of 6-Min Walk Test to Predict Postoperative Cardiopulmonary Complications in Patients With Non-small Cell Lung Cancer.

    abstract:BACKGROUND:The risk stratification value of the 6-min walk test (6MWT) to decide the feasibility of surgical resection is not well elucidated in patients with non-small cell lung cancer (NSCLC) and moderately decreased lung function. OBJECTIVE:This study aimed to determine the role of the 6MWT in predicting postoperat...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2019.12.039

    authors: Lee H,Kim HK,Kang D,Kong S,Lee JK,Lee G,Shin S,Cho J,Zo JI,Shim YM,Park HY

    更新日期:2020-06-01 00:00:00

  • Circulating Endometrial Cells in Women With Spontaneous Pneumothorax.

    abstract:BACKGROUND:The occurrence of catamenial pneumothorax (CP) is rare, and the awareness of this diagnosis among physicians is insufficient. CP is highly correlated with pelvic endometriosis and remains the most common form of thoracic endometriosis syndrome. Circulating endometrial cells (CECs) have been previously detect...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2019.09.008

    authors: Kiss I,Pospisilova E,Kolostova K,Maly V,Stanek I,Lischke R,Schutzner J,Pawlak I,Bobek V

    更新日期:2020-02-01 00:00:00

  • A Case of Lymphangiomatosis With Infected Lymphangiomas Effectively Treated by Thoracoscopic Debridement and Drainage.

    abstract::A 40-year-old woman with lymphangiomatosis also had an intrathoracic lymphangioma infection. Since the age of 8 years, the patient had undergone repeated abdominal and mediastinal cyst surgeries and had received a diagnosis of lymphangiomatosis. At this time, she showed a high fever of 38.5°C. Cultures of both blood a...

    journal_title:Chest

    pub_type:

    doi:10.1016/j.chest.2020.06.048

    authors: Minakata T,Suzuki T,Kamio Y,Kadokura M,Himuro N,Takei H

    更新日期:2020-11-01 00:00:00

  • Distribution of bronchial nonspecific reactivity in the general population.

    abstract::We investigated 654 subjects of a small Lombardy (Italy) town between 15 and 64 years of age who were representative of the general population. By clinical examination, the sample included 535 normal subjects (164 normal smokers, 341 normal nonsmokers, 30 normal subjects with acute upper respiratory illness within 30 ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.93.1.26

    authors: Cerveri I,Bruschi C,Zoia MC,Zanon P,Maccarini L,Grassi M,Rampulla C

    更新日期:1988-01-01 00:00:00

  • The snoring spectrum: acoustic assessment of snoring sound intensity in 1,139 individuals undergoing polysomnography.

    abstract:STUDY OBJECTIVES:To quantify the snoring sound intensity levels generated by individuals during polysomnographic testing and to examine the relationships between acoustic, polysomnographic, and clinical variables. DESIGN:The prospective acquisition of acoustic and polysomnographic data with a retrospective medical cha...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.115.3.762

    authors: Wilson K,Stoohs RA,Mulrooney TF,Johnson LJ,Guilleminault C,Huang Z

    更新日期:1999-03-01 00:00:00

  • Inhalation challenge with sulfidopeptide leukotrienes in human subjects.

    abstract::What is the meaning of these findings to the practicing chest physician? First, leukotrienes are potent airway constrictors; they are capable of reproducing the type of airway constriction observed in asthma. The role of leukotrienes in this regard has yet to be established, but experiments to test the importance of t...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.89.3.414

    authors: Drazen JM

    更新日期:1986-03-01 00:00:00

  • Transbronchial lung biopsy via the fiberoptic bronchoscope. Experience with 107 consecutive cases and comparison with bronchial brushing.

    abstract::Transbronchial lung biopsy (TBB) was performed during fiberoptic bronchoscopy under fluoroscopic guidance in 107 patients. TBB was diagnostic in 17 of 21 (81 percent) cases with localized malignant lesions greater than 4 cm in diameter and bronchial brushing was positive in 12 (57 percent). TBB was diagnostic in 14 of...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.68.4.524

    authors: Ellis JH Jr

    更新日期:1975-10-01 00:00:00

  • Bed partners' assessment of nasal continuous positive airway pressure therapy in obstructive sleep apnea.

    abstract:STUDY OBJECTIVE:This study aimed to evaluate the effects of nasal continuous positive airway pressure (nCPAP) therapy on sleep and daytime symptoms of bed partners and patients with obstructive sleep apnea (OSA). DESIGN:A cross-sectional questionnaire survey. SETTING:The sleep laboratory of a university teaching hosp...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.111.5.1261

    authors: Kiely JL,McNicholas WT

    更新日期:1997-05-01 00:00:00

  • Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea: a 12-week, open-label study.

    abstract:STUDY OBJECTIVES:The purpose of this 12-week study was to evaluate the efficacy and safety of adjunct modafinil to treat excessive sleepiness in patients with obstructive sleep apnea (OSA) who experience residual sleepiness despite regular nasal continuous positive airway pressure (nCPAP) use. DESIGN:Twelve-week, open...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1378/chest.124.6.2192

    authors: Schwartz JR,Hirshkowitz M,Erman MK,Schmidt-Nowara W

    更新日期:2003-12-01 00:00:00

  • Metastatic renal cell carcinoma. An unusual cause of syncope.

    abstract::A 77-year-old man with a history of renal cell carcinoma presented with orthostatic syncope. Investigation revealed metastatic carcinoma in the left lung extending through the pulmonary veins into the left atrium obstructing the mitral orifice. On review of the literature, this case appears to be the first to describe...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.98.2.481

    authors: Fogel RI,Balady GJ,Klein MD,Rajaii-Khorasani A

    更新日期:1990-08-01 00:00:00

  • Metastatic malignant melanoma presenting clinically as obstruction of the right ventricular inflow and outflow tracts. Characterization by magnetic resonance imaging.

    abstract::Metastatic disease involving the heart may present in a variety of fashions. A patient with melanoma metastatic to the right ventricle which was diagnosed clinically by evidence of recent onset of right ventricular inflow and outflow tract obstruction is described. Important information regarding the extent of the met...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.92.2.362

    authors: Emmot WW,Vacek JL,Agee K,Moran J,Dunn MI

    更新日期:1987-08-01 00:00:00

  • Increased expression of leukocyte function associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1) by alveolar macrophages of patients with pulmonary sarcoidosis.

    abstract::Leukocyte function associated antigen-1 (LFA-1) and its ligand intercellular adhesion molecule-1 (ICAM-1) are cell adhesion molecules that play an important role in the capacity of monoculear phagocytes (MPs) to present antigens to T lymphocytes. Since in pulmonary sarcoidosis (PS) this capacity is increased at sites ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.100.4.910

    authors: Melis M,Gjomarkaj M,Pace E,Malizia G,Spatafora M

    更新日期:1991-10-01 00:00:00

  • Pulse pressure and cardiovascular events in postmenopausal women with coronary heart disease.

    abstract:BACKGROUND:Pulse pressure (PP) has been shown to predict risk for cardiovascular events in men; however, this association has not been well established in women. Hormone replacement therapy may improve arterial compliance, but findings from cross-sectional and prospective studies report inconsistent results. We sought ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.127.5.1498

    authors: Nair GV,Chaput LA,Vittinghoff E,Herrington DM,Heart and Estrogen\/Progestin Replacement Study Investigators.

    更新日期:2005-05-01 00:00:00

  • Clinical Prognosis of Nonmassive Central and Noncentral Pulmonary Embolism: A Registry-Based Cohort Study.

    abstract:BACKGROUND:Whether the localization of nonmassive pulmonary embolism (PE) is associated with the short-term and long-term prognosis of patients remains unknown. Our aim was to characterize associations of nonmassive PE localization with risks of recurrent VTE, major bleeding, and mortality during and after anticoagulat...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.chest.2016.10.056

    authors: Gouin B,Blondon M,Jiménez D,Fernández-Capitán C,Bounameaux H,Soler S,Duce R,Sahuquillo JC,Ruiz-Giménez N,Monreal M,RIETE investigators.

    更新日期:2017-04-01 00:00:00

  • Sex differences in response to tadalafil in pulmonary arterial hypertension.

    abstract:BACKGROUND:Pulmonary arterial hypertension (PAH) is a progressive disease with high rates of morbidity and mortality. Current therapies improve symptoms, functional capacity, and, in select cases, survival. Little is known about patient factors that may predict the likelihood of patient-important, clinically relevant r...

    journal_title:Chest

    pub_type: 杂志文章,随机对照试验

    doi:10.1378/chest.14-0263

    authors: Mathai SC,Hassoun PM,Puhan MA,Zhou Y,Wise RA

    更新日期:2015-01-01 00:00:00

  • D-dimer in acute aortic dissection.

    abstract:STUDY OBJECTIVE:Laboratory testing plays a minor role in the assessment of aortic dissection. Its main value is in the exclusion of other diseases. Following an incidental observation, we systematically investigated the relationship between elevated d-dimer levels and acute aortic dissection. DESIGN:We prospectively t...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.123.5.1375

    authors: Weber T,Högler S,Auer J,Berent R,Lassnig E,Kvas E,Eber B

    更新日期:2003-05-01 00:00:00

  • Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies.

    abstract:BACKGROUND:Recent study of the inflammatory reactions occurring during and after cardiopulmonary bypass (CPB) has improved our understanding of the involvement of the inflammatory cascade in perioperative injury. However, the exact mechanisms of this complex response remain to be fully determined. METHODS:Literature o...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.112.3.676

    authors: Wan S,LeClerc JL,Vincent JL

    更新日期:1997-09-01 00:00:00

  • Sleep medicine training across the spectrum.

    abstract::There is now a new pathway and examination for sleep medicine, sponsored by the American Board of Internal Medicine, and a number of accredited sleep medicine fellowship programs through the Accreditation Council for Graduate Medical Education. This review takes an historical approach to discuss the process of educati...

    journal_title:Chest

    pub_type: 历史文章,杂志文章,评审

    doi:10.1378/chest.10-0783

    authors: Strohl KP

    更新日期:2011-05-01 00:00:00

  • Physiologic effects and side effects of prostaglandin E1 in the adult respiratory distress syndrome.

    abstract::Because PGE1 previously has been reported to increase survival of patients with ARDS, we evaluated physiologic effects and side effects of PGE1 in a prospective open-label study of patients with ARDS. Seventeen patients with ARDS who did not have significant renal or hepatic dysfunction received PGE1 by continuous cen...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.97.3.684

    authors: Russell JA,Ronco JJ,Dodek PM

    更新日期:1990-03-01 00:00:00

  • Delayed perforation of the esophagus by a closed thoracostomy tube.

    abstract::We report on a previously undocumented complication of a trocar-free thoracostomy tube--delayed perforation of a normal esophagus. The complication presented clinically with fever and copious enteric drainage four days after thoracostomy tube insertion. Diagnosis was established by a contrast study of the esophagus. R...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.6.1897

    authors: Shapira OM,Aldea GS,Kupferschmid J,Shemin RJ

    更新日期:1993-12-01 00:00:00

  • OSA and pulmonary hypertension: time for a new look.

    abstract::OSA is a common yet underdiagnosed disorder encountered in everyday practice. The disease is a unique physiologic stressor that contributes to the development or progression of many other disorders, particularly cardiovascular conditions. The pulmonary circulation is specifically affected by the intermittent hypoxic a...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.14-0614

    authors: Ismail K,Roberts K,Manning P,Manley C,Hill NS

    更新日期:2015-03-01 00:00:00

  • Effect of weight loss on the ECG of normotensive morbidly obese patients.

    abstract:BACKGROUND:Morbid obesity produces a variety of ECG alterations, including leftward shifts of the P-wave, QRS, and T-wave axes; disproportionately high frequencies of low QRS voltage; left ventricular hypertrophy and left atrial abnormality; and a high frequency of T-wave flattening in the inferior and lateral leads. T...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.119.2.507

    authors: Alpert MA,Terry BE,Hamm CR,Fan TM,Cohen MV,Massey CV,Painter JA

    更新日期:2001-02-01 00:00:00

  • Release of lipopolysaccharide toxicity-modulating proteins in patients undergoing cardiopulmonary bypass using noncoated and heparin-coated extracorporeal circuits. A clinical pilot study.

    abstract:STUDY OBJECTIVE:Cardiopulmonary bypass (CPB) induces a generalized inflammatory response, including activation of leukocytes, contributing to postoperative morbidity. The inflammatory pathways leading to this systemic inflammatory response syndrome are considered identical to those involved in septic shock. Therefore, ...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.111.3.577

    authors: Bouma M,Maessen J,Weerwind P,Dentener M,Fransen E,de Jong D,Buurman W

    更新日期:1997-03-01 00:00:00