Abstract:
:A recurring objective in longitudinal studies on aging and longevity has been the investigation of the relationship between age-at-death and current values of a longitudinal covariate trajectory that quantifies reproductive or other behavioral activity. We propose a novel technique for predicting age-at-death distributions for situations where an entire covariate history is included in the predictor. The predictor trajectories up to current time are represented by time-varying functional principal component scores, which are continuously updated as time progresses and are considered to be time-varying predictor variables that are entered into a class of time-varying functional regression models that we propose. We demonstrate for biodemographic data how these methods can be applied to obtain predictions for age-at-death and estimates of remaining lifetime distributions, including estimates of quantiles and of prediction intervals for remaining lifetime. Estimates and predictions are obtained for individual subjects, based on their observed behavioral trajectories, and include a dimension-reduction step that is implemented by projecting on a single index. The proposed techniques are illustrated with data on longitudinal daily egg-laying for female medflies, predicting remaining lifetime and age-at-death distributions from individual event histories observed up to current time.
journal_name
Biometricsjournal_title
Biometricsauthors
Müller HG,Zhang Ydoi
10.1111/j.1541-0420.2005.00378.xsubject
Has Abstractpub_date
2005-12-01 00:00:00pages
1064-75issue
4eissn
0006-341Xissn
1541-0420pii
BIOM378journal_volume
61pub_type
杂志文章相关文献
BIOMETRICS文献大全abstract::The accuracy of a new diagnostic test is often determined by comparison with a reference test which also has unknown error rates. Maximum likelihood estimation of the error rates of both tests is possible if they are simultaneously applied to two populations with different disease prevalences. The estimation procedure...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1985-12-01 00:00:00
abstract::A method is developed for obtaining tree-structured relative risk estimates for censored survival data. The first step of a full likelihood estimation procedure is used in a recursive partitioning algorithm that adopts most aspects of the widely used Classification and Regression Tree (CART) algorithm of Breiman et al...
journal_title:Biometrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1992-06-01 00:00:00
abstract::A method is proposed for calculating the probabilities of assignment of a patient to treatments; it involves minimizing a quadratic criterion subject to a balance constraint. The optimal probabilities are very easy to compute. Numerical illustration is given and comparisons are drawn with the entropy-based methods of ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1983-12-01 00:00:00
abstract::ChIP-chip (or ChIP-on-chip) is a technology for isolation and identification of genomic sites occupied by specific DNA-binding proteins in living cells. The ChIP-chip signals can be obtained over the whole genome by tiling arrays, where a peak shape is generally observed around a protein-binding site. In this article,...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2007.00768.x
更新日期:2007-09-01 00:00:00
abstract::Heart rate oscillates in synchrony with respiration. Several methods have been employed to assess this 'sinus arrhythmia', as an index of autonomic nervous system function. This paper proposes a new, easily computed measure, R, which is relatively resistant to the major nonrespiratory sources of variation, including p...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1984-09-01 00:00:00
abstract::In practice, when analyzing data from a capture-recapture experiment it is tempting to apply modern advanced statistical methods to the observed capture histories. However, unless the analysis takes into account that the data have only been collected from individuals who have been captured at least once, the results m...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2011.01596.x
更新日期:2011-12-01 00:00:00
abstract::The log-rank test is widely used to compare two survival distributions in a randomized clinical trial, while partial likelihood (Cox, 1975) is the method of choice for making inference about the hazard ratio under the Cox (1972) proportional hazards model. The Wald 95% confidence interval of the hazard ratio may inclu...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12528
更新日期:2016-12-01 00:00:00
abstract::Ranked set sampling (RSS) utilizes inexpensive auxiliary information about the ranking of the units in a sample to provide a more precise estimator of the population mean of the variable of interest Y, which is either difficult or expensive to measure. However, the ranking may not be perfect in most situations. In thi...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract::Power and sample-size formulas for testing the homogeneity of relative risks using the score method are presented. The homogeneity score test (Gart, 1985, Biometrika 72, 673-677) is formally equivalent to the Pearson chi-square test, although they look different. Results of this paper may be useful in assessing the va...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.1999.00289.x
更新日期:1999-03-01 00:00:00
abstract:SUMMARY:We consider the analysis of clinical trials that involve randomization to an active treatment (T = 1) or a control treatment (T = 0), when the active treatment is subject to all-or-nothing compliance. We compare three approaches to estimating treatment efficacy in this situation: as-treated analysis, per-protoc...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2008.01066.x
更新日期:2009-06-01 00:00:00
abstract::Interference occurs between individuals when the treatment (or exposure) of one individual affects the outcome of another individual. Previous work on causal inference methods in the presence of interference has focused on the setting where it is a priori assumed that there is "partial interference," in the sense that...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.13125
更新日期:2020-03-01 00:00:00
abstract::Cancer population studies based on cancer registry databases are widely conducted to address various research questions. In general, cancer registry databases do not collect information on cause of death. The net survival rate is defined as the survival rate if a subject would not die for any causes other than cancer....
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12568
更新日期:2017-03-01 00:00:00
abstract::An adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations. The test statistic is a direct statistical analogue of the popular "funnel-graph." The number of component studies in the meta-analysis, the...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::Consider a collection of spatially clustered objects where the clusters are geographically rare. Of interest is estimation of the total number of objects on the site from a sample of plots of equal size. Under these spatial conditions, adaptive cluster sampling of plots is generally useful in improving efficiency in e...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2000.00503.x
更新日期:2000-06-01 00:00:00
abstract::Alterations in DNA methylation have been linked to the development and progression of many diseases. The bisulfite sequencing technique presents methylation profiles at base resolution. Count data on methylated and unmethylated reads provide information on the methylation level at each CpG site. As more bisulfite sequ...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.13000
更新日期:2019-06-01 00:00:00
abstract::Methods for modeling and mapping spatial variation in disease risk continue to motivate much research. In particular, spatial analyses provide a useful tool for exploring geographical heterogeneity in health outcomes, and consequently can yield clues as to disease etiology, direct public health management, and generat...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2008.01193.x
更新日期:2009-12-01 00:00:00
abstract::In this study we are concerned with the construction of confidence intervals for the conditional probability of misallocation associated with Anderson's classification statistics, W. The available methods of computing confidence intervals for the conditional probability are not satisfactory in practice, mainly because...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract::Receiver operating characteristic (ROC) analysis is widely used to evaluate the performance of diagnostic tests with continuous or ordinal responses. A popular study design for assessing the accuracy of diagnostic tests involves multiple readers interpreting multiple diagnostic test results, called the multi-reader, m...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12240
更新日期:2014-12-01 00:00:00
abstract::The objective of this article is to develop a hypothesis-testing procedure to determine whether a common source outbreak has ended. We consider the case when neither the calendar date of exposure to the pathogen nor the exact incubation period distribution is known. The hypothesis-testing procedure is based on the spa...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2005.00421.x
更新日期:2006-03-01 00:00:00
abstract::One common method for estimating total catch is to multiply an estimate for CPUE, the catch per unit effort, by an estimate of total effort obtained from an independent second survey. In general, estimating total effort requires that sample times are chosen at random over the full fishing period; however, in practice,...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2001.00461.x
更新日期:2001-06-01 00:00:00
abstract::A Bayesian multivariate adaptive regression spline fitting approach is used to model univariate and multivariate survival data with censoring. The possible models contain the proportional hazards model as a subclass and automatically detect departures from this. A reversible jump Markov chain Monte Carlo algorithm is ...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.1999.01071.x
更新日期:1999-12-01 00:00:00
abstract::In this article, we investigate clustering methods for multilevel functional data, which consist of repeated random functions observed for a large number of units (e.g., genes) at multiple subunits (e.g., bacteria types). To describe the within- and between variability induced by the hierarchical structure in the data...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2011.01714.x
更新日期:2012-09-01 00:00:00
abstract::The estimation of maternal genetic variances by a multivariate maximum likelihood method is discussed. As an illustration the method is applied to data on Tribolium using a model based on partitioning the maternal genetic effect into additive and dominance components. An alternative model due to Falconer (1965) is als...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1976-12-01 00:00:00
abstract::The paper here presented was motivated by a case study involving high-dimensional and high-frequency tidal volume traces measured during induced panic attacks. The focus was to develop a procedure to determine the significance of whether a mean curve dominates another one. The key idea of the suggested method relies o...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2007.00959.x
更新日期:2008-09-01 00:00:00
abstract::Brain connectivity analysis is now at the foreground of neuroscience research. A connectivity network is characterized by a graph, where nodes represent neural elements such as neurons and brain regions, and links represent statistical dependence that is often encoded in terms of partial correlation. Such a graph is i...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12633
更新日期:2017-09-01 00:00:00
abstract::Life-table methodology for interval-censored survival times is used to estimate marginal survival probabilities from data consisting of independent cohorts of correlated responses. We restrict our attention to situations where response times within cohorts are exchangeable and the marginal survival distributions are t...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract::Conventional statistical determinations of sample size in phase II studies typically lead to sample sizes of the order of 25 (Schoenfeld, 1980, International Journal of Radiation Oncology, Biology and Physics 6, 371-374). When the development of new treatments is proceeding rapidly relative to the recruitment of suita...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1985-06-01 00:00:00
abstract::We propose a new estimation method for multivariate failure time data using the quadratic inference function (QIF) approach. The proposed method efficiently incorporates within-cluster correlations. Therefore, it is more efficient than those that ignore within-cluster correlation. Furthermore, the proposed method is e...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2009.01307.x
更新日期:2010-06-01 00:00:00
abstract::A class of adaptive weighted log-rank statistics is described where the vector of weights is chosen in a data-dependent way from a family of "smooth" weight vectors. A parametric family of weight vectors is identified which includes most shapes of weighting vectors that will be near optimal in many cancer prevention a...
journal_title:Biometrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-09-01 00:00:00
abstract::Gene-disease association studies based on case-control designs may often be used to identify candidate polymorphisms (markers) conferring disease risk. If a large number of markers are studied, genotyping all markers on all samples is inefficient in resource utilization. Here, we propose an alternative two-stage metho...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341X.2004.00207.x
更新日期:2004-09-01 00:00:00