Improving access to renal transplantation.


:Kidney transplantation is the treatment of choice for most patients with end-stage renal disease (ESRD), with success rates greater than were envisioned as recently as a decade ago. Unfortunately this trend has created unprecedented demand for transplantable organs and new challenges for those desiring transplantation. This report is an overview of this changing landscape, with a focus on the clinical implications of the current process that culminates in renal transplantation. It also highlights potential solutions to overcome these newly recognized obstacles.


Semin Dial


Seminars in dialysis


Gaston RS




Has Abstract


2005-11-01 00:00:00














  • The ADEMEX study and its implications for peritoneal dialysis adequacy.

    abstract::In an attempt to improve patient outcomes in peritoneal dialysis (PD), national organizations (such as the National Kidney Foundation Dialysis Outcomes Quality Initiative [NKF-DOQI] process) have formulated clinical practice guidelines based on clinical evidence available at the time of development. For "adequacy" of ...

    journal_title:Seminars in dialysis

    pub_type: 评论,社论


    authors: Burkart JM

    更新日期:2003-01-01 00:00:00

  • Prediction of Arteriovenous Fistula Dysfunction: Can it be Taught?

    abstract::Physical examination (PE) is an excellent means of predicting arteriovenous fistula (AVF) dysfunction. Although quick and inexpensive, PE is seldom used as a tool to assess stenosis by general nephrologists, dialysis nurses, and dialysis technicians. Previous studies have demonstrated that PE can be taught to interven...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章


    authors: Rosenberg JE,Yevzlin AS,Chan MR,Valliant AM,Astor BC

    更新日期:2015-09-01 00:00:00

  • Changing dialysate composition to optimize acid-base therapy.

    abstract::In response to rapid alkali delivery during hemodialysis, hydrogen ions (H+ ) are mobilized from body buffers and from stimulation of organic acid production in amounts sufficient to convert most of the delivered bicarbonate to CO2 and water. Release of H+ from nonbicarbonate buffers serves to back-titrate them to a m...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Sargent JA,Marano M,Marano S,Gennari FJ

    更新日期:2019-05-01 00:00:00

  • Assessing the Adequacy of Small Solute Clearance for Various Dialysis Modalities, with Inclusion of Residual Native Kidney Function.

    abstract::Measurement of small molecule clearance remains important in the clinical care of patients requiring long-term dialysis. Many patients maintain a significant degree of residual native kidney function and may have nontraditional schedules with or without combined dialysis modalities. In this review, we examine and outl...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Chin AI,Depner TA,Daugirdas JT

    更新日期:2017-05-01 00:00:00

  • Euvolemia-A critical target in the management of acute kidney injury.

    abstract::It has been clearly established that critically ill patients with sepsis require prompt fluid resuscitation. The optimal amount of fluid and when to taper this resuscitation is less clear. There is a growing evidence that fluid overload leads to acute kidney injury, and increased morbidity and mortality. A clinician's...

    journal_title:Seminars in dialysis

    pub_type: 社论,评审


    authors: Colbert GB,Szerlip HM

    更新日期:2019-01-01 00:00:00

  • Beta blockers in patients with end-stage renal disease-Evidence-based recommendations.

    abstract::For patients who require hemodialysis, beta blockers offer a simultaneous opportunity and challenge in the treatment of cardiovascular disease. Beta blockers are well supported by data from nondialysis populations and directly mitigate the sympathetic overactivity that links chronic kidney disease with cardiovascular ...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Weir MA,Herzog CA

    更新日期:2018-05-01 00:00:00

  • Do ketoanalogues still have a role in delaying dialysis initiation in CKD predialysis patients?

    abstract::Early versus later start of dialysis is still a matter of debate. Low-protein diets have been used for many decades to delay dialysis initiation. Protein-restricted diets (0.3-0.6 g protein/kg/day) supplemented with essential amino acids and ketoanalogues (sVLPD) can be offered, in association with pharmacological tre...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Aparicio M,Bellizzi V,Chauveau P,Cupisti A,Ecder T,Fouque D,Garneata L,Lin S,Mitch W,Teplan V,Yu X,Zakar G

    更新日期:2013-11-01 00:00:00

  • Cardiovascular adaptations associated with exercise in patients on hemodialysis.

    abstract::Patients on hemodialysis are physically inactive. Less than 50% of hemodialysis patients undertake exercise once a week and such patients have increased mortality compared to patients who undertake regular exercise. The reasons for physical inactivity and reduced functional capacity are complex and inter-related, with...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Graham-Brown MPM,Jardine MJ,Burton JO

    更新日期:2019-07-01 00:00:00

  • Dialysis in pregnant women with chronic kidney disease.

    abstract::Pregnancy occurs uncommonly in women with chronic kidney disease (CKD) and fetal outcome tends to be poor, with high rates of prematurity and mortality. Dialysis, by complementing residual renal function, may improve fetal outcome in pregnant women with CKD. Although there are no prospective or randomized trials that ...

    journal_title:Seminars in dialysis

    pub_type: 社论,评审


    authors: Shemin D

    更新日期:2003-09-01 00:00:00

  • Baxter Aurora dialysis system.

    abstract::With the recent focus on the benefits of more frequent dialysis, the Baxter Aurora dialysis system provides maximum flexibility for therapy prescription, including short daily treatments, long nocturnal treatments, hemodialysis, hemofiltration, and online hemodiafiltration, all in a compact, reliable, easy to use syst...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章


    authors: Kelly TD

    更新日期:2004-03-01 00:00:00

  • Comments on plasma parathyroid hormone levels and their relationship to bone histopathology among patients undergoing dialysis.

    abstract::Measurements of the concentration of parathyroid hormone (PTH) in serum or plasma are used widely for the initial diagnostic assessment of patients with renal bone disease, to monitor disease progression, and to gauge responses to treatment. Several analytical methods are used to measure plasma PTH levels, and a varie...

    journal_title:Seminars in dialysis

    pub_type: 社论,评审


    authors: Goodman WG

    更新日期:2007-01-01 00:00:00

  • A novel technique for tethered dialysis catheter removal using the laser sheath.

    abstract::Traction and cutdown techniques can successfully remove a tunneled dialysis catheter (TDC) in a great majority of patients. However, these methods may not be successful in patients with catheters that are tethered or attached to the central veins or the atrium. A forceful application of traction can lead to catheter b...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章


    authors: Carrillo RG,Garisto JD,Salman L,Merrill D,Asif A

    更新日期:2009-11-01 00:00:00

  • Dialysis access failure: an indication for immediate kidney transplantation.

    abstract::In the United States, presently there are more than 50,000 patients with end-stage renal disease (ESRD) awaiting a cadaveric kidney and each year less than a quarter receive kidney transplantation. Although the real incidence in unknown, a significant number of these patients die due to lack of dialysis access. While ...

    journal_title:Seminars in dialysis

    pub_type: 社论


    authors: Laskow DA,Ahsan N

    更新日期:2002-01-01 00:00:00

  • The economic burden of geriatric ESRD.

    abstract::The elderly represent the fastest growing segment of incident patients entering end-stage renal disease (ESRD). Increasingly, social scientists and caregivers are faced with changing models of care, which will challenge traditional patterns of patient acceptance into costly medical therapies. This paper analyzes the o...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章


    authors: Parker TF 3rd

    更新日期:2012-11-01 00:00:00

  • Ultrapure dialysate: a desirable and achievable goal for routine hemodialysis.

    abstract::United States standards for the microbiologic quality of dialysate are not very stringent and have remained unchanged for more than 20 years, despite significant changes in the patient population and in the technology of hemodialysis. Numerous studies have demonstrated that bacterial products can cross dialysis membra...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章


    authors: Ward RA

    更新日期:2000-11-01 00:00:00

  • A survey of current procedural practices of Australian and New Zealand nephrologists.

    abstract::The aim of this study was to describe the range and extent of current procedural practices of Nephrologists and trainees in Australia and New Zealand with a specific focus on renal biopsy. A web-based survey was constructed based on a 2009 pilot survey conducted by the authors. The survey was distributed by email. A t...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章


    authors: Ritchie AG,Saunders J,Baer R,May S,Australian and New Zealand Special Interest Group in Interventional Nephrology Research Collaboration.

    更新日期:2013-11-01 00:00:00

  • Transplantation in diabetic kidney failure patients: modalities, outcomes, and clinical management.

    abstract::Diabetes mellitus (DM) is a common and devastating disease, affecting up to 19.3 million Americans. It is the leading cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) in the United States. Diabetic patients with ESRD have a high incidence of cardiovascular disease and death. For those kidney tr...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Luan FL,Samaniego M

    更新日期:2010-03-01 00:00:00

  • Dialysis membrane and modality in acute renal failure: understanding discordant meta-analyses.

    abstract::Meta-analyses of the published literature are increasingly being used, allowing similar clinical trials to be combined quantitatively, thereby increasing the precision of the estimation of treatment effect. Four meta-analyses were recently published comparing the impact of dialysis membranes or dialysis modality on cl...

    journal_title:Seminars in dialysis

    pub_type: 社论,评审


    authors: Teehan GS,Liangos O,Lau J,Levey AS,Pereira BJ,Jaber BL

    更新日期:2003-09-01 00:00:00

  • Peritoneal dialysis in acute kidney injury: lessons learned and applied.

    abstract::Peritoneal dialysis (PD) is a simple, safe, gentle, and efficient renal replacement therapy (RRT) method. It is able to correct acute kidney injury (AKI)-induced metabolic, electrolytic, and acid-base disorders and volume overload both in and out the intensive care unit setting. Some PD modalities, such as high-volume...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Burdmann EA,Chakravarthi R

    更新日期:2011-03-01 00:00:00

  • Eliminating the need for routine monthly postdialysis serum urea nitrogen measurement: A method for monitoring Kt/V and normalized protein catabolic rate using conductivity determined dialyzer clearance.

    abstract::Many dialysis machines can compute dialyzer sodium clearances at multiple time points during a dialysis treatment using conductivity. For a given treatment, the average dialyzer sodium clearance (K), when combined with treatment time (t), and the estimated urea distribution volume (V, usually based on either anthropom...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章


    authors: Daugirdas JT

    更新日期:2018-11-01 00:00:00

  • Peritoneal dialysis underutilization: the impact of an interventional nephrology peritoneal dialysis access program.

    abstract::Peritoneal dialysis (PD) is an underutilized form of renal replacement therapy. Recent data have emphasized that only 12% of end-stage renal disease (ESRD) patients are initiated on this form of therapy in the United States. Patients requiring PD have most often been referred to general surgeons for catheter placement...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章


    authors: Asif A,Byers P,Gadalean F,Roth D

    更新日期:2003-05-01 00:00:00

  • What is so bad about reverse epidemiology anyway?

    abstract::The term "reverse epidemiology" is used to indicate that such surrogates of cardiovascular risk and metabolic syndrome as obesity, hypercholesterolemia and hypertension are paradoxically associated with greater survival in individuals with chronic disease states and wasting, including dialysis patients, in whom the sh...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Kalantar-Zadeh K

    更新日期:2007-11-01 00:00:00

  • Methods of assessment of volume status and intercompartmental fluid shifts in hemodialysis patients: implications in clinical practice.

    abstract::Determining dry weight and assessing extracellular fluid volume in hemodialysis (HD) patients is one of the greatest challenges to practicing nephrologists. The clinical examination has limited accuracy, so different strategies have been investigated to aid in this evaluation. Biochemical markers of volume overload (A...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Ishibe S,Peixoto AJ

    更新日期:2004-01-01 00:00:00

  • Minerals in dialysis therapy: an introduction.

    abstract::The 180 l of glomerular filtrate formed each day contain some 1100 g (2.5 pounds) of sodium chloride, of which only 5-10 g are excreted in the urine--95% is reabsorbed by the tubules. Some 425 g (nearly a pound) of sodium bicarbonate and 145 g of glucose are filtered, and more than 99% of both are reabsorbed. Also fil...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章


    authors: Weisberg LS,Zanger R

    更新日期:2010-11-01 00:00:00

  • Surface-treated catheters--a review.

    abstract::Almost 30% of prevalent hemodialysis patients use catheters for vascular access although outcomes are superior with the use of either an arteriovenous fistula or a synthetic graft. Catheter complications are a major cause of morbidity and mortality for hemodialysis patients and increase the burden on the health care s...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Dwyer A

    更新日期:2008-11-01 00:00:00

  • Wishful Thinking: The Surprisingly Sparse Evidence for a Relationship between Oxidative Stress and Cardiovascular Disease in Hemodialysis Patients.

    abstract::The increased frequency of cardiovascular disease observed in hemodialysis patients is secondary to the combination of many traditional (age, male sex, hypertension, smoking, diabetes mellitus, and dyslipidemia) and novel and uremia-related (inflammation, uremic toxins, adipokine imbalance, coagulation disorders, prot...

    journal_title:Seminars in dialysis

    pub_type: 社论,评审


    authors: Bossola M,Tazza L

    更新日期:2015-05-01 00:00:00

  • Controversies in timing of dialysis initiation and the role of race and demographics.

    abstract::Dialysis remains the predominant form of renal replacement therapy in the United States, but the optimal timing for the initiation of dialysis remains poorly defined. Not only clinical factors such as signs/symptoms of uremia, co-existing cardiovascular disease, and presence of diabetes but also key demographic charac...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Streja E,Nicholas SB,Norris KC

    更新日期:2013-11-01 00:00:00

  • Electrolyte disturbances in the intensive care unit.

    abstract::The development of many electrolyte disturbances in the ICU can be prevented by attention to the use of intravenous fluids and nutrition. Hyponatremia is a relative contraindication to the use of hypotonic intravenous fluids and hypernatremia calls for the administration of water. Formulae have been devised to guide t...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章,评审


    authors: Sedlacek M,Schoolwerth AC,Remillard BD

    更新日期:2006-11-01 00:00:00

  • How I do it: endovascular treatment of arteriovenous graft pseudoaneurysms-watch out for the mouth.

    abstract::We present a case of arteriovenous graft pseudoaneurysms treated endovascularly with stent grafts and make suggestions regarding the technique of evaluating the pseudoaneurysms and choosing the proper location to deploy the stent grafts to maximize the outcomes and minimize the length of the graft covered by the stent...

    journal_title:Seminars in dialysis

    pub_type: 杂志文章


    authors: Florescu MC,Fillaus JA,Plumb TJ

    更新日期:2014-03-01 00:00:00

  • Cerebral ischemia during hemodialysis-finding the signal in the noise.

    abstract::Hemodialysis patients have multiple risk factors for small vessel cerebrovascular disease and cognitive dysfunction. Hemodialysis itself may cause clinically significant neurological injury through repetitive cerebral ischemia. However, supporting evidence to date consists of epidemiological associations, expert opini...

    journal_title:Seminars in dialysis

    pub_type: 社论,评审


    authors: MacEwen C,Watkinson P,Tarassenko L,Pugh C

    更新日期:2018-05-01 00:00:00