Cardiovascular adaptations associated with exercise in patients on hemodialysis.

abstract：:Cardiovascular complications are the leading cause of mortality in patients with end-stage renal disease (ESRD). The excess cardiovascular risk and mortality is already demonstrable in early renal disease and in patients with chronic renal failure (CRF), with the highest relative risk of mortality in the youngest pati...

journal_title：Seminars in dialysis

authors： London GM

更新日期：2003-03-01 00:00:00

abstract：:As suggested by its American brand name (Sensipar), the calcimimetic cinacalcet sensitizes the parathyroid cells to the extracellular calcium signal, suppressing parathyroid hormone (PTH) release and synthesis and preventing parathyroid cell proliferation. This primary PTH suppression decreases the release of calcium ...

journal_title：Seminars in dialysis

authors： Shahapuni I,Mansour J,Harbouche L,Maouad B,Benyahia M,Rahmouni K,Oprisiu R,Bonne JF,Monge M,El Esper N,Presne C,Moriniere P,Choukroun G,Fournier A

更新日期：2005-05-01 00:00:00

abstract：:There is abundant evidence that chronic renal failure (CRF) and end-stage renal disease (ESRD) alter drug disposition by affecting protein and tissue binding and reducing systemic clearance of renally cleared drugs. What is not fully appreciated is that CRF can significantly reduce nonrenal clearance and alter the bio...

journal_title：Seminars in dialysis

authors： Dreisbach AW,Lertora JJ

更新日期：2003-01-01 00:00:00

abstract：:Hyperkalemia contributes significantly to high mortality among ESRD patients. Excess intake and inadequate removal are the most common etiologies in HD patients. Although dialysis is the definitive treatment, classical medical therapy must be employed as a temporizing measure to acutely lower serum potassium. Reducing...

journal_title：Seminars in dialysis

authors： Pani A,Floris M,Rosner MH,Ronco C

更新日期：2014-11-01 00:00:00

abstract：:Hemodialysis patients have multiple risk factors for small vessel cerebrovascular disease and cognitive dysfunction. Hemodialysis itself may cause clinically significant neurological injury through repetitive cerebral ischemia. However, supporting evidence to date consists of epidemiological associations, expert opini...

journal_title：Seminars in dialysis

authors： MacEwen C,Watkinson P,Tarassenko L,Pugh C

更新日期：2018-05-01 00:00:00

abstract：:Renal osteodystrophy (ROD) represents a spectrum of bone lesions ranging from a high-turnover to a low-turnover state. The expression of the histologic bone lesions is modulated by parathyroid hormone (PTH), vitamin D, calcium, phosphorus, and aluminum that act as major regulators of osteoblastic activity and bone for...

journal_title：Seminars in dialysis

authors： Hernandez JD,Wesseling K,Salusky IB

更新日期：2005-07-01 00:00:00

abstract：:Dialysis remains the predominant form of renal replacement therapy in the United States, but the optimal timing for the initiation of dialysis remains poorly defined. Not only clinical factors such as signs/symptoms of uremia, co-existing cardiovascular disease, and presence of diabetes but also key demographic charac...

journal_title：Seminars in dialysis

authors： Streja E,Nicholas SB,Norris KC

更新日期：2013-11-01 00:00:00

abstract：:Hemodialysis patient outcomes are often suboptimal, with one-sixth of patients receiving an inadequate dialysis dose, one-fourth using catheters for vascular access, and more than one-half being malnourished. This review describes a four-step approach for improving dialysis patient outcomes. First, select an outcome t...

journal_title：Seminars in dialysis

authors： Sehgal AR

更新日期：2002-01-01 00:00:00

abstract：:Physical examination (PE) is an excellent means of predicting arteriovenous fistula (AVF) dysfunction. Although quick and inexpensive, PE is seldom used as a tool to assess stenosis by general nephrologists, dialysis nurses, and dialysis technicians. Previous studies have demonstrated that PE can be taught to interven...

journal_title：Seminars in dialysis

authors： Rosenberg JE,Yevzlin AS,Chan MR,Valliant AM,Astor BC

更新日期：2015-09-01 00:00:00

abstract：:In addition to extracorporeal renal replacement strategies, which in chronic kidney disease (CKD) are largely reserved for the treatment of end-stage kidney failure, conservative measures can be taken to reduce concentration, effects, or both concentration and effects of uremic retention solutes. In this overview, we ...

journal_title：Seminars in dialysis

authors： Vanholder R,Argilés A,Beige J,Brunet P,Drüeke TB,Fliser D,Herget-Rosenthal S,Hörl WH,Jörres A,Perna A,Rodriguez-Portillo M,Spasovski G,Stegmayr B,Stenvinkel P,Wanner C,Wiecek A,Massy ZA

更新日期：2009-07-01 00:00:00

abstract：:Heart failure (HF) is very common in the general population, and risk factors for HF, such as coronary artery disease, diabetes, obesity, and hypertension, are frequently present in patients with CKD. Therefore, HF is also an important cause of morbidity and mortality in this population. Diastolic heart failure (DHF),...

journal_title：Seminars in dialysis

authors： Pecoits-Filho R,Bucharles S,Barberato SH

更新日期：2012-01-01 00:00:00

abstract：:National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF KDOQI) guidelines recommend Doppler ultrasound (DU) for surveillance of vascular access (VA), but trials have not been unanimous about its benefit on VA patency. The aim of this study was to evaluate the accuracy of DU for patency, as well as t...

journal_title：Seminars in dialysis

authors： Guedes Marques M,Ibeas J,Botelho C,Maia P,Ponce P

更新日期：2015-03-01 00:00:00

abstract：:Until the discovery of calcimimetics, the management of secondary hyperparathyroidism (SHPT) relied exclusively on treatment with phosphate binders, vitamin D derivatives or surgical parathyroidectomy with limited success. The therapeutic use of calcimimetic agents, together with a better understanding of the pivotal ...

journal_title：Seminars in dialysis

authors： Rodríguez M,Goodman WG,Liakopoulos V,Messa P,Wiecek A,Cunningham J

更新日期：2015-09-01 00:00:00

abstract：:Recent experimental and clinical studies suggest the possible utility of niacin (nicotinic acid, vitamin B3) and its metabolite nicotinamide as a means of lowering phosphate levels in dialysis patients via direct inhibition of the Na-Pi-2b sodium-dependent phosphate co-transporter in the GI tract. While the possibilit...

journal_title：Seminars in dialysis

authors： Berns JS

更新日期：2008-05-01 00:00:00

abstract：:Home hemodialysis is not a new therapy; rather it is a therapy in which interest has been rekindled due to both the continually growing end-stage renal disease population and concern about poor outcomes in patients on conventional thrice-weekly in-center dialysis. The practical issues to be considered when starting a ...

journal_title：Seminars in dialysis

authors： Moran J,Kraus M

更新日期：2007-01-01 00:00:00

abstract：:Appropriate antibiotic dosing in critically ill, infected, patients receiving continuous renal replacement therapy (CRRT) is crucial to improve patient outcomes. Severe sepsis and septic shock result in changes in pharmacokinetic parameters, including increased volume of distribution, hypoalbuminemia, and changes in r...

journal_title：Seminars in dialysis

authors： Shaw AR,Chaijamorn W,Mueller BA

更新日期：2016-07-01 00:00:00

abstract：:A patient with newly diagnosed end-stage renal disease (ESRD) received a femoral catheter for hemodialysis (HD). Shortly thereafter he developed fever, and blood cultures grew methicillin-resistant Staphylococcus aureus. The catheter was removed and the patient was treated with both vancomycin and rifampin; however, b...

journal_title：Seminars in dialysis

authors： Chang CS,Thajeb P,Chen HH,Wu CJ

更新日期：2005-07-01 00:00:00

abstract：:Dialysis-related amyloidosis (DRA) is a serious complication in long-term dialysis patients, and presents with carpal tunnel syndrome, cystic bone lesions, destructive spondylarthropathy, diffuse arthritis and periarthritis, systemic organ involvement, and dialysis-related spinal canal stenosis (DSCS). Recently a new ...

journal_title：Seminars in dialysis

authors： Niwa T

更新日期：2001-03-01 00:00:00

abstract：:Withholding and withdrawal of dialysis has been a reality since dialysis was invented. Only in the past 20 years has it been formally studied, and we still have a great deal to learn. The nephrology community has slowly come to accept that, for some of our patients, not having dialysis is a better option than continui...

journal_title：Seminars in dialysis

authors： Germain MJ,Cohen LM,Davison SN

更新日期：2007-05-01 00:00:00

abstract：:Nephrologists offer renal replacement therapy (RRT) to patients who are unlikely to benefit in part because of our discomfort discussing goals of care in the setting of an uncertain prognosis for a given individual. Permanent neurological impairment, terminal illness (life expectancy <6 months), medical conditions pre...

journal_title：Seminars in dialysis

authors： Holley JL

更新日期：2016-07-01 00:00:00

abstract：:Dialysate leakage represents a major noninfectious complication of peritoneal dialysis (PD). An exit-site leak refers to the appearance of any moisture around the PD catheter identified as dialysate; however, the spectrum of dialysate leaks also includes any dialysate loss from the peritoneal cavity other than via the...

journal_title：Seminars in dialysis

authors： Leblanc M,Ouimet D,Pichette V

更新日期：2001-01-01 00:00:00

abstract：:Pulmonary hypertension (PH) is a progressive, fatal pulmonary circulatory disease that accompanies many conditions (including left to right side shunt) with compensatory elevated cardiac output. PH also complicates chronic hemodialysis (HD) therapy immediately after the creation of an arteriovenous (AV) access, even b...

journal_title：Seminars in dialysis

authors： Yigla M,Abassi Z,Reisner SA,Nakhoul F

更新日期：2006-09-01 00:00:00

abstract：:The risk of intradialytic hypotension (IDH) is determined by various factors, among them dialysis modality and dialyzer membrane. We conducted a literature search in PubMed on November 1, 2016 and selected relevant randomized controlled and cross-over trials, and prospective and retrospective cohort studies published ...

journal_title：Seminars in dialysis

authors： Patel S,Raimann JG,Kotanko P

更新日期：2017-11-01 00:00:00

abstract：:Mounting evidence supports a strong association between fluid management and outcomes among individuals receiving maintenance hemodialysis. The speed of fluid removal during dialysis (ultrafiltration, UF) is a modifiable aspect of fluid management that has attracted recent attention as a potential performance measure ...

journal_title：Seminars in dialysis

authors： Flythe JE

更新日期：2016-11-01 00:00:00

abstract：:Dysfunction of arteriovenous fistulas (AVF) and arteriovenous grafts (AVG) contribute significantly to morbidity and hospitalization in the dialysis population. Despite advances in endovascular techniques, the incidence of vascular access stenosis remains problematic. Currently, the role of endovascular stent placemen...

journal_title：Seminars in dialysis

authors： Fu N,Joachim E,Yevzlin AS,Shin JI,Astor BC,Chan MR

更新日期：2015-05-01 00:00:00

abstract：:There are studies reporting that soluble kltho (sKlotho) deficiency plays a role in cardiovascular disease in addition to traditional risk factors such as diabetes, hypertension, anemia, smoking, and excessive volume burden. Our aim in this study was to investigate the relationship of sKlotho with uremic cardiomyopath...

journal_title：Seminars in dialysis

authors： Erkus E,Buyukterzı Z,Karakose S,Kurku H,Kurtgoz PO,Topal M,Guney I

更新日期：2020-11-30 00:00:00

abstract：:While oral diuretics are commonly used in patients with chronic kidney disease for the management of volume and blood pressure, they are often discontinued upon initiation of dialysis. We suggest that diuretics are considerably underutilized in peritoneal dialysis and haemodialysis patients despite numerous potential ...

journal_title：Seminars in dialysis

authors： Trinh E,Bargman JM

更新日期：2016-09-01 00:00:00

abstract：:United States standards for the microbiologic quality of dialysate are not very stringent and have remained unchanged for more than 20 years, despite significant changes in the patient population and in the technology of hemodialysis. Numerous studies have demonstrated that bacterial products can cross dialysis membra...

journal_title：Seminars in dialysis

authors： Ward RA

更新日期：2000-11-01 00:00:00

abstract：:Alternate night nocturnal hemodialysis (HD) is a popular modality in Australia. This modality grew out of a desire to increase the availability and accessibility of nocturnal HD without incurring excessive costs. It has proven popular with staff, patients, and administrators. There are limited data to support the bene...

journal_title：Seminars in dialysis

authors： Kerr PG,Agar JW,Hawley CM

更新日期：2011-11-01 00:00:00

abstract：:The development of pleural effusions in ESRD patients is a relatively common occurrence. Uremia, currently a rare cause of effusion, can lead to the development of hemorrhagic pleural fluid collections in patients who are underdialyzed. Uremic pleural effusions should be considered when common etiologies of effusions ...

journal_title：Seminars in dialysis

authors： Krishnan M,Choi M

更新日期：2001-05-01 00:00:00