Prolonged reversible quadriparesis in mechanically ventilated patients who received long-term infusions of vecuronium.

Abstract:

:The use of neuromuscular blocking agents, particularly pancuronium, in patients receiving mechanical ventilation has been reported to cause prolonged paralysis and atrophy. We describe two mechanically ventilated patients with asthma who developed prolonged muscular weakness and atrophy after receiving the shorter-acting agent vecuronium. These cases illustrate the potential of any neuromuscular blocking agent to cause these complications, especially in patients who are immobile, have decreased renal or liver function, or receive concomitant myotoxic agents.

journal_name

Chest

journal_title

Chest

authors

Margolis BD,Khachikian D,Friedman Y,Garrard C

doi

10.1378/chest.100.3.877

subject

Has Abstract

pub_date

1991-09-01 00:00:00

pages

877-8

issue

3

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)32841-0

journal_volume

100

pub_type

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