We Wait Too Long to Refer Patients for Transplantation.

abstract：:In response to rapid alkali delivery during hemodialysis, hydrogen ions (H+ ) are mobilized from body buffers and from stimulation of organic acid production in amounts sufficient to convert most of the delivered bicarbonate to CO2 and water. Release of H+ from nonbicarbonate buffers serves to back-titrate them to a m...

journal_title：Seminars in dialysis

authors： Sargent JA,Marano M,Marano S,Gennari FJ

更新日期：2019-05-01 00:00:00

abstract：:Parenteral iron is used to restore the body's iron pool before and during erythropoiesis-stimulating agent (ESA) therapy; together these agents form the backbone of anemia management in end-stage renal disease (ESRD) patients undergoing hemodialysis. ESRD patients receiving chronic intravenous iron products, which exc...

journal_title：Seminars in dialysis

authors： Rostoker G

更新日期：2019-01-01 00:00:00

abstract：:National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF KDOQI) guidelines recommend Doppler ultrasound (DU) for surveillance of vascular access (VA), but trials have not been unanimous about its benefit on VA patency. The aim of this study was to evaluate the accuracy of DU for patency, as well as t...

journal_title：Seminars in dialysis

authors： Guedes Marques M,Ibeas J,Botelho C,Maia P,Ponce P

更新日期：2015-03-01 00:00:00

abstract：:Nephrologists offer renal replacement therapy (RRT) to patients who are unlikely to benefit in part because of our discomfort discussing goals of care in the setting of an uncertain prognosis for a given individual. Permanent neurological impairment, terminal illness (life expectancy <6 months), medical conditions pre...

journal_title：Seminars in dialysis

authors： Holley JL

更新日期：2016-07-01 00:00:00

abstract：:There is clear evidence that survival rates following transplantation far exceed those for remaining on dialysis, regardless of body size measured by body mass index (BMI). Studies over the past 15 years also suggest little to no difference in long-term outcomes, including graft survival and mortality, irrespective of...

journal_title：Seminars in dialysis

authors： MacLaughlin HL,Campbell KL

更新日期：2019-05-01 00:00:00

abstract：:While patients with sickle cell disease currently constitute a very small minority of the US dialysis population (0.1%), there is anticipated growth of this group as the life expectancy of those with sickle cell disease (SCD) increases. SCD patients suffer a high burden of morbidity, which is enhanced by the presence ...

journal_title：Seminars in dialysis

authors： Boyle SM,Jacobs B,Sayani FA,Hoffman B

更新日期：2016-01-01 00:00:00

abstract：:Despite improvements in the delivery of care, the annual all-cause mortality rate for end-stage renal disease (ESRD) patients is still around 220 deaths per 1000 at risk patient-years. Infection-related causes are second only to cardiovascular events as a cause for mortality among ESRD patients. Almost two-thirds of a...

journal_title：Seminars in dialysis

authors： Camins BC

更新日期：2013-07-01 00:00:00

abstract：:In this article we deal with three aspects of acidosis in patients with chronic renal insufficiency: clinical characteristics, pathophysiology, and therapeutic approach. ...

journal_title：Seminars in dialysis

authors： Uribarri J

更新日期：2000-07-01 00:00:00

abstract：:Patients on hemodialysis are physically inactive. Less than 50% of hemodialysis patients undertake exercise once a week and such patients have increased mortality compared to patients who undertake regular exercise. The reasons for physical inactivity and reduced functional capacity are complex and inter-related, with...

journal_title：Seminars in dialysis

authors： Graham-Brown MPM,Jardine MJ,Burton JO

更新日期：2019-07-01 00:00:00

abstract：:This article reviews the pharmacokinetic characteristics of calcitriol, paricalcitol, and doxercalciferol, and provides an overview of the metabolism of vitamin D. Calcitriol and paricalcitol have similar pharmacokinetic profiles, with terminal half-lives ranging from 5 to 10 hours in healthy subjects to 15-30 hours i...

journal_title：Seminars in dialysis

authors： Bailie GR,Johnson CA

更新日期：2002-09-01 00:00:00

abstract：:Bacteremia is a common infectious complication in hemodialysis patients. Metastatic sites of infection including infective endocarditis, vertebral osteomyelitis, spinal epidural abscess, and septic arthritis occur relatively frequently. These complications are associated with increased morbidity and mortality in hemod...

journal_title：Seminars in dialysis

authors： Lewis SS,Sexton DJ

更新日期：2013-01-01 00:00:00

abstract：:Intradialytic hypotension (IDH) is a common complication of hemodialysis and is associated with numerous adverse outcomes including cardiovascular events, inadequate dialysis, loss of vascular access, and death. It is estimated that approximately 20%-30% of all dialysis sessions are affected by IDH. In seeking ways to...

journal_title：Seminars in dialysis

authors： Chang TI

更新日期：2017-11-01 00:00:00

abstract：:Dialysis patients are at high risk for fracture, with published rates in excess of a 20% probability of fracture over the next 10 years of dialysis. Unfortunately, there is no accepted methodology for quantifying this risk in advance of the first fracture; conventional bone densitometry performs unreliably in this rol...

journal_title：Seminars in dialysis

authors： Jamal SA,Hodsman AB

更新日期：2011-01-01 00:00:00

abstract：:This report reviews the most common surgical interventions and complications of chronic peritoneal dialysis (PD) patients. Based on the current knowledge as well as our experience we detail the role of these surgical procedures. We supplement the reported knowledge in the field with our own experience in this area. Th...

journal_title：Seminars in dialysis

authors： Ratajczak A,Lange-Ratajczak M,Bobkiewicz A,Studniarek A

更新日期：2017-01-01 00:00:00

abstract：:The use of stents has been steadily increasing in the management of dialysis access dysfunction. The purpose of this report was to review the use of covered stents in failed forearm fistulas and describe a case of the use of a small caliber forearm covered stent in a early failed forearm fistula that allowed dialysis ...

journal_title：Seminars in dialysis

authors： Ross JL

更新日期：2009-01-01 00:00:00

abstract：:The etiology and management of intradialytic hypotension has become an increasingly complex issue. Volume depletion due to ultrafiltration remains the predominant underlying etiologic factor. However, patients vary markedly in their hemodynamic tolerance to fluid removal. While many risk factors have been identified, ...

journal_title：Seminars in dialysis

authors： Sherman RA

更新日期：2002-05-01 00:00:00

abstract：:Dialysis-related amyloidosis (DRA) is a serious complication in long-term dialysis patients, and presents with carpal tunnel syndrome, cystic bone lesions, destructive spondylarthropathy, diffuse arthritis and periarthritis, systemic organ involvement, and dialysis-related spinal canal stenosis (DSCS). Recently a new ...

journal_title：Seminars in dialysis

authors： Niwa T

更新日期：2001-03-01 00:00:00

abstract：:Home dialysis (home HD or home PD) remains underutilized in most jurisdictions. Physicians, advanced-practice nurses, and policy makers working with chronic kidney disease populations can provide insights into patient, healthcare professional, and system-level barriers to home dialysis selection by suitable patients. ...

journal_title：Seminars in dialysis

authors： Osterlund K,Mendelssohn D,Clase C,Guyatt G,Nesrallah G

更新日期：2014-03-01 00:00:00

abstract：:A procedure-related complication is an unanticipated adverse event that requires therapy. In order to analyze frequency and severity of complications in the process of quality assurance, it is useful to have a classification of complications, indicating the type and severity. The Clinical Practice Committee of America...

journal_title：Seminars in dialysis

authors： Vesely TM,Beathard G,Ash S,Hoggard J,Schon D,ASDIN Clinical Practice Committee.

更新日期：2007-07-01 00:00:00

abstract：:Renal osteodystrophy (ROD) represents a spectrum of bone lesions ranging from a high-turnover to a low-turnover state. The expression of the histologic bone lesions is modulated by parathyroid hormone (PTH), vitamin D, calcium, phosphorus, and aluminum that act as major regulators of osteoblastic activity and bone for...

journal_title：Seminars in dialysis

authors： Hernandez JD,Wesseling K,Salusky IB

更新日期：2005-07-01 00:00:00

abstract：:Recent experimental and clinical studies suggest the possible utility of niacin (nicotinic acid, vitamin B3) and its metabolite nicotinamide as a means of lowering phosphate levels in dialysis patients via direct inhibition of the Na-Pi-2b sodium-dependent phosphate co-transporter in the GI tract. While the possibilit...

journal_title：Seminars in dialysis

authors： Berns JS

更新日期：2008-05-01 00:00:00

abstract：:Iodinated contrast agents are well tolerated in ESRD patients. Certain types of ICM, i.e., LOCM and the nonionic agents are associated with better safety profiles. Current available evidence, although not optimal, does not support the need for additional hemodialysis for ICM removal to preserve residual renal function...

journal_title：Seminars in dialysis

authors： Khan SF,Kalantari K

更新日期：2014-11-01 00:00:00

abstract：:To prevent pyrogenic reactions during hemodialysis, it is recommended that bacteria and endotoxin in dialysate not exceed 100-200 colony forming units (CFU)/ml and 0.25-2 endotoxin units (EU)/ml, respectively. While these limits are adequate to prevent acute pyrogenic reactions, data are accumulating to suggest they m...

journal_title：Seminars in dialysis

authors： Ward RA

更新日期：2004-11-01 00:00:00

abstract：:Presternally exiting peritoneal dialysis (PD) catheters have been described as advantageous compared to abdominally exiting catheters with regard to infection, wound healing, and other complications. Placement of such catheters has only been described with open surgical techniques and not by percutaneous means. In thi...

journal_title：Seminars in dialysis

authors： Sreenarasimhaiah VP,Margassery SK,Martin KJ,Bander SJ

更新日期：2004-09-01 00:00:00

abstract：:Hyperhomocysteinemia is an independent cardiovascular risk factor, according to most observational studies and to studies using the Mendelian randomization approach, utilizing the common polymorphism C677T of methylene tetrahydrofolate reductase. In contrast, the most recent secondary preventive intervention studies, ...

journal_title：Seminars in dialysis

authors： Perna AF,Ingrosso D,Violetti E,Luciano MG,Sepe I,Lanza D,Capasso R,Ascione E,Raiola I,Lombardi C,Stenvinkel P,Massy Z,De Santo NG

更新日期：2009-07-01 00:00:00

abstract：:Dysfunction of arteriovenous fistulas (AVF) and arteriovenous grafts (AVG) contribute significantly to morbidity and hospitalization in the dialysis population. Despite advances in endovascular techniques, the incidence of vascular access stenosis remains problematic. Currently, the role of endovascular stent placemen...

journal_title：Seminars in dialysis

authors： Fu N,Joachim E,Yevzlin AS,Shin JI,Astor BC,Chan MR

更新日期：2015-05-01 00:00:00

abstract：:Over the last 10 years an increasing number of patients worldwide have started dialysis or had transplantation. Many are elderly with complex comorbid conditions. Registries across the world all show a rapid and dramatic increase in the number of older patients accepted for renal replacement therapy. In addition, the ...

journal_title：Seminars in dialysis

authors： Krishnan M,Lok CE,Jassal SV

更新日期：2002-03-01 00:00:00

abstract：:Thrombosis is the leading cause of arteriovenous (AV) access failure for hemodialysis patients requiring frequent interventions. We describe a novel approach to the lyse-and-wait technique in thrombosed AV access using nurse-administered thrombolytics in a hospital-based hemodialysis unit. All patients at a single-cen...

journal_title：Seminars in dialysis

authors： Umanath K,Morrison RS,Christopher Wilbeck J,Schulman G,Bream P,Dwyer JP

更新日期：2013-01-01 00:00:00

abstract：:The term "reverse epidemiology" is used to indicate that such surrogates of cardiovascular risk and metabolic syndrome as obesity, hypercholesterolemia and hypertension are paradoxically associated with greater survival in individuals with chronic disease states and wasting, including dialysis patients, in whom the sh...

journal_title：Seminars in dialysis

authors： Kalantar-Zadeh K

更新日期：2007-11-01 00:00:00

abstract：:Automated peritoneal dialysis (APD) has experienced significant growth in highly developed nations in the last few years, while in developing countries with important social, educational, and financial constraints this treatment modality is, at best, trying to emerge. APD offers advantages that make it popular. Some o...

journal_title：Seminars in dialysis

authors： Correa-Rotter R

更新日期：2002-11-01 00:00:00